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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-N-cyclopropyl-2-methyl-2,3-dihydro-1-benzofuran-5-amine —— C12H15NO
    (2R)-N-cyclopropyl-2-methyl-2,3-dihydro-1-benzofuran-5-amine
    —— (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexanoic acid —— C15H20O3
    (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexanoic acid
    —— (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexanoic acid —— C15H20O3
    (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexanoic acid
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(oxan-4-yl)ethanamine —— C15H21NO2
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(oxan-4-yl)ethanamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(oxan-4-yl)ethanamine —— C15H21NO2
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(oxan-4-yl)ethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-thiophen-2-ylethanamine —— C14H15NOS
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-thiophen-2-ylethanamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-thiophen-2-ylethanamine —— C14H15NOS
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-thiophen-2-ylethanamine
    —— (3R)-3-cyclopentyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine —— C16H23NO
    (3R)-3-cyclopentyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine
    —— (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-3-(furan-2-yl)propan-1-amine —— C15H17NO2
    (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-3-(furan-2-yl)propan-1-amine
    —— (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-3-(furan-2-yl)propan-1-amine —— C15H17NO2
    (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-3-(furan-2-yl)propan-1-amine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-2-ylethanamine —— C15H16N2O
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-2-ylethanamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-4-ylethanamine —— C15H16N2O
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-4-ylethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-4-ylethanamine —— C15H16N2O
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-4-ylethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-phenylethanamine —— C16H17NO
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-phenylethanamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-phenylethanamine —— C16H17NO
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-phenylethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-3-ylethanamine —— C15H16N2O
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-3-ylethanamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-3-ylethanamine —— C15H16N2O
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-3-ylethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-2-ylethanamine —— C15H16N2O
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-pyridin-2-ylethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-N,N-dimethylbutane-1,4-diamine —— C14H22N2O
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-N,N-dimethylbutane-1,4-diamine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-N,N-dimethylbutane-1,4-diamine —— C14H22N2O
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-N,N-dimethylbutane-1,4-diamine
    —— (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexan-1-amine —— C15H23NO
    (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexan-1-amine
    —— (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexan-1-amine —— C15H23NO
    (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)-5-methylhexan-1-amine
    —— (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-4,4-dimethylpentan-1-amine —— C15H23NO
    (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-4,4-dimethylpentan-1-amine
    —— (3S)-3-cyclobutyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine —— C15H21NO
    (3S)-3-cyclobutyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine
    —— (3R)-3-cyclobutyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine —— C15H21NO
    (3R)-3-cyclobutyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(furan-2-yl)ethanamine —— C14H15NO2
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(furan-2-yl)ethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(furan-2-yl)ethanamine —— C14H15NO2
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(furan-2-yl)ethanamine
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutan-1-amine —— C14H21NO
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutan-1-amine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutan-1-amine —— C14H21NO
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutan-1-amine
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-4-methylpentan-1-amine —— C14H21NO
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-4-methylpentan-1-amine
    —— (2R)-2-cyclobutyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine —— C14H19NO
    (2R)-2-cyclobutyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine
    —— (2S)-2-cyclobutyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine —— C14H19NO
    (2S)-2-cyclobutyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine
    —— (3S)-3-cyclopropyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine —— C14H19NO
    (3S)-3-cyclopropyl-3-(2,3-dihydro-1-benzofuran-5-yl)propan-1-amine
    —— N-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-2-(2-nitropyridin-3-yl)oxyacetamide —— C19H21N3O6
    N-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-2-(2-nitropyridin-3-yl)oxyacetamide
    —— 2-methyl-2,3-dihydrobenzofuran-4-carbaldehyd —— C10H10O2
    2-methyl-2,3-dihydrobenzofuran-4-carbaldehyd
    —— (2R)-2-methyl-2,3-dihydro-1-benzofuran-6-carbaldehyde —— C10H10O2
    (2R)-2-methyl-2,3-dihydro-1-benzofuran-6-carbaldehyde
    —— 2-methyl-2,3-dihydrobenzofuran-4-carbaldehyd —— C10H10O2
    2-methyl-2,3-dihydrobenzofuran-4-carbaldehyd
    —— (S)-2-Methyl-2,3-dihydrobenzofuran-6-carbaldehyde —— C10H10O2
    (S)-2-Methyl-2,3-dihydrobenzofuran-6-carbaldehyde
    —— (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)pentan-1-amine —— C13H19NO
    (3S)-3-(2,3-dihydro-1-benzofuran-5-yl)pentan-1-amine
    —— (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)pentan-1-amine —— C13H19NO
    (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)pentan-1-amine
    —— (2S)-2-cyclopropyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine —— C13H17NO
    (2S)-2-cyclopropyl-2-(2,3-dihydro-1-benzofuran-5-yl)ethanamine
    —— 2-[5-(2,3-dihydro-1-benzofuran-5-yl)-2-methyl-1-propan-2-ylpyrrol-3-yl]acetic acid —— C18H21NO3
    2-[5-(2,3-dihydro-1-benzofuran-5-yl)-2-methyl-1-propan-2-ylpyrrol-3-yl]acetic acid
    —— 3-[4-(2,3-dihydro-1-benzofuran-5-yl)-2,6-dimethylpyrimidin-5-yl]propanoic acid —— C17H18N2O3
    3-[4-(2,3-dihydro-1-benzofuran-5-yl)-2,6-dimethylpyrimidin-5-yl]propanoic acid
    —— 2-[1-cyclopropyl-5-(2,3-dihydro-1-benzofuran-5-yl)-2-methylpyrrol-3-yl]acetic acid —— C18H19NO3
    2-[1-cyclopropyl-5-(2,3-dihydro-1-benzofuran-5-yl)-2-methylpyrrol-3-yl]acetic acid
    —— 2-(3-cyano-5-nitro-2-oxopyridin-1-yl)-N-[[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]acetamide —— C20H20N4O6
    2-(3-cyano-5-nitro-2-oxopyridin-1-yl)-N-[[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]acetamide
    —— 2-(3-cyano-5-nitro-2-oxopyridin-1-yl)-N-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]acetamide —— C20H20N4O6
    2-(3-cyano-5-nitro-2-oxopyridin-1-yl)-N-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]acetamide
    —— (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)-1,3-thiazol-2-yl]-N,N-dimethylethane-1,2-diamine —— C15H19N3OS
    (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)-1,3-thiazol-2-yl]-N,N-dimethylethane-1,2-diamine
    —— 3-[(5R)-5-(2,3-dihydro-1-benzofuran-5-yl)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]propanoic acid —— C15H17NO5
    3-[(5R)-5-(2,3-dihydro-1-benzofuran-5-yl)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]propanoic acid
    —— 3-[(5S)-5-(2,3-dihydro-1-benzofuran-5-yl)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]propanoic acid —— C15H17NO5
    3-[(5S)-5-(2,3-dihydro-1-benzofuran-5-yl)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]propanoic acid
    —— 4-(2,3-dihydro-1-benzofuran-5-yl)-2-(dimethylamino)-1,3-thiazole-5-carboxylic acid —— C14H14N2O3S
    4-(2,3-dihydro-1-benzofuran-5-yl)-2-(dimethylamino)-1,3-thiazole-5-carboxylic acid