摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2,3-dihydro-1-benzofuran-7-carboxamide —— C15H19NO4S
    N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2,3-dihydro-1-benzofuran-7-carboxamide
    —— [(2R)-2,3-dihydro-1-benzofuran-2-yl]-[4-[(3-methylpyridin-2-yl)methyl]piperazin-1-yl]methanone —— C20H23N3O2
    [(2R)-2,3-dihydro-1-benzofuran-2-yl]-[4-[(3-methylpyridin-2-yl)methyl]piperazin-1-yl]methanone
    —— [(2R)-5-methyl-7-[6-(1-methylimidazol-2-yl)pyridazin-3-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H19N5O
    [(2R)-5-methyl-7-[6-(1-methylimidazol-2-yl)pyridazin-3-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-5-methyl-7-[6-(1-methylimidazol-2-yl)pyridazin-3-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H19N5O
    [(2S)-5-methyl-7-[6-(1-methylimidazol-2-yl)pyridazin-3-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(5,6-dimethylpyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H18N2O
    [(2S)-7-(5,6-dimethylpyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(5,6-dimethylpyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H18N2O
    [(2R)-7-(5,6-dimethylpyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(5-ethylpyrimidin-2-yl)-4-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H16FN3O
    [(2S)-7-(5-ethylpyrimidin-2-yl)-4-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-chloro-5-(5-fluoropyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C13H11ClFN3O
    [(2R)-7-chloro-5-(5-fluoropyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(5-ethylpyrimidin-2-yl)-4-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H16FN3O
    [(2R)-7-(5-ethylpyrimidin-2-yl)-4-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— 2-[(2S)-2-(aminomethyl)-5-chloro-2,3-dihydro-1-benzofuran-7-yl]-N,6-dimethylpyrimidin-4-amine —— C15H17ClN4O
    2-[(2S)-2-(aminomethyl)-5-chloro-2,3-dihydro-1-benzofuran-7-yl]-N,6-dimethylpyrimidin-4-amine
    —— 1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[[2-(furan-2-yl)-1,3-thiazol-4-yl]methyl]methanamine —— C17H16N2O2S
    1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[[2-(furan-2-yl)-1,3-thiazol-4-yl]methyl]methanamine
    —— 2-[(2R)-2-(aminomethyl)-5-chloro-2,3-dihydro-1-benzofuran-7-yl]-N,6-dimethylpyrimidin-4-amine —— C15H17ClN4O
    2-[(2R)-2-(aminomethyl)-5-chloro-2,3-dihydro-1-benzofuran-7-yl]-N,6-dimethylpyrimidin-4-amine
    —— 4-ethyl-2-methyl-5-[1-[[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methyl]piperidin-4-yl]-1,2,4-triazol-3-one —— C20H28N4O2
    4-ethyl-2-methyl-5-[1-[[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methyl]piperidin-4-yl]-1,2,4-triazol-3-one
    —— (3R)-1-[3-[2-(2,3-dihydro-1-benzofuran-5-yl)imidazol-1-yl]propyl]piperidin-3-ol —— C19H25N3O2
    (3R)-1-[3-[2-(2,3-dihydro-1-benzofuran-5-yl)imidazol-1-yl]propyl]piperidin-3-ol
    —— 4-ethyl-2-methyl-5-[1-[[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methyl]piperidin-4-yl]-1,2,4-triazol-3-one —— C20H28N4O2
    4-ethyl-2-methyl-5-[1-[[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methyl]piperidin-4-yl]-1,2,4-triazol-3-one
    —— 4-[(2R)-2-(aminomethyl)-5-fluoro-2,3-dihydro-1-benzofuran-7-yl]-6-methoxypyrimidin-2-amine —— C14H15FN4O2
    4-[(2R)-2-(aminomethyl)-5-fluoro-2,3-dihydro-1-benzofuran-7-yl]-6-methoxypyrimidin-2-amine
    —— 4-[(2S)-2-(aminomethyl)-5-fluoro-2,3-dihydro-1-benzofuran-7-yl]-6-methoxypyrimidin-2-amine —— C14H15FN4O2
    4-[(2S)-2-(aminomethyl)-5-fluoro-2,3-dihydro-1-benzofuran-7-yl]-6-methoxypyrimidin-2-amine
    —— 5-[(2S)-2-(aminomethyl)-5-methyl-2,3-dihydro-1-benzofuran-7-yl]-2-benzyl-N,N-dimethyl-1,2,4-triazol-3-amine —— C21H25N5O
    5-[(2S)-2-(aminomethyl)-5-methyl-2,3-dihydro-1-benzofuran-7-yl]-2-benzyl-N,N-dimethyl-1,2,4-triazol-3-amine
    —— [(2R)-5-methyl-7-pyrazin-2-yl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H15N3O
    [(2R)-5-methyl-7-pyrazin-2-yl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-4-fluoro-7-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H20FNO4
    [(2S)-4-fluoro-7-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— 5-[(2R)-2-(aminomethyl)-5-methyl-2,3-dihydro-1-benzofuran-7-yl]-2-benzyl-N,N-dimethyl-1,2,4-triazol-3-amine —— C21H25N5O
    5-[(2R)-2-(aminomethyl)-5-methyl-2,3-dihydro-1-benzofuran-7-yl]-2-benzyl-N,N-dimethyl-1,2,4-triazol-3-amine
    —— [(2R)-7-(3-fluoro-4-methoxyphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H16FNO2
    [(2R)-7-(3-fluoro-4-methoxyphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-5-methyl-7-pyrazin-2-yl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H15N3O
