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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (1R)-N-(2-pyrimidin-4-ylsulfanylethyl)-1-thiophen-2-ylethanamine —— C12H15N3S2
    (1R)-N-(2-pyrimidin-4-ylsulfanylethyl)-1-thiophen-2-ylethanamine
    —— (1S,2R,4S)-4-ethyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid —— C13H18N2O2S
    (1S,2R,4S)-4-ethyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid
    —— (1S,2R,4S)-4-methyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid —— C12H16N2O2S
    (1S,2R,4S)-4-methyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid
    —— (1R,2R,4R)-4-methyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid —— C12H16N2O2S
    (1R,2R,4R)-4-methyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carboxylic acid
    —— [(2S)-1-oxo-1-(2-oxoimidazolidin-1-yl)propan-2-yl] (2S)-2-(4-methylphenyl)sulfanylpropanoate —— C16H20N2O4S
    [(2S)-1-oxo-1-(2-oxoimidazolidin-1-yl)propan-2-yl] (2S)-2-(4-methylphenyl)sulfanylpropanoate
    —— (1S)-N-(2-pyrimidin-4-ylsulfanylethyl)-1-thiophen-2-ylethanamine —— C12H15N3S2
    (1S)-N-(2-pyrimidin-4-ylsulfanylethyl)-1-thiophen-2-ylethanamine
    —— (2S)-N-(2-pyrimidin-4-ylsulfanylethyl)heptan-2-amine —— C13H23N3S
    (2S)-N-(2-pyrimidin-4-ylsulfanylethyl)heptan-2-amine
    —— N'-[(1S)-2-amino-1-(4-methylsulfanylphenyl)ethyl]-N,N,N'-trimethylpropane-1,3-diamine —— C15H27N3S
    N'-[(1S)-2-amino-1-(4-methylsulfanylphenyl)ethyl]-N,N,N'-trimethylpropane-1,3-diamine
    —— N'-[(1R)-2-amino-1-(4-methylsulfanylphenyl)ethyl]-N,N,N'-trimethylpropane-1,3-diamine —— C15H27N3S
    N'-[(1R)-2-amino-1-(4-methylsulfanylphenyl)ethyl]-N,N,N'-trimethylpropane-1,3-diamine
    —— 5-chloro-N'-hydroxy-2-pyrimidin-4-ylsulfanylbenzenecarboximidamide —— C11H9ClN4OS
    5-chloro-N'-hydroxy-2-pyrimidin-4-ylsulfanylbenzenecarboximidamide
    —— N'-hydroxy-3-(pyrimidin-4-ylsulfanylmethyl)benzenecarboximidamide —— C12H12N4OS
    N'-hydroxy-3-(pyrimidin-4-ylsulfanylmethyl)benzenecarboximidamide
    —— 5-fluoro-N'-hydroxy-2-(pyrimidin-4-ylsulfanylmethyl)benzenecarboximidamide —— C12H11FN4OS
    5-fluoro-N'-hydroxy-2-(pyrimidin-4-ylsulfanylmethyl)benzenecarboximidamide
    —— (2R)-N-(2-pyrimidin-4-ylsulfanylethyl)heptan-2-amine —— C13H23N3S
    (2R)-N-(2-pyrimidin-4-ylsulfanylethyl)heptan-2-amine
    —— (2S)-2-[[4-amino-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid —— C9H10N4O3S
    (2S)-2-[[4-amino-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
    —— (2S)-5-methyl-N-(2-pyrimidin-4-ylsulfanylethyl)hexan-2-amine —— C13H23N3S
    (2S)-5-methyl-N-(2-pyrimidin-4-ylsulfanylethyl)hexan-2-amine
    —— (2S)-1-[(R)-dodecylsulfinyl]propan-2-ol —— C15H32O2S
    (2S)-1-[(R)-dodecylsulfinyl]propan-2-ol
    —— 4-chloro-N'-hydroxy-2-pyrimidin-4-ylsulfanylbenzenecarboximidamide —— C11H9ClN4OS
    4-chloro-N'-hydroxy-2-pyrimidin-4-ylsulfanylbenzenecarboximidamide
    —— (2R)-1-[(S)-dodecylsulfinyl]propan-2-ol —— C15H32O2S
    (2R)-1-[(S)-dodecylsulfinyl]propan-2-ol
    —— (2S)-1-[(S)-dodecylsulfinyl]propan-2-ol —— C15H32O2S
    (2S)-1-[(S)-dodecylsulfinyl]propan-2-ol
    —— (2R)-5-methyl-N-(2-pyrimidin-4-ylsulfanylethyl)hexan-2-amine —— C13H23N3S
    (2R)-5-methyl-N-(2-pyrimidin-4-ylsulfanylethyl)hexan-2-amine
    —— (1S,2R,4R)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile —— C14H19N3S
    (1S,2R,4R)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile
    —— (1R,2R,4S)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile —— C14H19N3S
    (1R,2R,4S)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile
    —— (3R)-3-phenyl-3-pyrimidin-4-ylsulfanylpropanenitrile —— C13H11N3S
    (3R)-3-phenyl-3-pyrimidin-4-ylsulfanylpropanenitrile
    —— (1S,2R,4S)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile —— C14H19N3S
    (1S,2R,4S)-4-propyl-2-pyrimidin-4-ylsulfanylcyclohexane-1-carbonitrile
    —— (3S)-3-phenyl-3-pyrimidin-4-ylsulfanylpropanenitrile —— C13H11N3S
