摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (4-amino-5-benzyl-pyrimidin-2-ylsulfanyl)-acetic acid 5-methyl-isoxazol-3-ylmethyl ester 476302-29-1 C18H18N4O3S
    (4-amino-5-benzyl-pyrimidin-2-ylsulfanyl)-acetic acid 5-methyl-isoxazol-3-ylmethyl ester
    —— (3E)-6-methyl-3-[7-(5-methylsulfanylthiophen-2-yl)-1,4-thiazepan-5-ylidene]pyran-2,4-dione —— C16H17NO3S3
    (3E)-6-methyl-3-[7-(5-methylsulfanylthiophen-2-yl)-1,4-thiazepan-5-ylidene]pyran-2,4-dione
    —— 4-(3-ethylsulfanyl-5-methyl-1,2-oxazol-4-yl)-N-(4-methylsulfanylphenyl)pyrimidin-2-amine —— C17H18N4OS2
    4-(3-ethylsulfanyl-5-methyl-1,2-oxazol-4-yl)-N-(4-methylsulfanylphenyl)pyrimidin-2-amine
    —— 2-[4-[(3,5-dichlorophenyl)sulfanyl]-3-ethyl-5-(hydroxymethyl)-1H-pyrazol-1-yl]ethanol —— C14H16Cl2N2O2S
    2-[4-[(3,5-dichlorophenyl)sulfanyl]-3-ethyl-5-(hydroxymethyl)-1H-pyrazol-1-yl]ethanol
    —— (2S)-2-(3-bromopyridin-2-yl)sulfanyl-N,N-dimethylpropanamide —— C10H13BrN2OS
    (2S)-2-(3-bromopyridin-2-yl)sulfanyl-N,N-dimethylpropanamide
    —— [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-(1,4-thiazepan-4-yl)methanone —— C14H17NOS2
    [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-(1,4-thiazepan-4-yl)methanone
    —— (3R)-N-methyl-N-(pyridin-2-ylmethyl)-2,3-dihydro-1-benzothiophene-3-carboxamide —— C16H16N2OS
    (3R)-N-methyl-N-(pyridin-2-ylmethyl)-2,3-dihydro-1-benzothiophene-3-carboxamide
    —— (2R)-2-(3-bromopyridin-2-yl)sulfanyl-N,N-dimethylpropanamide —— C10H13BrN2OS
    (2R)-2-(3-bromopyridin-2-yl)sulfanyl-N,N-dimethylpropanamide
    —— [5-(3,5-Dichlorophenyl)sulfanyl-4-ethyl-1-propan-2-ylpyrazol-3-yl]methanol —— C15H18Cl2N2OS
    [5-(3,5-Dichlorophenyl)sulfanyl-4-ethyl-1-propan-2-ylpyrazol-3-yl]methanol
    —— 5-[(4-chlorophenyl)methyl]-3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole —— C15H14ClN3S2
    5-[(4-chlorophenyl)methyl]-3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole
    —— (3S)-N-methyl-N-(pyridin-2-ylmethyl)-2,3-dihydro-1-benzothiophene-3-carboxamide —— C16H16N2OS
    (3S)-N-methyl-N-(pyridin-2-ylmethyl)-2,3-dihydro-1-benzothiophene-3-carboxamide
    —— [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-(1,4-thiazepan-4-yl)methanone —— C14H17NOS2
    [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-(1,4-thiazepan-4-yl)methanone
    —— (5R)-5-(thiophen-2-ylsulfanylmethyl)-1,3-oxazolidin-2-one —— C8H9NO2S2
    (5R)-5-(thiophen-2-ylsulfanylmethyl)-1,3-oxazolidin-2-one
    —— (3R)-3-(2,4-dimethylphenyl)sulfanyl-1-methylpyrrolidin-2-one —— C13H17NOS
    (3R)-3-(2,4-dimethylphenyl)sulfanyl-1-methylpyrrolidin-2-one
    —— (5S)-5-(thiophen-2-ylsulfanylmethyl)-1,3-oxazolidin-2-one —— C8H9NO2S2
    (5S)-5-(thiophen-2-ylsulfanylmethyl)-1,3-oxazolidin-2-one
    —— 4-[[3-[(4-fluorophenyl)methylsulfanyl]-1H-1,2,4-triazol-5-yl]methyl]-N,N-dimethylaniline —— C18H19FN4S
    4-[[3-[(4-fluorophenyl)methylsulfanyl]-1H-1,2,4-triazol-5-yl]methyl]-N,N-dimethylaniline
    —— (3S)-3-(2,4-dimethylphenyl)sulfanyl-1-methylpyrrolidin-2-one —— C13H17NOS
    (3S)-3-(2,4-dimethylphenyl)sulfanyl-1-methylpyrrolidin-2-one
    —— 1,1,1-Trifluoropropan-2-yl 2-(4-pyrazol-1-ylpyrimidin-2-yl)sulfanylacetate —— C12H11F3N4O2S
    1,1,1-Trifluoropropan-2-yl 2-(4-pyrazol-1-ylpyrimidin-2-yl)sulfanylacetate
    —— 5-[2-(5-Hydroxy-4,4-dimethylpentyl)sulfanylethylsulfanyl]-2,2-dimethylpentan-1-ol —— C16H34O2S2
    5-[2-(5-Hydroxy-4,4-dimethylpentyl)sulfanylethylsulfanyl]-2,2-dimethylpentan-1-ol
    —— exo-6-(3-(2-(1,3-dioxolan-2-yl)-ethylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane —— C14H21N3O2S2
    exo-6-(3-(2-(1,3-dioxolan-2-yl)-ethylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane
    —— 3-[(3R)-1-azabicyclo[2.2.1]heptan-3-yl]-4-(3-phenylpropylsulfanyl)-1,2,5-thiadiazole —— C17H21N3S2
    3-[(3R)-1-azabicyclo[2.2.1]heptan-3-yl]-4-(3-phenylpropylsulfanyl)-1,2,5-thiadiazole
    —— 1-[2-[2-(4-Methoxyphenyl)sulfanylphenyl]ethyl]imidazol-2-amine —— C18H19N3OS
    1-[2-[2-(4-Methoxyphenyl)sulfanylphenyl]ethyl]imidazol-2-amine
    —— 5-[(3-methylphenyl)methyl]-3-[(5-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole —— C16H17N3S2
    5-[(3-methylphenyl)methyl]-3-[(5-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole
    —— N-(4-fluorophenyl)-4-(5-methyl-3-methylsulfanyl-1,2-oxazol-4-yl)pyrimidin-2-amine —— C15H13FN4OS
    N-(4-fluorophenyl)-4-(5-methyl-3-methylsulfanyl-1,2-oxazol-4-yl)pyrimidin-2-amine
    —— 5-[(3-methylphenyl)methyl]-3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole —— C16H17N3S2
    5-[(3-methylphenyl)methyl]-3-[(3-methylthiophen-2-yl)methylsulfanyl]-1H-1,2,4-triazole
    —— 4-[2-[2-(2-Aminoimidazol-1-yl)ethyl]phenyl]sulfanylphenol —— C17H17N3OS
    4-[2-[2-(2-Aminoimidazol-1-yl)ethyl]phenyl]sulfanylphenol
    —— 4-methylthio-3-(5-methylisoxazol-3-yl)-2-ethylbromobenzene 391200-02-5 C13H14BrNOS
    4-methylthio-3-(5-methylisoxazol-3-yl)-2-ethylbromobenzene
    —— 5-[(4-chlorophenyl)methyl]-3-(furan-2-ylmethylsulfanyl)-1H-1,2,4-triazole —— C14H12ClN3OS
    5-[(4-chlorophenyl)methyl]-3-(furan-2-ylmethylsulfanyl)-1H-1,2,4-triazole
    —— 4-Isopropyl-2-methyl-5-methylthio-1-[(4-pyridyl)methyl]-1H-pyrrole-3-methanol —— C16H22N2OS
    4-Isopropyl-2-methyl-5-methylthio-1-[(4-pyridyl)methyl]-1H-pyrrole-3-methanol
    —— 3-(benzylthio)-5-(2-methylbenzyl)-4H-1,2,4-triazole —— C17H17N3S
    3-(benzylthio)-5-(2-methylbenzyl)-4H-1,2,4-triazole
    —— (1R,2R)-N-(cyanomethyl)-2-[(4-fluorophenyl)sulfanylmethyl]cyclopentane-1-carboxamide —— C15H17FN2OS
    (1R,2R)-N-(cyanomethyl)-2-[(4-fluorophenyl)sulfanylmethyl]cyclopentane-1-carboxamide
