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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]methyl]acetamide
    —— 5-[(2R)-3-amino-2-hydroxy-2-methylpropyl]-1-benzothiophen-3-one —— C12H15NO2S
    5-[(2R)-3-amino-2-hydroxy-2-methylpropyl]-1-benzothiophen-3-one
    —— 1-[(3S)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-1-one —— C12H15NO2S
    1-[(3S)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-1-one
    —— (2R)-2-cyclopentyl-2-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethanamine —— C11H18N4S
    (2R)-2-cyclopentyl-2-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethanamine
    —— N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]methyl]acetamide
    —— N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]methyl]acetamide
    —— N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]methyl]acetamide
    —— (3S,4R)-1-methyl-4-(2-methylsulfanylpyrimidin-4-yl)piperidin-3-amine —— C11H18N4S
    (3S,4R)-1-methyl-4-(2-methylsulfanylpyrimidin-4-yl)piperidin-3-amine
    —— 5-[(2R)-1-amino-2-hydroxybutan-2-yl]-1-benzothiophen-3-one —— C12H15NO2S
    5-[(2R)-1-amino-2-hydroxybutan-2-yl]-1-benzothiophen-3-one
    —— N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]methyl]acetamide
    —— (3S,4S)-1-methyl-4-(2-methylsulfanylpyrimidin-4-yl)piperidin-3-amine —— C11H18N4S
    (3S,4S)-1-methyl-4-(2-methylsulfanylpyrimidin-4-yl)piperidin-3-amine
    —— (2S)-2-cyclopentyl-2-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethanamine —— C11H18N4S
    (2S)-2-cyclopentyl-2-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)ethanamine
    —— 5-[(2S)-3-amino-2-hydroxy-2-methylpropyl]-1-benzothiophen-3-one —— C12H15NO2S
    5-[(2S)-3-amino-2-hydroxy-2-methylpropyl]-1-benzothiophen-3-one
    —— 1-[(3R)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-1-one —— C12H15NO2S
    1-[(3R)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-1-one
    —— N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]methyl]acetamide —— C12H15NO2S
    N-hydroxy-N-[[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]methyl]acetamide
    —— 1-[(3R)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-2-one —— C12H15NO2S
    1-[(3R)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-2-one
    —— 5-[(1S)-1-[hydroxy(methyl)amino]propyl]-1-benzothiophen-3-one —— C12H15NO2S
    5-[(1S)-1-[hydroxy(methyl)amino]propyl]-1-benzothiophen-3-one
    —— 1-[(3S)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-2-one —— C12H15NO2S
    1-[(3S)-3-(aminomethyl)-3-hydroxy-2H-1-benzothiophen-5-yl]propan-2-one
    —— 5-[(2S)-2-(methylamino)butan-2-yl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(2S)-2-(methylamino)butan-2-yl]-1-benzothiophen-3-one
    —— (3S)-3-(2,3-dihydro-1-benzothiophen-5-yl)-4-methylpentan-1-amine —— C14H21NS
    (3S)-3-(2,3-dihydro-1-benzothiophen-5-yl)-4-methylpentan-1-amine
    —— (3S)-3-(2,3-dihydro-1-benzothiophen-6-yl)-4-methylpentan-1-amine —— C14H21NS
    (3S)-3-(2,3-dihydro-1-benzothiophen-6-yl)-4-methylpentan-1-amine
    —— (2R)-2-methyl-3-(3-oxo-1-benzothiophen-5-yl)propanoic acid —— C12H12O3S
    (2R)-2-methyl-3-(3-oxo-1-benzothiophen-5-yl)propanoic acid
    —— (2S)-2-(3-oxo-1-benzothiophen-5-yl)butanoic acid —— C12H12O3S
    (2S)-2-(3-oxo-1-benzothiophen-5-yl)butanoic acid
    —— (2R)-2-(3-oxo-1-benzothiophen-5-yl)butanoic acid —— C12H12O3S
    (2R)-2-(3-oxo-1-benzothiophen-5-yl)butanoic acid
    —— (2R)-3-methyl-2-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine —— C14H21NS
    (2R)-3-methyl-2-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine
    —— (2R)-3-methyl-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine —— C14H21NS
    (2R)-3-methyl-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine
