摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(5-Chloropyrimidin-2-yl)sulfanyl-4,5-dimethyl-1,3-oxazole —— C9H8ClN3OS
    2-(5-Chloropyrimidin-2-yl)sulfanyl-4,5-dimethyl-1,3-oxazole
    —— (3R)-N'-ethyl-3-(phenylsulfanylmethyl)pyrrolidine-1-carboximidamide —— C14H21N3S
    (3R)-N'-ethyl-3-(phenylsulfanylmethyl)pyrrolidine-1-carboximidamide
    —— (3S)-N'-ethyl-3-(phenylsulfanylmethyl)pyrrolidine-1-carboximidamide —— C14H21N3S
    (3S)-N'-ethyl-3-(phenylsulfanylmethyl)pyrrolidine-1-carboximidamide
    —— (2R)-2-ethanimidoyl-4-[[4-(2-methylphenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]-3-oxobutanenitrile —— C15H14N4OS3
    (2R)-2-ethanimidoyl-4-[[4-(2-methylphenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]-3-oxobutanenitrile
    —— (3S)-3-(2-hydroxyphenyl)sulfanyl-1-(1-methylpyrazol-4-yl)piperidin-2-one —— C15H17N3O2S
    (3S)-3-(2-hydroxyphenyl)sulfanyl-1-(1-methylpyrazol-4-yl)piperidin-2-one
    —— 3-[[(2S,5S)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-1H-1,2,4-triazol-5-amine —— C14H20N6OS
    3-[[(2S,5S)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-1H-1,2,4-triazol-5-amine
    —— 3-[(1S)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-4-amine —— C11H17N5OS
    3-[(1S)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-4-amine
    —— 3-[(1R)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-4-amine —— C11H17N5OS
    3-[(1R)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-4-amine
    —— (3R)-3-(2-hydroxyphenyl)sulfanyl-1-(1-methylpyrazol-4-yl)piperidin-2-one —— C15H17N3O2S
    (3R)-3-(2-hydroxyphenyl)sulfanyl-1-(1-methylpyrazol-4-yl)piperidin-2-one
    —— 5-tert-butyl-2-[(1S)-1-[5-(trifluoromethyl)pyridin-2-yl]sulfanylethyl]-1,3-oxazole —— C15H17F3N2OS
    5-tert-butyl-2-[(1S)-1-[5-(trifluoromethyl)pyridin-2-yl]sulfanylethyl]-1,3-oxazole
    —— 2-[(1R)-1-(5-ethyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanylphenol —— C12H14N2O2S
    2-[(1R)-1-(5-ethyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanylphenol
    —— 5-tert-butyl-2-[(1R)-1-[5-(trifluoromethyl)pyridin-2-yl]sulfanylethyl]-1,3-oxazole —— C15H17F3N2OS
    5-tert-butyl-2-[(1R)-1-[5-(trifluoromethyl)pyridin-2-yl]sulfanylethyl]-1,3-oxazole
    —— 2-[(1S)-1-(5-ethyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanylphenol —— C12H14N2O2S
    2-[(1S)-1-(5-ethyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanylphenol
    —— 2-[(1S)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-5-pyridin-3-yl-1,3,4-oxadiazole —— C16H18N4O2S
    2-[(1S)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-5-pyridin-3-yl-1,3,4-oxadiazole
    —— 2-[(1R)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-5-pyridin-3-yl-1,3,4-oxadiazole —— C16H18N4O2S
    2-[(1R)-1-(5-tert-butyl-1,3-oxazol-2-yl)ethyl]sulfanyl-5-pyridin-3-yl-1,3,4-oxadiazole
    —— 2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide —— C14H19N5OS2
    2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide
    —— 2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide —— C14H19N5OS2
    2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide
    —— (2S)-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-2-phenylacetate —— C13H11N2O3S-
    (2S)-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-2-phenylacetate
    —— (2S)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]cyclohexan-1-one —— C14H13FN2OS3
    (2S)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]cyclohexan-1-one
    —— (2S)-N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C17H19FN4OS3
    (2S)-N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— 3-[[4-(4-Fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanenitrile —— C11H8FN3S3
    3-[[4-(4-Fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanenitrile
    —— N-[(1R)-1-cyano-1-cyclopropylethyl]-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C16H15FN4OS3
    N-[(1R)-1-cyano-1-cyclopropylethyl]-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[4-(4-Fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]-1-thiophen-2-ylethanone —— C14H9FN2OS4
    2-[[4-(4-Fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]-1-thiophen-2-ylethanone
    —— N-(1-cyanocyclopentyl)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C16H15FN4OS3
    N-(1-cyanocyclopentyl)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— methyl (2R)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanoate —— C12H11FN2O2S3
    methyl (2R)-2-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]propanoate