    (3S)-3-phenyl-3-pyrimidin-4-ylsulfanylpropanenitrile
    —— (1R,2S,4S)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2S,4S)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid
    —— (1R,2R)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine —— C14H16ClN3S
    (1R,2R)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine
    —— (2R)-2-(3-bromophenyl)-2-pyrimidin-4-ylsulfanylethanamine —— C12H12BrN3S
    (2R)-2-(3-bromophenyl)-2-pyrimidin-4-ylsulfanylethanamine
    —— 5-chloro-2-[(2R)-2-ethylhexyl]sulfanylaniline —— C14H22ClNS
    5-chloro-2-[(2R)-2-ethylhexyl]sulfanylaniline
    —— (1S,2R)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine —— C14H16ClN3S
    (1S,2R)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine
    —— (1S,2S)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine —— C14H16ClN3S
    (1S,2S)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine
    —— (1R)-1-[3-chloro-4-(2-chlorophenyl)sulfanylphenyl]-N-methylethanamine —— C15H15Cl2NS
    (1R)-1-[3-chloro-4-(2-chlorophenyl)sulfanylphenyl]-N-methylethanamine
    —— (1R,2R,4R)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2R,4R)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid
    —— (1R,2S)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine —— C14H16ClN3S
    (1R,2S)-1-(3-chlorophenyl)-1-pyrimidin-4-ylsulfanylbutan-2-amine
    —— (2S)-2-(3-bromophenyl)-2-pyrimidin-4-ylsulfanylethanamine —— C12H12BrN3S
    (2S)-2-(3-bromophenyl)-2-pyrimidin-4-ylsulfanylethanamine
    —— (1R,2S,4R)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2S,4R)-2-(2,4-dimethylphenyl)sulfanyl-4-methylcyclohexane-1-carboxylic acid
    —— 3-[(1S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]aniline —— C12H16N4S
    3-[(1S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]aniline
    —— (2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(3-methylphenyl)ethanamine —— C13H18N4S
    (2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(3-methylphenyl)ethanamine
    —— (1S)-1-[3-chloro-4-(2-chlorophenyl)sulfanylphenyl]-N-methylethanamine —— C15H15Cl2NS
    (1S)-1-[3-chloro-4-(2-chlorophenyl)sulfanylphenyl]-N-methylethanamine
    —— (1R)-1-(3-aminophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanol —— C12H16N4OS
    (1R)-1-(3-aminophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanol
    —— (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(3-methylphenyl)ethanamine —— C13H18N4S
    (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(3-methylphenyl)ethanamine
    —— 3-[(1R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]aniline —— C12H16N4S
    3-[(1R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]aniline
    —— (1R,2R,4R)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2R,4R)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid
    —— (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-pyridin-4-ylethanamine —— C11H15N5S
    (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-pyridin-4-ylethanamine
    —— (1S)-1-(3-aminophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanol —— C12H16N4OS
    (1S)-1-(3-aminophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanol
    —— (2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-pyridin-4-ylethanamine —— C11H15N5S
    (2R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-pyridin-4-ylethanamine
    —— (1R,2R,4S)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2R,4S)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid
    —— 4,6-dimethyl-2-[(1S,3R)-3-methylcyclohexyl]sulfanylpyridine-3-carbonitrile —— C15H20N2S
    4,6-dimethyl-2-[(1S,3R)-3-methylcyclohexyl]sulfanylpyridine-3-carbonitrile
    —— 4,6-dimethyl-2-[(1R,3S)-3-methylcyclohexyl]sulfanylpyridine-3-carbonitrile —— C15H20N2S
    4,6-dimethyl-2-[(1R,3S)-3-methylcyclohexyl]sulfanylpyridine-3-carbonitrile
    —— (1S,2R,4R)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1S,2R,4R)-2-phenylsulfanyl-4-propylcyclohexane-1-carboxylic acid