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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine —— C13H19N5S
    (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine
    —— (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine
    —— (1R)-1-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-5-fluorophenyl]-N-methylethanamine —— C13H17FN4S
    (1R)-1-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-5-fluorophenyl]-N-methylethanamine
    —— (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine —— C13H19N5S
    (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine
    —— (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine —— C13H19N5S
    (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-2-ylbutan-2-amine
    —— (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine
    —— (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-methylthiophen-2-yl)propan-2-amine
    —— (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine —— C13H20N4S2
    (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine
    —— (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine —— C13H20N4S2
    (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine
    —— (1S)-1-(3-bromo-4-phenylsulfanylphenyl)-N-methylethanamine —— C15H16BrNS
    (1S)-1-(3-bromo-4-phenylsulfanylphenyl)-N-methylethanamine
    —— (1S)-1-[2-(cyclopentylmethylsulfanyl)-6-fluorophenyl]-N-ethylethanamine —— C16H24FNS
    (1S)-1-[2-(cyclopentylmethylsulfanyl)-6-fluorophenyl]-N-ethylethanamine
    —— (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine —— C13H20N4S2
    (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)butan-2-amine
    —— (2R)-2-(2-chlorophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C12H15ClN4S
    (2R)-2-(2-chlorophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— (1S)-1-[3-bromo-4-(4-methylphenyl)sulfanylphenyl]-N-methylethanamine —— C16H18BrNS
    (1S)-1-[3-bromo-4-(4-methylphenyl)sulfanylphenyl]-N-methylethanamine
    —— (1R)-1-(3-bromo-4-phenylsulfanylphenyl)-N-methylethanamine —— C15H16BrNS
    (1R)-1-(3-bromo-4-phenylsulfanylphenyl)-N-methylethanamine
    —— (1R)-1-[3-bromo-4-[(2R)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine —— C14H22BrNS
    (1R)-1-[3-bromo-4-[(2R)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine
    —— (1S)-1-[3-chloro-4-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]-N-methylethanamine —— C13H17ClN4S
    (1S)-1-[3-chloro-4-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]-N-methylethanamine
    —— (1R)-1-[3-bromo-4-[(2S)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine —— C14H22BrNS
    (1R)-1-[3-bromo-4-[(2S)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine
    —— (1S)-1-[4-(3-bromophenyl)sulfanyl-3-fluorophenyl]-N-methylethanamine —— C15H15BrFNS
    (1S)-1-[4-(3-bromophenyl)sulfanyl-3-fluorophenyl]-N-methylethanamine
    —— N-[(1R)-1-[2-(cyclopentylmethylsulfanyl)phenyl]ethyl]propan-1-amine —— C17H27NS
    N-[(1R)-1-[2-(cyclopentylmethylsulfanyl)phenyl]ethyl]propan-1-amine
    —— (1S)-1-[3-bromo-4-[(2R)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine —— C14H22BrNS
    (1S)-1-[3-bromo-4-[(2R)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine
    —— (1S)-1-[3-bromo-4-[(2S)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine —— C14H22BrNS
    (1S)-1-[3-bromo-4-[(2S)-butan-2-yl]sulfanylphenyl]-N-ethylethanamine
    —— (1S,2R)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine —— C14H15BrClNS2
    (1S,2R)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine
    —— N-[(1S)-1-(3-bromo-4-tert-butylsulfanylphenyl)ethyl]propan-1-amine —— C15H24BrNS
    N-[(1S)-1-(3-bromo-4-tert-butylsulfanylphenyl)ethyl]propan-1-amine
    —— N-[(1R)-1-(3-bromo-4-cyclopentylsulfanylphenyl)ethyl]propan-1-amine —— C16H24BrNS
    N-[(1R)-1-(3-bromo-4-cyclopentylsulfanylphenyl)ethyl]propan-1-amine
    —— N-[(1S)-1-[2-(cyclopentylmethylsulfanyl)phenyl]ethyl]propan-1-amine —— C17H27NS
    N-[(1S)-1-[2-(cyclopentylmethylsulfanyl)phenyl]ethyl]propan-1-amine
