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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(2-fluorophenyl)methylideneamino]acetamide —— C15H12ClFN2OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(2-fluorophenyl)methylideneamino]acetamide
    —— (2S)-N,N-bis(3-methylbutyl)-2-methylsulfonylpropanamide —— C14H29NO3S
    (2S)-N,N-bis(3-methylbutyl)-2-methylsulfonylpropanamide
    —— N-[(2R)-butan-2-yl]-N-butyl-2-(2-methylpropylsulfonyl)acetamide —— C14H29NO3S
    N-[(2R)-butan-2-yl]-N-butyl-2-(2-methylpropylsulfonyl)acetamide
    —— (2S)-N,N-diethyl-2-(3-methylbutylsulfonyl)propanamide —— C12H25NO3S
    (2S)-N,N-diethyl-2-(3-methylbutylsulfonyl)propanamide
    —— (2S)-N-butyl-2-(3-methylbutylsulfonyl)propanamide —— C12H25NO3S
    (2S)-N-butyl-2-(3-methylbutylsulfonyl)propanamide
    —— (2R)-N,N-diethyl-2-(3-methylbutylsulfonyl)propanamide —— C12H25NO3S
    (2R)-N,N-diethyl-2-(3-methylbutylsulfonyl)propanamide
    —— (2S)-N-(cyclopropylmethyl)-2-methylsulfonyl-N-propylpropanamide —— C11H21NO3S
    (2S)-N-(cyclopropylmethyl)-2-methylsulfonyl-N-propylpropanamide
    —— (2R)-2-methylsulfonyl-N,N-bis(prop-2-enyl)propanamide —— C10H17NO3S
    (2R)-2-methylsulfonyl-N,N-bis(prop-2-enyl)propanamide
    —— (2R)-N-(cyclopropylmethyl)-2-methylsulfonyl-N-propylpropanamide —— C11H21NO3S
    (2R)-N-(cyclopropylmethyl)-2-methylsulfonyl-N-propylpropanamide
    —— (2R)-2-(3-methylbutylsulfonyl)-N,N-di(propan-2-yl)propanamide —— C14H29NO3S
    (2R)-2-(3-methylbutylsulfonyl)-N,N-di(propan-2-yl)propanamide
    —— (2R)-N-butyl-2-(3-methylbutylsulfonyl)propanamide —— C12H25NO3S
    (2R)-N-butyl-2-(3-methylbutylsulfonyl)propanamide
    —— (2S)-2-methylsulfonyl-N,N-bis(prop-2-enyl)propanamide —— C10H17NO3S
    (2S)-2-methylsulfonyl-N,N-bis(prop-2-enyl)propanamide
    —— N-[(2S)-butan-2-yl]-N-butyl-2-(2-methylpropylsulfonyl)acetamide —— C14H29NO3S
    N-[(2S)-butan-2-yl]-N-butyl-2-(2-methylpropylsulfonyl)acetamide
    —— (2S)-2-(3-methylbutylsulfonyl)-N,N-di(propan-2-yl)propanamide —— C14H29NO3S
    (2S)-2-(3-methylbutylsulfonyl)-N,N-di(propan-2-yl)propanamide
    —— (2S)-N-(2-adamantyl)-2-methylsulfonylpropanamide —— C14H23NO3S
    (2S)-N-(2-adamantyl)-2-methylsulfonylpropanamide
    —— (2R)-N-(2-adamantyl)-2-methylsulfonylpropanamide —— C14H23NO3S
    (2R)-N-(2-adamantyl)-2-methylsulfonylpropanamide
    —— 2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone —— C11H16F3N5O2S
    2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-(4-chlorophenyl)ethyl]acetamide —— C13H13ClF3N5OS
    2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-(4-chlorophenyl)ethyl]acetamide
    —— 2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]ethanone —— C11H16F3N5O2S
    2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 3-[(1S)-1-phenylethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine —— C11H11F3N4S
    3-[(1S)-1-phenylethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine
    —— 3-[(1R)-1-phenylethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine —— C11H11F3N4S
    3-[(1R)-1-phenylethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine
    —— 2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]ethanone —— C11H16F3N5O2S
    2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-(4-chlorophenyl)ethyl]acetamide —— C13H13ClF3N5OS
    2-[[4-amino-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-(4-chlorophenyl)ethyl]acetamide
    —— N-methyl-N-[3-(4-methylphenyl)sulfanylpropyl]-2-[(2S)-4-propan-2-ylmorpholin-2-yl]acetamide —— C20H32N2O2S
    N-methyl-N-[3-(4-methylphenyl)sulfanylpropyl]-2-[(2S)-4-propan-2-ylmorpholin-2-yl]acetamide
    —— N-methyl-N-[3-(4-methylphenyl)sulfanylpropyl]-2-[(2R)-4-propan-2-ylmorpholin-2-yl]acetamide —— C20H32N2O2S
    N-methyl-N-[3-(4-methylphenyl)sulfanylpropyl]-2-[(2R)-4-propan-2-ylmorpholin-2-yl]acetamide
    —— 5-methyl-3-[(2R)-1-[[5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl]methyl]piperidin-2-yl]-1,2-oxazole —— C17H21N5O2S
    5-methyl-3-[(2R)-1-[[5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl]methyl]piperidin-2-yl]-1,2-oxazole
