摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 5-bromo-4-oxo-2,3-dihydrothieno[3,4-b]thiopyran-7-carbaldehyde —— C8H5BrO2S2
    5-bromo-4-oxo-2,3-dihydrothieno[3,4-b]thiopyran-7-carbaldehyde
    —— N'-[(E)-(3-Bromophenyl)methylidene]-2-[(4-chlorophenyl)sulfanyl]acetohydrazide —— C15H12BrClN2OS
    N'-[(E)-(3-Bromophenyl)methylidene]-2-[(4-chlorophenyl)sulfanyl]acetohydrazide
    —— N-[(E)-benzylideneamino]-2-(4-chlorophenyl)sulfanylacetamide —— C15H13ClN2OS
    N-[(E)-benzylideneamino]-2-(4-chlorophenyl)sulfanylacetamide
    —— N-[(E)-(3-methylfuran-2-yl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C13H13N3O2S
    N-[(E)-(3-methylfuran-2-yl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— 5-[[2-(2-methylanilino)-1,3-thiazol-4-yl]methylsulfanyl]-N-[[(2R)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine —— C18H21N5OS3
    5-[[2-(2-methylanilino)-1,3-thiazol-4-yl]methylsulfanyl]-N-[[(2R)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine
    —— N-[(E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]pyridine-4-carboxamide —— C16H12N4O2S
    N-[(E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]pyridine-4-carboxamide
    —— 5-[[2-(2-methylanilino)-1,3-thiazol-4-yl]methylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine —— C18H21N5OS3
    5-[[2-(2-methylanilino)-1,3-thiazol-4-yl]methylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine
    —— 1-[(Z)-nonylideneamino]-3-(nonylideneamino)thiourea —— C19H38N4S
    1-[(Z)-nonylideneamino]-3-(nonylideneamino)thiourea
    —— 1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-5-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-1H-1,2,3-triazole-4-carbohydrazide —— C18H20N12O2S
    1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-5-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-1H-1,2,3-triazole-4-carbohydrazide
    —— 2-(4-chlorophenyl)sulfanyl-3-[(E)-hydroxyiminomethyl]pyrido[1,2-a]pyrimidin-4-one —— C15H10ClN3O2S
    2-(4-chlorophenyl)sulfanyl-3-[(E)-hydroxyiminomethyl]pyrido[1,2-a]pyrimidin-4-one
    —— 6-{[3-(Trifluoromethyl)phenyl]sulfanyl}imidazo[2,1-b][1,3]thiazole-5-carbaldehyde oxime —— C13H8F3N3OS2
    6-{[3-(Trifluoromethyl)phenyl]sulfanyl}imidazo[2,1-b][1,3]thiazole-5-carbaldehyde oxime
    —— 6-[(4-Methylphenyl)sulfanyl]nicotinaldehyde oxime —— C13H12N2OS
    6-[(4-Methylphenyl)sulfanyl]nicotinaldehyde oxime
    —— 1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde oxime —— C12H10F3N3OS
    1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde oxime
    —— N'-[(E)-(2-chloro-6-fluorophenyl)methylidene]-2-[(4,6-dimethyl-2-pyrimidinyl)thio]acetohydrazide —— C15H14ClFN4OS
    N'-[(E)-(2-chloro-6-fluorophenyl)methylidene]-2-[(4,6-dimethyl-2-pyrimidinyl)thio]acetohydrazide
    —— N-(benzoyloxy)-N-{[1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene}amine —— C19H14F3N3O2S
    N-(benzoyloxy)-N-{[1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene}amine
    —— 6-[(3-Chlorobenzyl)sulfanyl]imidazo[2,1-b][1,3]thiazole-5-carbaldehyde oxime —— C13H10ClN3OS2
    6-[(3-Chlorobenzyl)sulfanyl]imidazo[2,1-b][1,3]thiazole-5-carbaldehyde oxime
    —— (E)-{[1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylidene}amino 2-chloroacetate —— C14H11ClF3N3O2S
    (E)-{[1-methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylidene}amino 2-chloroacetate
    —— N'-{(E)-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]methylidene}-4-cyano-2-fluorobenzohydrazide —— C20H12FN5O2S
    N'-{(E)-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]methylidene}-4-cyano-2-fluorobenzohydrazide
    —— N'-{(E)-[5-(phenylsulfanyl)furan-2-yl]methylidene}acetohydrazide —— C13H12N2O2S
    N'-{(E)-[5-(phenylsulfanyl)furan-2-yl]methylidene}acetohydrazide
    —— N'-[(E)-{5-[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl}methylidene]furan-2-carbohydrazide —— C24H17N5O3S
    N'-[(E)-{5-[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]furan-2-yl}methylidene]furan-2-carbohydrazide
    —— (2E)-N-methyl-2-[5-nitro-2-(pyridin-2-ylsulfanyl)benzylidene]hydrazinecarbothioamide —— C14H13N5O2S2
    (2E)-N-methyl-2-[5-nitro-2-(pyridin-2-ylsulfanyl)benzylidene]hydrazinecarbothioamide
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(furan-2-yl)methanimine —— C15H14N4OS
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(furan-2-yl)methanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-chlorophenyl)methanimine —— C16H13ClN4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-chlorophenyl)methanimine
    —— N'-[(E)-(3-fluorophenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide —— C14H12FN3OS
    N'-[(E)-(3-fluorophenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide
    —— 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(E)-(4-ethylphenyl)methylidene]acetohydrazide —— C17H20N4OS
    2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(E)-(4-ethylphenyl)methylidene]acetohydrazide
    —— 3-(4-bromophenyl)-4-methylsulfanyl-1,2,5-thiadiazole —— C9H7BrN2S2
    3-(4-bromophenyl)-4-methylsulfanyl-1,2,5-thiadiazole
    —— 3-(3-bromophenyl)-4-methylsulfanyl-1,2,5-thiadiazole —— C9H7BrN2S2
    3-(3-bromophenyl)-4-methylsulfanyl-1,2,5-thiadiazole
    —— 5-[(Z)-2-(5-methylfuran-2-yl)ethenyl]-2-[[methyl-[(4-methylsulfanylphenyl)methyl]amino]methyl]-1H-1,2,4-triazole-3-thione —— C19H22N4OS2
    5-[(Z)-2-(5-methylfuran-2-yl)ethenyl]-2-[[methyl-[(4-methylsulfanylphenyl)methyl]amino]methyl]-1H-1,2,4-triazole-3-thione
    —— (2S)-2-phenyl-2-[4-[2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetyl]piperazin-1-yl]acetonitrile —— C20H19F3N4OS
    (2S)-2-phenyl-2-[4-[2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetyl]piperazin-1-yl]acetonitrile
    —— 4-[(E)-[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]-3-nitrophenyl]methylideneamino]-3-(naphthalen-1-ylmethyl)-1H-1,2,4-triazole-5-thione —— C23H18N8O2S2
    4-[(E)-[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]-3-nitrophenyl]methylideneamino]-3-(naphthalen-1-ylmethyl)-1H-1,2,4-triazole-5-thione
    —— (2S)-2-phenyl-2-[4-[2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]piperazin-1-yl]acetonitrile —— C22H21N5O2S
    (2S)-2-phenyl-2-[4-[2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]piperazin-1-yl]acetonitrile
    —— 1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-[(E)-(4-fluorophenyl)methylidene]-5-[(phenylsulfanyl)methyl]-1H-1,2,3-triazole-4-carbohydrazide —— C19H15FN8O2S
    1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-[(E)-(4-fluorophenyl)methylidene]-5-[(phenylsulfanyl)methyl]-1H-1,2,3-triazole-4-carbohydrazide
    —— 2-[2-[4-[(S)-cyano(phenyl)methyl]piperazin-1-yl]-2-oxoethyl]sulfanyl-4,6-dimethylpyridine-3-carbonitrile —— C22H23N5OS
    2-[2-[4-[(S)-cyano(phenyl)methyl]piperazin-1-yl]-2-oxoethyl]sulfanyl-4,6-dimethylpyridine-3-carbonitrile
    —— (2R)-2-phenyl-2-[4-[2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]piperazin-1-yl]acetonitrile —— C22H21N5O2S
    (2R)-2-phenyl-2-[4-[2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]piperazin-1-yl]acetonitrile
