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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3O2S
    (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3OS2
    (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— 2-methoxy-N-[(E)-(5-quinolin-8-ylsulfanylfuran-2-yl)methylideneamino]acetamide —— C17H15N3O3S
    2-methoxy-N-[(E)-(5-quinolin-8-ylsulfanylfuran-2-yl)methylideneamino]acetamide
    —— (2R)-3-[(4-cyclopropyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1,1,1-trifluoropropan-2-ol —— C11H16F3N3OS
    (2R)-3-[(4-cyclopropyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1,1,1-trifluoropropan-2-ol
    —— (2R)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol —— C8H12F3N3OS
    (2R)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol
    —— (2S)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol —— C8H12F3N3OS
    (2S)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol
    —— (5R)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one —— C13H13N3O2S
    (5R)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one
    —— (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3OS2
    (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— (5S)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one —— C13H13N3O2S
    (5S)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one
    —— 2,3,5,6-tetrafluoro-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-4-amine —— C13H9F4N3S
    2,3,5,6-tetrafluoro-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-4-amine
    —— (2R)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C10H18N4OS
    (2R)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C8H14N4OS
    (2S)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C10H18N4OS
    (2S)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one —— C12H20N4OS
    (2S)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one
    —— (2R)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C8H14N4OS
    (2R)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2R)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one —— C12H20N4OS
    (2R)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one
    —— (2R)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile —— C14H13N3OS2
    (2R)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile
    —— (2S)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile —— C14H13N3OS2
    (2S)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile
    —— (2R)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2R)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— (2S)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2S)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— (2R)-N-[(1R)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2R)-N-[(1R)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1R,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1R,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1S,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1S,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1S,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1S,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1R,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1R,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— 2-[(1R)-1-(1-cyclohexyltetrazol-5-yl)sulfanylethyl]-5-methyl-1,3,4-thiadiazole —— C12H18N6S2
    2-[(1R)-1-(1-cyclohexyltetrazol-5-yl)sulfanylethyl]-5-methyl-1,3,4-thiadiazole
    —— 2-[(1S)-1-(1-cyclohexyltetrazol-5-yl)sulfanylethyl]-5-methyl-1,3,4-thiadiazole —— C12H18N6S2
    2-[(1S)-1-(1-cyclohexyltetrazol-5-yl)sulfanylethyl]-5-methyl-1,3,4-thiadiazole
    —— (2S)-N-methyl-2-(5-nitropyridin-2-yl)sulfanyl-3-phenylpropanamide —— C15H15N3O3S
    (2S)-N-methyl-2-(5-nitropyridin-2-yl)sulfanyl-3-phenylpropanamide
    —— (2R)-N-methyl-2-(5-nitropyridin-2-yl)sulfanyl-3-phenylpropanamide —— C15H15N3O3S
    (2R)-N-methyl-2-(5-nitropyridin-2-yl)sulfanyl-3-phenylpropanamide
    —— (2R)-2-[(4-ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-3-phenylpropanamide —— C15H20N4OS
    (2R)-2-[(4-ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-3-phenylpropanamide
    —— (2S)-2-[(4-ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-3-phenylpropanamide —— C15H20N4OS
    (2S)-2-[(4-ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-methyl-3-phenylpropanamide
    —— (1R)-1-(3,4-difluorophenyl)-2-[[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanol —— C12H13F2N3OS2
    (1R)-1-(3,4-difluorophenyl)-2-[[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanol
    —— (1S)-1-(3,4-difluorophenyl)-2-[[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanol —— C12H13F2N3OS2
    (1S)-1-(3,4-difluorophenyl)-2-[[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanol
    —— (2S)-N-(2-methoxyethyl)-N-(2-methylpropyl)-2-methylsulfonylpropanamide —— C11H23NO4S
    (2S)-N-(2-methoxyethyl)-N-(2-methylpropyl)-2-methylsulfonylpropanamide
    —— (2R)-N-(2-methoxyethyl)-N-(2-methylpropyl)-2-methylsulfonylpropanamide —— C11H23NO4S
    (2R)-N-(2-methoxyethyl)-N-(2-methylpropyl)-2-methylsulfonylpropanamide
    —— N-[(2R)-butan-2-yl]-N-methyl-2-(2-methylpropylsulfonyl)acetamide —— C11H23NO3S
    N-[(2R)-butan-2-yl]-N-methyl-2-(2-methylpropylsulfonyl)acetamide
    —— 1-[2-[[5-[(5R)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]pyrrolidin-2-one —— C20H27N3O2S2
    1-[2-[[5-[(5R)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]pyrrolidin-2-one
    —— 1-[[(2S)-oxolan-2-yl]methyl]-5-pentylsulfanyltetrazole —— C11H20N4OS
    1-[[(2S)-oxolan-2-yl]methyl]-5-pentylsulfanyltetrazole
    —— 2-pentylsulfanyl-5-[(2S)-2-phenylpropyl]-1,3,4-oxadiazole —— C16H22N2OS
    2-pentylsulfanyl-5-[(2S)-2-phenylpropyl]-1,3,4-oxadiazole
    —— 2-pentylsulfanyl-5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazole —— C16H22N2OS
    2-pentylsulfanyl-5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazole
    —— 1-[2-[[5-[(5S)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]pyrrolidin-2-one —— C20H27N3O2S2
    1-[2-[[5-[(5S)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]pyrrolidin-2-one
    —— (2R)-2-methylsulfonyl-N,N-dipropylpropanamide —— C10H21NO3S
    (2R)-2-methylsulfonyl-N,N-dipropylpropanamide
    —— (2S)-2-methylsulfonyl-N,N-dipropylpropanamide —— C10H21NO3S
    (2S)-2-methylsulfonyl-N,N-dipropylpropanamide
    —— 2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1S,2S)-2-methylcyclohexyl]acetamide —— C13H25NO4S
    2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1S,2S)-2-methylcyclohexyl]acetamide
    —— 2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1S,2R)-2-methylcyclohexyl]acetamide —— C13H25NO4S
    2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1S,2R)-2-methylcyclohexyl]acetamide
    —— 2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1R,2R)-2-methylcyclohexyl]acetamide —— C13H25NO4S
    2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1R,2R)-2-methylcyclohexyl]acetamide
    —— 2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1R,2S)-2-methylcyclohexyl]acetamide —— C13H25NO4S
    2-(2-methoxyethylsulfonyl)-N-methyl-N-[(1R,2S)-2-methylcyclohexyl]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide —— C14H13ClN2OS2
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]acetamide —— C18H19ClN2OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-pyridin-4-ylmethylideneamino]acetamide —— C14H12ClN3OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-pyridin-4-ylmethylideneamino]acetamide