摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (3S)-3-[[(2S)-2-(dimethylamino)propyl]amino]-2,3-dihydro-1-benzofuran-6-ol —— C13H20N2O2
    (3S)-3-[[(2S)-2-(dimethylamino)propyl]amino]-2,3-dihydro-1-benzofuran-6-ol
    —— (3R)-3-[[(2S)-2-(dimethylamino)propyl]amino]-2,3-dihydro-1-benzofuran-6-ol —— C13H20N2O2
    (3R)-3-[[(2S)-2-(dimethylamino)propyl]amino]-2,3-dihydro-1-benzofuran-6-ol
    —— (2S)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)propyl]-2-N,2-N-dimethylpropane-1,2-diamine —— C16H26N2O
    (2S)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)propyl]-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2R)-1-N-[(1R)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine —— C15H24N2O
    (2R)-1-N-[(1R)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2R)-1-N-[(1R)-1-(2,3-dihydro-1-benzofuran-5-yl)propyl]-2-N,2-N-dimethylpropane-1,2-diamine —— C16H26N2O
    (2R)-1-N-[(1R)-1-(2,3-dihydro-1-benzofuran-5-yl)propyl]-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2R)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine —— C15H24N2O
    (2R)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2S)-1-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-2-N,2-N-dimethylpropane-1,2-diamine —— C14H22N2O
    (2S)-1-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2S)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine —— C15H24N2O
    (2S)-1-N-[(1S)-1-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-2-N,2-N-dimethylpropane-1,2-diamine
    —— (2R)-1-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-2-N,2-N-dimethylpropane-1,2-diamine —— C14H22N2O
    (2R)-1-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-2-N,2-N-dimethylpropane-1,2-diamine
    —— (3R)-3-(1,4-diazepan-1-yl)-2,3-dihydro-1-benzofuran-6-ol —— C13H18N2O2
    (3R)-3-(1,4-diazepan-1-yl)-2,3-dihydro-1-benzofuran-6-ol
    —— (3S)-3-(1,4-diazepan-1-yl)-2,3-dihydro-1-benzofuran-6-ol —— C13H18N2O2
    (3S)-3-(1,4-diazepan-1-yl)-2,3-dihydro-1-benzofuran-6-ol
    —— (2S)-2-(azepan-1-yl)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile —— C16H20N2O
    (2S)-2-(azepan-1-yl)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile
    —— (3R)-3-(azepan-1-yl)-6-hydroxy-2H-1-benzofuran-3-carbonitrile —— C15H18N2O2
    (3R)-3-(azepan-1-yl)-6-hydroxy-2H-1-benzofuran-3-carbonitrile
    —— (3R)-3-[[(3S)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol —— C13H17NO4S
    (3R)-3-[[(3S)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol
    —— (3R)-3-[[(3R)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol —— C13H17NO4S
    (3R)-3-[[(3R)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol
    —— 4-hydroxy-N-(2-hydroxyethyl)-3-[2-(2-methoxyphenyl)ethyl-(5-oxohexanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C30H36N2O7
    4-hydroxy-N-(2-hydroxyethyl)-3-[2-(2-methoxyphenyl)ethyl-(5-oxohexanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[cyclobutanecarbonyl(3-propan-2-yloxypropyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C26H36N2O6
    3-[cyclobutanecarbonyl(3-propan-2-yloxypropyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (3S)-3-[[(3S)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol —— C13H17NO4S
    (3S)-3-[[(3S)-1,1-dioxothiolan-3-yl]methylamino]-2,3-dihydro-1-benzofuran-6-ol
    —— 3-[cyclobutanecarbonyl(oxolan-2-ylmethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C27H36N2O8
    3-[cyclobutanecarbonyl(oxolan-2-ylmethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— [4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine —— C16H17NO
    [4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine
    —— [2-fluoro-4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine —— C16H16FNO
    [2-fluoro-4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine
    —— (1R)-1-[3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine —— C17H19NO
    (1R)-1-[3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine
    —— [4-fluoro-3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine —— C16H16FNO
    [4-fluoro-3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine
    —— [4-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine —— C16H17NO
    [4-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine
    —— (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine —— C17H19NO
    (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine
    —— [2-fluoro-4-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine —— C16H16FNO
    [2-fluoro-4-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]methanamine
    —— (1R)-1-[2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine —— C17H19NO
    (1R)-1-[2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine
    —— 2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H14O2
    2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— (1R)-1-[3-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine —— C16H17NO
    (1R)-1-[3-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine
    —— (1R)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine —— C16H17NO
    (1R)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine
    —— (1S)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine —— C16H17NO
    (1S)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine
    —— (1S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine —— C16H17NO
    (1S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine
    —— (1S)-1-[2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine —— C17H19NO
    (1S)-1-[2-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine
    —— (1R)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine —— C17H19NO
    (1R)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine
    —— 2-fluoro-5-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H13FO2
    2-fluoro-5-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— (1S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine —— C17H19NO
    (1S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine
    —— (1S)-1-[3-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine —— C17H19NO
    (1S)-1-[3-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine
    —— (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine —— C16H17NO
    (1R)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]ethanamine
    —— (1S)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine —— C17H19NO
    (1S)-1-[4-(2,3-dihydro-1-benzofuran-5-yl)phenyl]-N-methylethanamine
    —— (1S)-1-[3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine —— C17H19NO
    (1S)-1-[3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]phenyl]ethanamine
    —— 4-fluoro-3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H13FO2
    4-fluoro-3-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 2-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H14O2
    2-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 2-fluoro-4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H13FO2
    2-fluoro-4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3-[oxolane-3-carbonyl(oxolan-2-ylmethyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C27H36N2O9
    4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3-[oxolane-3-carbonyl(oxolan-2-ylmethyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H14O2
    3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 4-fluoro-3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H13FO2
    4-fluoro-3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde —— C16H14O2
    4-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzaldehyde
    —— 4-fluoro-2-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]aniline —— C15H14FNO
    4-fluoro-2-[(2S)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]aniline
    —— 2-methyl-5-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]aniline —— C16H17NO
    2-methyl-5-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]aniline
    —— 3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzoic acid —— C16H14O3
    3-[(2R)-2-methyl-2,3-dihydro-1-benzofuran-5-yl]benzoic acid