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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (R)-(4-ethylsulfanylphenyl)-thiophen-3-ylmethanol —— C13H14OS2
    (R)-(4-ethylsulfanylphenyl)-thiophen-3-ylmethanol
    —— (S)-(1-methylpyrrol-2-yl)-(2-methylsulfanylphenyl)methanol —— C13H15NOS
    (S)-(1-methylpyrrol-2-yl)-(2-methylsulfanylphenyl)methanol
    —— (S)-furan-3-yl-(4-methylsulfanylphenyl)methanol —— C12H12O2S
    (S)-furan-3-yl-(4-methylsulfanylphenyl)methanol
    —— (S)-(4-ethylsulfanylphenyl)-thiophen-3-ylmethanol —— C13H14OS2
    (S)-(4-ethylsulfanylphenyl)-thiophen-3-ylmethanol
    —— (R)-(2-methylsulfanylphenyl)-pyridin-2-ylmethanol —— C13H13NOS
    (R)-(2-methylsulfanylphenyl)-pyridin-2-ylmethanol
    —— (S)-(1-methylpyrrol-2-yl)-(4-methylsulfanylphenyl)methanol —— C13H15NOS
    (S)-(1-methylpyrrol-2-yl)-(4-methylsulfanylphenyl)methanol
    —— (R)-(4-ethylsulfanylphenyl)-(1-methylpyrrol-2-yl)methanol —— C14H17NOS
    (R)-(4-ethylsulfanylphenyl)-(1-methylpyrrol-2-yl)methanol
    —— (R)-furan-2-yl-(4-methylsulfanylphenyl)methanol —— C12H12O2S
    (R)-furan-2-yl-(4-methylsulfanylphenyl)methanol
    —— (R)-furan-3-yl-(2-methylsulfanylphenyl)methanol —— C12H12O2S
    (R)-furan-3-yl-(2-methylsulfanylphenyl)methanol
    —— (R)-(4-ethylsulfanylphenyl)-(5-methylfuran-2-yl)methanol —— C14H16O2S
    (R)-(4-ethylsulfanylphenyl)-(5-methylfuran-2-yl)methanol
    —— (S)-(5-methylfuran-2-yl)-(2-methylsulfanylphenyl)methanol —— C13H14O2S
    (S)-(5-methylfuran-2-yl)-(2-methylsulfanylphenyl)methanol
    —— (S)-furan-2-yl-(4-methylsulfanylphenyl)methanol —— C12H12O2S
    (S)-furan-2-yl-(4-methylsulfanylphenyl)methanol
    —— (S)-(4-ethylsulfanylphenyl)-(furan-2-yl)methanol —— C13H14O2S
    (S)-(4-ethylsulfanylphenyl)-(furan-2-yl)methanol
    —— (R)-(5-methylfuran-2-yl)-(2-methylsulfanylphenyl)methanol —— C13H14O2S
    (R)-(5-methylfuran-2-yl)-(2-methylsulfanylphenyl)methanol
    —— (R)-furan-3-yl-(4-methylsulfanylphenyl)methanol —— C12H12O2S
    (R)-furan-3-yl-(4-methylsulfanylphenyl)methanol
    —— (R)-(4-ethylsulfanylphenyl)-(furan-3-yl)methanol —— C13H14O2S
    (R)-(4-ethylsulfanylphenyl)-(furan-3-yl)methanol
    —— (R)-(4-(methylthio)phenyl)(pyridin-2-yl)methanol —— C13H13NOS
    (R)-(4-(methylthio)phenyl)(pyridin-2-yl)methanol
    —— (S)-(4-ethylsulfanylphenyl)-(5-methylfuran-2-yl)methanol —— C14H16O2S
    (S)-(4-ethylsulfanylphenyl)-(5-methylfuran-2-yl)methanol
    —— (S)-(4-ethylsulfanylphenyl)-(furan-3-yl)methanol —— C13H14O2S
    (S)-(4-ethylsulfanylphenyl)-(furan-3-yl)methanol
    —— (S)-furan-2-yl-(2-methylsulfanylphenyl)methanol —— C12H12O2S
    (S)-furan-2-yl-(2-methylsulfanylphenyl)methanol
    —— (S)-furan-3-yl-(2-methylsulfanylphenyl)methanol —— C12H12O2S
    (S)-furan-3-yl-(2-methylsulfanylphenyl)methanol
    —— (R)-(4-ethylsulfanylphenyl)-pyridin-2-ylmethanol —— C14H15NOS
    (R)-(4-ethylsulfanylphenyl)-pyridin-2-ylmethanol
    —— (S)-(4-(methylthio)phenyl)(pyridin-2-yl)methanol —— C13H13NOS
    (S)-(4-(methylthio)phenyl)(pyridin-2-yl)methanol
    —— (S)-(2-methylsulfanylphenyl)-pyridin-2-ylmethanol —— C13H13NOS
    (S)-(2-methylsulfanylphenyl)-pyridin-2-ylmethanol
    —— (R)-furan-2-yl-(2-methylsulfanylphenyl)methanol —— C12H12O2S
    (R)-furan-2-yl-(2-methylsulfanylphenyl)methanol
    —— (R)-(4-ethylsulfanylphenyl)-(furan-2-yl)methanol —— C13H14O2S
    (R)-(4-ethylsulfanylphenyl)-(furan-2-yl)methanol
    —— (S)-(4-ethylsulfanylphenyl)-pyridin-2-ylmethanol —— C14H15NOS
    (S)-(4-ethylsulfanylphenyl)-pyridin-2-ylmethanol
    —— (1S)-3-cyclopropyloxy-N-methyl-5-methylsulfanylcyclohexa-2,4-dien-1-amine —— C11H17NOS
    (1S)-3-cyclopropyloxy-N-methyl-5-methylsulfanylcyclohexa-2,4-dien-1-amine
    —— (S)-(5-methylfuran-2-yl)-(4-methylsulfanylphenyl)methanol —— C13H14O2S
    (S)-(5-methylfuran-2-yl)-(4-methylsulfanylphenyl)methanol
    —— (R)-(5-methylfuran-2-yl)-(4-methylsulfanylphenyl)methanol —— C13H14O2S
    (R)-(5-methylfuran-2-yl)-(4-methylsulfanylphenyl)methanol
    —— (5S)-3-cyclopropyloxy-5-ethyl-1-methylsulfanylcyclohexa-1,3-diene —— C12H18OS
    (5S)-3-cyclopropyloxy-5-ethyl-1-methylsulfanylcyclohexa-1,3-diene
    —— (1R)-3-cyclopropyloxy-N-methyl-5-methylsulfanylcyclohexa-2,4-dien-1-amine —— C11H17NOS
    (1R)-3-cyclopropyloxy-N-methyl-5-methylsulfanylcyclohexa-2,4-dien-1-amine
    —— (5R)-3-cyclopropyloxy-5-ethyl-1-methylsulfanylcyclohexa-1,3-diene —— C12H18OS
    (5R)-3-cyclopropyloxy-5-ethyl-1-methylsulfanylcyclohexa-1,3-diene
    —— 2-(2-fluorophenyl)sulfanylethyl (E)-2-cyano-3-[2,5-dimethyl-1-(3-methylbutyl)pyrrol-3-yl]prop-2-enoate —— C23H27FN2O2S
    2-(2-fluorophenyl)sulfanylethyl (E)-2-cyano-3-[2,5-dimethyl-1-(3-methylbutyl)pyrrol-3-yl]prop-2-enoate
    —— 1-methyl-N-[2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]pyrrole-2-carboxamide —— C17H16N4O3S
    1-methyl-N-[2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]pyrrole-2-carboxamide
    —— 2-[(3-Bromophenyl)methylsulfanyl]-5-(4-methylphenyl)-1,3,4-oxadiazole —— C16H13BrN2OS
    2-[(3-Bromophenyl)methylsulfanyl]-5-(4-methylphenyl)-1,3,4-oxadiazole
    —— N-cycloheptyl-2-[(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide —— C12H19N3OS3
    N-cycloheptyl-2-[(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H21N3O4S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H21N3O4S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-(4-methylphenyl)-4-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanylmethyl]-1,3-thiazol-2-amine —— C17H19N5S2
    N-(4-methylphenyl)-4-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanylmethyl]-1,3-thiazol-2-amine
    —— dimethyl (2E,7R)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate —— C26H24N2O5S3
    dimethyl (2E,7R)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate
    —— (2R,5E)-2-heptyl-5-[(4-methylsulfanylphenyl)methylidene]cyclopentan-1-one —— C20H28OS
    (2R,5E)-2-heptyl-5-[(4-methylsulfanylphenyl)methylidene]cyclopentan-1-one
    —— dimethyl (2E,7S)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate —— C26H24N2O5S3
    dimethyl (2E,7S)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate
    —— diethyl (2E,7S)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate —— C28H28N2O5S3
    diethyl (2E,7S)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate
    —— diethyl (2E,7R)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate —— C28H28N2O5S3
    diethyl (2E,7R)-5-amino-7-(4-methylsulfanylphenyl)-2-[(4-methylsulfanylphenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarboxylate
    —— (2S,5E)-2-heptyl-5-[(4-methylsulfanylphenyl)methylidene]cyclopentan-1-one —— C20H28OS
    (2S,5E)-2-heptyl-5-[(4-methylsulfanylphenyl)methylidene]cyclopentan-1-one
    —— methyl (4S)-2-methyl-5-oxo-4-(5-phenylsulfanylfuran-2-yl)-3,4-dihydroindeno[1,2-b]pyridine-3-carboxylate —— C25H19NO4S
    methyl (4S)-2-methyl-5-oxo-4-(5-phenylsulfanylfuran-2-yl)-3,4-dihydroindeno[1,2-b]pyridine-3-carboxylate
    —— methyl 2-[[5-[(2Z)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetate —— C10H11N5O3S
    methyl 2-[[5-[(2Z)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetate
    —— methyl 2-[[5-[(2Z)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetate —— C12H12BrN5O2S
    methyl 2-[[5-[(2Z)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetate
    —— 2-(4-chlorophenyl)sulfanyl-N-[(1R)-1-(3,4-dimethylphenyl)ethyl]acetamide —— C18H20ClNOS
    2-(4-chlorophenyl)sulfanyl-N-[(1R)-1-(3,4-dimethylphenyl)ethyl]acetamide