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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S,3Z)-3-cyclopropyl-2-ethylsulfonyl-3-hydroxyiminopropan-1-ol —— C8H15NO4S
    (2S,3Z)-3-cyclopropyl-2-ethylsulfonyl-3-hydroxyiminopropan-1-ol
    —— (1R,2R)-1-cyclopropyl-2-methylsulfonylpropan-1-amine —— C7H15NO2S
    (1R,2R)-1-cyclopropyl-2-methylsulfonylpropan-1-amine
    —— (3R,4R)-4-ethylsulfonyl-2,2-dimethylpentan-3-amine —— C9H21NO2S
    (3R,4R)-4-ethylsulfonyl-2,2-dimethylpentan-3-amine
    —— (3S,4S)-4-ethylsulfonyl-2,2-dimethylpentan-3-amine —— C9H21NO2S
    (3S,4S)-4-ethylsulfonyl-2,2-dimethylpentan-3-amine
    —— (1S,2S)-1-cyclopropyl-2-methylsulfonylpropan-1-amine —— C7H15NO2S
    (1S,2S)-1-cyclopropyl-2-methylsulfonylpropan-1-amine
    —— (3R,4R)-2,2-dimethyl-4-methylsulfonylpentan-3-amine —— C8H19NO2S
    (3R,4R)-2,2-dimethyl-4-methylsulfonylpentan-3-amine
    —— (2S,3E)-2-ethylsulfonyl-3-hydroxyiminobutan-1-ol —— C6H13NO4S
    (2S,3E)-2-ethylsulfonyl-3-hydroxyiminobutan-1-ol
    —— (2R,3Z)-3-cyclopropyl-3-hydroxyimino-2-methylsulfonylpropan-1-ol —— C7H13NO4S
    (2R,3Z)-3-cyclopropyl-3-hydroxyimino-2-methylsulfonylpropan-1-ol
    —— (2S,3Z)-3-hydroxyimino-4,4-dimethyl-2-methylsulfonylpentan-1-ol —— C8H17NO4S
    (2S,3Z)-3-hydroxyimino-4,4-dimethyl-2-methylsulfonylpentan-1-ol
    —— (NZ)-N-[(3R)-3-ethylsulfonylpentan-2-ylidene]hydroxylamine —— C7H15NO3S
    (NZ)-N-[(3R)-3-ethylsulfonylpentan-2-ylidene]hydroxylamine
    —— (NZ)-N-[(4S)-4-ethylsulfonyl-2,2-dimethylhexan-3-ylidene]hydroxylamine —— C10H21NO3S
    (NZ)-N-[(4S)-4-ethylsulfonyl-2,2-dimethylhexan-3-ylidene]hydroxylamine
    —— (2S,3E)-2-ethylsulfonyl-3-hydroxyimino-4,4-dimethylpentan-1-ol —— C9H19NO4S
    (2S,3E)-2-ethylsulfonyl-3-hydroxyimino-4,4-dimethylpentan-1-ol
    —— (2R,3Z)-3-hydroxyimino-2-methylsulfonylbutan-1-ol —— C5H11NO4S
    (2R,3Z)-3-hydroxyimino-2-methylsulfonylbutan-1-ol
    —— (NZ)-N-[(2R)-1-cyclopropyl-2-ethylsulfonylpropylidene]hydroxylamine —— C8H15NO3S
    (NZ)-N-[(2R)-1-cyclopropyl-2-ethylsulfonylpropylidene]hydroxylamine
    —— (NZ)-N-(1-ethylsulfonylpropan-2-ylidene)hydroxylamine —— C5H11NO3S
    (NZ)-N-(1-ethylsulfonylpropan-2-ylidene)hydroxylamine
    —— (NZ)-N-[(3R)-3-ethylsulfonylbutan-2-ylidene]hydroxylamine —— C6H13NO3S
    (NZ)-N-[(3R)-3-ethylsulfonylbutan-2-ylidene]hydroxylamine
    —— (2S,3Z)-3-hydroxyimino-2-methylsulfonylbutan-1-ol —— C5H11NO4S
    (2S,3Z)-3-hydroxyimino-2-methylsulfonylbutan-1-ol
    —— (NZ)-N-[(2R)-1-cyclopropyl-2-ethylsulfonylbutylidene]hydroxylamine —— C9H17NO3S
    (NZ)-N-[(2R)-1-cyclopropyl-2-ethylsulfonylbutylidene]hydroxylamine
