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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[(2R)-2-methylpyrrolidin-2-yl]-5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazole —— C9H14N4S
    2-[(2R)-2-methylpyrrolidin-2-yl]-5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazole
    —— N-[(1S)-1-(2,3-dihydro-1-benzothiophen-6-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1S)-1-(2,3-dihydro-1-benzothiophen-6-yl)ethyl]-N-methylhydroxylamine
    —— 2-[(3S)-piperidin-3-yl]-5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazole —— C9H14N4S
    2-[(3S)-piperidin-3-yl]-5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazole
    —— N-methyl-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]methyl]hydroxylamine —— C11H15NOS
    N-methyl-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]methyl]hydroxylamine
    —— N-methyl-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]methyl]hydroxylamine —— C11H15NOS
    N-methyl-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]methyl]hydroxylamine
    —— N-[(1R)-1-(2,3-dihydro-1-benzothiophen-6-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1R)-1-(2,3-dihydro-1-benzothiophen-6-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1R)-1-(2,3-dihydro-1-benzothiophen-7-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1R)-1-(2,3-dihydro-1-benzothiophen-7-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1R)-1-(2,3-dihydro-1-benzothiophen-5-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1R)-1-(2,3-dihydro-1-benzothiophen-5-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1S)-1-(2,3-dihydro-1-benzothiophen-5-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1S)-1-(2,3-dihydro-1-benzothiophen-5-yl)ethyl]-N-methylhydroxylamine
    —— 2-methylsulfanyl-5-[(3R)-piperidin-3-yl]pyrimidine —— C10H15N3S
    2-methylsulfanyl-5-[(3R)-piperidin-3-yl]pyrimidine
    —— N-[(1S)-1-(2,3-dihydro-1-benzothiophen-4-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1S)-1-(2,3-dihydro-1-benzothiophen-4-yl)ethyl]-N-methylhydroxylamine
    —— 4-methyl-2-methylsulfanyl-5-[(3R)-pyrrolidin-3-yl]pyrimidine —— C10H15N3S
    4-methyl-2-methylsulfanyl-5-[(3R)-pyrrolidin-3-yl]pyrimidine
    —— N-[(1R)-1-(2,3-dihydro-1-benzothiophen-4-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1R)-1-(2,3-dihydro-1-benzothiophen-4-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1S)-1-(2,3-dihydro-1-benzothiophen-7-yl)ethyl]-N-methylhydroxylamine —— C11H15NOS
    N-[(1S)-1-(2,3-dihydro-1-benzothiophen-7-yl)ethyl]-N-methylhydroxylamine
    —— (2R)-2-(2,3-dihydro-1-benzothiophen-6-yl)propanoic acid —— C11H12O2S
    (2R)-2-(2,3-dihydro-1-benzothiophen-6-yl)propanoic acid
    —— (2S)-2-(2,3-dihydro-1-benzothiophen-7-yl)propanoic acid —— C11H12O2S
    (2S)-2-(2,3-dihydro-1-benzothiophen-7-yl)propanoic acid
    —— (2R)-2-(2,3-dihydro-1-benzothiophen-4-yl)propanoic acid —— C11H12O2S
    (2R)-2-(2,3-dihydro-1-benzothiophen-4-yl)propanoic acid
    —— 5-[(1R)-1-aminopropyl]-1-benzothiophen-3-one —— C11H13NOS
    5-[(1R)-1-aminopropyl]-1-benzothiophen-3-one
    —— (2R)-2-(2,3-dihydro-1-benzothiophen-7-yl)propanoic acid —— C11H12O2S
    (2R)-2-(2,3-dihydro-1-benzothiophen-7-yl)propanoic acid
    —— (2S)-2-(2,3-dihydro-1-benzothiophen-5-yl)propanoic acid —— C11H12O2S
    (2S)-2-(2,3-dihydro-1-benzothiophen-5-yl)propanoic acid
    —— (2S)-2-(2,3-dihydro-1-benzothiophen-6-yl)propanoic acid —— C11H12O2S
    (2S)-2-(2,3-dihydro-1-benzothiophen-6-yl)propanoic acid
    —— 5-[(2R)-2-aminopropyl]-1-benzothiophen-3-one —— C11H13NOS
    5-[(2R)-2-aminopropyl]-1-benzothiophen-3-one
    —— 5-[(2S)-2-aminopropyl]-1-benzothiophen-3-one —— C11H13NOS
    5-[(2S)-2-aminopropyl]-1-benzothiophen-3-one
    —— 5-[(1S)-1-aminopropyl]-1-benzothiophen-3-one —— C11H13NOS
    5-[(1S)-1-aminopropyl]-1-benzothiophen-3-one
    —— (1R)-2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanol —— C7H12N2OS2
    (1R)-2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanol
    —— (1S)-2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanol —— C7H12N2OS2
    (1S)-2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanol
    —— (2S,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde —— C7H7NO2S2
    (2S,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde
    —— (2R,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde —— C7H7NO2S2
    (2R,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde
    —— 1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)-2-hydroxyethanone —— C7H9N3O2S
    1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)-2-hydroxyethanone
    —— N-[(1S)-1-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethyl]-N-methylhydroxylamine —— C7H12N4OS
    N-[(1S)-1-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1S)-1-(5,6-dihydro-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)ethyl]-N-methylhydroxylamine —— C7H12N4OS
    N-[(1S)-1-(5,6-dihydro-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)ethyl]-N-methylhydroxylamine
    —— 2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanone —— C7H10N4OS
    2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanone
    —— N-[(1S)-1-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethyl]-N-methylhydroxylamine —— C8H13N3OS
    N-[(1S)-1-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethyl]-N-methylhydroxylamine
    —— (1S)-2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanol —— C7H12N4OS
    (1S)-2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanol
    —— (2S,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde —— C7H7NO2S2
    (2S,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde
    —— (2S,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde —— C7H7NO2S2
    (2S,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde
    —— N-[(1R)-1-(5,6-dihydro-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)ethyl]-N-methylhydroxylamine —— C7H12N4OS
    N-[(1R)-1-(5,6-dihydro-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)ethyl]-N-methylhydroxylamine
    —— (2R,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde —— C7H7NO2S2
    (2R,3S)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde
    —— 2-amino-1-(5-amino-1-methyl-3-methylsulfanylpyrrol-2-yl)ethanone —— C8H13N3OS
    2-amino-1-(5-amino-1-methyl-3-methylsulfanylpyrrol-2-yl)ethanone
    —— 1-(5-amino-3-methylsulfanylthiophen-2-yl)-2-hydroxyethanone —— C7H9NO2S2
    1-(5-amino-3-methylsulfanylthiophen-2-yl)-2-hydroxyethanone
    —— 1-(5-amino-1-methyl-3-methylsulfanylpyrrol-2-yl)-2-hydroxyethanone —— C8H12N2O2S
    1-(5-amino-1-methyl-3-methylsulfanylpyrrol-2-yl)-2-hydroxyethanone
    —— 2-(2,3-dihydrothieno[2,3-b]thiophen-5-yl)acetic acid —— C8H8O2S2
    2-(2,3-dihydrothieno[2,3-b]thiophen-5-yl)acetic acid
    —— (2R,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde —— C7H7NO2S2
    (2R,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,2-b]thiophene-5-carbaldehyde
    —— N-[(1R)-1-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethyl]-N-methylhydroxylamine —— C8H13N3OS
    N-[(1R)-1-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethyl]-N-methylhydroxylamine
    —— N-[(1R)-1-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethyl]-N-methylhydroxylamine —— C7H12N4OS
    N-[(1R)-1-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethyl]-N-methylhydroxylamine
    —— N-methyl-N-[(1R)-1-(3-methylsulfanylphenyl)ethyl]hydroxylamine —— C10H15NOS
    N-methyl-N-[(1R)-1-(3-methylsulfanylphenyl)ethyl]hydroxylamine
    —— 2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanone —— C7H10N2OS2
    2-amino-1-(5-amino-3-methylsulfanylthiophen-2-yl)ethanone
    —— (1R)-2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanol —— C7H12N4OS
    (1R)-2-amino-1-(6-amino-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)ethanol
    —— (2R,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde —— C7H7NO2S2
    (2R,3R)-2-amino-3-hydroxy-2,3-dihydrothieno[3,4-b]thiophene-6-carbaldehyde
    —— N'-[2-(4-methylphenyl)sulfanylacetyl]-5-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)pentanehydrazide —— C17H21N3O3S3
    N'-[2-(4-methylphenyl)sulfanylacetyl]-5-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)pentanehydrazide