摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-[4-(4-Chloro-2-methylanilino)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide —— C16H15ClN4S3
    4-[4-(4-Chloro-2-methylanilino)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
    —— 2-[4-[1-(1-Cyclohexylpiperidin-4-yl)ethenyl]phenyl]sulfanylpyridine —— C24H30N2S
    2-[4-[1-(1-Cyclohexylpiperidin-4-yl)ethenyl]phenyl]sulfanylpyridine
    —— 4-[[(2R,4R)-4-(4-hydroxyphenyl)sulfanylpyrrolidin-2-yl]methylsulfanyl]phenol —— C17H19NO2S2
    4-[[(2R,4R)-4-(4-hydroxyphenyl)sulfanylpyrrolidin-2-yl]methylsulfanyl]phenol
    —— (2S,4R)-4-[3-fluoro-5-[4-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenyl]sulfanylphenyl]-2-methyloxan-4-ol —— C20H22FNO3S
    (2S,4R)-4-[3-fluoro-5-[4-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenyl]sulfanylphenyl]-2-methyloxan-4-ol
    —— 2-[(2-Amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]butan-1-ol —— C16H19N5OS2
    2-[(2-Amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]butan-1-ol
    —— N-[3-(tert-butyl)pyrazol-5-yl][(4-(4-pyridylthio)phenyl)amino]carboxamide —— C19H21N5OS
    N-[3-(tert-butyl)pyrazol-5-yl][(4-(4-pyridylthio)phenyl)amino]carboxamide
    —— 5-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)propylsulfanyl]-1,3,4-thiadiazol-2-amine;hydrochloride —— C16H21ClN4S2
    5-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)propylsulfanyl]-1,3,4-thiadiazol-2-amine;hydrochloride
    —— 4-[2-[2-[(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethoxy]ethylsulfanyl]phenol —— C13H16N2O2S4
    4-[2-[2-[(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethoxy]ethylsulfanyl]phenol
    —— 3-(4-chloro-anilino)-5-(3,4-difluoro-benzylthio)-1,2,4-triazole 334539-39-8 C15H11ClF2N4S
    3-(4-chloro-anilino)-5-(3,4-difluoro-benzylthio)-1,2,4-triazole
    —— (Z,Z)-2-bromo-N-(3-methyl-5-methylsulfanyl-1,2,4-triazol-4-yl)-3-phenylprop-2-en-1-imine —— C13H13BrN4S
    (Z,Z)-2-bromo-N-(3-methyl-5-methylsulfanyl-1,2,4-triazol-4-yl)-3-phenylprop-2-en-1-imine
    —— N7-Cyclopropyl-5-(pentylthio)thiazolo[4,5-d]pyrimidine-2,7-diamine 259100-75-9 C13H19N5S2
    N7-Cyclopropyl-5-(pentylthio)thiazolo[4,5-d]pyrimidine-2,7-diamine
    —— 4-[(4-methylphenyl)thio]thieno[3,2-c]pyridine-2-carboxamide —— C15H12N2OS2
    4-[(4-methylphenyl)thio]thieno[3,2-c]pyridine-2-carboxamide
    —— 3-anilino-5-(5-methyl-isoxazol-3-ylmethylthio)-1,2,4-triazole 334538-61-3 C13H13N5OS
    3-anilino-5-(5-methyl-isoxazol-3-ylmethylthio)-1,2,4-triazole
    —— 8-benzyl-5-methyl-3,4-dihydro-2H-pyridazino[4,5-b][1,4]thiazepin-9-one —— C15H17N3OS
    8-benzyl-5-methyl-3,4-dihydro-2H-pyridazino[4,5-b][1,4]thiazepin-9-one
    —— 3-(3-(4-Cyanobutylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine —— C13H18N4S2
    3-(3-(4-Cyanobutylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine
    —— 2-(4-Phenylsulfanylanilino)thieno[2,3-d][1,3]oxazin-4-one —— C18H12N2O2S2
    2-(4-Phenylsulfanylanilino)thieno[2,3-d][1,3]oxazin-4-one
    —— 4-Isopropyl-2-methyl-5-phenylthio-1-[(4-pyridyl)methyl]-1H-pyrrole-3-methanol —— C21H24N2OS
    4-Isopropyl-2-methyl-5-phenylthio-1-[(4-pyridyl)methyl]-1H-pyrrole-3-methanol
