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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-(3-(phenylthio)propyl)-6,7-dihydro-1H-cyclopenta[c]pyridine-1,5(2H)-dione 1192046-60-8 C17H17NO2S
    4-(3-(phenylthio)propyl)-6,7-dihydro-1H-cyclopenta[c]pyridine-1,5(2H)-dione
    —— 1-chloro-4-(3-(phenylthio)propyl)-6,7-dihydro-5H-cyclopenta[c]pyridine 1192046-94-8 C17H18ClNS
    1-chloro-4-(3-(phenylthio)propyl)-6,7-dihydro-5H-cyclopenta[c]pyridine
    —— 1-chloro-4-(3-(phenylthio)propyl)-6,7-dihydro-5H-cyclopenta[c]pyridin-5-one 1192046-99-3 C17H16ClNOS
    1-chloro-4-(3-(phenylthio)propyl)-6,7-dihydro-5H-cyclopenta[c]pyridin-5-one
    —— 7-(phenylthio)-7-[dimethyl(phenyl)silyl]bicyclo[4.1.0]heptane 1246930-13-1 C21H26SSi
    7-(phenylthio)-7-[dimethyl(phenyl)silyl]bicyclo[4.1.0]heptane
    —— [(5S)-3,3-dimethoxy-5-methyl-6-phenylsulfanylhexoxy]-tri(propan-2-yl)silane 1201089-97-5 C24H44O3SSi
    [(5S)-3,3-dimethoxy-5-methyl-6-phenylsulfanylhexoxy]-tri(propan-2-yl)silane
    —— 3-benzylthio-4-methylfuroxan 1198084-57-9 C10H10N2O2S
    3-benzylthio-4-methylfuroxan
    —— 1-(4-(methylthio)oxazol-2-yl)-7-phenylheptan-1-ol 1096535-76-0 C17H23NO2S
    1-(4-(methylthio)oxazol-2-yl)-7-phenylheptan-1-ol
    —— 1-(4-(methylthio)oxazol-2-yl)-7-phenylheptan-1-one 1096535-77-1 C17H21NO2S
    1-(4-(methylthio)oxazol-2-yl)-7-phenylheptan-1-one
    —— 2-(4,6-bis((E)-2-(3,4-dibutylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(3,4-dibutylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole 1196715-08-8 C66H84S10
    2-(4,6-bis((E)-2-(3,4-dibutylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(3,4-dibutylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole
    —— 2-(4,6-bis((E)-2-(5-bromo-4-butylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(5-bromo-4-butylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole 1196715-09-9 C50H48Br4S10
    2-(4,6-bis((E)-2-(5-bromo-4-butylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(5-bromo-4-butylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole
    —— 2-(4,6-bis((E)-2-(5-bromo-4-octylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(5-bromo-4-octylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole 1196715-10-2 C66H80Br4S10
    2-(4,6-bis((E)-2-(5-bromo-4-octylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiol-2-ylidene)-4,6-bis((E)-2-(5-bromo-4-octylthiophen-2-yl)vinyl)thieno[3,4-d]-1,3-dithiole
    —— 2-(3-(1H-imidazol-2-ylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide 1057256-35-5 C17H12Cl2N4O4S3
    2-(3-(1H-imidazol-2-ylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide
    —— 2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(5-methylthiazol-2-yl)benzamide 1146340-50-2 C14H14N6OS2
    2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(5-methylthiazol-2-yl)benzamide
    —— 5-(1H-imidazol-2-ylthio)-2-amino-N-(4-methylthiazol-2-yl)benzamide 1146340-41-1 C14H13N5OS2
    5-(1H-imidazol-2-ylthio)-2-amino-N-(4-methylthiazol-2-yl)benzamide
    —— 2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-2-yl)benzamide 1146340-45-5 C15H14N6OS
    2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-2-yl)benzamide
    —— 2-amino-N-(4-methylthiazol-2-yl)-5-(pyridin-2-ylthio)benzamide 1146340-40-0 C16H14N4OS2
    2-amino-N-(4-methylthiazol-2-yl)-5-(pyridin-2-ylthio)benzamide
    —— 2-amino-N-(3-methyl-1,2,4-thiadiazol-5-yl)-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)benzamide 1146340-44-4 C13H13N7OS2
    2-amino-N-(3-methyl-1,2,4-thiadiazol-5-yl)-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)benzamide
    —— 2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(1,2,4-thiadiazol-5-yl)benzamide 1146340-43-3 C12H11N7OS2
    2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(1,2,4-thiadiazol-5-yl)benzamide
    —— 2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-3-yl)benzamide 1146340-46-6 C15H14N6OS
    2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-3-yl)benzamide
    —— 2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-4-yl)benzamide 1146340-47-7 C15H14N6OS
    2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(pyridin-4-yl)benzamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1124195-75-0 C24H16Cl2N2O4S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— 2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide 1057256-06-0 C20H12Cl3FN2O4S3
    2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide
    —— 2-(3-Hydroxy-2-(2-(phenylthio)acetamido)-2,3-dihydrothiazol-4-yl)acetic acid 1056651-83-2 C13H12N2O4S2
    2-(3-Hydroxy-2-(2-(phenylthio)acetamido)-2,3-dihydrothiazol-4-yl)acetic acid
    —— N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-48-0 C28H24N2O6S2
