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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-1-pyridin-3-ylethylideneamino]acetamide —— C15H14ClN3OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-1-pyridin-3-ylethylideneamino]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-furan-2-ylmethylideneamino]acetamide —— C13H11ClN2O2S
    2-(4-chlorophenyl)sulfanyl-N-[(E)-furan-2-ylmethylideneamino]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(3-fluorophenyl)methylideneamino]acetamide —— C15H12ClFN2OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(3-fluorophenyl)methylideneamino]acetamide
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-methylthiophen-2-yl)methanimine —— C15H13ClN4S2
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-methylthiophen-2-yl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-methyl-1,3-thiazol-4-yl)methanimine —— C14H12ClN5S2
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-methyl-1,3-thiazol-4-yl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4,6-trimethylphenyl)methanimine —— C19H19ClN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4,6-trimethylphenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4-dimethylphenyl)methanimine —— C18H17ClN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4-dimethylphenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3-fluorophenyl)methanimine —— C16H12ClFN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3-fluorophenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4-difluorophenyl)methanimine —— C16H11ClF2N4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,4-difluorophenyl)methanimine
    —— (2R)-2-amino-2-(2-methylsulfanylpyrimidin-4-yl)ethanol —— C7H11N3OS
    (2R)-2-amino-2-(2-methylsulfanylpyrimidin-4-yl)ethanol
    —— (NZ)-N-[1-[2-[5-amino-6-(dimethylamino)pyrimidin-4-yl]sulfanyl-5-nitrophenyl]ethylidene]hydroxylamine —— C14H16N6O3S
    (NZ)-N-[1-[2-[5-amino-6-(dimethylamino)pyrimidin-4-yl]sulfanyl-5-nitrophenyl]ethylidene]hydroxylamine
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-1-pyridin-3-ylethylideneamino]acetamide —— C15H14FN3OS
    2-(2-fluorophenyl)sulfanyl-N-[(E)-1-pyridin-3-ylethylideneamino]acetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide —— C14H13FN2OS2
    2-(2-fluorophenyl)sulfanyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-1-(furan-2-yl)ethylideneamino]acetamide —— C14H13FN2O2S
    2-(2-fluorophenyl)sulfanyl-N-[(E)-1-(furan-2-yl)ethylideneamino]acetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-thiophen-2-ylmethylideneamino]acetamide —— C13H11FN2OS2
    2-(2-fluorophenyl)sulfanyl-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
    —— N-[(E)-(2-bromophenyl)methylideneamino]-2-(2-fluorophenyl)sulfanylacetamide —— C15H12BrFN2OS
    N-[(E)-(2-bromophenyl)methylideneamino]-2-(2-fluorophenyl)sulfanylacetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-pyridin-4-ylmethylideneamino]acetamide —— C14H12FN3OS
    2-(2-fluorophenyl)sulfanyl-N-[(E)-pyridin-4-ylmethylideneamino]acetamide
    —— N-[(E)-(2-fluorophenyl)methylideneamino]-2-(2-fluorophenyl)sulfanylacetamide —— C15H12F2N2OS
    N-[(E)-(2-fluorophenyl)methylideneamino]-2-(2-fluorophenyl)sulfanylacetamide
    —— 1-[(E)-(4-methylsulfanylphenyl)methylideneamino]-3-(2-morpholin-4-ylethyl)thiourea —— C15H22N4OS2
    1-[(E)-(4-methylsulfanylphenyl)methylideneamino]-3-(2-morpholin-4-ylethyl)thiourea
    —— 2-(2-fluorophenyl)sulfanyl-N-[(E)-[4-[2-hydroxyethyl(methyl)amino]phenyl]methylideneamino]acetamide —— C18H20FN3O2S
    2-(2-fluorophenyl)sulfanyl-N-[(E)-[4-[2-hydroxyethyl(methyl)amino]phenyl]methylideneamino]acetamide
    —— 1-[4-(difluoromethylsulfanyl)phenyl]-3-[(E)-1-(5-methylfuran-2-yl)ethylideneamino]thiourea —— C15H15F2N3OS2
    1-[4-(difluoromethylsulfanyl)phenyl]-3-[(E)-1-(5-methylfuran-2-yl)ethylideneamino]thiourea
    —— N-[(E)-(3-bromophenyl)methylideneamino]-3-[(3-methylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine —— C17H16BrN5S
    N-[(E)-(3-bromophenyl)methylideneamino]-3-[(3-methylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine
    —— N-cyclopropyl-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C12H14N6O2S
    N-cyclopropyl-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 3-[(2-chlorophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine —— C14H12ClN5OS
    3-[(2-chlorophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine
    —— 3-[(3-bromophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine —— C14H12BrN5OS
    3-[(3-bromophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine
    —— 2-[[5-[(2E)-2-benzylidenehydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C11H12N6OS
    2-[[5-[(2E)-2-benzylidenehydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 1-(2,6-dimethylphenyl)-3-[(E)-(4-methylsulfanylphenyl)methylideneamino]thiourea —— C17H19N3S2
    1-(2,6-dimethylphenyl)-3-[(E)-(4-methylsulfanylphenyl)methylideneamino]thiourea
    —— N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine —— C16H22N6S
    N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-[(E)-benzylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C13H17N5S
    N-[(E)-benzylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— 2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetonitrile —— C15H19N7S
    2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetonitrile
    —— 2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]-N-tert-butylacetamide —— C15H19BrN6OS
    2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]-N-tert-butylacetamide
    —— N-[(E)-furan-2-ylmethylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C11H15N5OS
    N-[(E)-furan-2-ylmethylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine —— C14H20N6S
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-tert-butyl-2-[[5-[(2E)-2-[[4-(dimethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C17H25N7OS
    N-tert-butyl-2-[[5-[(2E)-2-[[4-(dimethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 4-methyl-2-[(2E)-2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]-1H-pyrimidin-6-one —— C13H14N4OS
    4-methyl-2-[(2E)-2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]-1H-pyrimidin-6-one
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylphenyl)methanimine —— C17H16N4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylphenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine —— C16H15N5S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-3-ylmethanimine —— C16H15N5S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-3-ylmethanimine
    —— 3-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]phenol —— C17H16N4OS
    3-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]phenol
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2,3,6-trichlorophenyl)methanimine —— C16H11Cl3N4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2,3,6-trichlorophenyl)methanimine
    —— 4-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]-N,N-dimethylaniline —— C19H21N5S
    4-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]-N,N-dimethylaniline
    —— 3-[(E)-(3-benzylsulfanyl-1,2,4-triazol-4-yl)iminomethyl]phenol —— C16H14N4OS
    3-[(E)-(3-benzylsulfanyl-1,2,4-triazol-4-yl)iminomethyl]phenol
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine —— C17H15BrN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-chlorophenyl)methanimine —— C17H15ClN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-chlorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-thiophen-2-ylmethanimine —— C14H12N4S2
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-thiophen-2-ylmethanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-fluorophenyl)methanimine —— C17H15FN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-fluorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-fluorophenyl)methanimine —— C17H15FN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-fluorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine —— C16H16N4S2
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine
    —— (E,Z)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine —— C20H20N4S
    (E,Z)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine —— C17H16N4S2
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine