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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide —— C28H26ClNO4
    2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide
    —— N-[[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine —— C23H15Cl2N3O2S
    N-[[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine
    —— Methyl 2-[2-[2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C22H19N3O4S
    Methyl 2-[2-[2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine —— C22H19ClN4O2
    N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine
    —— [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-morpholin-4-ylsulfonylbenzoate —— C27H22ClNO7S
    [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-morpholin-4-ylsulfonylbenzoate
    —— 3-[(2-Fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H21FO3
    3-[(2-Fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— 2-[2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetonitrile —— C21H18ClNO3
    2-[2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetonitrile
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate —— C22H15ClO4S
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate
    —— 2-(4-Methoxyphenyl)-6,8-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one —— C27H26O5
    2-(4-Methoxyphenyl)-6,8-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one
    —— Methyl 2-[2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H22ClN3O5S
    Methyl 2-[2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]quinazolin-4-amine —— C27H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H22N4O2
    N-[[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate —— C29H28O9
    [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate
    —— 2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[4-(4-methylphenoxy)butoxy]chromen-4-one —— C30H32O6
    2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[4-(4-methylphenoxy)butoxy]chromen-4-one
    —— N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine —— C25H26N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine
    —— N-(4-bromophenyl)-2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide —— C25H19BrClNO4
    N-(4-bromophenyl)-2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide
    —— 2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-3-(2-naphthalen-2-yl-2-oxoethoxy)chromen-4-one —— C31H26O6
    2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-3-(2-naphthalen-2-yl-2-oxoethoxy)chromen-4-one
    —— 2-(4-Methoxyphenyl)-6,8-dimethyl-3-phenylmethoxychromen-4-one —— C25H22O4
    2-(4-Methoxyphenyl)-6,8-dimethyl-3-phenylmethoxychromen-4-one
    —— 2-[2-(2-chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(3,4-dimethylphenyl)acetamide —— C27H24ClNO4
    2-[2-(2-chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(3,4-dimethylphenyl)acetamide
    —— N-[[6-ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C27H23N3O2
    N-[[6-ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— Ethyl 2-[[2-[2-(3,4-dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetyl]amino]-4,5-dimethylthiophene-3-carboxylate —— C30H31NO8S
    Ethyl 2-[[2-[2-(3,4-dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetyl]amino]-4,5-dimethylthiophene-3-carboxylate
    —— [2-(4-Methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-chlorobenzoate —— C25H19ClO5
    [2-(4-Methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-chlorobenzoate
    —— 3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(2-chlorophenyl)-6,8-dimethylchromen-4-one —— C24H17Cl2FO3
    3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(2-chlorophenyl)-6,8-dimethylchromen-4-one
    —— 2-[2-(2-chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide —— C25H26ClNO4
    2-[2-(2-chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide
    —— 3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one —— C26H20Cl2O5
    3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one
    —— 2-(4-Methoxyphenyl)-5,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one —— C26H24O5
    2-(4-Methoxyphenyl)-5,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one
    —— Ethyl 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C24H26O5
    Ethyl 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 2-(4-methoxyphenoxy)acetate —— C25H19ClO6
    [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 2-(4-methoxyphenoxy)acetate
    —— 7-Methyl-2-(4-methylphenyl)-3-(3-phenylpropoxy)chromen-4-one —— C26H24O3
    7-Methyl-2-(4-methylphenyl)-3-(3-phenylpropoxy)chromen-4-one
    —— 2-(4-Tert-butylphenyl)-7-methyl-3-(naphthalen-1-ylmethoxy)chromen-4-one —— C31H28O3
    2-(4-Tert-butylphenyl)-7-methyl-3-(naphthalen-1-ylmethoxy)chromen-4-one
    —— 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-phenylacetamide —— C28H27NO4
    2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-phenylacetamide
    —— Propan-2-yl 2-[7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate —— C22H22O5
    Propan-2-yl 2-[7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate
    —— 7-Methyl-3-[2-oxo-2-(4-phenylphenyl)ethoxy]-2-phenylchromen-4-one —— C30H22O4
    7-Methyl-3-[2-oxo-2-(4-phenylphenyl)ethoxy]-2-phenylchromen-4-one
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 1,2,3,4-tetrahydroacridine-9-carboxylate —— C31H24ClNO4
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 1,2,3,4-tetrahydroacridine-9-carboxylate
    —— 6,8-Dimethyl-2-(4-methylphenyl)-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one —— C30H24O4
    6,8-Dimethyl-2-(4-methylphenyl)-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one
    —— 2-[2-(4-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2,5-dichlorophenyl)acetamide —— C24H16Cl3NO4
    2-[2-(4-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2,5-dichlorophenyl)acetamide
    —— methyl (2S)-2-(7-methyl-4-oxo-2-phenylchromen-3-yl)oxypropanoate —— C20H18O5
    methyl (2S)-2-(7-methyl-4-oxo-2-phenylchromen-3-yl)oxypropanoate
    —— [2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3-(4-tert-butylphenoxy)propanoate —— C30H30O6
    [2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3-(4-tert-butylphenoxy)propanoate
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3-chlorobenzoate —— C25H19ClO6
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3-chlorobenzoate
    —— 7-Methyl-2-(4-methylphenyl)-3-phenacyloxychromen-4-one —— C25H20O4
    7-Methyl-2-(4-methylphenyl)-3-phenacyloxychromen-4-one
    —— 2-(4-chlorophenyl)-7-methyl-3-[(2S)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one —— C25H19ClO4
    2-(4-chlorophenyl)-7-methyl-3-[(2S)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one
    —— [2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2-(4-chlorophenoxy)acetate —— C25H19ClO6
    [2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2-(4-chlorophenoxy)acetate
    —— 2-(2-Chlorophenyl)-7-methyl-3-[2-(4-methylphenyl)-2-oxoethoxy]chromen-4-one —— C25H19ClO4
    2-(2-Chlorophenyl)-7-methyl-3-[2-(4-methylphenyl)-2-oxoethoxy]chromen-4-one
    —— 2-(2-Chlorophenyl)-3-hydroxy-7-methylchromen-4-one —— C16H11ClO3
    2-(2-Chlorophenyl)-3-hydroxy-7-methylchromen-4-one
    —— [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] pyridine-3-carboxylate —— C22H14ClNO4
    [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] pyridine-3-carboxylate
    —— 3-[(3-Chlorophenyl)methoxy]-6,8-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H21ClO3
    3-[(3-Chlorophenyl)methoxy]-6,8-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— 6,8-Dimethyl-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one —— C25H22O3
    6,8-Dimethyl-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one
    —— 2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide —— C25H26ClNO4
    2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide
    —— [2-(2-Chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate —— C22H15ClO4S
    [2-(2-Chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate
    —— 3-Methoxy-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C18H16O4
    3-Methoxy-2-(4-methoxyphenyl)-7-methylchromen-4-one