    —— (NZ)-N-[(2S)-1-cyclopropyl-2-ethylsulfonylpropylidene]hydroxylamine —— C8H15NO3S
    (NZ)-N-[(2S)-1-cyclopropyl-2-ethylsulfonylpropylidene]hydroxylamine
    —— (NZ)-N-[(2R)-1-cyclopropyl-2-methylsulfonylpropylidene]hydroxylamine —— C7H13NO3S
    (NZ)-N-[(2R)-1-cyclopropyl-2-methylsulfonylpropylidene]hydroxylamine
    —— (2S,3Z)-3-cyclopropyl-3-hydroxyimino-2-methylsulfonylpropan-1-ol —— C7H13NO4S
    (2S,3Z)-3-cyclopropyl-3-hydroxyimino-2-methylsulfonylpropan-1-ol
    —— (NZ)-N-[(4R)-2,2-dimethyl-4-methylsulfonylpentan-3-ylidene]hydroxylamine —— C8H17NO3S
    (NZ)-N-[(4R)-2,2-dimethyl-4-methylsulfonylpentan-3-ylidene]hydroxylamine
    —— (NZ)-N-[(4R)-2,2-dimethyl-4-methylsulfonylhexan-3-ylidene]hydroxylamine —— C9H19NO3S
    (NZ)-N-[(4R)-2,2-dimethyl-4-methylsulfonylhexan-3-ylidene]hydroxylamine
    —— (NZ)-N-[(2S)-1-cyclopropyl-2-ethylsulfonylbutylidene]hydroxylamine —— C9H17NO3S
    (NZ)-N-[(2S)-1-cyclopropyl-2-ethylsulfonylbutylidene]hydroxylamine
    —— N-[(1S)-1-(2,4-difluorophenyl)ethyl]-3-(4-fluorophenyl)sulfanylpropanamide —— C17H16F3NOS
    N-[(1S)-1-(2,4-difluorophenyl)ethyl]-3-(4-fluorophenyl)sulfanylpropanamide
    —— (NZ)-N-[(3S)-3-ethylsulfonylbutan-2-ylidene]hydroxylamine —— C6H13NO3S
    (NZ)-N-[(3S)-3-ethylsulfonylbutan-2-ylidene]hydroxylamine
    —— (NZ)-N-(1-ethylsulfonyl-3,3-dimethylbutan-2-ylidene)hydroxylamine —— C8H17NO3S
    (NZ)-N-(1-ethylsulfonyl-3,3-dimethylbutan-2-ylidene)hydroxylamine
    —— (NZ)-N-[(4S)-2,2-dimethyl-4-methylsulfonylhexan-3-ylidene]hydroxylamine —— C9H19NO3S
    (NZ)-N-[(4S)-2,2-dimethyl-4-methylsulfonylhexan-3-ylidene]hydroxylamine
    —— N-[(1S)-1-(2,4-difluorophenyl)ethyl]-2-phenylsulfanylacetamide —— C16H15F2NOS
    N-[(1S)-1-(2,4-difluorophenyl)ethyl]-2-phenylsulfanylacetamide
    —— (NZ)-N-[(2S)-1-cyclopropyl-2-methylsulfonylpropylidene]hydroxylamine —— C7H13NO3S
    (NZ)-N-[(2S)-1-cyclopropyl-2-methylsulfonylpropylidene]hydroxylamine
    —— (NZ)-N-[(4S)-4-ethylsulfonyl-2,2-dimethylpentan-3-ylidene]hydroxylamine —— C9H19NO3S
    (NZ)-N-[(4S)-4-ethylsulfonyl-2,2-dimethylpentan-3-ylidene]hydroxylamine
    —— (NZ)-N-[(2R)-1-cyclopropyl-2-methylsulfonylbutylidene]hydroxylamine —— C8H15NO3S
    (NZ)-N-[(2R)-1-cyclopropyl-2-methylsulfonylbutylidene]hydroxylamine
    —— (NE)-N-(1-cyclopropyl-2-methylsulfonylethylidene)hydroxylamine —— C6H11NO3S
    (NE)-N-(1-cyclopropyl-2-methylsulfonylethylidene)hydroxylamine
    —— (NZ)-N-[(4S)-2,2-dimethyl-4-methylsulfonylpentan-3-ylidene]hydroxylamine —— C8H17NO3S
    (NZ)-N-[(4S)-2,2-dimethyl-4-methylsulfonylpentan-3-ylidene]hydroxylamine
    —— (NZ)-N-[(3S)-3-methylsulfonylpentan-2-ylidene]hydroxylamine —— C6H13NO3S
