摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (7-Methyl-5-oxo-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)methyl 3-phenylsulfanylpropanoate —— C16H15N3O3S2
    (7-Methyl-5-oxo-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)methyl 3-phenylsulfanylpropanoate
    —— N-[(2R)-4-phenylbutan-2-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide —— C19H25N3OS
    N-[(2R)-4-phenylbutan-2-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide
    —— 7-Methyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one —— C10H9N5OS3
    7-Methyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
    —— 2-(4,5,6-Trimethylpyrimidin-2-yl)sulfanyl-1-(1,2,5-trimethylpyrrol-3-yl)ethanone —— C16H21N3OS
    2-(4,5,6-Trimethylpyrimidin-2-yl)sulfanyl-1-(1,2,5-trimethylpyrrol-3-yl)ethanone
    —— 1-[2,5-Dimethyl-1-(1,3-thiazol-2-yl)pyrrol-3-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylethanone —— C18H20N4OS2
    1-[2,5-Dimethyl-1-(1,3-thiazol-2-yl)pyrrol-3-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylethanone
    —— N-[(1S)-1-(2,4-difluorophenyl)ethyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide —— C17H19F2N3OS
    N-[(1S)-1-(2,4-difluorophenyl)ethyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide
    —— (2R)-N-[(2S)-2-phenylpropyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C19H25N3OS
    (2R)-N-[(2S)-2-phenylpropyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— N-pentan-3-yl-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide —— C14H23N3OS
    N-pentan-3-yl-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide
    —— N-methyl-N-[(4-methylphenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide —— C18H23N3OS
    N-methyl-N-[(4-methylphenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylacetamide
    —— ethyl 2,4-dimethyl-5-[(2R)-2-[[5-(2-methylpropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate —— C18H26N4O3S2
    ethyl 2,4-dimethyl-5-[(2R)-2-[[5-(2-methylpropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate
    —— 2-(3,4-difluorophenyl)sulfanyl-N-[3-(N-methylanilino)propyl]acetamide —— C18H20F2N2OS
    2-(3,4-difluorophenyl)sulfanyl-N-[3-(N-methylanilino)propyl]acetamide
    —— (2S)-N-(1-cyanocyclohexyl)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C14H21N5OS2
    (2S)-N-(1-cyanocyclohexyl)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— 5-[(2-chloro-6-fluorophenyl)methylsulfanyl]-N-(2-methylpropyl)-1,3,4-thiadiazol-2-amine —— C13H15ClFN3S2
    5-[(2-chloro-6-fluorophenyl)methylsulfanyl]-N-(2-methylpropyl)-1,3,4-thiadiazol-2-amine
    —— 5-[[5-(5-bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl]methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine —— C11H10BrN5OS3
    5-[[5-(5-bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl]methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine
    —— N-[2-(4-chlorophenyl)sulfanylethyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C14H17ClN4OS3
    N-[2-(4-chlorophenyl)sulfanylethyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(4-ethylphenyl)methyl]-N-methylacetamide —— C16H22N4OS2
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(4-ethylphenyl)methyl]-N-methylacetamide
    —— 5-[(4-bromophenyl)methylsulfanyl]-N-(2-methylpropyl)-1,3,4-thiadiazol-2-amine —— C13H16BrN3S2
    5-[(4-bromophenyl)methylsulfanyl]-N-(2-methylpropyl)-1,3,4-thiadiazol-2-amine
    —— ethyl 2,4-dimethyl-5-[2-[[5-(2-methylpropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]-1H-pyrrole-3-carboxylate —— C17H24N4O3S2
    ethyl 2,4-dimethyl-5-[2-[[5-(2-methylpropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]-1H-pyrrole-3-carboxylate
    —— N-ethyl-5-[(3-thiophen-3-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine —— C11H11N5OS3
    N-ethyl-5-[(3-thiophen-3-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(furan-2-ylmethyl)-N-methylacetamide —— C12H16N4O2S2
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(furan-2-ylmethyl)-N-methylacetamide
    —— 2-[5-[2-[[5-(Ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]thiophen-2-yl]-1-morpholin-4-ylethanone —— C16H20N4O3S3
    2-[5-[2-[[5-(Ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]thiophen-2-yl]-1-morpholin-4-ylethanone
    —— N-cyclopropyl-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C13H20N4O3S3
    N-cyclopropyl-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— (2R)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide —— C15H19FN4OS2
    (2R)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide
    —— N-ethyl-5-[(2-thiophen-2-yl-1,3-oxazol-4-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine —— C12H12N4OS3