    N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(pyridin-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-22-0 C19H13Cl2N3O4S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(pyridin-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(1-methyl-1H-tetrazol-5-ylthio)-1H-indol-4-yloxy)acetamide 1057256-38-8 C16H12Cl2N6O4S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(1-methyl-1H-tetrazol-5-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(2-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-52-6 C26H19ClN2O4S2
    N-(2-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(3-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-54-8 C26H19ClN2O4S2
    N-(3-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(phenylthio)-1H-indol-4-yloxy)acetamide 1057256-18-4 C20H14Cl2N2O4S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(phenylthio)-1H-indol-4-yloxy)acetamide
    —— 2-(3-(benzo[d]thiazol-2-ylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide 1057256-13-9 C21H13Cl2N3O4S4
    2-(3-(benzo[d]thiazol-2-ylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide
    —— 2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(phenylsulfonyl)acetamide 1057256-42-4 C26H20N2O4S2
    2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(phenylsulfonyl)acetamide
    —— 2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide 1057256-08-2 C20H13Cl3N2O4S3
    2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(4-methoxyphenylthio)-1H-indol-4-yloxy)acetamide 1057256-20-8 C21H16Cl2N2O5S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(4-methoxyphenylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(3,4-dimethoxyphenylthio)-1H-indol-4-yloxy)acetamide 1057256-04-8 C22H18Cl2N2O6S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(3,4-dimethoxyphenylthio)-1H-indol-4-yloxy)acetamide
    —— N-(3,5-dichlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1124195-74-9 C26H18Cl2N2O4S2
    N-(3,5-dichlorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4-methoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-56-0 C27H22N2O5S2
    N-(4-methoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(5-chlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-39-9 C24H17ClN2O4S3
    N-(5-chlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(3,5-dimethylisoxazol-4-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057257-15-4 C25H21N3O5S2
    N-(3,5-dimethylisoxazol-4-ylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(3,5-difluorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide 1057256-66-2 C26H18F2N2O4S2
    N-(3,5-difluorophenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide
    —— N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,5-dimethoxyphenylthio)-1H-indol-4-yloxy)acetamide 1057256-14-0 C22H18Cl2N2O6S3
    N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,5-dimethoxyphenylthio)-1H-indol-4-yloxy)acetamide
    —— 2-(2-Methanesulfinyl-ethylamino)-ethanol 73761-83-8 C5H13NO2S
    2-(2-Methanesulfinyl-ethylamino)-ethanol
    —— (3S,4R,5R)-4,5-diallyl-3-phenylthio-dihydrofuran-2-one 920502-63-2 C16H18O2S
    (3S,4R,5R)-4,5-diallyl-3-phenylthio-dihydrofuran-2-one
    —— (3S,4R,5R)-4-allyl-5-(2-hydroxyethyl)-3-phenylthio-dihydrofuran-2-one 920502-62-1 C15H18O3S
    (3S,4R,5R)-4-allyl-5-(2-hydroxyethyl)-3-phenylthio-dihydrofuran-2-one
    —— (2R,3R,4S)-[5-oxo-4-(phenylthio)-2-(2-tert-butyldiphenylsilyloxy)ethyl-tetrahydrofuran-3-yl]acetic acid 920502-56-3 C30H34O5SSi
    (2R,3R,4S)-[5-oxo-4-(phenylthio)-2-(2-tert-butyldiphenylsilyloxy)ethyl-tetrahydrofuran-3-yl]acetic acid
    —— (3S,4R,5R)-4-(2-hydroxy-ethyl)-3-phenylthio-5-(2-tert-butyldiphenylsilyloxy)ethyl-dihydrofuran-2-one 920502-57-4 C30H36O4SSi
    (3S,4R,5R)-4-(2-hydroxy-ethyl)-3-phenylthio-5-(2-tert-butyldiphenylsilyloxy)ethyl-dihydrofuran-2-one
    —— (3S,4R,5R)-4-allyl-3-phenylthio-5-(2-tert-butyldiphenylsilyloxy)ethyl-dihydrofuran-2-one 920502-58-5 C31H36O3SSi
    (3S,4R,5R)-4-allyl-3-phenylthio-5-(2-tert-butyldiphenylsilyloxy)ethyl-dihydrofuran-2-one
    —— 2-methylthio-5-methyl-6-[1-hydroxy-1-(phenyl)methyl]cytosine 1093390-12-5 C13H15N3OS
    2-methylthio-5-methyl-6-[1-hydroxy-1-(phenyl)methyl]cytosine
    —— 2-methylthio-5-methyl-6-[1-chloro-1-(phenyl)methyl]cytosine 1093390-14-7 C13H14ClN3S
    2-methylthio-5-methyl-6-[1-chloro-1-(phenyl)methyl]cytosine
    —— Ethanamine, 2-[(1-butyl-3,5-dimethyl-1H-pyrazol-4-yl)thio]- 1429904-05-1 C11H21N3S
    Ethanamine, 2-[(1-butyl-3,5-dimethyl-1H-pyrazol-4-yl)thio]-
    —— 4-[2,6-dinitro-4-(trifluoromethyl)phenylsulfanyl]phenol 1137560-32-7 C13H7F3N2O5S
    4-[2,6-dinitro-4-(trifluoromethyl)phenylsulfanyl]phenol