    (NZ)-N-[(3S)-3-methylsulfonylpentan-2-ylidene]hydroxylamine
    —— (2S)-N-[2-(4-fluorophenyl)ethyl]-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C20H21FN4OS2
    (2S)-N-[2-(4-fluorophenyl)ethyl]-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-phenylethyl]acetamide —— C18H20N4O2S
    2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-phenylethyl]acetamide
    —— 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-phenylethyl]acetamide —— C18H20N4O2S
    2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-phenylethyl]acetamide
    —— (2R,3Z)-3-hydroxyimino-4,4-dimethyl-2-methylsulfonylpentan-1-ol —— C8H17NO4S
    (2R,3Z)-3-hydroxyimino-4,4-dimethyl-2-methylsulfonylpentan-1-ol
    —— (NZ)-N-[(3R)-3-methylsulfonylpentan-2-ylidene]hydroxylamine —— C6H13NO3S
    (NZ)-N-[(3R)-3-methylsulfonylpentan-2-ylidene]hydroxylamine
    —— (NZ)-N-[(2S)-1-cyclopropyl-2-methylsulfonylbutylidene]hydroxylamine —— C8H15NO3S
    (NZ)-N-[(2S)-1-cyclopropyl-2-methylsulfonylbutylidene]hydroxylamine
    —— N-methyl-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(thiophen-2-ylmethyl)acetamide —— C17H18N4OS3
    N-methyl-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(thiophen-2-ylmethyl)acetamide
    —— 2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-thiophen-2-ylethyl]acetamide —— C17H18N4OS3
    2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-thiophen-2-ylethyl]acetamide
    —— (2R)-N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C18H23N5OS2
    (2R)-N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— (2R)-1-(4-ethylpiperazin-1-yl)-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propan-1-one —— C18H25N5OS2
    (2R)-1-(4-ethylpiperazin-1-yl)-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]propan-1-one
    —— 3-(4-chlorophenyl)sulfanyl-N-[(1R)-1-(2,4-difluorophenyl)ethyl]propanamide —— C17H16ClF2NOS
    3-(4-chlorophenyl)sulfanyl-N-[(1R)-1-(2,4-difluorophenyl)ethyl]propanamide
    —— 1-[[2-(4-Bromophenyl)sulfanylacetyl]amino]-3-pentylthiourea —— C14H20BrN3OS2
    1-[[2-(4-Bromophenyl)sulfanylacetyl]amino]-3-pentylthiourea
    —— (1R,2R)-N'-hydroxy-2-methyl-1-methylsulfonylcyclopropane-1-carboximidamide —— C6H12N2O3S
    (1R,2R)-N'-hydroxy-2-methyl-1-methylsulfonylcyclopropane-1-carboximidamide
    —— (NE)-N-(1-cyclopropyl-2-ethylsulfonylethylidene)hydroxylamine —— C7H13NO3S
    (NE)-N-(1-cyclopropyl-2-ethylsulfonylethylidene)hydroxylamine
    —— N-[(1S)-1-(2-bromophenyl)ethyl]-3-(4-fluorophenyl)sulfanylpropanamide —— C17H17BrFNOS
    N-[(1S)-1-(2-bromophenyl)ethyl]-3-(4-fluorophenyl)sulfanylpropanamide