摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-Ethylsulfanyl-5-[(3-fluorophenyl)methyl]-3,6-dimethylpyrimidin-4-one —— C15H17FN2OS
    2-Ethylsulfanyl-5-[(3-fluorophenyl)methyl]-3,6-dimethylpyrimidin-4-one
    —— 2-[(3,4-difluorobenzyl)sulfanyl]-3,6-dimethyl-5-(2-methylbenzyl)-4(3H)-pyrimidinone —— C21H20F2N2OS
    2-[(3,4-difluorobenzyl)sulfanyl]-3,6-dimethyl-5-(2-methylbenzyl)-4(3H)-pyrimidinone
    —— [(1S,2R)-1-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-methylbutyl]azanium —— C14H20N3OS+
    [(1S,2R)-1-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-methylbutyl]azanium
    —— 2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide —— C21H24N4OS2
    2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide
    —— 3,3-Dimethyl-6-methylsulfanyl-8-morpholin-4-yl-1,4-dihydrothiopyrano[3,4-c]pyridin-7-ium-5-carbonitrile —— C16H22N3OS2+
    3,3-Dimethyl-6-methylsulfanyl-8-morpholin-4-yl-1,4-dihydrothiopyrano[3,4-c]pyridin-7-ium-5-carbonitrile
    —— [(6S)-4-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]-1,4-oxazepan-6-yl]methanol —— C18H24N4O2S
    [(6S)-4-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]-1,4-oxazepan-6-yl]methanol
    —— [(6R)-4-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]-1,4-oxazepan-6-yl]methanol —— C18H24N4O2S
    [(6R)-4-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]-1,4-oxazepan-6-yl]methanol
    —— 2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanyl-N-(thiophen-2-ylmethyl)acetamide —— C16H17N3OS2
    2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanyl-N-(thiophen-2-ylmethyl)acetamide
    —— 2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5,6-trimethylpyridine-3-carbonitrile —— C16H14ClFN2S
    2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5,6-trimethylpyridine-3-carbonitrile
    —— ethyl 5-[(2R)-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylpropanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C21H25N3O3S
    ethyl 5-[(2R)-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylpropanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— 2-[(1S)-1-(2-chlorophenyl)ethyl]sulfanyl-4,5,6-trimethylpyridine-3-carbonitrile —— C17H17ClN2S
    2-[(1S)-1-(2-chlorophenyl)ethyl]sulfanyl-4,5,6-trimethylpyridine-3-carbonitrile
    —— N-[(2S)-butan-2-yl]-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylacetamide —— C15H21N3OS
    N-[(2S)-butan-2-yl]-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylacetamide
    —— 2-[(4-Fluorophenyl)methylsulfanyl]-4,5,6-trimethylpyridine-3-carbonitrile —— C16H15FN2S
    2-[(4-Fluorophenyl)methylsulfanyl]-4,5,6-trimethylpyridine-3-carbonitrile
    —— N-(1-cyanocyclopentyl)-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylacetamide —— C17H20N4OS
    N-(1-cyanocyclopentyl)-2-(3-cyano-4,5,6-trimethylpyridin-2-yl)sulfanylacetamide
    —— N-(2-benzylsulfanylethyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide —— C14H17N3OS3
    N-(2-benzylsulfanylethyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide
    —— N-(2-benzylsulfanylethyl)-2-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C20H21N3O2S2
    N-(2-benzylsulfanylethyl)-2-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)-2-[[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C22H23N3O3S
    N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)-2-[[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[5-[2-(4,6-Diaminopyrimidin-2-yl)sulfanylacetyl]thiophen-2-yl]-1-morpholin-4-ylethanone —— C16H19N5O3S2
    2-[5-[2-(4,6-Diaminopyrimidin-2-yl)sulfanylacetyl]thiophen-2-yl]-1-morpholin-4-ylethanone
    —— N-(2-benzylsulfanylethyl)-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C19H22N4O2S2
    N-(2-benzylsulfanylethyl)-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-[(4-amino-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)acetamide —— C19H21N5O2S2
    2-[(4-amino-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)acetamide
    —— N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C21H21N3O3S
    N-(cyclohexen-1-yl)-N-(furan-2-ylmethyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— [2-(Cyclohexylamino)-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C18H28N4O3S2
    [2-(Cyclohexylamino)-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— [(2S)-1-amino-1-oxopropan-2-yl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C13H20N4O3S2
    [(2S)-1-amino-1-oxopropan-2-yl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— (3,5-Dimethyl-1,2-oxazol-4-yl)methyl 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C16H22N4O3S2
    (3,5-Dimethyl-1,2-oxazol-4-yl)methyl 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— 2-butylsulfanyl-4-N-[(3S)-oxolan-3-yl]pyrimidine-4,6-diamine —— C12H20N4OS
