摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(4-chlorophenyl)methyl]-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C17H22ClN5O2S
    N-[(4-chlorophenyl)methyl]-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 7-[(4-Ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C15H18N6O2S2
    7-[(4-Ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S,2S)-2-methylcyclohexyl]acetamide —— C17H29N5O2S
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S,2S)-2-methylcyclohexyl]acetamide
    —— (2R)-N-cyclopentyl-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C16H27N5O2S
    (2R)-N-cyclopentyl-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-phenylpropyl)acetamide —— C19H27N5O2S
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-phenylpropyl)acetamide
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-methylbutylcarbamoyl)acetamide —— C16H28N6O3S
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-methylbutylcarbamoyl)acetamide
    —— (2S)-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide —— C19H26FN5O2S
    (2S)-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-N-(thiophen-2-ylmethyl)acetamide —— C16H23N5O2S2
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-N-(thiophen-2-ylmethyl)acetamide
    —— 4-[4-Ethyl-5-[(5-phenyl-1,3,4-oxadiazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]morpholine —— C17H20N6O2S
    4-[4-Ethyl-5-[(5-phenyl-1,3,4-oxadiazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]morpholine
    —— (2R)-4-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-2-(4-methyl-1,3-thiazol-2-yl)-3-oxobutanenitrile —— C16H20N6O2S2
    (2R)-4-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-2-(4-methyl-1,3-thiazol-2-yl)-3-oxobutanenitrile
    —— (2R)-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide —— C19H26FN5O2S
    (2R)-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide —— C20H29N5O2S
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide
    —— 2-(4-fluorophenyl)-5-[(1S)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-1,3,4-oxadiazole —— C13H12FN5OS
    2-(4-fluorophenyl)-5-[(1S)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-1,3,4-oxadiazole
    —— 2-(4-methylphenyl)-5-[(1R)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-1,3,4-oxadiazole —— C14H15N5OS
    2-(4-methylphenyl)-5-[(1R)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-1,3,4-oxadiazole
    —— N-cyclopentyl-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H25N5O2S
    N-cyclopentyl-2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 4-[5-[(4-Bromo-2-fluorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]morpholine —— C15H18BrFN4OS
    4-[5-[(4-Bromo-2-fluorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]morpholine
    —— 2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(4-fluorophenyl)ethyl]acetamide —— C18H24FN5O2S
    2-[(4-ethyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(4-fluorophenyl)ethyl]acetamide
    —— 2-(2,4-difluorophenyl)sulfanyl-1-[1-[(3R)-1,1-dioxothiolan-3-yl]-2,5-dimethylpyrrol-3-yl]ethanone —— C18H19F2NO3S2
    2-(2,4-difluorophenyl)sulfanyl-1-[1-[(3R)-1,1-dioxothiolan-3-yl]-2,5-dimethylpyrrol-3-yl]ethanone
    —— 2-(2,4-difluorophenyl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]acetamide —— C12H13F2NO3S2
    2-(2,4-difluorophenyl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]acetamide
    —— 2-(2,4-difluorophenyl)sulfanyl-1-[1-[(3S)-1,1-dioxothiolan-3-yl]-2,5-dimethylpyrrol-3-yl]ethanone —— C18H19F2NO3S2
    2-(2,4-difluorophenyl)sulfanyl-1-[1-[(3S)-1,1-dioxothiolan-3-yl]-2,5-dimethylpyrrol-3-yl]ethanone
    —— ethyl 5-[2-(2,4-difluorophenyl)sulfanylacetyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C17H17F2NO3S
    ethyl 5-[2-(2,4-difluorophenyl)sulfanylacetyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— 2-(2,4-difluorophenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]acetamide —— C12H13F2NO3S2
    2-(2,4-difluorophenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]acetamide
    —— (2S)-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N,N-dimethylpropanamide —— C13H15FN4OS2
    (2S)-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N,N-dimethylpropanamide
    —— (2R)-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N,N-dimethylpropanamide —— C13H15FN4OS2
    (2R)-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N,N-dimethylpropanamide
    —— (2S)-N-ethyl-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C13H15FN4OS2
    (2S)-N-ethyl-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— N-(cyclohexen-1-yl)-N-cyclopropyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C18H20N4O2S
    N-(cyclohexen-1-yl)-N-cyclopropyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— N-[2-[(5-methylfuran-2-yl)methyl]pyrazol-3-yl]-2-(4-methylphenyl)sulfanylpyridine-3-carboxamide —— C22H20N4O2S
    N-[2-[(5-methylfuran-2-yl)methyl]pyrazol-3-yl]-2-(4-methylphenyl)sulfanylpyridine-3-carboxamide
    —— 2-{[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(1-cyanocyclopentyl)acetamide —— C16H15F3N4OS
    2-{[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(1-cyanocyclopentyl)acetamide
    —— 2-(2-cyanophenyl)sulfanyl-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)benzamide —— C21H15N5OS
    2-(2-cyanophenyl)sulfanyl-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)benzamide
    —— 2-[(3,4-Dimethylphenyl)sulfanylmethyl]-5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,3,4-oxadiazole —— C21H19N3O2S
    2-[(3,4-Dimethylphenyl)sulfanylmethyl]-5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,3,4-oxadiazole
    —— 1-[1-[2-(4-Chlorophenyl)sulfanylethyl]pyridin-1-ium-3-yl]ethanone —— C15H15ClNOS+
    1-[1-[2-(4-Chlorophenyl)sulfanylethyl]pyridin-1-ium-3-yl]ethanone
    —— 2-(3-acetylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide —— C21H19N2O2S+
    2-(3-acetylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide
    —— 2-amino-6-(2-methylsulfanylphenyl)-1H-1,3,5-triazine-4-thione —— C10H10N4S2
    2-amino-6-(2-methylsulfanylphenyl)-1H-1,3,5-triazine-4-thione
    —— (2Z)-2-[(5Z)-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]acetonitrile —— C14H12N2OS2
    (2Z)-2-[(5Z)-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]acetonitrile
    —— N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(2,3-dimethylpyridin-1-ium-1-yl)acetamide —— C21H20ClN2OS+
    N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(2,3-dimethylpyridin-1-ium-1-yl)acetamide
    —— N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(4-methylpyridin-1-ium-1-yl)acetamide —— C20H18ClN2OS+
    N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(4-methylpyridin-1-ium-1-yl)acetamide
    —— 2-(4-methylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide —— C20H19N2OS+
    2-(4-methylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N'-(1,3,5-trimethylpyrazol-4-yl)sulfonylacetohydrazide —— C14H17ClN4O3S2
    2-(4-chlorophenyl)sulfanyl-N'-(1,3,5-trimethylpyrazol-4-yl)sulfonylacetohydrazide
    —— [(2S)-1-amino-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C12H13F2NO3S
    [(2S)-1-amino-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [(2R)-1-amino-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C12H13F2NO3S
    [(2R)-1-amino-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C17H20F2N2O3S
    [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [2-(Tert-butylamino)-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C15H19F2NO3S
    [2-(Tert-butylamino)-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— (2R)-3-[3-[4-(2-methylpropyl)-5-methylsulfanyl-1,2,4-triazol-3-yl]propylimino]-2-(4-methyl-1,3-thiazol-2-yl)propanenitrile —— C17H24N6S2
    (2R)-3-[3-[4-(2-methylpropyl)-5-methylsulfanyl-1,2,4-triazol-3-yl]propylimino]-2-(4-methyl-1,3-thiazol-2-yl)propanenitrile
    —— [2-[[(3R)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C15H17F2NO5S2
    [2-[[(3R)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [(2S)-1-(cyclopropylamino)-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C15H17F2NO3S
    [(2S)-1-(cyclopropylamino)-1-oxopropan-2-yl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [2-[[(1R,2R)-2-methylcyclohexyl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C18H23F2NO3S
    [2-[[(1R,2R)-2-methylcyclohexyl]amino]-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— ethyl (2S)-2-cyano-3-[3-(4-cyclopentyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propylimino]propanoate —— C17H25N5O2S
    ethyl (2S)-2-cyano-3-[3-(4-cyclopentyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propylimino]propanoate
    —— [2-(Cyclohexylamino)-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate —— C17H21F2NO3S
    [2-(Cyclohexylamino)-2-oxoethyl] 3-(3,4-difluorophenyl)sulfanylpropanoate
    —— [2-oxo-2-(pentan-3-ylamino)ethyl] (2R)-2-phenyl-2-phenylsulfanylacetate —— C21H25NO3S
    [2-oxo-2-(pentan-3-ylamino)ethyl] (2R)-2-phenyl-2-phenylsulfanylacetate
    —— [2-[[(3S)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] (2R)-2-phenyl-2-phenylsulfanylacetate —— C20H21NO5S2
    [2-[[(3S)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] (2R)-2-phenyl-2-phenylsulfanylacetate