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黄酮类化合物

黄酮类化合物 定义与结构特征

黄酮类化合物是一大类天然存在的有机化合物,属于酚类衍生物。它们的分子结构通常包含两个苯环(A和B环)和一个三碳环(C环),形成一个基本骨架。该骨架由多个亚结构组成,包括黄烷醇、黄酮、黄酮醇等。

生物来源

黄酮类化合物广泛存在于植物界中,常见于许多蔬菜、水果及中药中。例如,在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

化学性质 亲水性与溶解度

由于其分子结构中含有多个酚羟基,因此具有一定的亲水性和良好的溶解性,这使得黄酮类化合物在药物设计中扮演重要角色。

稳定性与光敏性

大多数黄酮类化合物相对稳定,在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感,容易被氧化,导致颜色变化。

生理活性与药用价值

黄酮类化合物因其丰富的生理活性而备受关注,主要包括:

  • 抗氧化作用:可有效清除体内自由基,保护细胞免受损伤。
  • 抗炎效应:有助于减轻炎症反应,缓解症状。
  • 心血管保护:可能通过多种机制改善心脑血管健康。
  • 抗癌潜力:研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
应用领域 食品工业

作为一种天然色素和抗氧化剂,被广泛应用于食品加工中以提高其保质期及营养价值。

化妆品行业

利用其良好的生物相容性和抗衰老特性,在化妆品配方中应用广泛。

药物开发

由于黄酮类化合物展现出广泛的药理活性,已成为新药研发的重要候选目标之一。

中文名称 英文名称 CAS号 化学式 结构式图片
—— (2S)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid —— C21H19ClO7
(2S)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid
—— (2S)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C20H16ClO6-
(2S)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— 6,8-Dichloro-2-phenyl-3-phenylmethoxychromen-4-one —— C22H14Cl2O3
6,8-Dichloro-2-phenyl-3-phenylmethoxychromen-4-one
—— 6-Chloro-3-[(4-fluorophenyl)methoxy]-7-methyl-2-phenylchromen-4-one —— C23H16ClFO3
6-Chloro-3-[(4-fluorophenyl)methoxy]-7-methyl-2-phenylchromen-4-one
—— (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C23H22ClO5-
(2S)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— 2-[6-Chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid —— C19H15ClO6
2-[6-Chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid
—— 6,8-Dichloro-3-ethoxy-2-phenylchromen-4-one —— C17H12Cl2O3
6,8-Dichloro-3-ethoxy-2-phenylchromen-4-one
—— (2S)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoic acid —— C18H12Cl2O5
(2S)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoic acid
—— [6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate —— C22H21ClO4
[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate
—— (2R)-2-[6,8-dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxypropanoate —— C19H13Cl2O5-
(2R)-2-[6,8-dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxypropanoate
—— (2S)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C21H18ClO7-
(2S)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— 6-Chloro-2-(4-chlorophenyl)-7-methyl-3-(2-oxopropoxy)chromen-4-one —— C19H14Cl2O4
6-Chloro-2-(4-chlorophenyl)-7-methyl-3-(2-oxopropoxy)chromen-4-one
—— (2R)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoic acid —— C18H12Cl2O5
(2R)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoic acid
—— [6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] pyridine-4-carboxylate —— C23H16ClNO4
[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] pyridine-4-carboxylate
—— [6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-methylbenzoate —— C25H19ClO4
[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-methylbenzoate
—— (2R)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid —— C21H19ClO7
(2R)-2-[6-chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid
—— 6-Chloro-3-methoxy-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C18H15ClO4
6-Chloro-3-methoxy-2-(4-methoxyphenyl)-7-methylchromen-4-one
—— 2-(6,8-Dichloro-4-oxo-2-phenylchromen-3-yl)oxyacetate —— C17H9Cl2O5-
2-(6,8-Dichloro-4-oxo-2-phenylchromen-3-yl)oxyacetate
—— (6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) pyridine-4-carboxylate —— C22H14ClNO4
(6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) pyridine-4-carboxylate
—— 6,8-Dichloro-3-methoxy-2-(4-methylphenyl)chromen-4-one —— C17H12Cl2O3
6,8-Dichloro-3-methoxy-2-(4-methylphenyl)chromen-4-one
—— [6-Chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl] prop-2-enyl carbonate —— C21H17ClO6
[6-Chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl] prop-2-enyl carbonate
—— methyl (2R)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoate —— C19H14Cl2O5
methyl (2R)-2-(6,8-dichloro-4-oxo-2-phenylchromen-3-yl)oxypropanoate
—— [6,8-Dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl] propanoate —— C19H14Cl2O4
[6,8-Dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl] propanoate
