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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-methyl-N-[(1R)-1-phenylethyl]acetamide —— C19H21N3OS
    2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-methyl-N-[(1R)-1-phenylethyl]acetamide
    —— 2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-methyl-N-[(1S)-1-phenylethyl]acetamide —— C19H21N3OS
    2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-methyl-N-[(1S)-1-phenylethyl]acetamide
    —— (2R)-2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-propan-2-ylpropanamide —— C14H19N3OS
    (2R)-2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanyl-N-propan-2-ylpropanamide
    —— (2R)-N-[(1S)-1-phenylbutyl]-2-[[5-(prop-2-enylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C18H24N4OS2
    (2R)-N-[(1S)-1-phenylbutyl]-2-[[5-(prop-2-enylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— N-(furan-2-ylmethyl)-2-[[5-(prop-2-enylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2,2,2-trifluoroethyl)acetamide —— C14H15F3N4O2S2
    N-(furan-2-ylmethyl)-2-[[5-(prop-2-enylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2,2,2-trifluoroethyl)acetamide
    —— 7-chloro-4-methyl-2,3-dihydro-1-benzothiophen-5-amine —— C9H10ClNS
    7-chloro-4-methyl-2,3-dihydro-1-benzothiophen-5-amine
    —— (2R)-5-amino-6-chloro-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8ClNO2S
    (2R)-5-amino-6-chloro-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— 5-[[2-(4-ethylphenyl)-1,3-thiazol-4-yl]methylsulfanyl]-N-prop-2-enyl-1,3,4-thiadiazol-2-amine —— C17H18N4S3
    5-[[2-(4-ethylphenyl)-1,3-thiazol-4-yl]methylsulfanyl]-N-prop-2-enyl-1,3,4-thiadiazol-2-amine
    —— (2S)-4-amino-5-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2S)-4-amino-5-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2R)-7-amino-6-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2R)-7-amino-6-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— 7-bromo-2,3-dihydro-1-benzothiophen-4-amine —— C8H8BrNS
    7-bromo-2,3-dihydro-1-benzothiophen-4-amine
    —— (2R)-4-amino-5-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2R)-4-amino-5-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2S)-5-amino-4-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2S)-5-amino-4-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2R)-5-amino-4-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2R)-5-amino-4-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2S)-5-amino-6-chloro-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8ClNO2S
    (2S)-5-amino-6-chloro-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2S)-4-amino-7-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2S)-4-amino-7-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— 5-bromo-2,3-dihydro-1-benzothiophen-4-amine —— C8H8BrNS
    5-bromo-2,3-dihydro-1-benzothiophen-4-amine
    —— 6-chloro-2,3-dihydro-1-benzothiophen-5-amine —— C8H8ClNS
    6-chloro-2,3-dihydro-1-benzothiophen-5-amine
    —— 7-chloro-5-fluoro-2,3-dihydro-1-benzothiophen-4-amine —— C8H7ClFNS
    7-chloro-5-fluoro-2,3-dihydro-1-benzothiophen-4-amine
    —— (2S)-7-amino-6-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2S)-7-amino-6-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (2R)-4-amino-7-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid —— C9H8BrNO2S
    (2R)-4-amino-7-bromo-2,3-dihydro-1-benzothiophene-2-carboxylic acid
    —— (5E)-2-(2,4-difluorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C21H20F2N2OS2
    (5E)-2-(2,4-difluorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-3-methyl-2-(2-methylphenyl)imino-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C19H18N2OS2
    (5E)-3-methyl-2-(2-methylphenyl)imino-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-2-(3-chlorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C21H21ClN2OS2
    (5E)-2-(3-chlorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (2E)-2-(2,5,6,7,8,9-hexahydro-[1,2,4]triazolo[4,3-a]azepin-3-ylidene)-3-oxo-4-pyrimidin-2-ylsulfanylbutanenitrile —— C15H16N6OS
    (2E)-2-(2,5,6,7,8,9-hexahydro-[1,2,4]triazolo[4,3-a]azepin-3-ylidene)-3-oxo-4-pyrimidin-2-ylsulfanylbutanenitrile
    —— (5E)-2-(4-fluorophenyl)imino-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C18H15FN2OS2
    (5E)-2-(4-fluorophenyl)imino-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-2-(2-chlorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C21H21ClN2OS2