    —— (5R,6R)-6-(3-(3-(2-thienyl)propylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane —— C16H21N3S3
    (5R,6R)-6-(3-(3-(2-thienyl)propylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane
    —— 4-(3-ethylsulfanyl-5-methyl-1,2-oxazol-4-yl)-N-(4-fluorophenyl)pyrimidin-2-amine —— C16H15FN4OS
    4-(3-ethylsulfanyl-5-methyl-1,2-oxazol-4-yl)-N-(4-fluorophenyl)pyrimidin-2-amine
    —— 6-acetyl-2-[(1R,3S)-3-amino-4-hydroxy-1-phenylbutyl]sulfanylpyridine-3-carbonitrile —— C18H19N3O2S
    6-acetyl-2-[(1R,3S)-3-amino-4-hydroxy-1-phenylbutyl]sulfanylpyridine-3-carbonitrile
    —— 4-(2-Anilinopyridin-4-yl)-3-methyl-5-methylsulfanylthiophene-2-carbonitrile —— C18H15N3S2
    4-(2-Anilinopyridin-4-yl)-3-methyl-5-methylsulfanylthiophene-2-carbonitrile
    —— 3-[(1R,3S)-3-amino-4-hydroxy-1-phenylbutyl]sulfanyl-5-methyl-6-oxo-1H-pyridine-2-carbonitrile —— C17H19N3O2S
    3-[(1R,3S)-3-amino-4-hydroxy-1-phenylbutyl]sulfanyl-5-methyl-6-oxo-1H-pyridine-2-carbonitrile
    —— 2-(4-Chlorophenyl)-5-(1-oxidopyridin-1-ium-2-yl)sulfanyl-1,2-thiazol-3-one —— C14H9ClN2O2S2
    2-(4-Chlorophenyl)-5-(1-oxidopyridin-1-ium-2-yl)sulfanyl-1,2-thiazol-3-one
    —— exo-6-(3-(4-methylbenzylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane —— C17H21N3S2
    exo-6-(3-(4-methylbenzylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane
    —— N-[(1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-yl]-5-(phenylsulfanyl)-thiophene-2-carboxamide 500605-54-9 C17H18N2OS2
    N-[(1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-yl]-5-(phenylsulfanyl)-thiophene-2-carboxamide
    —— 2-[(1R,3S)-3-amino-4-methoxy-1-phenylbutyl]sulfanyl-6-methylpyridine-3-carbonitrile —— C18H21N3OS
    2-[(1R,3S)-3-amino-4-methoxy-1-phenylbutyl]sulfanyl-6-methylpyridine-3-carbonitrile
    —— 3-(6-Pyridin-4-ylsulfanylpyridin-3-yl)-3,10-diazabicyclo[4.3.1]decane —— C18H22N4S
    3-(6-Pyridin-4-ylsulfanylpyridin-3-yl)-3,10-diazabicyclo[4.3.1]decane
    —— N-(2-propan-2-ylphenyl)-3-thiophen-2-ylsulfanyl-1H-1,2,4-triazol-5-amine —— C15H16N4S2
    N-(2-propan-2-ylphenyl)-3-thiophen-2-ylsulfanyl-1H-1,2,4-triazol-5-amine
    —— 7-fluoro-9-(4-methyl-1-piperazinyl)pyrrolo[2,1-b][1,3]benzothiazepine —— C17H18FN3S
    7-fluoro-9-(4-methyl-1-piperazinyl)pyrrolo[2,1-b][1,3]benzothiazepine
    —— (1R,2R)-N-(cyanomethyl)-2-{[(3-hydroxyphenyl)sulfanyl]methyl}cyclohexane-1-carboxamide —— C16H20N2O2S
    (1R,2R)-N-(cyanomethyl)-2-{[(3-hydroxyphenyl)sulfanyl]methyl}cyclohexane-1-carboxamide
    —— 5-[(2-methylphenyl)methyl]-3-(thiophen-2-ylmethylsulfanyl)-1H-1,2,4-triazole —— C15H15N3S2
    5-[(2-methylphenyl)methyl]-3-(thiophen-2-ylmethylsulfanyl)-1H-1,2,4-triazole
    —— (3R)-3-(5-chloro-2-methoxypyridin-4-yl)sulfanyl-3-(1,2-oxazol-5-yl)propan-1-amine —— C12H14ClN3O2S
    (3R)-3-(5-chloro-2-methoxypyridin-4-yl)sulfanyl-3-(1,2-oxazol-5-yl)propan-1-amine
    —— 2-[4-Amino-1-(1,2-oxazol-5-yl)butyl]sulfanyl-6-methylpyridine-3-carbonitrile —— C14H16N4OS
    2-[4-Amino-1-(1,2-oxazol-5-yl)butyl]sulfanyl-6-methylpyridine-3-carbonitrile
    —— 2-[[3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazol-5-yl]methyl]pyridine —— C14H14N4S2
    2-[[3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazol-5-yl]methyl]pyridine
    —— (Z)-N-[(5-propylsulfanylthiadiazol-4-yl)methoxy]-1-azabicyclo[2.2.1]heptan-3-imine —— C12H18N4OS2
    (Z)-N-[(5-propylsulfanylthiadiazol-4-yl)methoxy]-1-azabicyclo[2.2.1]heptan-3-imine
    —— 3-[[4-(thiadiazol-5-yl)phenyl]methylsulfanyl]-1H-1,2,4-triazol-5-amine —— C11H10N6S2
    3-[[4-(thiadiazol-5-yl)phenyl]methylsulfanyl]-1H-1,2,4-triazol-5-amine
    —— (1R,2R)-2-[(4-chlorophenyl)sulfanylmethyl]-N-(cyanomethyl)cyclopentane-1-carboxamide —— C15H17ClN2OS
    (1R,2R)-2-[(4-chlorophenyl)sulfanylmethyl]-N-(cyanomethyl)cyclopentane-1-carboxamide
    —— 6-(5,5-Dimethyl-6-oxohexyl)sulfanyl-2,2-dimethylhexanal —— C16H30O2S
    6-(5,5-Dimethyl-6-oxohexyl)sulfanyl-2,2-dimethylhexanal
    —— 3-[(3S)-1-azabicyclo[2.2.1]heptan-3-yl]-4-pentylsulfanyl-1,2,5-thiadiazole —— C13H21N3S2
    3-[(3S)-1-azabicyclo[2.2.1]heptan-3-yl]-4-pentylsulfanyl-1,2,5-thiadiazole
    —— (4-amino-5-cyclopropylmethyl-pyrimidin-2-yl-sulfanyl)-acetic acid ethyl ester 476302-33-7 C12H17N3O2S
    (4-amino-5-cyclopropylmethyl-pyrimidin-2-yl-sulfanyl)-acetic acid ethyl ester
    —— 2-[4-(4-Chlorophenyl)sulfanyl-3,5-dimethylpyrazol-1-yl]ethanol —— C13H15ClN2OS
    2-[4-(4-Chlorophenyl)sulfanyl-3,5-dimethylpyrazol-1-yl]ethanol
    —— 3-Amino-1-chloro-4-phenylsulfanylbutan-2-one —— C10H12ClNOS
    3-Amino-1-chloro-4-phenylsulfanylbutan-2-one
    —— 1-Cyclopentylmethyl-3-(2-hydroxy-ethyl)-thiourea —— C9H18N2OS
    1-Cyclopentylmethyl-3-(2-hydroxy-ethyl)-thiourea
    —— 5-ethynylsulfanyl-3H-1,3,4-thiadiazole-2-thione —— C4H2N2S3
    5-ethynylsulfanyl-3H-1,3,4-thiadiazole-2-thione
    —— 3-[[(4R,9R,14R,19R)-3,10,13,20,26-pentazatetracyclo[20.3.1.04,9.014,19]hexacosa-1(25),22(26),23-trien-24-yl]sulfanyl]propan-1-ol —— C24H41N5OS
    3-[[(4R,9R,14R,19R)-3,10,13,20,26-pentazatetracyclo[20.3.1.04,9.014,19]hexacosa-1(25),22(26),23-trien-24-yl]sulfanyl]propan-1-ol
    —— (Z,Z)-2-bromo-3-phenyl-N-[3-(2-phenylethyl)-5-(2-phenylethylsulfanyl)-1,2,4-triazol-4-yl]prop-2-en-1-imine —— C27H25BrN4S
    (Z,Z)-2-bromo-3-phenyl-N-[3-(2-phenylethyl)-5-(2-phenylethylsulfanyl)-1,2,4-triazol-4-yl]prop-2-en-1-imine
    —— 2-[(1-benzyl-2-oxopyridin-4-yl)methyl]-5-(8-phenyloctylsulfanyl)-1H-pyrimidin-6-one —— C31H35N3O2S
    2-[(1-benzyl-2-oxopyridin-4-yl)methyl]-5-(8-phenyloctylsulfanyl)-1H-pyrimidin-6-one
    —— 2-[5-[[2-[(4-fluorophenyl)methylsulfanyl]-1-methyl-4-oxopyrimidin-5-yl]methyl]-2-oxopyrimidin-1-yl]-N-(2-methoxyethyl)-N-methylacetamide —— C23H26FN5O4S
    2-[5-[[2-[(4-fluorophenyl)methylsulfanyl]-1-methyl-4-oxopyrimidin-5-yl]methyl]-2-oxopyrimidin-1-yl]-N-(2-methoxyethyl)-N-methylacetamide
    —— N-{4-[3-(4-Fluorophenylsulfamoyl)-4-hydroxyphenylsulfanyl]-3,5-dimethylphenyl}-oxamic acid —— C22H19FN2O6S2
    N-{4-[3-(4-Fluorophenylsulfamoyl)-4-hydroxyphenylsulfanyl]-3,5-dimethylphenyl}-oxamic acid
    —— 2-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-yl)-N-[(4-phenylsulfanylphenyl)methyl]acetamide —— C25H22N2O2S3
    2-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-yl)-N-[(4-phenylsulfanylphenyl)methyl]acetamide