    —— (2R)-2-phenyl-2-[4-[2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetyl]piperazin-1-yl]acetonitrile —— C20H19F3N4OS
    (2R)-2-phenyl-2-[4-[2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetyl]piperazin-1-yl]acetonitrile
    —— 3-Methoxy-N'-[(E)-[5-(quinolin-8-ylsulfanyl)furan-2-YL]methylidene]benzohydrazide —— C22H17N3O3S
    3-Methoxy-N'-[(E)-[5-(quinolin-8-ylsulfanyl)furan-2-YL]methylidene]benzohydrazide
    —— 3-methoxy-N'-{(E)-[5-(pyridin-2-ylsulfanyl)furan-2-yl]methylidene}benzohydrazide —— C18H15N3O3S
    3-methoxy-N'-{(E)-[5-(pyridin-2-ylsulfanyl)furan-2-yl]methylidene}benzohydrazide
    —— 2-methyl-3-({(E)-[5-(quinolin-8-ylsulfanyl)furan-2-yl]methylidene}amino)quinazolin-4(3H)-one —— C23H16N4O2S
    2-methyl-3-({(E)-[5-(quinolin-8-ylsulfanyl)furan-2-yl]methylidene}amino)quinazolin-4(3H)-one
    —— 2-hydroxy-N'-[(E)-{4-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrophenyl}methylidene]benzohydrazide —— C18H15N5O4S
    2-hydroxy-N'-[(E)-{4-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrophenyl}methylidene]benzohydrazide
    —— (3S)-N-butyl-N-[2-(2-fluorophenyl)sulfanylethyl]-1,1-dioxothiolan-3-amine —— C16H24FNO2S2
    (3S)-N-butyl-N-[2-(2-fluorophenyl)sulfanylethyl]-1,1-dioxothiolan-3-amine
    —— (3R)-N-butyl-N-[2-(2-fluorophenyl)sulfanylethyl]-1,1-dioxothiolan-3-amine —— C16H24FNO2S2
    (3R)-N-butyl-N-[2-(2-fluorophenyl)sulfanylethyl]-1,1-dioxothiolan-3-amine
    —— 1-(2,6-Dimethylmorpholin-4-yl)-2-[(4-phenyl-1,3-thiazol-2-yl)sulfanyl]ethanone —— C17H20N2O2S2
    1-(2,6-Dimethylmorpholin-4-yl)-2-[(4-phenyl-1,3-thiazol-2-yl)sulfanyl]ethanone
    —— 2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(propylcarbamoyl)acetamide —— C17H27N5O2S
    2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(propylcarbamoyl)acetamide
    —— N-(1-cyano-1,2-dimethyl-propyl)-2-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]thio]acetamide —— C12H16F3N5OS
    N-(1-cyano-1,2-dimethyl-propyl)-2-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]thio]acetamide
    —— {(S)-2-Methyl-1-[5-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethylsulfanyl)-[1,3,4]oxadiazol-2-yl]-butyl}-carbamic acid tert-butyl ester —— C18H27N5O5S
    {(S)-2-Methyl-1-[5-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethylsulfanyl)-[1,3,4]oxadiazol-2-yl]-butyl}-carbamic acid tert-butyl ester
    —— 1-(2,6-Dimethylmorpholin-4-yl)-2-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]sulfanyl]ethanone —— C17H19FN2O2S2
    1-(2,6-Dimethylmorpholin-4-yl)-2-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]sulfanyl]ethanone
    —— (E)-3-amino-2-[2-[[5-(2-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]but-2-enenitrile —— C15H15N5OS2
    (E)-3-amino-2-[2-[[5-(2-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]but-2-enenitrile
    —— 1-[(7E)-3-(furan-2-yl)-7-(furan-2-ylmethylidene)-3a,4,5,6-tetrahydro-3H-indazol-2-yl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanone —— C20H19N5O3S
    1-[(7E)-3-(furan-2-yl)-7-(furan-2-ylmethylidene)-3a,4,5,6-tetrahydro-3H-indazol-2-yl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanone
    —— 2-benzylsulfanyl-5-[(2S)-pyrrolidin-1-ium-2-yl]-1,3,4-oxadiazole;chloride —— C13H16ClN3OS
    2-benzylsulfanyl-5-[(2S)-pyrrolidin-1-ium-2-yl]-1,3,4-oxadiazole;chloride
    —— N-carbamoyl-2-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]propanamide —— C8H10F3N5O2S
    N-carbamoyl-2-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]propanamide