    (5E)-2-(2-chlorophenyl)imino-3-(2-methylpropyl)-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-2-(2-chlorophenyl)imino-3-ethyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C19H17ClN2OS2
    (5E)-2-(2-chlorophenyl)imino-3-ethyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-2-(3-chlorophenyl)imino-3-ethyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C19H17ClN2OS2
    (5E)-2-(3-chlorophenyl)imino-3-ethyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-2-(2-fluorophenyl)imino-3-methyl-5-[(5-phenylsulfanylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one —— C21H15FN2O2S2
    (5E)-2-(2-fluorophenyl)imino-3-methyl-5-[(5-phenylsulfanylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-5-[(3-hydroxyphenyl)methylidene]-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C18H16N2O2S2
    (5E)-5-[(3-hydroxyphenyl)methylidene]-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— (5E)-3-methyl-5-[(5-methylfuran-2-yl)methylidene]-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C17H16N2O2S2
    (5E)-3-methyl-5-[(5-methylfuran-2-yl)methylidene]-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— (5E)-2-(2-fluorophenyl)imino-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C18H15FN2OS2
    (5E)-2-(2-fluorophenyl)imino-3-methyl-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-3-methyl-2-(3-methylsulfanylphenyl)imino-5-[(5-morpholin-4-ylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one —— C20H21N3O3S2
    (5E)-3-methyl-2-(3-methylsulfanylphenyl)imino-5-[(5-morpholin-4-ylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-3-methyl-2-phenylimino-5-[(5-phenylsulfanylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one —— C21H16N2O2S2
    (5E)-3-methyl-2-phenylimino-5-[(5-phenylsulfanylfuran-2-yl)methylidene]-1,3-thiazolidin-4-one
    —— (5E)-5-(furan-2-ylmethylidene)-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C16H14N2O2S2
    (5E)-5-(furan-2-ylmethylidene)-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— (5E)-5-benzylidene-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C18H16N2OS2
    (5E)-5-benzylidene-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— (5E)-3-ethyl-2-(4-methylphenyl)imino-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C20H20N2OS2
    (5E)-3-ethyl-2-(4-methylphenyl)imino-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— (2R)-2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]propanoate —— C5H6N3O2S2-
    (2R)-2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]propanoate
    —— (5E)-5-[(4-chlorophenyl)methylidene]-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C18H15ClN2OS2
    (5E)-5-[(4-chlorophenyl)methylidene]-3-methyl-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— (5E)-3-methyl-5-[(4-methylphenyl)methylidene]-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one —— C19H18N2OS2
    (5E)-3-methyl-5-[(4-methylphenyl)methylidene]-2-(3-methylsulfanylphenyl)imino-1,3-thiazolidin-4-one
    —— 3-[(4-Phenyl-1,3-thiazol-2-yl)sulfanyl]propanoate —— C12H10NO2S2-
    3-[(4-Phenyl-1,3-thiazol-2-yl)sulfanyl]propanoate
    —— (2S)-2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]propanoic acid —— C5H8N4O2S
    (2S)-2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]propanoic acid
    —— 3-(Pyrimidin-2-ylsulfanyl)propanoic acid 919466-99-2 C7H8N2O2S
    3-(Pyrimidin-2-ylsulfanyl)propanoic acid
    —— [2-oxo-2-[[(1R)-1-phenylbutyl]amino]ethyl] 2-(2-fluorophenyl)sulfanylacetate —— C20H22FNO3S
    [2-oxo-2-[[(1R)-1-phenylbutyl]amino]ethyl] 2-(2-fluorophenyl)sulfanylacetate
    —— 3-[(4-Phenyl-5-sulfanylidene-1,3,4-thiadiazol-2-yl)sulfanyl]propanoate —— C11H9N2O2S3-
    3-[(4-Phenyl-5-sulfanylidene-1,3,4-thiadiazol-2-yl)sulfanyl]propanoate
    —— [(2S)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,4-dimethylphenyl)sulfanylacetate —— C16H23NO3S
    [(2S)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,4-dimethylphenyl)sulfanylacetate
    —— (2S)-2-pyrimidin-2-ylsulfanylpropanoate —— C7H7N2O2S-
    (2S)-2-pyrimidin-2-ylsulfanylpropanoate
    —— (2S)-2-[(4-phenyl-1,3-thiazol-2-yl)sulfanyl]propanoate —— C12H10NO2S2-
    (2S)-2-[(4-phenyl-1,3-thiazol-2-yl)sulfanyl]propanoate
    —— 2-[(3-Methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetate —— C5H5N2O2S3-
    2-[(3-Methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetate