摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (1R)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-[(4-methyl-1,2,4-triazol-3-yl)methyl]ethanamine —— C14H18N4O
    (1R)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-[(4-methyl-1,2,4-triazol-3-yl)methyl]ethanamine
    —— (3R)-3-[(4-methyl-1,2,4-triazol-3-yl)methylamino]-2,3-dihydro-1-benzofuran-6-ol —— C12H14N4O2
    (3R)-3-[(4-methyl-1,2,4-triazol-3-yl)methylamino]-2,3-dihydro-1-benzofuran-6-ol
    —— (2R)-N-(1H-pyrazol-4-ylmethyl)-2,3-dihydro-1-benzofuran-2-carboxamide —— C13H13N3O2
    (2R)-N-(1H-pyrazol-4-ylmethyl)-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (2S)-N-(1H-pyrazol-4-ylmethyl)-2,3-dihydro-1-benzofuran-2-carboxamide —— C13H13N3O2
    (2S)-N-(1H-pyrazol-4-ylmethyl)-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (1R)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-(1H-pyrazol-4-ylmethyl)ethanamine —— C14H17N3O
    (1R)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-(1H-pyrazol-4-ylmethyl)ethanamine
    —— (1S)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-(1H-pyrazol-4-ylmethyl)ethanamine —— C14H17N3O
    (1S)-1-(2,3-dihydro-1-benzofuran-5-yl)-N-(1H-pyrazol-4-ylmethyl)ethanamine
    —— (3R)-3-(1H-pyrazol-4-ylmethylamino)-2,3-dihydro-1-benzofuran-6-ol —— C12H13N3O2
    (3R)-3-(1H-pyrazol-4-ylmethylamino)-2,3-dihydro-1-benzofuran-6-ol
    —— 1-[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-N-(1H-pyrazol-4-ylmethyl)methanamine —— C16H21N3O2
    1-[(2R)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-N-(1H-pyrazol-4-ylmethyl)methanamine
    —— (3S)-3-(1H-pyrazol-4-ylmethylamino)-2,3-dihydro-1-benzofuran-6-ol —— C12H13N3O2
    (3S)-3-(1H-pyrazol-4-ylmethylamino)-2,3-dihydro-1-benzofuran-6-ol
    —— 1-[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-N-(1H-pyrazol-4-ylmethyl)methanamine —— C16H21N3O2
    1-[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-N-(1H-pyrazol-4-ylmethyl)methanamine
    —— N-[(1S)-1-(5-bromothiophen-2-yl)ethyl]-2,3-dihydro-1-benzofuran-5-amine —— C14H14BrNOS
    N-[(1S)-1-(5-bromothiophen-2-yl)ethyl]-2,3-dihydro-1-benzofuran-5-amine
    —— N-[(1R)-1-(5-bromothiophen-2-yl)ethyl]-2,3-dihydro-1-benzofuran-5-amine —— C14H14BrNOS
    N-[(1R)-1-(5-bromothiophen-2-yl)ethyl]-2,3-dihydro-1-benzofuran-5-amine
    —— 1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4,5-dimethyl-1,2,4-triazol-3-yl)methyl]methanamine —— C14H18N4O
    1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4,5-dimethyl-1,2,4-triazol-3-yl)methyl]methanamine
    —— 1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4,5-dimethyl-1,2,4-triazol-3-yl)methyl]methanamine —— C14H18N4O
    1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4,5-dimethyl-1,2,4-triazol-3-yl)methyl]methanamine
    —— N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1H-pyrazole-4-carboxamide —— C13H13N3O2
    N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1H-pyrazole-4-carboxamide
    —— 1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-(furan-2-ylmethyl)methanamine —— C14H15NO2
    1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-(furan-2-ylmethyl)methanamine
    —— 2-[[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]acetyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide —— C22H26N2O4S
    2-[[2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]acetyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
    —— 4-bromo-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1-methylpyrrole-2-carboxamide —— C15H15BrN2O2
    4-bromo-N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1-methylpyrrole-2-carboxamide
    —— 3-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methylamino]propanenitrile —— C12H14N2O
    3-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methylamino]propanenitrile
    —— 3-[[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methylamino]methyl]benzonitrile —— C17H16N2O
    3-[[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methylamino]methyl]benzonitrile
    —— 3-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methylamino]propanenitrile —— C12H14N2O
    3-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methylamino]propanenitrile
    —— 1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-(thiophen-2-ylmethyl)methanamine —— C14H15NOS
    1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-(thiophen-2-ylmethyl)methanamine
    —— 1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-(thiophen-2-ylmethyl)methanamine —— C14H15NOS
    1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-(thiophen-2-ylmethyl)methanamine
    —— 3-[cyclopropanecarbonyl(2-morpholin-4-ylethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C27H37N3O8
    3-[cyclopropanecarbonyl(2-morpholin-4-ylethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 4-bromo-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1-methylpyrrole-2-carboxamide —— C15H15BrN2O2
    4-bromo-N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-1-methylpyrrole-2-carboxamide
    —— N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-methylpropan-1-amine —— C13H19NO
    N-[[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2-methylpropan-1-amine
    —— 1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[(3-methylthiophen-2-yl)methyl]methanamine —— C15H17NOS
    1-[(2R)-2,3-dihydro-1-benzofuran-2-yl]-N-[(3-methylthiophen-2-yl)methyl]methanamine
    —— 1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(3-methylthiophen-2-yl)methyl]methanamine —— C15H17NOS
    1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(3-methylthiophen-2-yl)methyl]methanamine
    —— 1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4-fluorophenyl)methyl]methanamine —— C16H16FNO
    1-[(2S)-2,3-dihydro-1-benzofuran-2-yl]-N-[(4-fluorophenyl)methyl]methanamine
    —— 3-[cycloheptyl(cyclopropanecarbonyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C26H34N2O5
    3-[cycloheptyl(cyclopropanecarbonyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3-[2-morpholin-4-ylethyl(oxolane-3-carbonyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C28H37N3O9
    8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3-[2-morpholin-4-ylethyl(oxolane-3-carbonyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[acetyl(cycloheptyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C26H34N2O7
    3-[acetyl(cycloheptyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[cyclohexylmethyl(3-cyclopentylpropanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C32H46N2O7
    3-[cyclohexylmethyl(3-cyclopentylpropanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-1,3-thiazole-4-carbaldehyde —— C15H15NO3S
    2-[(2S)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl]-1,3-thiazole-4-carbaldehyde
    —— 3-[cyclopentyl(3-cyclopentylpropanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C28H38N2O5
    3-[cyclopentyl(3-cyclopentylpropanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2,2,2-trifluoroethanamine —— C11H12F3NO
    N-[[(2R)-2,3-dihydro-1-benzofuran-2-yl]methyl]-2,2,2-trifluoroethanamine
    —— 3-[cycloheptyl-(2-cyclopentylacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C29H40N2O5
    3-[cycloheptyl-(2-cyclopentylacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[(2-cyclopentylacetyl)-(2-morpholin-4-ylethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C30H43N3O8
    3-[(2-cyclopentylacetyl)-(2-morpholin-4-ylethyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(2,2,2-trifluoroethylamino)acetonitrile —— C12H11F3N2O
    (2R)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(2,2,2-trifluoroethylamino)acetonitrile
    —— 3-[1-adamantylmethyl(3-methylbut-2-enoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C31H40N2O5
    3-[1-adamantylmethyl(3-methylbut-2-enoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(2,2,2-trifluoroethylamino)acetonitrile —— C12H11F3N2O
    (2S)-2-(2,3-dihydro-1-benzofuran-5-yl)-2-(2,2,2-trifluoroethylamino)acetonitrile
    —— (3S)-6-hydroxy-3-(2,2,2-trifluoroethylamino)-2H-1-benzofuran-3-carbonitrile —— C11H9F3N2O2
    (3S)-6-hydroxy-3-(2,2,2-trifluoroethylamino)-2H-1-benzofuran-3-carbonitrile
    —— (3R)-6-hydroxy-3-(2,2,2-trifluoroethylamino)-2H-1-benzofuran-3-carbonitrile —— C11H9F3N2O2
    (3R)-6-hydroxy-3-(2,2,2-trifluoroethylamino)-2H-1-benzofuran-3-carbonitrile
    —— (2R)-2-(cycloheptylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile —— C17H22N2O
    (2R)-2-(cycloheptylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile
    —— (3R)-3-(cycloheptylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile —— C16H20N2O2
    (3R)-3-(cycloheptylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile
    —— 4-hydroxy-N-(2-hydroxyethyl)-3-[3-methylbut-2-enoyl(oxolan-2-ylmethyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C25H32N2O6
    4-hydroxy-N-(2-hydroxyethyl)-3-[3-methylbut-2-enoyl(oxolan-2-ylmethyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (2S)-2-(cyclohexylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile —— C16H20N2O
    (2S)-2-(cyclohexylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile
    —— (3R)-3-(cyclohexylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile —— C15H18N2O2
    (3R)-3-(cyclohexylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile
    —— (3S)-3-(cyclohexylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile —— C15H18N2O2
    (3S)-3-(cyclohexylamino)-6-hydroxy-2H-1-benzofuran-3-carbonitrile
    —— (2R)-2-(cyclohexylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile —— C16H20N2O
    (2R)-2-(cyclohexylamino)-2-(2,3-dihydro-1-benzofuran-5-yl)acetonitrile