    —— 4-Hydroxy-4-phenyl-5-phenylsulfanylcyclohex-2-en-1-one —— C18H16O2S
    4-Hydroxy-4-phenyl-5-phenylsulfanylcyclohex-2-en-1-one
    —— 4-(2-[4-chloro-phenylsulfanyl]-phenyl)-1H-1,2,3-triazole 369363-82-6 C14H10ClN3S
    4-(2-[4-chloro-phenylsulfanyl]-phenyl)-1H-1,2,3-triazole
    —— 3-[(S)-octylsulfinyl]propan-1-ol —— C11H24O2S
    3-[(S)-octylsulfinyl]propan-1-ol
    —— 1-[(S)-2-chloroethylsulfinyl]decane —— C12H25ClOS
    1-[(S)-2-chloroethylsulfinyl]decane
    —— 4-[(R)-octylsulfinyl]butan-1-ol —— C12H26O2S
    4-[(R)-octylsulfinyl]butan-1-ol
    —— 1-[(2R)-2,3-dichloropropyl]sulfonyloctane —— C11H22Cl2O2S
    1-[(2R)-2,3-dichloropropyl]sulfonyloctane
    —— 1-[(R)-2-chloroethylsulfinyl]decane —— C12H25ClOS
    1-[(R)-2-chloroethylsulfinyl]decane
    —— 1-[(2S)-2,3-dichloropropyl]sulfonyloctane —— C11H22Cl2O2S
    1-[(2S)-2,3-dichloropropyl]sulfonyloctane
    —— 3-[(R)-octylsulfinyl]propan-1-ol —— C11H24O2S
    3-[(R)-octylsulfinyl]propan-1-ol
    —— 4-Chloro-6-(cyclopropylmethyl-amino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde 444605-26-9 C10H12ClN3OS
    4-Chloro-6-(cyclopropylmethyl-amino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde
    —— methyl (E)-4-methoxy-3-phenylsulfanylbut-2-enoate —— C12H14O3S
    methyl (E)-4-methoxy-3-phenylsulfanylbut-2-enoate
    —— methyl (E)-6-cyano-3-phenylsulfanylhex-2-enoate —— C14H15NO2S
    methyl (E)-6-cyano-3-phenylsulfanylhex-2-enoate
    —— 6-Methyl-2-[5-(methylamino)pent-1-en-3-ylsulfanyl]pyridine-3-carbonitrile —— C13H17N3S
    6-Methyl-2-[5-(methylamino)pent-1-en-3-ylsulfanyl]pyridine-3-carbonitrile
    —— (4S)-2-amino-4-(4-bromothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C21H22BrN5OS3
    (4S)-2-amino-4-(4-bromothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile
    —— (4R)-2-amino-4-(4-bromothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C21H22BrN5OS3
    (4R)-2-amino-4-(4-bromothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile
    —— (4S)-2-amino-4-(3,5-dichlorothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C21H21Cl2N5OS3
    (4S)-2-amino-4-(3,5-dichlorothiophen-2-yl)-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile
    —— (4R)-2-amino-4-[5-(2-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C27H26ClN5O2S2
    (4R)-2-amino-4-[5-(2-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile
    —— (4S)-2-amino-4-[5-(3-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C27H26ClN5O2S2
    (4S)-2-amino-4-[5-(3-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile
    —— (4S)-2-amino-4-[5-(2-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile —— C27H26ClN5O2S2
    (4S)-2-amino-4-[5-(2-chlorophenyl)furan-2-yl]-7,7-dimethyl-5-oxo-1-(5-propan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-4H-quinoline-3-carbonitrile