    —— 5-methyl-3-[(2S)-1-[[5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl]methyl]piperidin-2-yl]-1,2-oxazole —— C17H21N5O2S
    5-methyl-3-[(2S)-1-[[5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl]methyl]piperidin-2-yl]-1,2-oxazole
    —— (3R)-N-methyl-N-[(3-methylsulfanylphenyl)methyl]oxolane-3-carboxamide —— C14H19NO2S
    (3R)-N-methyl-N-[(3-methylsulfanylphenyl)methyl]oxolane-3-carboxamide
    —— 5-[[(2S)-2-(methoxymethyl)piperidin-1-yl]methyl]-2-methylsulfanylpyrimidine —— C13H21N3OS
    5-[[(2S)-2-(methoxymethyl)piperidin-1-yl]methyl]-2-methylsulfanylpyrimidine
    —— 5-[[(2R)-2-(methoxymethyl)piperidin-1-yl]methyl]-2-methylsulfanylpyrimidine —— C13H21N3OS
    5-[[(2R)-2-(methoxymethyl)piperidin-1-yl]methyl]-2-methylsulfanylpyrimidine
    —— N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-3-methylsulfonylpropanamide —— C12H23NO3S
    N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-3-methylsulfonylpropanamide
    —— N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-3-methylsulfonylpropanamide —— C12H23NO3S
    N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-3-methylsulfonylpropanamide
    —— N-[(2R)-butan-2-yl]-N-butyl-3-methylsulfonylpropanamide —— C12H25NO3S
    N-[(2R)-butan-2-yl]-N-butyl-3-methylsulfonylpropanamide
    —— N-[(2R)-butan-2-yl]-N-methyl-3-methylsulfonylpropanamide —— C9H19NO3S
    N-[(2R)-butan-2-yl]-N-methyl-3-methylsulfonylpropanamide
    —— N-[(2S)-butan-2-yl]-N-butyl-3-methylsulfonylpropanamide —— C12H25NO3S
    N-[(2S)-butan-2-yl]-N-butyl-3-methylsulfonylpropanamide
    —— N-[(2S)-butan-2-yl]-N-methyl-3-methylsulfonylpropanamide —— C9H19NO3S
    N-[(2S)-butan-2-yl]-N-methyl-3-methylsulfonylpropanamide
    —— N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C23H31N3O2S
    N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C19H30N4O2S2
    N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[[(2S)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C19H30N4O2S2
    N-cyclopropyl-N-(4-methylcyclohexyl)-2-[[5-[[(2R)-oxolan-2-yl]methylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-piperidin-1-ylthiophen-2-yl)methanimine —— C19H20ClN5S2
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-piperidin-1-ylthiophen-2-yl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,6-difluorophenyl)methanimine —— C16H11ClF2N4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2,6-difluorophenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3,4-difluorophenyl)methanimine —— C16H11ClF2N4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3,4-difluorophenyl)methanimine
    —— 2-(4-bromophenyl)sulfanyl-N-[(2R)-2-(furan-2-yl)-2-hydroxyethyl]pyridine-3-carboxamide —— C18H15BrN2O3S
    2-(4-bromophenyl)sulfanyl-N-[(2R)-2-(furan-2-yl)-2-hydroxyethyl]pyridine-3-carboxamide
    —— 2-(4-bromophenyl)sulfanyl-N-[(2S)-2-(furan-2-yl)-2-hydroxyethyl]pyridine-3-carboxamide —— C18H15BrN2O3S
    2-(4-bromophenyl)sulfanyl-N-[(2S)-2-(furan-2-yl)-2-hydroxyethyl]pyridine-3-carboxamide
    —— 4-(4-chlorophenyl)sulfanyl-N-[(2R)-2-(4-fluorophenyl)-2-hydroxyethyl]butanamide —— C18H19ClFNO2S
    4-(4-chlorophenyl)sulfanyl-N-[(2R)-2-(4-fluorophenyl)-2-hydroxyethyl]butanamide
    —— 4-(4-chlorophenyl)sulfanyl-N-[(2S)-2-(4-fluorophenyl)-2-hydroxyethyl]butanamide —— C18H19ClFNO2S
    4-(4-chlorophenyl)sulfanyl-N-[(2S)-2-(4-fluorophenyl)-2-hydroxyethyl]butanamide
    —— 2-(2,4-dimethylphenyl)sulfanyl-N-[(2R)-2-(4-fluorophenyl)-2-hydroxyethyl]pyridine-3-carboxamide —— C22H21FN2O2S
    2-(2,4-dimethylphenyl)sulfanyl-N-[(2R)-2-(4-fluorophenyl)-2-hydroxyethyl]pyridine-3-carboxamide
    —— 2-(2,4-dimethylphenyl)sulfanyl-N-[(2S)-2-(4-fluorophenyl)-2-hydroxyethyl]pyridine-3-carboxamide —— C22H21FN2O2S
    2-(2,4-dimethylphenyl)sulfanyl-N-[(2S)-2-(4-fluorophenyl)-2-hydroxyethyl]pyridine-3-carboxamide
    —— (4R)-1-[(2-butylsulfanylpyrimidin-5-yl)methyl]azepan-4-amine —— C15H26N4S
    (4R)-1-[(2-butylsulfanylpyrimidin-5-yl)methyl]azepan-4-amine
    —— (4S)-1-[(2-butylsulfanylpyrimidin-5-yl)methyl]azepan-4-amine —— C15H26N4S
    (4S)-1-[(2-butylsulfanylpyrimidin-5-yl)methyl]azepan-4-amine