摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-chloro-2-(2-chloroethyl)-1-propan-2-ylsulfanylbenzene —— C11H14Cl2S
    4-chloro-2-(2-chloroethyl)-1-propan-2-ylsulfanylbenzene
    —— 2-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-N-[4-(2,5-dimethylphenyl)sulfanylphenyl]acetamide —— C19H20N2OS3
    2-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-N-[4-(2,5-dimethylphenyl)sulfanylphenyl]acetamide
    —— 6-(3-chlorophenyl)-3-(trifluoromethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine —— C11H6ClF3N4S
    6-(3-chlorophenyl)-3-(trifluoromethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
    —— 2-[3-(5-chloro-2-methylsulfanylphenyl)imidazo[2,1-b][1,3]thiazol-6-yl]ethanamine —— C14H14ClN3S2
    2-[3-(5-chloro-2-methylsulfanylphenyl)imidazo[2,1-b][1,3]thiazol-6-yl]ethanamine
    —— 2-[3-(5-chloro-2-methylsulfanylphenyl)imidazo[2,1-b][1,3]thiazol-6-yl]acetic acid —— C14H11ClN2O2S2
    2-[3-(5-chloro-2-methylsulfanylphenyl)imidazo[2,1-b][1,3]thiazol-6-yl]acetic acid
    —— (R)-(5-chloro-2-propylsulfanylphenyl)-thiophen-2-ylmethanol —— C14H15ClOS2
    (R)-(5-chloro-2-propylsulfanylphenyl)-thiophen-2-ylmethanol
    —— 2-[3-(5-chloro-2-methylsulfanylphenyl)-2-methylimidazo[2,1-b][1,3]thiazol-6-yl]ethanamine —— C15H16ClN3S2
    2-[3-(5-chloro-2-methylsulfanylphenyl)-2-methylimidazo[2,1-b][1,3]thiazol-6-yl]ethanamine
    —— 2-[3-(5-chloro-2-methylsulfanylphenyl)-2-methylimidazo[2,1-b][1,3]thiazol-6-yl]acetic acid —— C15H13ClN2O2S2
    2-[3-(5-chloro-2-methylsulfanylphenyl)-2-methylimidazo[2,1-b][1,3]thiazol-6-yl]acetic acid
    —— 2-[3-(5-chloro-2-methylsulfanylphenyl)-6-methylimidazo[2,1-b][1,3]thiazol-5-yl]acetic acid —— C15H13ClN2O2S2
    2-[3-(5-chloro-2-methylsulfanylphenyl)-6-methylimidazo[2,1-b][1,3]thiazol-5-yl]acetic acid
    —— (S)-(5-methyl-2-methylsulfanylphenyl)-[(3S)-piperidin-3-yl]methanol —— C14H21NOS
    (S)-(5-methyl-2-methylsulfanylphenyl)-[(3S)-piperidin-3-yl]methanol
    —— 6-(4-fluorophenyl)-3-(2-methylfuran-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine —— C15H11FN4OS
    6-(4-fluorophenyl)-3-(2-methylfuran-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
    —— (S)-(5-chloro-2-propylsulfanylphenyl)-thiophen-2-ylmethanol —— C14H15ClOS2
    (S)-(5-chloro-2-propylsulfanylphenyl)-thiophen-2-ylmethanol
    —— (R)-(5-methyl-2-methylsulfanylphenyl)-[(3S)-piperidin-3-yl]methanol —— C14H21NOS
    (R)-(5-methyl-2-methylsulfanylphenyl)-[(3S)-piperidin-3-yl]methanol
    —— (S)-(5-methyl-2-methylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol —— C14H21NOS
    (S)-(5-methyl-2-methylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol
    —— (S)-(5-chloro-2-propylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol —— C15H22ClNOS
    (S)-(5-chloro-2-propylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol
    —— (R)-(5-methyl-2-methylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol —— C14H21NOS
    (R)-(5-methyl-2-methylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol
    —— (R)-(5-chloro-2-propylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol —— C15H22ClNOS
    (R)-(5-chloro-2-propylsulfanylphenyl)-[(3R)-piperidin-3-yl]methanol
    —— (R)-(5-chloro-2-propylsulfanylphenyl)-piperidin-4-ylmethanol —— C15H22ClNOS
    (R)-(5-chloro-2-propylsulfanylphenyl)-piperidin-4-ylmethanol
    —— 2-Ethyl-7-(pyrimidin-2-ylsulfanylmethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one —— C12H11N5OS2
    2-Ethyl-7-(pyrimidin-2-ylsulfanylmethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
    —— 7-[[5-(3,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-2-ethyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one —— C18H17N5O2S2
    7-[[5-(3,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-2-ethyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
    —— (S)-(5-methyl-2-methylsulfanylphenyl)-piperidin-4-ylmethanol —— C14H21NOS
    (S)-(5-methyl-2-methylsulfanylphenyl)-piperidin-4-ylmethanol
    —— 4-[(1-Cyclopropyltetrazol-5-yl)sulfanylmethyl]-2-thiophen-3-yl-1,3-thiazole —— C12H11N5S3
    4-[(1-Cyclopropyltetrazol-5-yl)sulfanylmethyl]-2-thiophen-3-yl-1,3-thiazole
    —— N-[(1S)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C19H26N4O3S2
    N-[(1S)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— N-(furan-2-ylmethyl)-N-methyl-2-[1-(thiophen-2-ylmethyl)tetrazol-5-yl]sulfanylacetamide —— C14H15N5O2S2
    N-(furan-2-ylmethyl)-N-methyl-2-[1-(thiophen-2-ylmethyl)tetrazol-5-yl]sulfanylacetamide
    —— 2-[5-[2-[[5-(Cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]thiophen-2-yl]acetamide —— C13H14N4O2S3
    2-[5-[2-[[5-(Cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]thiophen-2-yl]acetamide
    —— N-[(4-fluorophenyl)methyl]-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C16H19FN4O2S2
    N-[(4-fluorophenyl)methyl]-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 7-[[5-(Butylamino)-1,3,4-thiadiazol-2-yl]sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C13H15N5OS3
