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黄酮类化合物

黄酮类化合物 定义与结构特征

黄酮类化合物是一大类天然存在的有机化合物,属于酚类衍生物。它们的分子结构通常包含两个苯环(A和B环)和一个三碳环(C环),形成一个基本骨架。该骨架由多个亚结构组成,包括黄烷醇、黄酮、黄酮醇等。

生物来源

黄酮类化合物广泛存在于植物界中,常见于许多蔬菜、水果及中药中。例如,在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

化学性质 亲水性与溶解度

由于其分子结构中含有多个酚羟基,因此具有一定的亲水性和良好的溶解性,这使得黄酮类化合物在药物设计中扮演重要角色。

稳定性与光敏性

大多数黄酮类化合物相对稳定,在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感,容易被氧化,导致颜色变化。

生理活性与药用价值

黄酮类化合物因其丰富的生理活性而备受关注,主要包括:

  • 抗氧化作用:可有效清除体内自由基,保护细胞免受损伤。
  • 抗炎效应:有助于减轻炎症反应,缓解症状。
  • 心血管保护:可能通过多种机制改善心脑血管健康。
  • 抗癌潜力:研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
应用领域 食品工业

作为一种天然色素和抗氧化剂,被广泛应用于食品加工中以提高其保质期及营养价值。

化妆品行业

利用其良好的生物相容性和抗衰老特性,在化妆品配方中应用广泛。

药物开发

由于黄酮类化合物展现出广泛的药理活性,已成为新药研发的重要候选目标之一。

中文名称 英文名称 CAS号 化学式 结构式图片
—— [2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] benzoate —— C25H20O5
[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] benzoate
—— (2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoic acid —— C21H20O6
(2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoic acid
—— [2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2,2-dimethylpropanoate —— C22H21ClO4
[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2,2-dimethylpropanoate
—— [2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] furan-2-carboxylate —— C23H18O6
[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] furan-2-carboxylate
—— (2R)-2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C22H21O7-
(2R)-2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— methyl (2R)-2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C23H24O7
methyl (2R)-2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— [2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] (2S)-oxolane-2-carboxylate —— C23H22O6
[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] (2S)-oxolane-2-carboxylate
—— 3-Methoxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one —— C19H18O4
3-Methoxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one
—— 2-[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C20H17O6-
2-[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— 2-(4-Methoxyphenyl)-6,7-dimethyl-3-(2-oxopropoxy)chromen-4-one —— C21H20O5
2-(4-Methoxyphenyl)-6,7-dimethyl-3-(2-oxopropoxy)chromen-4-one
—— 2-(4-Methoxyphenyl)-6,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one —— C26H24O5
2-(4-Methoxyphenyl)-6,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one
—— [2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] acetate —— C20H18O5
[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] acetate
—— ethyl (2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C23H24O6
ethyl (2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— 2-[2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C21H19O7-
2-[2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— [2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] pyridine-4-carboxylate —— C23H16ClNO4
[2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] pyridine-4-carboxylate
—— 2-(2-Chlorophenyl)-6,7-dimethyl-3-[(4-methylphenyl)methoxy]chromen-4-one —— C25H21ClO3
2-(2-Chlorophenyl)-6,7-dimethyl-3-[(4-methylphenyl)methoxy]chromen-4-one
—— ethyl (2S)-2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C22H21ClO5
ethyl (2S)-2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— 2-(2-Chlorophenyl)-3-[(2-fluorophenyl)methoxy]-6,7-dimethylchromen-4-one —— C24H18ClFO3
2-(2-Chlorophenyl)-3-[(2-fluorophenyl)methoxy]-6,7-dimethylchromen-4-one
—— 2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-3-(2-oxopropoxy)chromen-4-one —— C22H22O6
2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-3-(2-oxopropoxy)chromen-4-one
—— 2-[2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetamide —— C21H21NO6
2-[2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetamide
—— 2-(4-Chlorophenyl)-6,7-dimethyl-3-[(2-methylphenyl)methoxy]chromen-4-one —— C25H21ClO3
2-(4-Chlorophenyl)-6,7-dimethyl-3-[(2-methylphenyl)methoxy]chromen-4-one
—— (2S)-2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C20H16ClO5-
(2S)-2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— methyl (2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C22H22O6
methyl (2R)-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— 3-[(2-Chlorophenyl)methoxy]-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one —— C25H21ClO4
3-[(2-Chlorophenyl)methoxy]-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one
—— Methyl 2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C21H20O6
Methyl 2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— Ethyl 2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C21H19ClO5
Ethyl 2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— [2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2-methylpropyl carbonate —— C22H21ClO5
[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2-methylpropyl carbonate
—— (2R)-2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate —— C20H16ClO5-
(2R)-2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoate
—— 3-[(3,5-Dimethyl-1,2-oxazol-4-yl)methoxy]-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one —— C24H23NO5
3-[(3,5-Dimethyl-1,2-oxazol-4-yl)methoxy]-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one
—— Methyl 2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C20H17ClO5
Methyl 2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— 2-[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetic acid —— C20H18O6
2-[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetic acid
—— 2-(4-Methoxyphenyl)-6,7-dimethyl-3-(3-phenylpropoxy)chromen-4-one —— C27H26O4
2-(4-Methoxyphenyl)-6,7-dimethyl-3-(3-phenylpropoxy)chromen-4-one
—— 2-[[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxymethyl]benzonitrile —— C25H18ClNO3
2-[[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxymethyl]benzonitrile
—— [2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] 3-methylbutanoate —— C24H26O6
[2-(3,4-Dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] 3-methylbutanoate
—— N-[(2R)-butan-2-yl]-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetamide —— C24H27NO5
N-[(2R)-butan-2-yl]-2-[2-(4-methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetamide
—— [2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] methanesulfonate —— C18H15ClO5S
[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] methanesulfonate
—— 2-(2-Chlorophenyl)-3-[(4-fluorophenyl)methoxy]-6,7-dimethylchromen-4-one —— C24H18ClFO3
2-(2-Chlorophenyl)-3-[(4-fluorophenyl)methoxy]-6,7-dimethylchromen-4-one
—— [2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2-methylbenzoate —— C25H19ClO4
[2-(4-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] 2-methylbenzoate
—— 3-Ethoxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one —— C20H20O4
3-Ethoxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one
—— [2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate —— C23H18O5S
[2-(4-Methoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl] thiophene-2-carboxylate
—— 2-(4-Chlorophenyl)-3-hydroxy-6,7-dimethylchromen-4-one —— C17H13ClO3
2-(4-Chlorophenyl)-3-hydroxy-6,7-dimethylchromen-4-one
—— (2R)-2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoic acid —— C20H17ClO5
(2R)-2-[2-(2-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxypropanoic acid
—— 2-(3,4-Dimethoxyphenyl)-3-ethoxy-6,7-dimethylchromen-4-one —— C21H22O5
2-(3,4-Dimethoxyphenyl)-3-ethoxy-6,7-dimethylchromen-4-one
—— Ethyl 2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C23H24O7
Ethyl 2-[2-(3,4-dimethoxyphenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— 3-Hydroxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one —— C18H16O4
3-Hydroxy-2-(4-methoxyphenyl)-6,7-dimethylchromen-4-one
—— Methyl 2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate —— C20H17ClO5
Methyl 2-[2-(4-chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxyacetate
—— 2-(4-Chlorophenyl)-3-(methoxymethoxy)-6,7-dimethylchromen-4-one —— C19H17ClO4
2-(4-Chlorophenyl)-3-(methoxymethoxy)-6,7-dimethylchromen-4-one
—— 2-(2-Chlorophenyl)-3-methoxy-6,7-dimethylchromen-4-one —— C18H15ClO3
2-(2-Chlorophenyl)-3-methoxy-6,7-dimethylchromen-4-one
—— 2-[[2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxymethyl]benzonitrile —— C25H18ClNO3
2-[[2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl]oxymethyl]benzonitrile
—— [2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] furan-2-carboxylate —— C22H15ClO5
[2-(2-Chlorophenyl)-6,7-dimethyl-4-oxochromen-3-yl] furan-2-carboxylate