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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(Z)-(4-methylphenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C14H14N4OS
    N-[(Z)-(4-methylphenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— 3-[5-(4-ethylsulfanylphenyl)-1,2-oxazol-3-yl]propanoic acid —— C14H15NO3S
    3-[5-(4-ethylsulfanylphenyl)-1,2-oxazol-3-yl]propanoic acid
    —— 5-Methyl-4-(4-propan-2-ylsulfanylphenyl)-1,2-oxazole-3-carboxylic acid —— C14H15NO3S
    5-Methyl-4-(4-propan-2-ylsulfanylphenyl)-1,2-oxazole-3-carboxylic acid
    —— 2-methyl-N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide —— C18H15N3O2S
    2-methyl-N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide
    —— 3-Methyl-5-(4-propan-2-ylsulfanylphenyl)-1,2-oxazole-4-carboxylic acid —— C14H15NO3S
    3-Methyl-5-(4-propan-2-ylsulfanylphenyl)-1,2-oxazole-4-carboxylic acid
    —— 2-[(3,5-dioxo-2H-1,2,4-triazin-6-yl)sulfanyl]-N-[(Z)-(2-fluorophenyl)methylideneamino]acetamide —— C12H10FN5O3S
    2-[(3,5-dioxo-2H-1,2,4-triazin-6-yl)sulfanyl]-N-[(Z)-(2-fluorophenyl)methylideneamino]acetamide
    —— (Z)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine —— C15H13N5S
    (Z)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine
    —— N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C14H12ClN3OS
    N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— 4-(4-Cyclopentylsulfanylphenyl)-1,3-thiazol-5-amine —— C14H16N2S2
    4-(4-Cyclopentylsulfanylphenyl)-1,3-thiazol-5-amine
    —— 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(1E)-1-(4-fluorophenyl)ethylidene]acetohydrazide —— C16H17FN4OS
    2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(1E)-1-(4-fluorophenyl)ethylidene]acetohydrazide
    —— 2-[3-methyl-5-(4-propan-2-ylsulfanylphenyl)-1,2-oxazol-4-yl]ethanamine —— C15H20N2OS
    2-[3-methyl-5-(4-propan-2-ylsulfanylphenyl)-1,2-oxazol-4-yl]ethanamine
    —— (2R)-2-(4-cyclopentylsulfanylphenyl)-2-cyclopropylacetic acid —— C16H20O2S
    (2R)-2-(4-cyclopentylsulfanylphenyl)-2-cyclopropylacetic acid
    —— 6-(4-cyclopentylsulfanylphenyl)hexan-2-one —— C17H24OS
    6-(4-cyclopentylsulfanylphenyl)hexan-2-one
    —— (2S)-2-(4-cyclopentylsulfanylphenyl)-2-cyclopropylacetic acid —— C16H20O2S
    (2S)-2-(4-cyclopentylsulfanylphenyl)-2-cyclopropylacetic acid
    —— 2-(4-Ethylsulfanylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-6-amine —— C12H12N4S2
    2-(4-Ethylsulfanylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-6-amine
    —— [2-(4-Methylsulfanylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]methanamine —— C12H12N4S2
    [2-(4-Methylsulfanylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]methanamine
    —— (E)-2-(4-chlorophenylthio)-N'-(pyridin-3-ylmethylene)acetohydrazide 329699-47-0 C14H12ClN3OS
    (E)-2-(4-chlorophenylthio)-N'-(pyridin-3-ylmethylene)acetohydrazide
    —— [3-(4-Methylsulfanylphenyl)imidazo[5,1-b][1,3]thiazol-5-yl]methanamine —— C13H13N3S2
    [3-(4-Methylsulfanylphenyl)imidazo[5,1-b][1,3]thiazol-5-yl]methanamine
    —— [5-(4-Cyclopentylsulfanylphenyl)-1,3,4-oxadiazol-2-yl]methanamine —— C14H17N3OS
    [5-(4-Cyclopentylsulfanylphenyl)-1,3,4-oxadiazol-2-yl]methanamine
    —— 3-(4-Ethylsulfanylphenyl)imidazo[5,1-b][1,3]thiazol-5-amine —— C13H13N3S2
    3-(4-Ethylsulfanylphenyl)imidazo[5,1-b][1,3]thiazol-5-amine
    —— (E)-4-(4-chlorophenyl)sulfanylbut-3-en-2-one —— C10H9ClOS
    (E)-4-(4-chlorophenyl)sulfanylbut-3-en-2-one
    —— (E)-[(3E)-3-hydrazinylidene-1,4-bis(methylsulfinyl)butan-2-ylidene]hydrazine —— C6H14N4O2S2
    (E)-[(3E)-3-hydrazinylidene-1,4-bis(methylsulfinyl)butan-2-ylidene]hydrazine
    —— 2-[4-Methyl-6-(4-methylsulfanylphenyl)-1,3,5-triazin-2-yl]acetic acid —— C13H13N3O2S
    2-[4-Methyl-6-(4-methylsulfanylphenyl)-1,3,5-triazin-2-yl]acetic acid
    —— 5-(4-Cyclopentylsulfanylphenyl)-1,2,4-triazin-3-amine —— C14H16N4S
    5-(4-Cyclopentylsulfanylphenyl)-1,2,4-triazin-3-amine
    —— N-[(Z)-[2-(dimethylamino)-6,7-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-4-ylidene]amino]acetamide —— C9H14N6OS
    N-[(Z)-[2-(dimethylamino)-6,7-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-4-ylidene]amino]acetamide
    —— N-[(Z)-(4-fluorophenyl)methylideneamino]-2-(2-methylphenyl)sulfanylacetamide —— C16H15FN2OS
    N-[(Z)-(4-fluorophenyl)methylideneamino]-2-(2-methylphenyl)sulfanylacetamide
    —— 2-methyl-6-(4-propan-2-ylsulfanylphenyl)hexan-2-ol —— C16H26OS
    2-methyl-6-(4-propan-2-ylsulfanylphenyl)hexan-2-ol
    —— 2,2-Dimethyl-4-(4-propan-2-ylsulfanylphenyl)butanoic acid —— C15H22O2S
    2,2-Dimethyl-4-(4-propan-2-ylsulfanylphenyl)butanoic acid
    —— (1R)-1-(4-cyclopentylsulfanylphenyl)butane-1,4-diol —— C15H22O2S
    (1R)-1-(4-cyclopentylsulfanylphenyl)butane-1,4-diol
    —— (3S)-3-(4-methylsulfanylphenyl)-3-piperidin-4-ylpropan-1-ol —— C15H23NOS
    (3S)-3-(4-methylsulfanylphenyl)-3-piperidin-4-ylpropan-1-ol
    —— 2-methyl-6-(4-propan-2-ylsulfanylphenyl)hexan-2-amine —— C16H27NS
    2-methyl-6-(4-propan-2-ylsulfanylphenyl)hexan-2-amine
    —— 5-(4-cyclopentylsulfanylphenyl)pentan-1-ol —— C16H24OS
    5-(4-cyclopentylsulfanylphenyl)pentan-1-ol
    —— 1-(4-Cyclopentylsulfanylphenyl)pentan-3-one —— C16H22OS
    1-(4-Cyclopentylsulfanylphenyl)pentan-3-one
    —— (3S)-1-(4-cyclopentylsulfanylphenyl)pentan-3-amine —— C16H25NS
    (3S)-1-(4-cyclopentylsulfanylphenyl)pentan-3-amine
    —— (3R)-1-(4-cyclopentylsulfanylphenyl)pentan-3-amine —— C16H25NS
    (3R)-1-(4-cyclopentylsulfanylphenyl)pentan-3-amine
    —— 5-(4-cyclopentylsulfanylphenyl)pentanal —— C16H22OS
    5-(4-cyclopentylsulfanylphenyl)pentanal
    —— (Phenylthio)acetic acid, 3-chloroprop-2-enyl ester —— C11H11ClO2S
    (Phenylthio)acetic acid, 3-chloroprop-2-enyl ester
    —— Methylpropenyl tetrasulfide —— C4H8S4
    Methylpropenyl tetrasulfide
    —— 2-[(5-propyl-1,2,4-oxadiazol-3-yl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole —— C13H13N5O2S
    2-[(5-propyl-1,2,4-oxadiazol-3-yl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole
    —— 6-(4-ethylsulfanylphenyl)-2-methylhexan-2-ol —— C15H24OS
    6-(4-ethylsulfanylphenyl)-2-methylhexan-2-ol
    —— (1R)-1-(4-propan-2-ylsulfanylphenyl)pentane-1,5-diol —— C14H22O2S
    (1R)-1-(4-propan-2-ylsulfanylphenyl)pentane-1,5-diol
    —— (1S)-1-(4-propan-2-ylsulfanylphenyl)pentane-1,5-diol —— C14H22O2S
    (1S)-1-(4-propan-2-ylsulfanylphenyl)pentane-1,5-diol
    —— 2-cyclopropyl-5-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3,4-oxadiazole —— C17H18N4O2S
    2-cyclopropyl-5-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3,4-oxadiazole
    —— 4-(4-Ethylsulfanylphenyl)-2,2-dimethylbutanoic acid —— C14H20O2S
    4-(4-Ethylsulfanylphenyl)-2,2-dimethylbutanoic acid
    —— ethyl (2Z)-2-(4-chlorobenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C24H21ClN2O3S2
    ethyl (2Z)-2-(4-chlorobenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— 6-(4-ethylsulfanylphenyl)-2-methylhexan-2-amine —— C15H25NS
    6-(4-ethylsulfanylphenyl)-2-methylhexan-2-amine
    —— N-[(E)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide —— C16H17ClN4OS
    N-[(E)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide
    —— 6-(4-propan-2-ylsulfanylphenyl)hexan-2-one —— C15H22OS
    6-(4-propan-2-ylsulfanylphenyl)hexan-2-one
    —— N'-[(E)-(4-bromophenyl)methylidene]-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]propanehydrazide —— C16H17BrN4OS
    N'-[(E)-(4-bromophenyl)methylidene]-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]propanehydrazide
    —— N'-[(E)-(4-fluorophenyl)methylidene]-2-(pyrimidin-2-ylsulfanyl)acetohydrazide —— C13H11FN4OS
    N'-[(E)-(4-fluorophenyl)methylidene]-2-(pyrimidin-2-ylsulfanyl)acetohydrazide