    [(2S)-5-methyl-7-pyrazin-2-yl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(5-chloropyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H13ClN2O
    [(2R)-7-(5-chloropyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(5-chloropyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H13ClN2O
    [(2S)-7-(5-chloropyridin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-[3-(aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H18N2O
    [(2S)-7-[3-(aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-[3-(aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H18N2O
    [(2R)-7-[3-(aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-5-(5-ethylpyrimidin-2-yl)-7-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H16FN3O
    [(2S)-5-(5-ethylpyrimidin-2-yl)-7-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-4-fluoro-7-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H17FN4O
    [(2S)-4-fluoro-7-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(5-fluoropyridin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H15FN2O
    [(2R)-7-(5-fluoropyridin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-5-(5-ethylpyrimidin-2-yl)-7-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H16FN3O
    [(2R)-5-(5-ethylpyrimidin-2-yl)-7-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(5-fluoropyridin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C15H15FN2O
    [(2S)-7-(5-fluoropyridin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-4-fluoro-7-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H17FN4O
    [(2R)-4-fluoro-7-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(2-chlorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H16ClNO
    [(2S)-7-(2-chlorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(2-chlorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H16ClNO
    [(2R)-7-(2-chlorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(2,4-difluorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H15F2NO
    [(2S)-7-(2,4-difluorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(5-fluoropyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H14FN3O
    [(2S)-7-(5-fluoropyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(2,4-difluorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H15F2NO
    [(2R)-7-(2,4-difluorophenyl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(5-fluoropyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H14FN3O
    [(2R)-7-(5-fluoropyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [4-[(2S)-2-(aminomethyl)-2,3-dihydro-1-benzofuran-7-yl]-3-(hydroxymethyl)phenyl]methanol —— C17H19NO3
    [4-[(2S)-2-(aminomethyl)-2,3-dihydro-1-benzofuran-7-yl]-3-(hydroxymethyl)phenyl]methanol
    —— [4-[(2R)-2-(aminomethyl)-2,3-dihydro-1-benzofuran-7-yl]-3-(hydroxymethyl)phenyl]methanol —— C17H19NO3
    [4-[(2R)-2-(aminomethyl)-2,3-dihydro-1-benzofuran-7-yl]-3-(hydroxymethyl)phenyl]methanol
    —— [(2S)-7-(4-methylpyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H15N3O
    [(2S)-7-(4-methylpyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-5-methyl-7-(2-methyl-5-propylpyrimidin-4-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C18H23N3O
    [(2S)-5-methyl-7-(2-methyl-5-propylpyrimidin-4-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(4-methylpyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C14H15N3O
    [(2R)-7-(4-methylpyrimidin-2-yl)-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-[5-(aminomethyl)pyridin-2-yl]-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H19N3O
    [(2S)-7-[5-(aminomethyl)pyridin-2-yl]-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-[5-(aminomethyl)pyridin-2-yl]-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C16H19N3O
    [(2R)-7-[5-(aminomethyl)pyridin-2-yl]-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2S)-7-(4-ethyl-5-methylpyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C17H21N3O
    [(2S)-7-(4-ethyl-5-methylpyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— [(2R)-7-(4-ethyl-5-methylpyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine —— C17H21N3O
    [(2R)-7-(4-ethyl-5-methylpyrimidin-2-yl)-5-methyl-2,3-dihydro-1-benzofuran-2-yl]methanamine
    —— N-[(2R)-3-(2,3-dichlorophenoxy)-2-hydroxypropyl]-2,3-dihydro-1-benzofuran-5-carboxamide —— C18H17Cl2NO4
    N-[(2R)-3-(2,3-dichlorophenoxy)-2-hydroxypropyl]-2,3-dihydro-1-benzofuran-5-carboxamide
    —— N-(1H-imidazol-2-ylmethyl)-N-methyl-1-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methanamine —— C15H19N3O
    N-(1H-imidazol-2-ylmethyl)-N-methyl-1-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methanamine