摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-3-(1-pyridin-2-ylpiperidin-4-yl)urea —— C23H30N4O3
    1-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-3-(1-pyridin-2-ylpiperidin-4-yl)urea
    —— 1-(1-cyclopropylpiperidin-4-yl)-3-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]urea —— C21H31N3O3
    1-(1-cyclopropylpiperidin-4-yl)-3-[[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]urea
    —— 1-[[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-3-(1-pyridin-2-ylpiperidin-4-yl)urea —— C23H30N4O3
    1-[[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]methyl]-3-(1-pyridin-2-ylpiperidin-4-yl)urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[4-(morpholin-4-ylmethyl)phenyl]methyl]urea —— C22H27N3O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[4-(morpholin-4-ylmethyl)phenyl]methyl]urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[4-(morpholin-4-ylmethyl)phenyl]methyl]urea —— C22H27N3O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[4-(morpholin-4-ylmethyl)phenyl]methyl]urea
    —— [4-(2,3-dihydro-1-benzofuran-5-ylmethyl)piperazin-1-yl]-[(2R)-1,4-dioxan-2-yl]methanone —— C18H24N2O4
    [4-(2,3-dihydro-1-benzofuran-5-ylmethyl)piperazin-1-yl]-[(2R)-1,4-dioxan-2-yl]methanone
    —— [4-(2,3-dihydro-1-benzofuran-5-ylmethyl)piperazin-1-yl]-[(2S)-1,4-dioxan-2-yl]methanone —— C18H24N2O4
    [4-(2,3-dihydro-1-benzofuran-5-ylmethyl)piperazin-1-yl]-[(2S)-1,4-dioxan-2-yl]methanone
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-pyrrolidin-1-ylpyridin-3-yl)urea —— C19H22N4O2
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-pyrrolidin-1-ylpyridin-3-yl)urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-pyrrolidin-1-ylpyridin-3-yl)urea —— C19H22N4O2
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-pyrrolidin-1-ylpyridin-3-yl)urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-morpholin-4-ylpyridin-3-yl)urea —— C19H22N4O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-morpholin-4-ylpyridin-3-yl)urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-morpholin-4-ylpyridin-3-yl)urea —— C19H22N4O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(6-morpholin-4-ylpyridin-3-yl)urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-ethylpiperidin-4-yl)urea —— C17H25N3O2
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-ethylpiperidin-4-yl)urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-ethylpiperidin-4-yl)urea —— C17H25N3O2
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-ethylpiperidin-4-yl)urea
    —— (2R)-5-chloro-N-[2-[[3-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C17H15ClF3N3O2
    (2R)-5-chloro-N-[2-[[3-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2S)-5-chloro-N-[2-[[3-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C17H15ClF3N3O2
    (2S)-5-chloro-N-[2-[[3-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (3R)-5-ethyl-3-phenyl-3H-1-benzofuran-2-one —— C16H14O2
    (3R)-5-ethyl-3-phenyl-3H-1-benzofuran-2-one
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-methylpiperidin-4-yl)urea —— C16H23N3O2
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-methylpiperidin-4-yl)urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-methylpiperidin-4-yl)urea —— C16H23N3O2
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(1-methylpiperidin-4-yl)urea
    —— (2R)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]propanenitrile —— C13H15NO2
    (2R)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]propanenitrile
    —— (2S)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]propanenitrile —— C13H15NO2
    (2S)-2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]propanenitrile
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea —— C18H23N3O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea —— C18H23N3O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea —— C18H23N3O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(dimethylamino)-2-(furan-2-yl)ethyl]urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea —— C21H27N3O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea —— C21H27N3O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea —— C21H27N3O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2R)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea —— C21H27N3O3
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(2S)-2-(furan-2-yl)-2-piperidin-1-ylethyl]urea
    —— 1-[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]ethyl]-3-[(2R)-2-hydroxypropyl]urea —— C16H24N2O4
    1-[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]ethyl]-3-[(2R)-2-hydroxypropyl]urea
    —— 1-(3-butoxypropyl)-3-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]urea —— C17H26N2O3
    1-(3-butoxypropyl)-3-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]urea
    —— 1-(3-butoxypropyl)-3-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]urea —— C17H26N2O3
    1-(3-butoxypropyl)-3-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]urea
    —— 1-[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]ethyl]-3-[(2S)-2-hydroxypropyl]urea —— C16H24N2O4
    1-[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]ethyl]-3-[(2S)-2-hydroxypropyl]urea
    —— (5Z)-3-[(4-fluorophenyl)methyl]-5-[[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one —— C20H16FNO2S2
    (5Z)-3-[(4-fluorophenyl)methyl]-5-[[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
    —— N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-(6-methylpyridin-3-yl)acetamide —— C17H18N2O2
    N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-(6-methylpyridin-3-yl)acetamide
    —— N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-(6-methylpyridin-3-yl)acetamide —— C17H18N2O2
    N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-(6-methylpyridin-3-yl)acetamide
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(3-imidazol-1-ylpropyl)urea —— C16H20N4O2
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(3-imidazol-1-ylpropyl)urea
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3S)-1,1-dioxothiolan-3-yl]urea —— C14H18N2O4S
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3S)-1,1-dioxothiolan-3-yl]urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(pyridin-2-ylmethyl)urea —— C16H17N3O2
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(pyridin-2-ylmethyl)urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3S)-1,1-dioxothiolan-3-yl]urea —— C14H18N2O4S
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3S)-1,1-dioxothiolan-3-yl]urea
    —— 1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3R)-1,1-dioxothiolan-3-yl]urea —— C14H18N2O4S
    1-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[(3R)-1,1-dioxothiolan-3-yl]urea
    —— 6-[(5E)-5-[[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid —— C19H21NO4S2
    6-[(5E)-5-[[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[(2R)-oxolan-2-yl]methyl]urea —— C15H20N2O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[[(2R)-oxolan-2-yl]methyl]urea
    —— (2S)-N-[(1R)-1-[3-methoxy-4-(2-methylpropoxy)phenyl]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide —— C22H27NO4
    (2S)-N-[(1R)-1-[3-methoxy-4-(2-methylpropoxy)phenyl]ethyl]-2,3-dihydro-1-benzofuran-2-carboxamide
    —— 1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(2-methoxyethyl)urea —— C13H18N2O3
    1-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-(2-methoxyethyl)urea
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2S,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide —— C24H30N2O3
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2S,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2R,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide —— C24H30N2O3
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2R,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide —— C24H30N2O3
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[[4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]methyl]acetamide
    —— (3R)-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide —— C17H18F3N3O3
    (3R)-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide
    —— (3R)-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide —— C17H18F3N3O3
    (3R)-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide
    —— (3S)-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide —— C17H18F3N3O3
    (3S)-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide
    —— (3S)-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide —— C17H18F3N3O3
    (3S)-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butanamide