—— (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoic acid —— C23H23ClO5
(2S)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoic acid
—— 6-Chloro-7-methyl-2-phenyl-3-[(4-propan-2-ylphenyl)methoxy]chromen-4-one —— C26H23ClO3
6-Chloro-7-methyl-2-phenyl-3-[(4-propan-2-ylphenyl)methoxy]chromen-4-one
—— 6,8-Dichloro-3-ethoxy-2-(4-methylphenyl)chromen-4-one —— C18H14Cl2O3
6,8-Dichloro-3-ethoxy-2-(4-methylphenyl)chromen-4-one
—— [6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] thiophene-2-carboxylate —— C22H15ClO4S
[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl] thiophene-2-carboxylate
—— (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C23H22ClO5-
(2R)-2-[2-(4-tert-butylphenyl)-6-chloro-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— methyl (2R)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C21H19ClO6
methyl (2R)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— Methyl 2-[6-chloro-2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C19H14Cl2O5
Methyl 2-[6-chloro-2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
—— (6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) furan-2-carboxylate —— C21H13ClO5
(6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) furan-2-carboxylate
—— 6-Chloro-3-hydroxy-7-methyl-2-(4-methylphenyl)chromen-4-one —— C17H13ClO3
6-Chloro-3-hydroxy-7-methyl-2-(4-methylphenyl)chromen-4-one
—— 2-(6,8-Dichloro-4-oxo-2-phenylchromen-3-yl)oxyacetic acid —— C17H10Cl2O5
2-(6,8-Dichloro-4-oxo-2-phenylchromen-3-yl)oxyacetic acid
—— N-[(2S)-butan-2-yl]-2-(6-chloro-7-methyl-4-oxo-2-phenylchromen-3-yl)oxyacetamide —— C22H22ClNO4
N-[(2S)-butan-2-yl]-2-(6-chloro-7-methyl-4-oxo-2-phenylchromen-3-yl)oxyacetamide
—— 6-Chloro-3-ethoxy-7-methyl-2-phenylchromen-4-one —— C18H15ClO3
6-Chloro-3-ethoxy-7-methyl-2-phenylchromen-4-one
—— ethyl (2S)-2-[6-chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxypropanoate —— C22H21ClO5
ethyl (2S)-2-[6-chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxypropanoate
—— 6,8-Dichloro-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one —— C23H16Cl2O3
6,8-Dichloro-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one
—— Methyl 2-[6,8-dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate —— C19H14Cl2O5
Methyl 2-[6,8-dichloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate
—— methyl (2S)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C21H19ClO6
methyl (2S)-2-[6-chloro-2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate
—— 2-[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate —— C19H14ClO5-
2-[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetate
—— N-[(2S)-butan-2-yl]-2-[6-chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetamide —— C23H24ClNO4
N-[(2S)-butan-2-yl]-2-[6-chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetamide
—— 2-[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetonitrile —— C19H14ClNO3
2-[6-Chloro-7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetonitrile
—— 6-Chloro-7-methyl-3-(2-phenoxyethoxy)-2-phenylchromen-4-one —— C24H19ClO4
6-Chloro-7-methyl-3-(2-phenoxyethoxy)-2-phenylchromen-4-one
—— 6-Chloro-7-methyl-3-(2-oxopropoxy)-2-phenylchromen-4-one —— C19H15ClO4
6-Chloro-7-methyl-3-(2-oxopropoxy)-2-phenylchromen-4-one
—— 6-Chloro-7-methyl-2-phenyl-3-phenylmethoxychromen-4-one —— C23H17ClO3
6-Chloro-7-methyl-2-phenyl-3-phenylmethoxychromen-4-one
—— 6-Chloro-7-methyl-3-[2-(4-methylphenyl)-2-oxoethoxy]-2-phenylchromen-4-one —— C25H19ClO4
6-Chloro-7-methyl-3-[2-(4-methylphenyl)-2-oxoethoxy]-2-phenylchromen-4-one
—— 6-Chloro-7-methyl-3-(3-phenoxypropoxy)-2-phenylchromen-4-one —— C25H21ClO4
6-Chloro-7-methyl-3-(3-phenoxypropoxy)-2-phenylchromen-4-one
—— Propyl 2-(6-chloro-7-methyl-4-oxo-2-phenylchromen-3-yl)oxyacetate —— C21H19ClO5
Propyl 2-(6-chloro-7-methyl-4-oxo-2-phenylchromen-3-yl)oxyacetate
—— (6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) 2-fluorobenzoate —— C23H14ClFO4
(6-Chloro-7-methyl-4-oxo-2-phenylchromen-3-yl) 2-fluorobenzoate
—— 2-[6-Chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetonitrile —— C20H16ClNO5
2-[6-Chloro-2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetonitrile