摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 3-[1-adamantylmethyl(3-methylbut-2-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide 6106-13-4 C33H42N2O7
    3-[1-adamantylmethyl(3-methylbut-2-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(pent-2-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C33H42N2O7
    3-[1-adamantylmethyl(pent-2-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(dodecanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C40H58N2O7
    3-[1-adamantylmethyl(dodecanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(octanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C36H50N2O7
    3-[1-adamantylmethyl(octanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl-(2-methoxyacetyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C31H40N2O8
    3-[1-adamantylmethyl-(2-methoxyacetyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(hept-6-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C35H46N2O7
    3-[1-adamantylmethyl(hept-6-enoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(3-methylbutanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C33H44N2O7
    3-[1-adamantylmethyl(3-methylbutanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(2-methylpropanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C32H42N2O7
    3-[1-adamantylmethyl(2-methylpropanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[1-adamantylmethyl(butanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C32H42N2O7
    3-[1-adamantylmethyl(butanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2R)-2-(4-methoxyphenyl)-2-pyrrolidin-1-ylethyl]acetamide —— C23H28N2O3
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2R)-2-(4-methoxyphenyl)-2-pyrrolidin-1-ylethyl]acetamide
    —— N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]acetamide —— C20H20N2O3S
    N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]acetamide
    —— (3S)-3-[[(2R)-2-methylbutyl]amino]-2,3-dihydro-1-benzofuran-6-ol —— C13H19NO2
    (3S)-3-[[(2R)-2-methylbutyl]amino]-2,3-dihydro-1-benzofuran-6-ol
    —— (3R)-3-[[(2R)-2-methylbutyl]amino]-2,3-dihydro-1-benzofuran-6-ol —— C13H19NO2
    (3R)-3-[[(2R)-2-methylbutyl]amino]-2,3-dihydro-1-benzofuran-6-ol
    —— 4-amino-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1,2,5-oxadiazole-3-carboxamide —— C12H12N4O3
    4-amino-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1,2,5-oxadiazole-3-carboxamide
    —— (3S)-3-[2-aminoethyl(methyl)amino]-2,3-dihydro-1-benzofuran-6-ol —— C11H16N2O2
    (3S)-3-[2-aminoethyl(methyl)amino]-2,3-dihydro-1-benzofuran-6-ol
    —— (1R)-1-(2,2-dimethyl-3H-1-benzofuran-5-yl)-N,2,2-trimethylbutan-1-amine —— C17H27NO
    (1R)-1-(2,2-dimethyl-3H-1-benzofuran-5-yl)-N,2,2-trimethylbutan-1-amine
    —— (1S)-1-(2,2-dimethyl-3H-1-benzofuran-5-yl)-N,2,2-trimethylbutan-1-amine —— C17H27NO
    (1S)-1-(2,2-dimethyl-3H-1-benzofuran-5-yl)-N,2,2-trimethylbutan-1-amine
    —— (1R)-N-ethyl-2,2-dimethyl-1-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]butan-1-amine —— C17H27NO
    (1R)-N-ethyl-2,2-dimethyl-1-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]butan-1-amine
    —— [(2R)-2,3-dihydro-1-benzofuran-2-yl]-[(2R)-2-methylpiperazin-1-yl]methanone —— C14H18N2O2
    [(2R)-2,3-dihydro-1-benzofuran-2-yl]-[(2R)-2-methylpiperazin-1-yl]methanone
    —— (2R,3S)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine —— C10H12ClNO
    (2R,3S)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— (3S)-7-chloro-5-methyl-2,3-dihydro-1-benzofuran-3-amine —— C9H10ClNO
    (3S)-7-chloro-5-methyl-2,3-dihydro-1-benzofuran-3-amine
    —— (3R)-7-chloro-N,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine —— C10H12ClNO
    (3R)-7-chloro-N,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— (3R)-7-chloro-5-methyl-2,3-dihydro-1-benzofuran-3-amine —— C9H10ClNO
    (3R)-7-chloro-5-methyl-2,3-dihydro-1-benzofuran-3-amine
    —— (2S,3R)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine —— C10H12ClNO
    (2S,3R)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— (2R,3S)-7-chloro-N,2,5-trimethyl-2,3-dihydro-1-benzofuran-3-amine —— C11H14ClNO
    (2R,3S)-7-chloro-N,2,5-trimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— (2S,3S)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine —— C10H12ClNO
