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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(4-methylphenyl)methyl]propanamide —— C16H20N4OS2
    (2S)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(4-methylphenyl)methyl]propanamide
    —— (2S)-N-cycloheptyl-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C15H24N4OS2
    (2S)-N-cycloheptyl-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— 4-(3-bromophenyl)sulfanyl-2-chloro-N'-hydroxybenzenecarboximidamide —— C13H10BrClN2OS
    4-(3-bromophenyl)sulfanyl-2-chloro-N'-hydroxybenzenecarboximidamide
    —— (1R)-1-(3-chloro-4-cyclohexylsulfanylphenyl)-N-ethylethanamine —— C16H24ClNS
    (1R)-1-(3-chloro-4-cyclohexylsulfanylphenyl)-N-ethylethanamine
    —— 3-chloro-4-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N'-hydroxybenzenecarboximidamide —— C11H12ClN5OS
    3-chloro-4-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N'-hydroxybenzenecarboximidamide
    —— (1S)-1-(3-chloro-4-cyclohexylsulfanylphenyl)-N-ethylethanamine —— C16H24ClNS
    (1S)-1-(3-chloro-4-cyclohexylsulfanylphenyl)-N-ethylethanamine
    —— (1S,2S)-1-(2-bromophenyl)sulfanyl-1-(5-bromothiophen-2-yl)butan-2-amine —— C14H15Br2NS2
    (1S,2S)-1-(2-bromophenyl)sulfanyl-1-(5-bromothiophen-2-yl)butan-2-amine
    —— (1R)-N-ethyl-1-[2-(2-methylphenyl)sulfanylphenyl]ethanamine —— C17H21NS
    (1R)-N-ethyl-1-[2-(2-methylphenyl)sulfanylphenyl]ethanamine
    —— (1R,2R,4S)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2R,4S)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid
    —— 2-(2-bromophenyl)sulfanyl-5-chloro-N'-hydroxybenzenecarboximidamide —— C13H10BrClN2OS
    2-(2-bromophenyl)sulfanyl-5-chloro-N'-hydroxybenzenecarboximidamide
    —— 2-(4-bromophenyl)sulfanyl-4-chloro-N'-hydroxybenzenecarboximidamide —— C13H10BrClN2OS
    2-(4-bromophenyl)sulfanyl-4-chloro-N'-hydroxybenzenecarboximidamide
    —— (1R,2R,4R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile —— C13H20N4S
    (1R,2R,4R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile
    —— (1S)-1-(4-butylsulfanyl-3-chlorophenyl)-N-ethylethanamine —— C14H22ClNS
    (1S)-1-(4-butylsulfanyl-3-chlorophenyl)-N-ethylethanamine
    —— (3R,4S)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C16H27NS
    (3R,4S)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (1S,2R,4S)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1S,2R,4S)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid
    —— (1R,2R)-1-(2-bromophenyl)sulfanyl-1-(5-bromothiophen-2-yl)butan-2-amine —— C14H15Br2NS2
    (1R,2R)-1-(2-bromophenyl)sulfanyl-1-(5-bromothiophen-2-yl)butan-2-amine
    —— (1R,2R,4R)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid —— C16H22O2S
    (1R,2R,4R)-4-ethyl-2-(3-methylphenyl)sulfanylcyclohexane-1-carboxylic acid
    —— (3S,4R)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C16H27NS
    (3S,4R)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (3R,4R)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C16H27NS
    (3R,4R)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— 2-(4-bromophenyl)sulfanyl-6-chloro-N'-hydroxybenzenecarboximidamide —— C13H10BrClN2OS
    2-(4-bromophenyl)sulfanyl-6-chloro-N'-hydroxybenzenecarboximidamide
    —— (1R)-1-[4-(4-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine —— C15H15BrClNS
    (1R)-1-[4-(4-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine
    —— (1S,2R,4R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile —— C13H20N4S
    (1S,2R,4R)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile
    —— (3S,4S)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine —— C16H27NS
    (3S,4S)-4-(3,4-dimethylphenyl)sulfanyl-5,5-dimethylhexan-3-amine
    —— (1R,2R,4S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile —— C13H20N4S
    (1R,2R,4S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-4-ethylcyclohexane-1-carbonitrile
    —— 5-bromo-2-[(2S)-2-ethylhexyl]sulfanylaniline —— C14H22BrNS
    5-bromo-2-[(2S)-2-ethylhexyl]sulfanylaniline
    —— (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine —— C11H16N4OS
    (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine
    —— (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine —— C11H16N4OS
    (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine
    —— (1S)-1-[4-(4-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine —— C15H15BrClNS
    (1S)-1-[4-(4-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine
    —— (1S)-1-[4-(2-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine —— C15H15BrClNS
    (1S)-1-[4-(2-bromophenyl)sulfanyl-3-chlorophenyl]-N-methylethanamine
    —— 3-chloro-4-[(2S)-2-ethylhexyl]sulfanylaniline —— C14H22ClNS
    3-chloro-4-[(2S)-2-ethylhexyl]sulfanylaniline
    —— (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine —— C11H16N4OS
    (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine
    —— 5-bromo-2-[(2R)-2-ethylhexyl]sulfanylaniline —— C14H22BrNS
    5-bromo-2-[(2R)-2-ethylhexyl]sulfanylaniline
    —— (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine —— C11H16N4OS
    (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(furan-2-yl)propan-2-amine
    —— (2S)-2-(4-bromophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C12H15BrN4S
    (2S)-2-(4-bromophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— (2R)-2-(4-bromophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C12H15BrN4S
    (2R)-2-(4-bromophenyl)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(4-methylphenyl)ethanamine —— C13H18N4S
    (2S)-2-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-2-(4-methylphenyl)ethanamine
    —— (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1S,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine
    —— 2-[(2S)-2-ethylhexyl]sulfanyl-5-methylaniline —— C15H25NS
    2-[(2S)-2-ethylhexyl]sulfanyl-5-methylaniline
    —— (1R,2R)-2-(2,5-dimethylphenyl)sulfanylcycloheptane-1-carboxylic acid —— C16H22O2S
    (1R,2R)-2-(2,5-dimethylphenyl)sulfanylcycloheptane-1-carboxylic acid
    —— (1S)-1-(3-chloro-4-thiophen-2-ylsulfanylphenyl)-N-ethylethanamine —— C14H16ClNS2
    (1S)-1-(3-chloro-4-thiophen-2-ylsulfanylphenyl)-N-ethylethanamine
    —— (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine
    —— 4-[(2R)-2-ethylhexyl]sulfanyl-3-fluoroaniline —— C14H22FNS
    4-[(2R)-2-ethylhexyl]sulfanyl-3-fluoroaniline
    —— 3-chloro-2-[(2S)-2-ethylhexyl]sulfanylaniline —— C14H22ClNS
    3-chloro-2-[(2S)-2-ethylhexyl]sulfanylaniline
    —— (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1R,2S)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine
    —— 4-[(2S)-2-ethylhexyl]sulfanyl-3-fluoroaniline —— C14H22FNS
    4-[(2S)-2-ethylhexyl]sulfanyl-3-fluoroaniline
    —— (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine —— C12H18N4S2
    (1R,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-methylthiophen-2-yl)propan-2-amine
    —— 3-chloro-2-[(2R)-2-ethylhexyl]sulfanylaniline —— C14H22ClNS
    3-chloro-2-[(2R)-2-ethylhexyl]sulfanylaniline
    —— (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-thiophen-3-ylbutan-2-amine —— C12H18N4S2
    (1S,2R)-1-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]-1-thiophen-3-ylbutan-2-amine
    —— (1R)-1-(3-chloro-4-thiophen-2-ylsulfanylphenyl)-N-ethylethanamine —— C14H16ClNS2
    (1R)-1-(3-chloro-4-thiophen-2-ylsulfanylphenyl)-N-ethylethanamine
    —— (1S)-1-[3-chloro-4-(2-methylpropylsulfanyl)phenyl]-N-ethylethanamine —— C14H22ClNS
    (1S)-1-[3-chloro-4-(2-methylpropylsulfanyl)phenyl]-N-ethylethanamine