    —— (3S,4R)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C14H22BrNS
    (3S,4R)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (1R,2R)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine —— C14H15BrClNS2
    (1R,2R)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine
    —— (3R,4S)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C14H22BrNS
    (3R,4S)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— N-[(1S)-1-(3-bromo-4-cyclopentylsulfanylphenyl)ethyl]propan-1-amine —— C16H24BrNS
    N-[(1S)-1-(3-bromo-4-cyclopentylsulfanylphenyl)ethyl]propan-1-amine
    —— [(2S)-1-[(4-fluorophenyl)methylamino]-1-oxopropan-2-yl] (2R)-2-phenylsulfanylpropanoate —— C19H20FNO3S
    [(2S)-1-[(4-fluorophenyl)methylamino]-1-oxopropan-2-yl] (2R)-2-phenylsulfanylpropanoate
    —— N-[(1R)-1-(3-bromo-4-tert-butylsulfanylphenyl)ethyl]propan-1-amine —— C15H24BrNS
    N-[(1R)-1-(3-bromo-4-tert-butylsulfanylphenyl)ethyl]propan-1-amine
    —— (1R,2S)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine —— C14H15BrClNS2
    (1R,2S)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine
    —— (3R,4R)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C14H22BrNS
    (3R,4R)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (1R)-1-[3-bromo-4-(cyclopentylmethylsulfanyl)phenyl]-N-ethylethanamine —— C16H24BrNS
    (1R)-1-[3-bromo-4-(cyclopentylmethylsulfanyl)phenyl]-N-ethylethanamine
    —— (1S,2S)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine —— C14H15BrClNS2
    (1S,2S)-1-(3-bromophenyl)sulfanyl-1-(5-chlorothiophen-2-yl)butan-2-amine
    —— (3S,4S)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C14H22BrNS
    (3S,4S)-4-(3-bromophenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (1S)-1-[3-bromo-4-(cyclopentylmethylsulfanyl)phenyl]-N-ethylethanamine —— C16H24BrNS
    (1S)-1-[3-bromo-4-(cyclopentylmethylsulfanyl)phenyl]-N-ethylethanamine
    —— (1R)-1-[2-(3-bromophenyl)sulfanyl-6-fluorophenyl]-N-methylethanamine —— C15H15BrFNS
    (1R)-1-[2-(3-bromophenyl)sulfanyl-6-fluorophenyl]-N-methylethanamine
    —— (1R)-1-[4-(3-bromophenyl)sulfanyl-3-fluorophenyl]-N-methylethanamine —— C15H15BrFNS
    (1R)-1-[4-(3-bromophenyl)sulfanyl-3-fluorophenyl]-N-methylethanamine
    —— (1S)-1-[2-(3-bromophenyl)sulfanyl-6-fluorophenyl]-N-methylethanamine —— C15H15BrFNS
    (1S)-1-[2-(3-bromophenyl)sulfanyl-6-fluorophenyl]-N-methylethanamine
    —— (1R)-1-[3-chloro-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanamine —— C15H22ClNS
    (1R)-1-[3-chloro-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanamine
    —— (1R)-N-ethyl-1-[4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine —— C17H27NS
    (1R)-N-ethyl-1-[4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine
    —— (1R)-1-[3-chloro-4-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanamine —— C15H22ClNS
    (1R)-1-[3-chloro-4-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanamine
    —— (1R)-N-ethyl-1-[4-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine —— C17H27NS
    (1R)-N-ethyl-1-[4-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine
    —— (1R)-1-[4-(3-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine —— C15H15BrClNS
    (1R)-1-[4-(3-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine
    —— (1R)-1-[3-bromo-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]-N-methylethanamine —— C16H24BrNS
    (1R)-1-[3-bromo-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]-N-methylethanamine
    —— (1R)-1-[3-chloro-4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine —— C15H22ClNS
    (1R)-1-[3-chloro-4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanamine
    —— (1S)-1-[4-(3-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine —— C15H15BrClNS
    (1S)-1-[4-(3-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine
    —— (1S,2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]cyclohexane-1-carboxylic acid —— C11H17N3O2S
    (1S,2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]cyclohexane-1-carboxylic acid