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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-1-(2-chloro-6-pyridin-2-ylsulfanylphenyl)butan-2-amine —— C15H17ClN2S
    (2S)-1-(2-chloro-6-pyridin-2-ylsulfanylphenyl)butan-2-amine
    —— (3R)-3-hydroxy-6-(1-methylpyrazol-4-yl)sulfanyl-1,3-dihydroindol-2-one —— C12H11N3O2S
    (3R)-3-hydroxy-6-(1-methylpyrazol-4-yl)sulfanyl-1,3-dihydroindol-2-one
    —— (2R)-1-[3-fluoro-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]butan-2-amine —— C13H17FN4S
    (2R)-1-[3-fluoro-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]butan-2-amine
    —— (2R)-1-[5-fluoro-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine —— C12H15FN4S
    (2R)-1-[5-fluoro-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine
    —— 1-[1,3-dimethyl-5-[(1R,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]-N-methylmethanamine —— C14H25N3S
    1-[1,3-dimethyl-5-[(1R,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]-N-methylmethanamine
    —— (2R)-1-(3,5-difluoro-4-pyridin-2-ylsulfanylphenyl)propan-2-amine —— C14H14F2N2S
    (2R)-1-(3,5-difluoro-4-pyridin-2-ylsulfanylphenyl)propan-2-amine
    —— (2S)-1-(3,5-difluoro-4-pyridin-2-ylsulfanylphenyl)propan-2-amine —— C14H14F2N2S
    (2S)-1-(3,5-difluoro-4-pyridin-2-ylsulfanylphenyl)propan-2-amine
    —— (2S)-1-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine —— C12H16N4S
    (2S)-1-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine
    —— (2S)-1-[5-fluoro-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine —— C12H15FN4S
    (2S)-1-[5-fluoro-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]propan-2-amine
    —— (2R)-1-(2-chloro-6-pyridin-2-ylsulfanylphenyl)butan-2-amine —— C15H17ClN2S
    (2R)-1-(2-chloro-6-pyridin-2-ylsulfanylphenyl)butan-2-amine
    —— (2S)-1-(2-methyl-4-pyridin-2-ylsulfanylphenyl)propan-2-amine —— C15H18N2S
    (2S)-1-(2-methyl-4-pyridin-2-ylsulfanylphenyl)propan-2-amine
    —— (2S)-1-[3-fluoro-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]butan-2-amine —— C13H17FN4S
    (2S)-1-[3-fluoro-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]phenyl]butan-2-amine
    —— (2S)-1-[6-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]imidazo[2,1-b][1,3]thiazol-5-yl]propan-2-amine —— C11H14N6S2
    (2S)-1-[6-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]imidazo[2,1-b][1,3]thiazol-5-yl]propan-2-amine
    —— (3S)-3-hydroxy-6-(4-methylphenyl)sulfanyl-1,3-dihydroindol-2-one —— C15H13NO2S
    (3S)-3-hydroxy-6-(4-methylphenyl)sulfanyl-1,3-dihydroindol-2-one
    —— (2S)-1-[3-fluoro-4-(4-fluorophenyl)sulfanylphenyl]propan-2-amine —— C15H15F2NS
    (2S)-1-[3-fluoro-4-(4-fluorophenyl)sulfanylphenyl]propan-2-amine
    —— (2S)-1-(1,3-dimethyl-5-pyridin-2-ylsulfanylpyrazol-4-yl)butan-2-amine —— C14H20N4S
    (2S)-1-(1,3-dimethyl-5-pyridin-2-ylsulfanylpyrazol-4-yl)butan-2-amine
    —— 2-[2-[4-(3,4-Dimethylphenyl)sulfanylanilino]-2-oxoethoxy]benzamide —— C23H22N2O3S
    2-[2-[4-(3,4-Dimethylphenyl)sulfanylanilino]-2-oxoethoxy]benzamide
    —— (1R)-1-[5-fluoro-2-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[5-fluoro-2-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (2R)-1-(1,3-dimethyl-5-pyridin-2-ylsulfanylpyrazol-4-yl)butan-2-amine —— C14H20N4S
    (2R)-1-(1,3-dimethyl-5-pyridin-2-ylsulfanylpyrazol-4-yl)butan-2-amine
    —— (2S)-1-[4-(2,4-dimethylphenyl)sulfanylphenyl]propan-2-amine —— C17H21NS
    (2S)-1-[4-(2,4-dimethylphenyl)sulfanylphenyl]propan-2-amine
    —— (2R)-1-[4-(2,4-dimethylphenyl)sulfanylphenyl]propan-2-amine —— C17H21NS
    (2R)-1-[4-(2,4-dimethylphenyl)sulfanylphenyl]propan-2-amine
    —— (3S)-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]-1,1-dioxothiolane-3-carboxamide —— C19H21NO3S2
    (3S)-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]-1,1-dioxothiolane-3-carboxamide
    —— (1S)-1-[2-fluoro-6-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1S)-1-[2-fluoro-6-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1S)-1-[2-fluoro-6-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1S)-1-[2-fluoro-6-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (2S,3R,4S,7R,9R,10S,11S,12S,13S,14R,15S,18R,20R,21S,22R)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane —— C34H38O2S2
    (2S,3R,4S,7R,9R,10S,11S,12S,13S,14R,15S,18R,20R,21S,22R)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane
    —— (3S)-3-hydroxy-6-thiophen-2-ylsulfanyl-1,3-dihydroindol-2-one —— C12H9NO2S2
    (3S)-3-hydroxy-6-thiophen-2-ylsulfanyl-1,3-dihydroindol-2-one
    —— (1S)-1-[2-fluoro-6-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1S)-1-[2-fluoro-6-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1S)-1-[2-fluoro-6-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1S)-1-[2-fluoro-6-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1R)-1-[5-fluoro-2-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[5-fluoro-2-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1R)-1-[5-fluoro-2-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[5-fluoro-2-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1S,2S,3R,4S,7R,9R,10S,11R,13S,14R,15R,18R,20R,21S,22S)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane —— C34H38O2S2
    (1S,2S,3R,4S,7R,9R,10S,11R,13S,14R,15R,18R,20R,21S,22S)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane
    —— (2S,3R,4S,7S,9R,10S,11S,12S,13S,14R,15S,18R,20R,21S,22R)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane —— C34H38O2S2
    (2S,3R,4S,7S,9R,10S,11S,12S,13S,14R,15S,18R,20R,21S,22R)-10,21-dimethyl-9,20-bis(phenylsulfanyl)-8,19-dioxaoctacyclo[10.10.0.02,10.03,7.04,22.011,15.013,21.014,18]docosane
    —— (2S)-1-[4-(2,5-dichlorophenyl)sulfanylphenyl]propan-2-amine —— C15H15Cl2NS
    (2S)-1-[4-(2,5-dichlorophenyl)sulfanylphenyl]propan-2-amine
    —— (1S)-1-[3-chloro-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21ClOS
    (1S)-1-[3-chloro-4-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1R)-1-[2-fluoro-6-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[2-fluoro-6-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— [1,3-dimethyl-5-[(1R,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol —— C13H22N2OS
    [1,3-dimethyl-5-[(1R,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol
    —— (2R)-1-[4-(2,5-dichlorophenyl)sulfanylphenyl]propan-2-amine —— C15H15Cl2NS
    (2R)-1-[4-(2,5-dichlorophenyl)sulfanylphenyl]propan-2-amine
    —— (1R)-1-[2-fluoro-6-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[2-fluoro-6-[(1S,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— [1,3-dimethyl-5-[(1S,3S)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol —— C13H22N2OS
    [1,3-dimethyl-5-[(1S,3S)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol
    —— (1R)-1-[2-fluoro-6-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[2-fluoro-6-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (2S)-1-[3-fluoro-4-(2-fluorophenyl)sulfanylphenyl]propan-2-amine —— C15H15F2NS
    (2S)-1-[3-fluoro-4-(2-fluorophenyl)sulfanylphenyl]propan-2-amine
    —— (2S)-1-[4-bromo-2-(2-chlorophenyl)sulfanylphenyl]propan-2-amine —— C15H15BrClNS
    (2S)-1-[4-bromo-2-(2-chlorophenyl)sulfanylphenyl]propan-2-amine
    —— (1S)-1-[3-chloro-4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21ClOS
    (1S)-1-[3-chloro-4-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (1S)-1-[3-chloro-4-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21ClOS
    (1S)-1-[3-chloro-4-[(1S,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (2R)-1-[3-fluoro-4-(2-fluorophenyl)sulfanylphenyl]propan-2-amine —— C15H15F2NS
    (2R)-1-[3-fluoro-4-(2-fluorophenyl)sulfanylphenyl]propan-2-amine
    —— (2R)-1-[5-(2-chlorophenyl)sulfanyl-1,3-dimethylpyrazol-4-yl]propan-2-amine —— C14H18ClN3S
    (2R)-1-[5-(2-chlorophenyl)sulfanyl-1,3-dimethylpyrazol-4-yl]propan-2-amine
    —— (1R)-1-[2-fluoro-6-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21FOS
    (1R)-1-[2-fluoro-6-[(1R,3S)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— (2R)-1-[4-bromo-2-(2-chlorophenyl)sulfanylphenyl]propan-2-amine —— C15H15BrClNS
    (2R)-1-[4-bromo-2-(2-chlorophenyl)sulfanylphenyl]propan-2-amine
    —— (1S)-1-[3-chloro-4-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol —— C15H21ClOS
    (1S)-1-[3-chloro-4-[(1R,3R)-3-methylcyclohexyl]sulfanylphenyl]ethanol
    —— [1,3-dimethyl-5-[(1S,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol —— C13H22N2OS
    [1,3-dimethyl-5-[(1S,3R)-3-methylcyclohexyl]sulfanylpyrazol-4-yl]methanol