摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— dimethyl (3S,4S,6S)-5,5-dicyano-4-(4-fluorophenyl)-2-hydroxy-6-(4-methylsulfanylphenyl)cyclohexene-1,3-dicarboxylate —— C25H21FN2O5S
    dimethyl (3S,4S,6S)-5,5-dicyano-4-(4-fluorophenyl)-2-hydroxy-6-(4-methylsulfanylphenyl)cyclohexene-1,3-dicarboxylate
    —— dimethyl (3S,4R,6S)-5,5-dicyano-2-hydroxy-6-(4-methylsulfanylphenyl)-4-pyridin-4-ylcyclohexene-1,3-dicarboxylate —— C24H21N3O5S
    dimethyl (3S,4R,6S)-5,5-dicyano-2-hydroxy-6-(4-methylsulfanylphenyl)-4-pyridin-4-ylcyclohexene-1,3-dicarboxylate
    —— (8R,8aS)-6-amino-8-(4-methylsulfanylphenyl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile —— C22H23N5S
    (8R,8aS)-6-amino-8-(4-methylsulfanylphenyl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile
    —— (3S,4R)-1-benzyl-3,4-bis[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione —— C23H17Cl2NO2S2
    (3S,4R)-1-benzyl-3,4-bis[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione
    —— (3R)-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyloxolane-2,5-dione —— C10H5ClF3NO3S
    (3R)-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyloxolane-2,5-dione
    —— (3S)-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyloxolane-2,5-dione —— C10H5ClF3NO3S
    (3S)-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyloxolane-2,5-dione
    —— (2Z,5R)-2-[(Z)-[(1R)-cyclohex-3-en-1-yl]methylidenehydrazinylidene]-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazolidin-4-one —— C18H19F2N3OS2
    (2Z,5R)-2-[(Z)-[(1R)-cyclohex-3-en-1-yl]methylidenehydrazinylidene]-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazolidin-4-one
    —— 2-[(2,5-dimethylphenyl)methylsulfanyl]-5-[(2S)-pyrrolidin-1-ium-2-yl]-1,3,4-oxadiazole —— C15H20N3OS+
    2-[(2,5-dimethylphenyl)methylsulfanyl]-5-[(2S)-pyrrolidin-1-ium-2-yl]-1,3,4-oxadiazole
    —— cyclohexyl 2-[[5-[(2,4-dimethylanilino)methyl]-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]acetate —— C24H34N4O3S
    cyclohexyl 2-[[5-[(2,4-dimethylanilino)methyl]-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]acetate
    —— 2-(3-Chlorobenzylthio)-5-(4-pyridyl)-1,3,4-oxadiazole —— C14H10ClN3OS
    2-(3-Chlorobenzylthio)-5-(4-pyridyl)-1,3,4-oxadiazole
    —— (1S,5S,6R)-2-amino-4,4-dimethoxy-6-(4-methylsulfanylphenyl)-3-azabicyclo[3.1.0]hex-2-ene-1,5-dicarbonitrile —— C16H16N4O2S
    (1S,5S,6R)-2-amino-4,4-dimethoxy-6-(4-methylsulfanylphenyl)-3-azabicyclo[3.1.0]hex-2-ene-1,5-dicarbonitrile
    —— (1S,5S,6S)-2-amino-4,4-dimethoxy-6-(4-methylsulfanylphenyl)-3-azabicyclo[3.1.0]hex-2-ene-1,5-dicarbonitrile —— C16H16N4O2S
    (1S,5S,6S)-2-amino-4,4-dimethoxy-6-(4-methylsulfanylphenyl)-3-azabicyclo[3.1.0]hex-2-ene-1,5-dicarbonitrile
    —— N-(2-Methoxy-ethyl)-4-[4-(6-phenylsulfanyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-ylamino]-benzenesulfonamide —— C26H24N6O3S2
    N-(2-Methoxy-ethyl)-4-[4-(6-phenylsulfanyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-ylamino]-benzenesulfonamide
    —— (4E)-4-{4-[(4-chlorophenyl)sulfanyl]benzylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one —— C23H17ClN2OS
    (4E)-4-{4-[(4-chlorophenyl)sulfanyl]benzylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
    —— ethyl (1S,5S,6R)-5-hydroxy-4,4-dimethyl-1-(trifluoromethyl)-2-oxa-7-thiabicyclo[3.2.1]octane-6-carboxylate —— C12H17F3O4S
    ethyl (1S,5S,6R)-5-hydroxy-4,4-dimethyl-1-(trifluoromethyl)-2-oxa-7-thiabicyclo[3.2.1]octane-6-carboxylate
    —— [(E)-4-amino-3-cyano-2-oxopent-3-enyl] 3-(2-chlorophenyl)sulfanylpropanoate —— C15H15ClN2O3S
    [(E)-4-amino-3-cyano-2-oxopent-3-enyl] 3-(2-chlorophenyl)sulfanylpropanoate
    —— ethyl (1S,5S,6S)-5-hydroxy-4,4-dimethyl-1-(trifluoromethyl)-2-oxa-7-thiabicyclo[3.2.1]octane-6-carboxylate —— C12H17F3O4S
    ethyl (1S,5S,6S)-5-hydroxy-4,4-dimethyl-1-(trifluoromethyl)-2-oxa-7-thiabicyclo[3.2.1]octane-6-carboxylate
    —— (14Z)-14-[[5-(1,3-benzothiazol-2-ylsulfanyl)furan-2-yl]methylidene]-11-phenyl-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-13-one —— C32H21N3O2S3
    (14Z)-14-[[5-(1,3-benzothiazol-2-ylsulfanyl)furan-2-yl]methylidene]-11-phenyl-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-13-one
    —— (10Z)-10-({5-[(4-chlorophenyl)sulfanyl]furan-2-yl}methylidene)-7-(2-methoxyphenyl)-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one —— C32H23ClN2O3S2
    (10Z)-10-({5-[(4-chlorophenyl)sulfanyl]furan-2-yl}methylidene)-7-(2-methoxyphenyl)-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one
    —— (2S)-2-hydroxy-2-(2-methylsulfanylpyrimidin-4-yl)acetonitrile —— C7H7N3OS
    (2S)-2-hydroxy-2-(2-methylsulfanylpyrimidin-4-yl)acetonitrile
    —— (2R)-2-hydroxy-2-(2-methylsulfanylpyrimidin-4-yl)acetonitrile —— C7H7N3OS
    (2R)-2-hydroxy-2-(2-methylsulfanylpyrimidin-4-yl)acetonitrile
    —— [(2R)-1-(tert-butylamino)-1-oxopropan-2-yl] (1'S,5'S)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate —— C19H31NO3S2
    [(2R)-1-(tert-butylamino)-1-oxopropan-2-yl] (1'S,5'S)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate
    —— (5R,7R)-3-(3-nitro-1,2,4-triazol-1-yl)-N-(2-phenylsulfanylphenyl)adamantane-1-carboxamide —— C25H25N5O3S
    (5R,7R)-3-(3-nitro-1,2,4-triazol-1-yl)-N-(2-phenylsulfanylphenyl)adamantane-1-carboxamide
    —— (5S,7S)-3-(3-nitro-1,2,4-triazol-1-yl)-N-(2-phenylsulfanylphenyl)adamantane-1-carboxamide —— C25H25N5O3S
    (5S,7S)-3-(3-nitro-1,2,4-triazol-1-yl)-N-(2-phenylsulfanylphenyl)adamantane-1-carboxamide
    —— [(2S)-1-(tert-butylamino)-1-oxopropan-2-yl] (1'S,5'S)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate —— C19H31NO3S2
    [(2S)-1-(tert-butylamino)-1-oxopropan-2-yl] (1'S,5'S)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate
    —— (6Z)-2-butyl-6-[[5-(4-chlorophenyl)sulfanylfuran-2-yl]methylidene]-5-imino-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one —— C20H17ClN4O2S2
    (6Z)-2-butyl-6-[[5-(4-chlorophenyl)sulfanylfuran-2-yl]methylidene]-5-imino-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one
    —— (1R,4S)-4,7,7-trimethyl-2,3-dioxo-N-(2-phenylsulfanylphenyl)bicyclo[2.2.1]heptane-1-carboxamide —— C23H23NO3S
    (1R,4S)-4,7,7-trimethyl-2,3-dioxo-N-(2-phenylsulfanylphenyl)bicyclo[2.2.1]heptane-1-carboxamide
    —— 3-(2-Chlorobenzyl)-5-({5-[(4-chlorophenyl)sulfanyl]thien-2-yl}methylene)-1,3-thiazolidine-2,4-dione —— C21H13Cl2NO2S3
    3-(2-Chlorobenzyl)-5-({5-[(4-chlorophenyl)sulfanyl]thien-2-yl}methylene)-1,3-thiazolidine-2,4-dione
    —— (1'R,5'R)-N-(furan-2-ylmethyl)spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxamide —— C17H23NO2S2
    (1'R,5'R)-N-(furan-2-ylmethyl)spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxamide
    —— (1'S,5'S)-N-(furan-2-ylmethyl)spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxamide —— C17H23NO2S2
    (1'S,5'S)-N-(furan-2-ylmethyl)spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxamide
    —— prop-2-enyl (2E,5S)-2-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H23ClN2O4S2
    prop-2-enyl (2E,5S)-2-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— (5Z)-3-(2-chloro-6-fluorobenzyl)-5-({5-[(4-chlorophenyl)sulfanyl]thiophen-2-yl}methylidene)-1,3-thiazolidine-2,4-dione —— C21H12Cl2FNO2S3
    (5Z)-3-(2-chloro-6-fluorobenzyl)-5-({5-[(4-chlorophenyl)sulfanyl]thiophen-2-yl}methylidene)-1,3-thiazolidine-2,4-dione
    —— methyl (2E,5R)-2-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H21ClN2O4S2
    methyl (2E,5R)-2-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— methyl (2E,5S)-2-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H21ClN2O4S2
    methyl (2E,5S)-2-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— 1-[(3R)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C22H26N4O4S5
    1-[(3R)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 2-[(5-benzylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(Z)-[(E)-2-chloro-3-phenylprop-2-enylidene]amino]acetamide —— C20H17ClN4OS3
    2-[(5-benzylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(Z)-[(E)-2-chloro-3-phenylprop-2-enylidene]amino]acetamide
    —— 1-[(3R)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C22H26N4O4S5
    1-[(3R)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 1-[(3S)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C24H30N4O4S5
    1-[(3S)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 1-[(3R)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C24H30N4O4S5
    1-[(3R)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 1-[(3S)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C22H26N4O4S5
    1-[(3S)-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3S)-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 1-[(3S)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea —— C24H30N4O4S5
    1-[(3S)-3-methyl-1,1-dioxothiolan-3-yl]-3-[4-[4-[[(3R)-3-methyl-1,1-dioxothiolan-3-yl]carbamothioylamino]phenyl]sulfanylphenyl]thiourea
    —— 2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-[(Z)-3-(furan-2-yl)prop-2-enylidene]amino]acetamide —— C18H15ClN4O2S3
    2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-[(Z)-3-(furan-2-yl)prop-2-enylidene]amino]acetamide
    —— 2-[(2-bromophenyl)methylsulfanyl]-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione —— C12H8BrN3O2S2
    2-[(2-bromophenyl)methylsulfanyl]-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione
    —— N-cyclohexyl-2-[(4-methoxy-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]propanamide —— C14H21N3O3S
    N-cyclohexyl-2-[(4-methoxy-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]propanamide
    —— 2-[[5,6-Bis(furan-3-yl)-1,2,4-triazin-3-yl]sulfanyl]-1-(5-chlorothiophen-2-yl)ethanone —— C17H10ClN3O3S2
    2-[[5,6-Bis(furan-3-yl)-1,2,4-triazin-3-yl]sulfanyl]-1-(5-chlorothiophen-2-yl)ethanone
    —— 2-{[3-cyano-4-(methoxymethyl)-6-methylpyridin-2-yl]sulfanyl}-N-(1-methoxypropan-2-yl)acetamide —— C15H21N3O3S
    2-{[3-cyano-4-(methoxymethyl)-6-methylpyridin-2-yl]sulfanyl}-N-(1-methoxypropan-2-yl)acetamide
    —— 2-[(4-methylphenyl)methylsulfanyl]-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione —— C13H11N3O2S2
    2-[(4-methylphenyl)methylsulfanyl]-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione
    —— 7-amino-2-ethyl-9H-[1,2,4]triazolo[5,1-b][1,3]benzothiazin-9-ol —— C11H12N4OS
    7-amino-2-ethyl-9H-[1,2,4]triazolo[5,1-b][1,3]benzothiazin-9-ol
    —— 3-[(5-Amino-1,2,4-thiadiazol-3-yl)sulfanyl]propanenitrile —— C5H6N4S2
    3-[(5-Amino-1,2,4-thiadiazol-3-yl)sulfanyl]propanenitrile
    —— 2-{[5-(4-amino-1,2,5-oxadiazol-3-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-cyclopentylacetamide —— C13H19N7O2S
    2-{[5-(4-amino-1,2,5-oxadiazol-3-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-cyclopentylacetamide