    2-butylsulfanyl-4-N-[(3S)-oxolan-3-yl]pyrimidine-4,6-diamine
    —— [(1R)-1-cyanoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C13H18N4O2S2
    [(1R)-1-cyanoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— (2-Oxo-2-pyrrolidin-1-ylethyl) 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C16H24N4O3S2
    (2-Oxo-2-pyrrolidin-1-ylethyl) 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— [2-Oxo-2-(pentan-3-ylamino)ethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C17H28N4O3S2
    [2-Oxo-2-(pentan-3-ylamino)ethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C17H28N4O3S2
    [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— [2-oxo-2-(1H-pyrrol-2-yl)ethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C16H20N4O3S2
    [2-oxo-2-(1H-pyrrol-2-yl)ethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— 2-butylsulfanyl-4-N-[(3R)-oxolan-3-yl]pyrimidine-4,6-diamine —— C12H20N4OS
    2-butylsulfanyl-4-N-[(3R)-oxolan-3-yl]pyrimidine-4,6-diamine
    —— [2-[2-Cyanoethyl(methyl)amino]-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C16H23N5O3S2
    [2-[2-Cyanoethyl(methyl)amino]-2-oxoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— [(1S)-1-cyanoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate —— C13H18N4O2S2
    [(1S)-1-cyanoethyl] 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
    —— 2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1R,2S)-2-methylcyclohexyl]acetamide —— C14H24N4O2S2
    2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1R,2S)-2-methylcyclohexyl]acetamide
    —— 2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)acetamide —— C11H20N4O2S2
    2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)acetamide
    —— (3S)-1-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]piperidin-3-ol —— C17H22N4OS
    (3S)-1-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]piperidin-3-ol
    —— (3R)-1-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]piperidin-3-ol —— C17H22N4OS
    (3R)-1-[6-amino-2-[(2-methylphenyl)methylsulfanyl]pyrimidin-4-yl]piperidin-3-ol
    —— N-[4-(2,5-dimethylphenyl)sulfanylphenyl]-2-(2-fluorophenyl)sulfanylacetamide —— C22H20FNOS2
    N-[4-(2,5-dimethylphenyl)sulfanylphenyl]-2-(2-fluorophenyl)sulfanylacetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[2-[[2-(2-fluorophenyl)sulfanylacetyl]amino]ethyl]acetamide —— C18H18F2N2O2S2
    2-(2-fluorophenyl)sulfanyl-N-[2-[[2-(2-fluorophenyl)sulfanylacetyl]amino]ethyl]acetamide
    —— 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(1E)-1-(4-methylphenyl)ethylidene]acetohydrazide —— C17H20N4OS
    2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(1E)-1-(4-methylphenyl)ethylidene]acetohydrazide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]acetamide —— C14H21N3O4S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]acetamide
    —— 1-(2-methylsulfanylpyrimidin-4-yl)-N-[(1S)-1-phenyl-2-pyrazol-1-ylethyl]piperidin-4-amine —— C21H26N6S
    1-(2-methylsulfanylpyrimidin-4-yl)-N-[(1S)-1-phenyl-2-pyrazol-1-ylethyl]piperidin-4-amine
    —— [(1S)-1-[5-[2-(diethylamino)-2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]ethyl]azanium —— C10H19N4O2S+
    [(1S)-1-[5-[2-(diethylamino)-2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]ethyl]azanium
    —— tert-butyl N-[(1S,2R)-2-methyl-1-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)butyl]carbamate —— C13H23N3O3S
    tert-butyl N-[(1S,2R)-2-methyl-1-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)butyl]carbamate
    —— N,N-diethyl-2-[5-[(3-fluorophenyl)methyl]-1,4-dimethyl-6-oxopyrimidin-2-yl]sulfanylacetamide —— C19H24FN3O2S
    N,N-diethyl-2-[5-[(3-fluorophenyl)methyl]-1,4-dimethyl-6-oxopyrimidin-2-yl]sulfanylacetamide
    —— tert-butyl N-[(1S,2R)-1-[5-[2-(diethylamino)-2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]-2-methylbutyl]carbamate —— C18H32N4O4S
    tert-butyl N-[(1S,2R)-1-[5-[2-(diethylamino)-2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]-2-methylbutyl]carbamate
    —— 1-(2-methylsulfanylpyrimidin-4-yl)-N-[(1R)-1-phenyl-2-pyrazol-1-ylethyl]piperidin-4-amine —— C21H26N6S
    1-(2-methylsulfanylpyrimidin-4-yl)-N-[(1R)-1-phenyl-2-pyrazol-1-ylethyl]piperidin-4-amine
    —— (3S)-3-[[(6-amino-2-butylsulfanylpyrimidin-4-yl)amino]methyl]pyrrolidin-3-ol —— C13H23N5OS
    (3S)-3-[[(6-amino-2-butylsulfanylpyrimidin-4-yl)amino]methyl]pyrrolidin-3-ol
    —— (3R)-3-[[(6-amino-2-butylsulfanylpyrimidin-4-yl)amino]methyl]pyrrolidin-3-ol —— C13H23N5OS
    (3R)-3-[[(6-amino-2-butylsulfanylpyrimidin-4-yl)amino]methyl]pyrrolidin-3-ol
    —— 2-butylsulfanyl-6-[(3R)-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-amine —— C14H24N4OS
    2-butylsulfanyl-6-[(3R)-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-amine