    (2S,3S)-7-chloro-2,5-dimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— (2S,3R)-7-chloro-N,2,5-trimethyl-2,3-dihydro-1-benzofuran-3-amine —— C11H14ClNO
    (2S,3R)-7-chloro-N,2,5-trimethyl-2,3-dihydro-1-benzofuran-3-amine
    —— 2-(2,3-Dihydro-1-benzofuran-5-yl)-3-(3-methylsulfanylpropyl)-1,3-thiazolidin-4-one —— C15H19NO2S2
    2-(2,3-Dihydro-1-benzofuran-5-yl)-3-(3-methylsulfanylpropyl)-1,3-thiazolidin-4-one
    —— 3-[1-adamantylmethyl(oxolane-2-carbonyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C33H42N2O8
    3-[1-adamantylmethyl(oxolane-2-carbonyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (R)-(2,3-difluorophenyl)-(2,3-dihydro-1-benzofuran-5-yl)methanamine —— C15H13F2NO
    (R)-(2,3-difluorophenyl)-(2,3-dihydro-1-benzofuran-5-yl)methanamine
    —— (2S)-1-[5-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine —— C14H17N3O2
    (2S)-1-[5-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine
    —— (2S)-3-(2,3-dihydro-1-benzofuran-5-ylmethylamino)-2-methylpropanenitrile —— C13H16N2O
    (2S)-3-(2,3-dihydro-1-benzofuran-5-ylmethylamino)-2-methylpropanenitrile
    —— (2R)-1-[5-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine —— C14H17N3O2
    (2R)-1-[5-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine
    —— (2S)-3-[[(3R)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]amino]-2-methylpropanenitrile —— C12H14N2O2
    (2S)-3-[[(3R)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]amino]-2-methylpropanenitrile
    —— (2R)-1-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine —— C14H17N3O2
    (2R)-1-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine
    —— (2S)-1-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine —— C14H17N3O2
    (2S)-1-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine
    —— (2R)-3-[[(3R)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]amino]-2-methylpropanenitrile —— C12H14N2O2
    (2R)-3-[[(3R)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]amino]-2-methylpropanenitrile
    —— (1S)-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1-(2-methoxyphenyl)-1-(1-methylimidazol-2-yl)methanamine —— C21H23N3O2
    (1S)-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1-(2-methoxyphenyl)-1-(1-methylimidazol-2-yl)methanamine
    —— 3-[butanoyl-[(3,4-dichlorophenyl)methyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C28H32Cl2N2O7
    3-[butanoyl-[(3,4-dichlorophenyl)methyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[3-cyclopentylpropanoyl(2,2,2-trifluoroethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C27H35F3N2O7
    3-[3-cyclopentylpropanoyl(2,2,2-trifluoroethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[(3,4-dichlorophenyl)methyl-dodecanoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C36H48Cl2N2O7
    3-[(3,4-dichlorophenyl)methyl-dodecanoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (2S)-N-[(3R)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C14H20N2O2
    (2S)-N-[(3R)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2R)-N-[(3R)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C14H20N2O2
    (2R)-N-[(3R)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2S)-N-[(3S)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C14H20N2O2
    (2S)-N-[(3S)-1-aminopentan-3-yl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2R)-1-[5-(2,3-dihydro-1-benzofuran-5-yl)-1,2,4-oxadiazol-3-yl]propan-2-amine —— C13H15N3O2
    (2R)-1-[5-(2,3-dihydro-1-benzofuran-5-yl)-1,2,4-oxadiazol-3-yl]propan-2-amine
    —— 3-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine —— C13H15N3O2
    3-[5-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine
    —— (2R)-N-(3-cyanopropyl)-2,3-dihydro-1-benzofuran-2-carboxamide —— C13H14N2O2
    (2R)-N-(3-cyanopropyl)-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2R)-N-[(4Z)-4-amino-4-hydroxyiminobutyl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C13H17N3O3
    (2R)-N-[(4Z)-4-amino-4-hydroxyiminobutyl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2S)-N-(4-amino-4-sulfanylidenebutyl)-2,3-dihydro-1-benzofuran-2-carboxamide —— C13H16N2O2S
    (2S)-N-(4-amino-4-sulfanylidenebutyl)-2,3-dihydro-1-benzofuran-2-carboxamide
    —— 3-[dodecanoyl-[(2-fluorophenyl)methyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C34H45FN2O5
    3-[dodecanoyl-[(2-fluorophenyl)methyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide