香豆素
香豆素
基本信息
香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。
结构特征香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。
自然来源香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。
化学性质 稳定性由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。
生物活性许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。
应用领域 医药行业在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。
食品工业由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。
其他应用此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。
生产方法香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。
总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。
相关化合物
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| —— | 3,7-Benzofurandiol, 2,3-dihyro-2,2-dimethyl-, 7-carbamate | 98874-79-4 | C11H13NO4 |
|
| —— | 2-dimethylhydroxymethylvinylidene-3-piperidino-3H-benzofuran | 165402-24-4 | C17H23NO2 |
|
| —— | Carbamic acid, (((((2,4-dimethylphenyl)imino)methyl)methylamino)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 104946-77-2 | C22H27N3O3S |
|
| —— | Carbamic acid, methylnitroso-, 2,2-dimethyl-3-hydroxy-2,3-dihydro-7-benzofuranyl ester | 100836-60-0 | C12H14N2O5 |
|
| —— | 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, N-hydroxycarbamate | 100347-65-7 | C11H13NO4 |
|
| —— | 4-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, carbamate | 100347-64-6 | C11H13NO3 |
|
| —— | 2-Ethyl-N-(3-methoxy-propyl)-<3>cumaranylmethylamin | 94326-36-0 | C15H23NO2 |
|
| —— | 2-Ethyl-<3>cumaranylmethylamin | 91245-86-2 | C11H15NO |
|
| —— | 2,3-dihydro-2,2-dimethyl-7-benzofuranyl(isopropoxysulfenyl)(methyl)carbamate | 86627-64-7 | C15H21NO4S |
|
| —— | 2,N-Diethyl-<3>cumaranylmethylamin | 92195-77-2 | C13H19NO |
|
| —— | Carbamic acid, ((cyclohexyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-66-9 | C18H25NO4S |
|
| —— | Carbamic acid, (((4-(1,1-dimethylethyl)phenyl)methoxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-80-7 | C23H29NO4S |
|
| —— | Carbamic acid, ((1,1-dimethylethoxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-76-1 | C16H23NO4S |
|
| —— | Carbamic acid, (ethoxythio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-63-6 | C14H19NO4S |
|
| —— | Carbamic acid, (methoxydithio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-74-9 | C13H17NO4S2 |
|
| —— | Carbamic acid, ((dodecyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-68-1 | C24H39NO4S |
|
| —— | Carbamic acid, ((decyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-78-3 | C22H35NO4S |
|
| —— | Carbamic acid, ((hexyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-65-8 | C18H27NO4S |
|
| —— | Carbamic acid, methyl((octyloxy)thio)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-77-2 | C20H31NO4S |
|
| —— | Carbamic acid, ((hexyloxy)dithio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-73-8 | C18H27NO4S2 |
|
| —— | Carbamic acid, methyl((octadecyloxy)thio)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-81-8 | C30H51NO4S |
|
| —— | Carbamic acid, ((1-ethylpropoxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-75-0 | C17H25NO4S |
|
| —— | Carbamic acid, methyl((phenylmethoxy)thio)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 86627-67-0 | C19H21NO4S |
|
| —— | ((2,6-Xylyl)sulfinyl)methylcarbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 77248-44-3 | C20H23NO5S |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-pentoxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-31-5 | C19H28N2O5S |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-octyloxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-33-7 | C22H34N2O5S |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-heptyloxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-32-6 | C21H32N2O5S |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-isopropoxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-29-1 | C17H24N2O5S |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-propoxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-28-0 | C17H24N2O5S |
|
| —— | (+)-2-isopropenyl-2,3-dihydrobenzofuran-5-methanol | 63587-65-5 | C12H14O2 |
|
| —— | Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-decyloxycarbonylaminothio)-N-methylcarbamoyloxy)- | 65907-34-8 | C24H38N2O5S |
|
| —— | 3-[1-(Diethylamino)propan-2-yl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-62-4 | C21H26ClNO2 |
|
| —— | 3-[2-(Diethylamino)propyl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-63-5 | C21H26ClNO2 |
|
| —— | 3-<γ-Morpholinopropyl>-3-phenyl-2-benzofuranon-Hydrochlorid | 63917-68-0 | C21H23NO3*ClH |
|
| —— | 3-[11-(Diethylamino)undecyl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-65-7 | C29H42ClNO2 |
|
| —— | 3-<β-Morpholinoaethyl>-3-phenyl-2-benzofuranon Hydrochlorid | 63917-67-9 | C20H21NO3*ClH |
|
| —— | 3-[3-(Diethylamino)propyl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-64-6 | C21H26ClNO2 |
|
| —— | 3-[3-(Dibutylamino)propyl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-60-2 | C25H34ClNO2 |
|
| —— | 3-[2-(Dimethylamino)ethyl]-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-66-8 | C18H20ClNO2 |
|
| —— | 3-[2-(Diethylamino)ethyl]-5-methyl-3-phenyl-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-61-3 | C21H26ClNO2 |
|
| —— | 3-Phenyl-3-[2-(piperidin-1-yl)ethyl]-1-benzofuran-2(3H)-one--hydrogen chloride (1/1) | 63917-69-1 | C21H24ClNO2 |
|
| —— | Methyl((2-methylphenyl)sulfinyl)carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 57020-68-5 | C19H21NO4S |
|
| —— | 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl (3-methylphenylthio)(methyl)carbamate | 50539-68-9 | C19H21NO3S |
|
| —— | Carbamic acid, thiobis(methyl-, bis(2,3-dihydro-2,2-dimethyl-7-benzofuranyl) ester | 50673-14-8 | C24H28N2O6S |
|
| —— | Carbamic acid, ((4-chlorophenyl)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 50539-73-6 | C18H18ClNO3S |
|
| —— | Carbamic acid, ((p-bromophenyl)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 50539-74-7 | C18H18BrNO3S |
|
| —— | Carbamic acid, ((4-cyanophenyl)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 50539-77-0 | C19H18N2O3S |
|
| —— | Carbamic acid, ((p-tert-butylphenyl)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 50539-70-3 | C22H27NO3S |
|
| —— | Carbamic acid, (ethylthio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester | 50539-81-6 | C14H19NO3S |
|
| —— | 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl (methyl)(pentachlorophenylthio)carbamate | 50539-76-9 | C18H14Cl5NO3S |
|
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- 11
- 12
- 13
- 14
- 15
- 16
- 17
- 18
- 19
- 20
- 21
- 22
- 23
- 24
- 25
- 26
- 27
- 28
- 29
- 30
- 31
- 32
- 33
- 34
- 35
- 36
- 37
- 38
- 39
- 40
- 41
- 42
- 43
- 44
- 45
- 46
- 47
- 48
- 49
- 50
- 51
- 52
- 53
- 54
- 55
- 56
- 57
- 58
- 59
- 60
- 61
- 62
- 63
- 64
- 65
- 66
- 67
- 68
- 69
- 70
- 71
- 72
- 73
- 74
- 75
- 76
- 77
- 78
- 79
- 80
- 81
- 82
- 83
- 84
- 85
- 86
- 87
- 88
- 89
- 90
- 91
- 92
- 93
- 94
- 95
- 96
- 97
- 98
- 99
- 100
- 101
- 102
- 103
- 104
- 105
- 106
- 107
- 108
- 109
- 110
- 111
- 112
- 113
- 114
- 115
- 116
- 117
- 118
- 119
- 120
- 121
- 122
- 123
- 124
- 125
- 126
- 127
- 128
- 129
- 130
- 131
- 132
- 133
- 134
- 135
- 136
- 137
- 138
- 139
- 140
- 141
- 142
- 143
- 144
- 145
- 146
- 147
- 148
- 149
- 150
- 151
- 152
- 153
- 154
- 155
- 156
- 157
- 158
- 159
- 160
- 161
- 162
- 163
- 164
- 165
- 166
- 167
- 168
- 169
- 170
- 171
- 172
- 173
- 174
- 175
- 176
- 177
- 178
- 179
- 180
- 181
- 182
- 183
- 184
- 185
- 186
- 187
- 188
- 189
- 190
- 191
- 192
- 193
- 194
- 195
- 196
- 197
- 198
- 199
- 200
- 201
- 202
- 203
- 204
- 205
- 206
- 207
- 208
- 209
- 210
- 211
- 212
- 213
- 214
- 215
- 216
- 217
- 218
- 219
- 220
- 221
- 222
- 223
- 224
- 225
- 226
- 227
- 228
- 229
- 230
- 231
- 232
- 233
- 234
- 235
- 236
- 237
- 238
- 239
- 240
- 241
- 242
- 243
- 244
- 245
- 246
- 247
- 248
- 249
- 250
- 251
- 252
- 253
- 254
- 255
- 256
- 257
- 258
- 259
- 260
- 261
- 262
- 263
- 264
- 265
- 266
- 267
- 268
- 269
- 270
- 271
- 272
- 273
- 274
- 275
- 276
- 277
- 278
- 279
- 280
- 281
- 282
- 283
- 284
- 285
- 286
- 287
- 288
- 289
- 290
- 291
- 292
- 293
- 294
- 295
- 296
- 297
- 298
- 299
- 300
联系我们
关注我们
公众号