    —— 5-[(3S)-1-aminopentan-3-yl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(3S)-1-aminopentan-3-yl]-1-benzothiophen-3-one
    —— (2S)-3-methyl-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine —— C14H21NS
    (2S)-3-methyl-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine
    —— (3R)-3-(2,3-dihydro-1-benzothiophen-7-yl)-4-methylpentan-1-amine —— C14H21NS
    (3R)-3-(2,3-dihydro-1-benzothiophen-7-yl)-4-methylpentan-1-amine
    —— 5-[(3R)-1-aminopentan-3-yl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(3R)-1-aminopentan-3-yl]-1-benzothiophen-3-one
    —— 5-[(2R)-2-(methylamino)butan-2-yl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(2R)-2-(methylamino)butan-2-yl]-1-benzothiophen-3-one
    —— 5-[(2S)-4-amino-2-methylbutyl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(2S)-4-amino-2-methylbutyl]-1-benzothiophen-3-one
    —— (3R)-3-(2,3-dihydro-1-benzothiophen-6-yl)-4-methylpentan-1-amine —— C14H21NS
    (3R)-3-(2,3-dihydro-1-benzothiophen-6-yl)-4-methylpentan-1-amine
    —— (2S)-3-methyl-2-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine —— C14H21NS
    (2S)-3-methyl-2-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]butan-1-amine
    —— 5-[(2R)-4-amino-2-methylbutyl]-1-benzothiophen-3-one —— C13H17NOS
    5-[(2R)-4-amino-2-methylbutyl]-1-benzothiophen-3-one
    —— 1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropane-1-carboxylic acid —— C13H14O2S
    1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropane-1-carboxylic acid
    —— (3S)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine —— C14H19NS
    (3S)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine
    —— 1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropane-1-carboxylic acid —— C13H14O2S
    1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropane-1-carboxylic acid
    —— (2S)-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine —— C14H19NS
    (2S)-2-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine
    —— 1-(2,3-dihydro-1-benzothiophen-4-yl)cyclobutane-1-carboxylic acid —— C13H14O2S
    1-(2,3-dihydro-1-benzothiophen-4-yl)cyclobutane-1-carboxylic acid
    —— 1-(2,3-dihydro-1-benzothiophen-6-yl)cyclobutane-1-carboxylic acid —— C13H14O2S
    1-(2,3-dihydro-1-benzothiophen-6-yl)cyclobutane-1-carboxylic acid
    —— (3S)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine —— C14H19NS
    (3S)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine
    —— (3R)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine —— C14H19NS
    (3R)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine
    —— 1-(2,3-dihydro-1-benzothiophen-7-yl)cyclobutane-1-carboxylic acid —— C13H14O2S
    1-(2,3-dihydro-1-benzothiophen-7-yl)cyclobutane-1-carboxylic acid
    —— (3R)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine —— C14H19NS
    (3R)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]piperidine
    —— methyl (2E)-2-cyano-3-{4-[(1-methyl(1,2,3,4-tetraazol-5-ylthio))methyl](2-thie nyl)}prop-2-enoate —— C12H11N5O2S2
    methyl (2E)-2-cyano-3-{4-[(1-methyl(1,2,3,4-tetraazol-5-ylthio))methyl](2-thie nyl)}prop-2-enoate
    —— 1-(2,3-dihydro-1-benzothiophen-5-yl)cyclobutane-1-carboxylic acid —— C13H14O2S
    1-(2,3-dihydro-1-benzothiophen-5-yl)cyclobutane-1-carboxylic acid
    —— (2S)-2-(4-methyl-2-methylsulfanylpyrimidin-5-yl)morpholine —— C10H15N3OS
    (2S)-2-(4-methyl-2-methylsulfanylpyrimidin-5-yl)morpholine
    —— (7R)-7-(2-methylsulfanylpyrimidin-5-yl)-1,4-oxazepane —— C10H15N3OS
    (7R)-7-(2-methylsulfanylpyrimidin-5-yl)-1,4-oxazepane
    —— (3R)-3-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)-4-methylpentan-1-amine —— C10H18N4S
    (3R)-3-(5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazol-2-yl)-4-methylpentan-1-amine