    N-ethyl-5-[(2-thiophen-2-yl-1,3-oxazol-4-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine
    —— N-[(2-bromophenyl)methyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methylacetamide —— C14H17BrN4OS2
    N-[(2-bromophenyl)methyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methylacetamide
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methyl-N-[(4-methylsulfanylphenyl)methyl]acetamide —— C15H20N4OS3
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methyl-N-[(4-methylsulfanylphenyl)methyl]acetamide
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-prop-2-enyl-N-(thiophen-2-ylmethyl)acetamide —— C14H18N4OS3
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-prop-2-enyl-N-(thiophen-2-ylmethyl)acetamide
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(2-methylphenyl)methyl]acetamide —— C14H18N4OS2
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(2-methylphenyl)methyl]acetamide
    —— N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C16H22N4OS2
    N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methyl-N-[(2-methylphenyl)methyl]acetamide —— C15H20N4OS2
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methyl-N-[(2-methylphenyl)methyl]acetamide
    —— 5-[(6-chloro-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine —— C14H16ClN3O2S2
    5-[(6-chloro-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine
    —— (2S)-N-benzyl-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methylpropanamide —— C15H20N4OS2
    (2S)-N-benzyl-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-methylpropanamide
    —— (2R)-N-cyclohexyl-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C13H22N4OS2
    (2R)-N-cyclohexyl-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— ethyl 5-[(2S)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C16H22N4O3S2
    ethyl 5-[(2S)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— 5-[(4-bromo-2-fluorophenyl)methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine —— C11H11BrFN3S2
    5-[(4-bromo-2-fluorophenyl)methylsulfanyl]-N-ethyl-1,3,4-thiadiazol-2-amine
    —— (2S)-4-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-2-(4-methyl-1,3-thiazol-2-yl)-3-oxobutanenitrile —— C12H13N5OS3
    (2S)-4-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-2-(4-methyl-1,3-thiazol-2-yl)-3-oxobutanenitrile
    —— 2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide —— C16H22N4OS2
    2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide
    —— (2S)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]cyclohexan-1-one —— C10H15N3OS2
    (2S)-2-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]cyclohexan-1-one
    —— (2R)-2-ethanimidoyl-3-oxo-4-[(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]butanenitrile —— C11H14N4OS3
    (2R)-2-ethanimidoyl-3-oxo-4-[(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]butanenitrile
    —— 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylacetamide —— C17H22N4O3S2
    2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylacetamide
    —— 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]acetamide —— C12H12ClF3N2O3S2
    2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]acetamide
    —— 4-methyl-3-(2-methylfuran-3-yl)-5-[(1S)-1-phenylethyl]sulfanyl-1,2,4-triazole —— C16H17N3OS
    4-methyl-3-(2-methylfuran-3-yl)-5-[(1S)-1-phenylethyl]sulfanyl-1,2,4-triazole
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C18H19ClN4O2S
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— N-[(4-fluorophenyl)methyl]-N-methyl-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C18H19FN4O2S
    N-[(4-fluorophenyl)methyl]-N-methyl-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-propylacetamide —— C17H24N4O4S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-propylacetamide
    —— N-[(4-chlorophenyl)methyl]-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylacetamide —— C14H17ClN4OS
    N-[(4-chlorophenyl)methyl]-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylacetamide
    —— N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C20H24N4O2S
    N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-[1-[(2R)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone —— C16H24N4O2S
    2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-[1-[(2R)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone
    —— Propan-2-yl 2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetate —— C13H17N3O3S
    Propan-2-yl 2-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetate
    —— 6-Amino-5-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]-3-methyl-1-propylpyrimidine-2,4-dione —— C14H20N6O3S
    6-Amino-5-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]-3-methyl-1-propylpyrimidine-2,4-dione