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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-3-oxo-2-(4-phenyl-1,3-thiazol-2-yl)-4-(2H-triazol-4-ylsulfanyl)butanenitrile —— C15H11N5OS2
    (2R)-3-oxo-2-(4-phenyl-1,3-thiazol-2-yl)-4-(2H-triazol-4-ylsulfanyl)butanenitrile
    —— N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-3-phenylsulfanylpropanamide —— C17H25NOS
    N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-3-phenylsulfanylpropanamide
    —— N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-3-phenylsulfanylpropanamide —— C17H25NOS
    N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-3-phenylsulfanylpropanamide
    —— N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide —— C16H19NOS2
    N-[(1R)-1-(3,4-dimethylphenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide
    —— N-benzyl-N-[(1R)-1-cyclopropylethyl]-2-thiophen-2-ylsulfanylacetamide —— C18H21NOS2
    N-benzyl-N-[(1R)-1-cyclopropylethyl]-2-thiophen-2-ylsulfanylacetamide
    —— N-benzyl-N-[(1S)-1-cyclopropylethyl]-2-thiophen-2-ylsulfanylacetamide —— C18H21NOS2
    N-benzyl-N-[(1S)-1-cyclopropylethyl]-2-thiophen-2-ylsulfanylacetamide
    —— N-[(1S)-1-(3,4-dimethylphenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide —— C16H19NOS2
    N-[(1S)-1-(3,4-dimethylphenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide
    —— 2-[(E)-(4-methylsulfanylphenyl)methylideneamino]guanidine —— C9H12N4S
    2-[(E)-(4-methylsulfanylphenyl)methylideneamino]guanidine
    —— N-[(E)-benzylideneamino]-2-[(2,4-dimethyl-3,5-dioxo-1,2,4-triazin-6-yl)sulfanyl]acetamide —— C14H15N5O3S
    N-[(E)-benzylideneamino]-2-[(2,4-dimethyl-3,5-dioxo-1,2,4-triazin-6-yl)sulfanyl]acetamide
    —— 1-[4-(difluoromethylsulfanyl)phenyl]-3-[(E)-2-ethylbutylideneamino]thiourea —— C14H19F2N3S2
    1-[4-(difluoromethylsulfanyl)phenyl]-3-[(E)-2-ethylbutylideneamino]thiourea
    —— N-[(3-chlorophenyl)methyl]-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C16H15ClN6O2S
    N-[(3-chlorophenyl)methyl]-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C11H11BrN6OS
    2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— (2R)-N-ethyl-2-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide —— C13H16F3NOS
    (2R)-N-ethyl-2-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide
    —— N-[(1R)-1-(4-chlorophenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide —— C14H14ClNOS2
    N-[(1R)-1-(4-chlorophenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide
    —— (2S)-N-ethyl-2-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide —— C13H16F3NOS
    (2S)-N-ethyl-2-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide
    —— N-[(1S)-1-(4-chlorophenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide —— C14H14ClNOS2
    N-[(1S)-1-(4-chlorophenyl)ethyl]-2-thiophen-2-ylsulfanylacetamide
    —— N-[(2S)-1-hydroxypropan-2-yl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide —— C11H13F3N2O2S
    N-[(2S)-1-hydroxypropan-2-yl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide
    —— N-[(2R)-2-hydroxypropyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide —— C11H13F3N2O2S
    N-[(2R)-2-hydroxypropyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide —— C13H18N4O2S2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide —— C13H14ClN3O3S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide —— C18H20N4O3S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide
    —— N-[(2S)-2-hydroxypropyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide —— C11H13F3N2O2S
    N-[(2S)-2-hydroxypropyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide —— C18H20N4O3S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide —— C13H14ClN3O3S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide
    —— 1-(3,5-dimethylpyrazol-1-yl)-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]ethanone —— C14H15N7O2S
    1-(3,5-dimethylpyrazol-1-yl)-2-[[5-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]ethanone
    —— N-[(E)-benzylideneamino]-3-[(2,4,6-trimethylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine —— C19H21N5S
    N-[(E)-benzylideneamino]-3-[(2,4,6-trimethylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine
    —— N-[(3-chlorophenyl)methyl]-2-[[5-[(2Z)-2-(1-pyridin-2-ylethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C18H18ClN7OS
    N-[(3-chlorophenyl)methyl]-2-[[5-[(2Z)-2-(1-pyridin-2-ylethylidene)hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(2R)-1-hydroxypropan-2-yl]-5-nitrobenzamide —— C16H15FN2O4S
    2-(2-fluorophenyl)sulfanyl-N-[(2R)-1-hydroxypropan-2-yl]-5-nitrobenzamide
    —— 2-(2-fluorophenyl)sulfanyl-N-[(2S)-1-hydroxypropan-2-yl]-5-nitrobenzamide —— C16H15FN2O4S
    2-(2-fluorophenyl)sulfanyl-N-[(2S)-1-hydroxypropan-2-yl]-5-nitrobenzamide
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-[(2-methylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine —— C19H22N6S
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-[(2-methylphenyl)methylsulfanyl]-1H-1,2,4-triazol-5-amine
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine —— C14H18N6S
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-(pyridin-2-ylmethylsulfanyl)-1H-1,2,4-triazol-5-amine —— C17H19N7S
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-(pyridin-2-ylmethylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— N-tert-butyl-2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C19H29N7OS
    N-tert-butyl-2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine —— C16H24N6S
    N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C17H26N6S
    N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— N-[(E)-(3-bromophenyl)methylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C13H16BrN5S
    N-[(E)-(3-bromophenyl)methylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— 3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(2R)-1-hydroxypropan-2-yl]propanamide —— C13H21N3O2S
    3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(2R)-1-hydroxypropan-2-yl]propanamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(2-methylphenyl)methylideneamino]acetamide —— C16H15ClN2OS
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(2-methylphenyl)methylideneamino]acetamide
    —— 2-(4-chlorophenyl)sulfanyl-N-[(E)-(5-methylfuran-2-yl)methylideneamino]acetamide —— C14H13ClN2O2S
    2-(4-chlorophenyl)sulfanyl-N-[(E)-(5-methylfuran-2-yl)methylideneamino]acetamide
    —— 3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(2S)-1-hydroxypropan-2-yl]propanamide —— C13H21N3O2S
    3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(2S)-1-hydroxypropan-2-yl]propanamide
    —— (E)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-phenylmethanimine —— C19H19BrN4S
    (E)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-phenylmethanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-bromophenyl)methanimine —— C17H15BrN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-bromophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-4-ylmethanimine —— C16H15N5S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-4-ylmethanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine —— C16H13BrN4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine
    —— (E,Z)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine —— C19H18N4S
    (E,Z)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-chloro-6-fluorophenyl)methanimine —— C17H14ClFN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-chloro-6-fluorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine —— C18H18N4S2
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-bromophenyl)methanimine —— C17H15BrN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-bromophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-methylphenyl)methanimine —— C18H18N4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-methylphenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-ethylphenyl)methanimine —— C19H20N4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-ethylphenyl)methanimine