    —— (2S)-N-(4,5-dihydro-1,3-thiazol-2-yl)-2-phenylsulfanylpropanamide —— C12H14N2OS2
    (2S)-N-(4,5-dihydro-1,3-thiazol-2-yl)-2-phenylsulfanylpropanamide
    —— (3R)-3-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]oxolan-2-one —— C12H9FN2O2S3
    (3R)-3-[[4-(4-fluorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]oxolan-2-one
    —— 2-[[6-(2-aminophenyl)-5-oxo-4H-1,2,4-triazin-3-yl]sulfanyl]-N-cycloheptylacetamide —— C18H23N5O2S
    2-[[6-(2-aminophenyl)-5-oxo-4H-1,2,4-triazin-3-yl]sulfanyl]-N-cycloheptylacetamide
    —— 2-[[6-(2-aminophenyl)-5-oxo-4H-1,2,4-triazin-3-yl]sulfanyl]-N-[(1S)-1-(3-chlorophenyl)ethyl]acetamide —— C19H18ClN5O2S
    2-[[6-(2-aminophenyl)-5-oxo-4H-1,2,4-triazin-3-yl]sulfanyl]-N-[(1S)-1-(3-chlorophenyl)ethyl]acetamide
    —— 6-(2-aminophenyl)-3-[2-oxo-2-(5-phenyl-3,4-dihydropyrazol-2-yl)ethyl]sulfanyl-4H-1,2,4-triazin-5-one —— C20H18N6O2S
    6-(2-aminophenyl)-3-[2-oxo-2-(5-phenyl-3,4-dihydropyrazol-2-yl)ethyl]sulfanyl-4H-1,2,4-triazin-5-one
    —— 6-(2-aminophenyl)-3-[2-oxo-2-(2-oxopyrrolidin-1-yl)ethyl]sulfanyl-4H-1,2,4-triazin-5-one —— C15H15N5O3S
    6-(2-aminophenyl)-3-[2-oxo-2-(2-oxopyrrolidin-1-yl)ethyl]sulfanyl-4H-1,2,4-triazin-5-one
    —— 2-[[(2R,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one —— C19H26N4O2S
    2-[[(2R,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one
    —— (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(furan-2-ylmethyl)propanamide —— C16H14ClN3O3S
    (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(furan-2-ylmethyl)propanamide
    —— (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclopropylpropanamide —— C14H14ClN3O2S
    (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclopropylpropanamide
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15Cl2N3O2S
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[(2S,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one —— C19H26N4O2S
    2-[[(2S,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one
    —— 2-[[(2S,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-3-ium-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one —— C19H27N4O2S+
    2-[[(2S,5R)-2-[4-(dimethylamino)phenyl]-1,3-oxazolidin-3-ium-5-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one
    —— (2R)-2-(4-chlorophenyl)sulfanyl-N-(4,5-dihydro-1,3-thiazol-2-yl)propanamide —— C12H13ClN2OS2
    (2R)-2-(4-chlorophenyl)sulfanyl-N-(4,5-dihydro-1,3-thiazol-2-yl)propanamide
    —— 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-pentan-2-yl]acetamide —— C15H18ClN3O2S
    2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-pentan-2-yl]acetamide
    —— 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(1-cyanocyclohexyl)acetamide —— C17H17ClN4O2S
    2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(1-cyanocyclohexyl)acetamide
    —— 4-[[5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-2-ethanimidoyl-3-oxobutanenitrile —— C14H11ClN4O2S
    4-[[5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-2-ethanimidoyl-3-oxobutanenitrile
    —— 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylacetamide —— C13H14ClN3O2S
    2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylacetamide
    —— (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[2-(cyclohexen-1-yl)ethyl]propanamide —— C19H22ClN3O2S
    (2S)-2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[2-(cyclohexen-1-yl)ethyl]propanamide
    —— 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methoxyethyl)acetamide —— C13H14ClN3O3S
    2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methoxyethyl)acetamide
    —— 2-[(3R)-oxolan-3-yl]-N-(5-thiophen-2-ylsulfanylpyridin-2-yl)acetamide —— C15H16N2O2S2
    2-[(3R)-oxolan-3-yl]-N-(5-thiophen-2-ylsulfanylpyridin-2-yl)acetamide
    —— N-(3,4-dimethylphenyl)-5-prop-2-enylsulfanyl-1,3,4-thiadiazol-2-amine —— C13H15N3S2
    N-(3,4-dimethylphenyl)-5-prop-2-enylsulfanyl-1,3,4-thiadiazol-2-amine
    —— 1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone —— C13H17NOS
    1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone
    —— 2-[(3S)-oxolan-3-yl]-N-(5-thiophen-2-ylsulfanylpyridin-2-yl)acetamide —— C15H16N2O2S2
    2-[(3S)-oxolan-3-yl]-N-(5-thiophen-2-ylsulfanylpyridin-2-yl)acetamide
    —— N-[(3S)-2,3-dihydro-1-benzothiophen-3-yl]-4-prop-2-enoxybutanamide —— C15H19NO2S
    N-[(3S)-2,3-dihydro-1-benzothiophen-3-yl]-4-prop-2-enoxybutanamide
    —— 2-[[(4R)-1,3-dioxan-4-yl]methylsulfanyl]-5-(3-phenylpropyl)-1,3,4-oxadiazole —— C16H20N2O3S
    2-[[(4R)-1,3-dioxan-4-yl]methylsulfanyl]-5-(3-phenylpropyl)-1,3,4-oxadiazole