    7-[[5-(Butylamino)-1,3,4-thiadiazol-2-yl]sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— 5-[[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanylmethyl]-3-methyl-1,2-oxazole —— C22H20N4OS
    5-[[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanylmethyl]-3-methyl-1,2-oxazole
    —— N-[(4-methylphenyl)methyl]-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C17H22N4O2S2
    N-[(4-methylphenyl)methyl]-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— (2S)-N-cycloheptyl-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C17H28N4O2S2
    (2S)-N-cycloheptyl-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— N-[[(2S)-oxolan-2-yl]methyl]-5-thieno[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazol-2-amine —— C13H13N5OS3
    N-[[(2S)-oxolan-2-yl]methyl]-5-thieno[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazol-2-amine
    —— 1-[[5-[2-(Trifluoromethyl)quinazolin-4-yl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]pyrrolidin-2-one —— C16H12F3N5O2S
    1-[[5-[2-(Trifluoromethyl)quinazolin-4-yl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]pyrrolidin-2-one
    —— 2-[5-[2-(1-Cyclopentyltetrazol-5-yl)sulfanylacetyl]thiophen-2-yl]acetamide —— C14H17N5O2S2
    2-[5-[2-(1-Cyclopentyltetrazol-5-yl)sulfanylacetyl]thiophen-2-yl]acetamide
    —— 2-[(3-methyl-1,2-oxazol-5-yl)methylsulfanyl]-5-[(5S)-5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazole —— C16H17N3O2S2
    2-[(3-methyl-1,2-oxazol-5-yl)methylsulfanyl]-5-[(5S)-5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazole
    —— (2R)-N-[(1R)-1-phenylethyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propanamide —— C18H24N4OS
    (2R)-N-[(1R)-1-phenylethyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propanamide
    —— N-cyclopentyl-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C14H22N4O2S2
    N-cyclopentyl-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-(1-Benzyltetrazol-5-yl)sulfanyl-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone —— C19H18N6OS
    2-(1-Benzyltetrazol-5-yl)sulfanyl-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone
    —— 2-[(5S)-5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-5-(1,3-thiazol-4-ylmethylsulfanyl)-1,3,4-oxadiazole —— C15H15N3OS3
    2-[(5S)-5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-5-(1,3-thiazol-4-ylmethylsulfanyl)-1,3,4-oxadiazole
    —— 4-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanyl-6-phenylthieno[2,3-d]pyrimidine —— C18H16N6OS2
    4-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanyl-6-phenylthieno[2,3-d]pyrimidine
    —— 1-(2,5-dimethyl-1-propan-2-ylpyrrol-3-yl)-2-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanylethanone —— C17H25N5O2S
    1-(2,5-dimethyl-1-propan-2-ylpyrrol-3-yl)-2-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanylethanone
    —— (2S)-N-[(1S)-1-phenylethyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propanamide —— C18H24N4OS
    (2S)-N-[(1S)-1-phenylethyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propanamide
    —— 1-[2,5-Dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-[[5-(2-methylfuran-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C20H19N3O3S2
    1-[2,5-Dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-[[5-(2-methylfuran-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— 1-(3-methylsulfanylphenyl)-N-phenylmethoxymethanamine —— C15H17NOS
    1-(3-methylsulfanylphenyl)-N-phenylmethoxymethanamine
    —— 6-(2-hydroxyethyl)-7-methyl-2-methylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one —— C9H11N3O2S2
    6-(2-hydroxyethyl)-7-methyl-2-methylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
    —— ethyl (2Z)-2-[(5Z)-5-[(4-methylsulfanylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-ylidene]acetate —— C15H15NO2S3
    ethyl (2Z)-2-[(5Z)-5-[(4-methylsulfanylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-ylidene]acetate
    —— 6-(2-aminoethyl)-7-methyl-2-methylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one —— C9H12N4OS2
    6-(2-aminoethyl)-7-methyl-2-methylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
    —— 5-[(2R)-2-[hydroxy(methyl)amino]butan-2-yl]-1-benzothiophen-3-one —— C13H17NO2S
    5-[(2R)-2-[hydroxy(methyl)amino]butan-2-yl]-1-benzothiophen-3-one
    —— 5-[(2S)-2-[hydroxy(methyl)amino]butan-2-yl]-1-benzothiophen-3-one —— C13H17NO2S
    5-[(2S)-2-[hydroxy(methyl)amino]butan-2-yl]-1-benzothiophen-3-one
    —— 1-[(3R)-3-[hydroxy(methyl)amino]-3-methyl-2H-1-benzothiophen-5-yl]propan-1-one —— C13H17NO2S
    1-[(3R)-3-[hydroxy(methyl)amino]-3-methyl-2H-1-benzothiophen-5-yl]propan-1-one
    —— 1-[(3S)-3-[hydroxy(methyl)amino]-3-methyl-2H-1-benzothiophen-5-yl]propan-1-one —— C13H17NO2S
    1-[(3S)-3-[hydroxy(methyl)amino]-3-methyl-2H-1-benzothiophen-5-yl]propan-1-one