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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-4-[2-(3,4-dimethylphenyl)sulfanylethyl]-2-methylmorpholine —— C15H23NOS
    (2S)-4-[2-(3,4-dimethylphenyl)sulfanylethyl]-2-methylmorpholine
    —— (2R)-4-[2-(3,4-dimethylphenyl)sulfanylethyl]-2-methylmorpholine —— C15H23NOS
    (2R)-4-[2-(3,4-dimethylphenyl)sulfanylethyl]-2-methylmorpholine
    —— (2S)-N-methyl-2-methylsulfonyl-N-(2,2,2-trifluoroethyl)propanamide —— C7H12F3NO3S
    (2S)-N-methyl-2-methylsulfonyl-N-(2,2,2-trifluoroethyl)propanamide
    —— 3-(2-bromophenyl)sulfanyl-N-[(2R)-2-hydroxypropyl]propanamide —— C12H16BrNO2S
    3-(2-bromophenyl)sulfanyl-N-[(2R)-2-hydroxypropyl]propanamide
    —— 3-(2-bromophenyl)sulfanyl-N-[(2S)-2-hydroxypropyl]propanamide —— C12H16BrNO2S
    3-(2-bromophenyl)sulfanyl-N-[(2S)-2-hydroxypropyl]propanamide
    —— (2R)-N-methyl-2-methylsulfonyl-N-(2,2,2-trifluoroethyl)propanamide —— C7H12F3NO3S
    (2R)-N-methyl-2-methylsulfonyl-N-(2,2,2-trifluoroethyl)propanamide
    —— 3-(2-bromophenyl)sulfanyl-N-[(2S)-1-hydroxypropan-2-yl]propanamide —— C12H16BrNO2S
    3-(2-bromophenyl)sulfanyl-N-[(2S)-1-hydroxypropan-2-yl]propanamide
    —— N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-2-(2-methylpropylsulfonyl)acetamide —— C14H27NO3S
    N-cyclopropyl-N-[(2S)-3-methylbutan-2-yl]-2-(2-methylpropylsulfonyl)acetamide
    —— N-[(2R)-butan-2-yl]-N-butyl-3-cyclopentylsulfonylpropanamide —— C16H31NO3S
    N-[(2R)-butan-2-yl]-N-butyl-3-cyclopentylsulfonylpropanamide
    —— 3-(2-bromophenyl)sulfanyl-N-[(2R)-1-hydroxypropan-2-yl]propanamide —— C12H16BrNO2S
    3-(2-bromophenyl)sulfanyl-N-[(2R)-1-hydroxypropan-2-yl]propanamide
    —— N-[(2S)-butan-2-yl]-N-butyl-3-cyclopentylsulfonylpropanamide —— C16H31NO3S
    N-[(2S)-butan-2-yl]-N-butyl-3-cyclopentylsulfonylpropanamide
    —— N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-2-(2-methylpropylsulfonyl)acetamide —— C14H27NO3S
    N-cyclopropyl-N-[(2R)-3-methylbutan-2-yl]-2-(2-methylpropylsulfonyl)acetamide
    —— [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone —— C18H20N2O2S
    [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone
    —— [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone —— C18H20N2O2S
    [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone
    —— [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone —— C18H20N2O2S
    [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone
    —— [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone —— C18H20N2O2S
    [(3S)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S)-3-(1-methylpyrrol-2-yl)morpholin-4-yl]methanone
    —— 1-[(2R,4R)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea —— C17H24N2O2S
    1-[(2R,4R)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea
    —— 1-[(2S,4R)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea —— C17H24N2O2S
    1-[(2S,4R)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea
    —— 1-[(2S,4S)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea —— C17H24N2O2S
    1-[(2S,4S)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea
    —— 1-[(2R,4S)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea —— C17H24N2O2S
    1-[(2R,4S)-2-cyclopropyloxan-4-yl]-3-(2-phenylsulfanylethyl)urea
    —— 1-[(2S,4S)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea —— C18H26N2O2S
    1-[(2S,4S)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea
    —— 1-[(2R,4R)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea —— C18H26N2O2S
    1-[(2R,4R)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea
    —— 1-[(2R,4S)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea —— C18H26N2O2S
    1-[(2R,4S)-2-cyclopropyloxan-4-yl]-3-[(4-methyl-2-methylsulfanylphenyl)methyl]urea
    —— 3-[(2R)-hept-6-en-2-yl]sulfanyl-1H-1,2,4-triazol-5-amine —— C9H16N4S
    3-[(2R)-hept-6-en-2-yl]sulfanyl-1H-1,2,4-triazol-5-amine
    —— (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3O2S
    (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— 3-[(2S)-hept-6-en-2-yl]sulfanyl-1H-1,2,4-triazol-5-amine —— C9H16N4S
    3-[(2S)-hept-6-en-2-yl]sulfanyl-1H-1,2,4-triazol-5-amine
    —— (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3O2S
    (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3OS2
    (2S)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— 2-methoxy-N-[(E)-(5-quinolin-8-ylsulfanylfuran-2-yl)methylideneamino]acetamide —— C17H15N3O3S
    2-methoxy-N-[(E)-(5-quinolin-8-ylsulfanylfuran-2-yl)methylideneamino]acetamide
    —— (2R)-3-[(4-cyclopropyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1,1,1-trifluoropropan-2-ol —— C11H16F3N3OS
    (2R)-3-[(4-cyclopropyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1,1,1-trifluoropropan-2-ol
    —— (2R)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol —— C8H12F3N3OS
    (2R)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol
    —— (2S)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol —— C8H12F3N3OS
    (2S)-1,1,1-trifluoro-3-[(5-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-2-ol
    —— (5R)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one —— C13H13N3O2S
    (5R)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one
    —— (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol —— C11H12F3N3OS2
    (2R)-1,1,1-trifluoro-3-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-2-ol
    —— (5S)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one —— C13H13N3O2S
    (5S)-5-(1H-imidazol-2-ylsulfanylmethyl)-3-phenyl-1,3-oxazolidin-2-one
    —— 2,3,5,6-tetrafluoro-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-4-amine —— C13H9F4N3S
    2,3,5,6-tetrafluoro-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-4-amine
    —— (2R)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C10H18N4OS
    (2R)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C8H14N4OS
    (2S)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C10H18N4OS
    (2S)-N-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one —— C12H20N4OS
    (2S)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one
    —— (2R)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C8H14N4OS
    (2R)-N,N-dimethyl-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2R)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one —— C12H20N4OS
    (2R)-1-(azepan-1-yl)-2-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-one
    —— (2R)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile —— C14H13N3OS2
    (2R)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile
    —— (2S)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile —— C14H13N3OS2
    (2S)-3-(2-ethylsulfanylpyridin-4-yl)-2-(4-methyl-1,3-thiazol-2-yl)-3-oxopropanenitrile
    —— (2R)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2R)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— (2S)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2S)-N-[(1S)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— (2R)-N-[(1R)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    (2R)-N-[(1R)-1-cyclohexylethyl]-2-methyl-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1R,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1R,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1S,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1S,2R)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine
    —— N-methyl-N-[[(1S,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine —— C13H27NO2S
    N-methyl-N-[[(1S,2S)-2-methylcyclohexyl]methyl]-3-methylsulfonylpropan-1-amine