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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-(4-methylphenyl)-4-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3-thiazol-2-amine —— C20H18N4OS2
    N-(4-methylphenyl)-4-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3-thiazol-2-amine
    —— 5-chloro-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyrimidine —— C10H14ClN3S
    5-chloro-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyrimidine
    —— 3-chloro-6-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridazine —— C10H14ClN3S
    3-chloro-6-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridazine
    —— (1E)-1-({5-[(4-methylphenyl)sulfanyl]furan-2-yl}methylidene)-2-(4-nitrophenyl)hydrazine —— C18H15N3O3S
    (1E)-1-({5-[(4-methylphenyl)sulfanyl]furan-2-yl}methylidene)-2-(4-nitrophenyl)hydrazine
    —— 3-chloro-6-[(3S)-piperidin-3-yl]sulfanylpyridazine —— C9H12ClN3S
    3-chloro-6-[(3S)-piperidin-3-yl]sulfanylpyridazine
    —— 3-chloro-6-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridazine —— C10H14ClN3S
    3-chloro-6-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridazine
    —— 3-chloro-6-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridazine —— C10H14ClN3S
    3-chloro-6-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridazine
    —— 3-chloro-6-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridazine —— C9H12ClN3S
    3-chloro-6-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridazine
    —— 3-chloro-6-[(3R)-piperidin-3-yl]sulfanylpyridazine —— C9H12ClN3S
    3-chloro-6-[(3R)-piperidin-3-yl]sulfanylpyridazine
    —— 3-chloro-6-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridazine —— C9H12ClN3S
    3-chloro-6-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridazine
    —— 3-chloro-6-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridazine —— C9H12ClN3S
    3-chloro-6-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridazine
    —— ethyl (2R)-2-(4-tert-butyl-1-methyl-6-oxopyrimidin-2-yl)sulfanylpropanoate —— C14H22N2O3S
    ethyl (2R)-2-(4-tert-butyl-1-methyl-6-oxopyrimidin-2-yl)sulfanylpropanoate
    —— 3-chloro-6-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridazine —— C9H12ClN3S
    3-chloro-6-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridazine
    —— ethyl (2S)-2-(4-tert-butyl-1-methyl-6-oxopyrimidin-2-yl)sulfanylpropanoate —— C14H22N2O3S
    ethyl (2S)-2-(4-tert-butyl-1-methyl-6-oxopyrimidin-2-yl)sulfanylpropanoate
    —— 2-[(3,4-Difluorophenyl)methylsulfanyl]-3,6-dimethyl-5-[(3-methylphenyl)methyl]pyrimidin-4-one —— C21H20F2N2OS
    2-[(3,4-Difluorophenyl)methylsulfanyl]-3,6-dimethyl-5-[(3-methylphenyl)methyl]pyrimidin-4-one
    —— (2S)-2-(4-chlorophenyl)sulfanyl-N-(pentan-3-ylideneamino)propanamide —— C14H19ClN2OS
    (2S)-2-(4-chlorophenyl)sulfanyl-N-(pentan-3-ylideneamino)propanamide
    —— 5-methyl-2-[(3S)-piperidin-3-yl]sulfanylpyridine —— C11H16N2S
    5-methyl-2-[(3S)-piperidin-3-yl]sulfanylpyridine
    —— 4-chloro-6-methyl-2-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyrimidine
    —— 4-chloro-6-methyl-2-[[(3R)-piperidin-3-yl]methylsulfanyl]pyrimidine —— C11H16ClN3S
    4-chloro-6-methyl-2-[[(3R)-piperidin-3-yl]methylsulfanyl]pyrimidine
    —— 4-methyl-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridine —— C12H18N2S
    4-methyl-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridine
    —— 4-chloro-6-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyrimidine —— C11H16ClN3S
    4-chloro-6-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyrimidine
    —— 4-chloro-6-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyrimidine
    —— 4-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridine
    —— 4-chloro-6-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyrimidine
    —— 4-chloro-6-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyrimidine
    —— 4-chloro-6-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyrimidine
    —— 4-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine —— C12H18N2S
    4-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine
    —— 5-methyl-2-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridine —— C11H16N2S
    5-methyl-2-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridine
    —— 5-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    5-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridine
    —— 4-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-methyl-2-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridine
    —— 4-chloro-6-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyrimidine —— C11H16ClN3S
    4-chloro-6-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyrimidine
    —— 3-methyl-6-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridazine —— C10H15N3S
    3-methyl-6-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]pyridazine
    —— 4-chloro-6-methyl-2-[(3S)-piperidin-3-yl]sulfanylpyrimidine —— C10H14ClN3S
    4-chloro-6-methyl-2-[(3S)-piperidin-3-yl]sulfanylpyrimidine
    —— 5-methyl-2-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridine —— C12H18N2S
    5-methyl-2-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridine
    —— 4-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridine
    —— 3-methyl-6-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridazine —— C10H15N3S
    3-methyl-6-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridazine
    —— 3-methyl-6-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridazine —— C11H17N3S
    3-methyl-6-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridazine
    —— 3-methyl-6-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridazine —— C11H17N3S
    3-methyl-6-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridazine
    —— 5-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    5-methyl-2-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridine
    —— 3-methyl-6-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridazine —— C11H17N3S
    3-methyl-6-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridazine
    —— 5-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine —— C12H18N2S
    5-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine
    —— 5-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyridine —— C11H16N2S
    5-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyridine
    —— 5-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine —— C12H18N2S
    5-methyl-2-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine
    —— 4-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyridine —— C11H16N2S
    4-methyl-2-[(3R)-piperidin-3-yl]sulfanylpyridine
    —— 5-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridine —— C11H16N2S
    5-methyl-2-[[(2R)-pyrrolidin-2-yl]methylsulfanyl]pyridine
    —— 3-methyl-6-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridazine —— C10H15N3S
    3-methyl-6-[[(2S)-pyrrolidin-2-yl]methylsulfanyl]pyridazine
    —— 3-methyl-6-[(3S)-piperidin-3-yl]sulfanylpyridazine —— C10H15N3S
    3-methyl-6-[(3S)-piperidin-3-yl]sulfanylpyridazine
    —— 4-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine —— C12H18N2S
    4-methyl-2-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine
    —— 3-methyl-6-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridazine —— C10H15N3S
    3-methyl-6-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]pyridazine
    —— 4-chloro-6-methyl-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyrimidine —— C11H16ClN3S
    4-chloro-6-methyl-2-[[(2R)-piperidin-2-yl]methylsulfanyl]pyrimidine