黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 3-羟基-4-[(2E)-3-(4-羟基苯基)-2-丙烯酰基]苯基beta-D-吡喃葡萄糖苷 | neoisoliquiritigenin | 59122-93-9 | C21H22O9 |
|
| 3-羟基-4'-甲基黄酮 | 3-Hydroxy-4'-methylflavone | 19275-68-4 | C16H12O3 |
|
| 3-羟基-3’-甲氧基黄酮 | 3-hydroxy-2-(3-methoxyphenyl)-4H-chromen-4-one | 76666-32-5 | C16H12O4 |
|
| 3-羟基-3-甲基-5-氧代-5-[[(2R,3S,4S,5R,6S)-3,4,5-三羟基-6-[(2S)-5-羟基-2-(4-甲氧基苯基)-6,8-二甲基-4-氧代色满-7-基]氧基四氢吡喃-2-基]甲氧基]戊酸 | matteuorienate A | 161161-68-8 | C30H36O14 |
|
| 3-羟基-3,4,5,7-四甲氧基黄酮 | 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-4-chromenone | 1244-78-6 | C19H18O7 |
|
| 3-羟基-2-苯基-4H-苯并[h]苯并吡喃-4-酮 | 3-hydroxy-2-phenyl-4H-benzo[h]chromen-4-one | 22812-50-6 | C19H12O3 |
|
| 3-羟基-2-甲氧基黄烷酮 | 3-hydroxy-2-methoxyflavanone | 1050685-79-4 | C16H14O4 |
|
| 3-羟基-2-(4-羟基苯基)-6,7-二甲氧基苯并吡喃-4-酮 | Hortensin | 123442-39-7 | C17H14O6 |
|
| 3-羟基-2,3-二甲氧基-2-苯基色烯-4-酮 | 3-hydroxy-2,3-dimethoxyflavan-4-one | 1603-46-9 | C17H16O5 |
|
| 3-羟基-2,3,7-三甲氧基-2-苯基色烯-4-酮 | 3-hydroxy-2,3,7-trimethoxy-2-phenyl-chroman-4-one | 2047-54-3 | C18H18O6 |
|
| 3-羟基-2,3,4'-三甲氧基黄烷-4-酮 | 3-hydroxy-2,3,4'-trimethoxyflavan-4-one | 1808-05-5 | C18H18O6 |
|
| 3-羟基-2'-甲氧基黄酮 | 3-hydroxy-2-(2-methoxy-phenyl)-chromen-4-one | 29219-03-2 | C16H12O4 |
|
| 3-碘-7-甲氧基-2-苯基-色烯-4-酮 | 3-iodo-7-methoxy-2-phenylchromone | 153446-72-1 | C16H11IO3 |
|
| 3-碘-2-苯基-色烯-4-酮 | 3-iodo-2-phenyl-4H-chromen-4-one | 98153-12-9 | C15H9IO2 |
|
| 3-硝基-2-苯基色烯-4-酮 | 3-Nitroflavone | 10524-88-6 | C15H9NO4 |
|
| 3-甲氧基黄酮 | 3-Methoxy-flavon | 7245-02-5 | C16H12O3 |
|
| 3-甲氧基-吡咯烷盐酸 | Sorocein A | 137460-77-6 | C39H34O8 |
|
| 3-甲氧基-8-甲基-2-苯基色烯-4-酮 | 3-methoxy-8-methyl-2-phenylchromen-4-one | 87165-68-2 | C17H14O3 |
|
| 3-甲氧基-2-苯基-2H-色烯 | 3-Methoxy-Δ<sup>3</sup>-flaven | 63154-82-5 | C16H14O2 |
|
| 3-甲基黄酮-8-羧酸乙酯 | Ethyl 3-methylflavone-8-carboxylate | 35888-94-9 | C19H16O4 |
|
| 3-甲基黄酮-8-羧酸 | 3-methylflavone-8-carboxylic acid | 3468-01-7 | C17H12O4 |
|
| 3-甲基-7-甲氧基-8-氯甲基-4'-氯黄酮 | 3-Methyl-7-methoxy-8-chloromethyl-4'-chloroflavone | 86073-67-8 | C18H14Cl2O3 |
|
| 3-甲基-7-甲氧基-8-氯甲基-4'-氟黄酮 | 3-Methyl-7-methoxy-8-chloromethyl-4'-fluoroflavone | 86073-68-9 | C18H14ClFO3 |
|
| 3-甲基-7-甲氧基-4'-氟黄酮 | 3-Methyl-7-methoxy-4'-fluoroflavone | 86073-66-7 | C17H13FO3 |
|
| 3-甲基-4-氧代-2-苯基-N-(2-(1-哌啶基)乙基)-4H-1-苯并吡喃-8-甲酰胺盐酸盐 | hydron;3-methyl-4-oxo-2-phenyl-N-(2-piperidin-1-ylethyl)chromene-8-carboxamide;chloride | —— | C24H27ClN2O3 |
|
| 3-甲基-2-苯基-8-(1-丙烯基)-4-苯并吡喃酮 | 3-methyl-2-phenyl-8-(1-propenyl)-4H-1-benzopyran-4-one | 3468-00-6 | C19H16O2 |
|
| 3-甲基-2-苯基-4H-1-苯并吡喃-4-酮 | 3-methyl-2-phenyl-4H-chromen-4-one | 71972-66-2 | C16H12O2 |
|
| 3-烯丙基-2-(4-甲氧基苯基)-4H-色烯-4-酮 | 3-allyl-2-(4-methoxyphenyl)-4H-chromen-4-one | 1307886-71-0 | C19H16O3 |
|
| 3-溴黄酮 | 3-bromo-2-phenyl-chromen-4-one | 1025-86-1 | C15H9BrO2 |
|
| 3-溴-7-甲氧基-2-(4-甲氧基苯基)-2H-色烯 | 3-bromo-4',7-dimethoxyflav-3-ene | 89840-34-6 | C17H15BrO3 |
|
| 3-溴-6-硝基-2-苯基-色烯-4-酮 | 3-bromo-6-nitro-2-phenyl-chromen-4-one | 100914-07-6 | C15H8BrNO4 |
|
| 3-溴-6-甲基黄酮 | 3-bromo-6-methylflavone | 73910-82-4 | C16H11BrO2 |
|
| 3-溴-2-苯基-2,3-二氢色烯-4-酮 | 3-bromoflavanone | 75630-64-7 | C15H11BrO2 |
|
| 3-溴-2-甲氧基黄烷-4-酮 | 3-bromo-2-methoxyflavan-4-one | 88187-02-4 | C16H13BrO3 |
|
| 3-溴-2-(4-甲氧基苯基)-4H-色烯 | 3-bromo-4'-methoxyflav-2-ene | 88186-93-0 | C16H13BrO2 |
|
| 3-氯-6-甲基-2-苯基色烯-4-酮 | 3-chloro-6-methylflavone | 13178-99-9 | C16H11ClO2 |
|
| 3-氯-2-苯基-2,3-二氢色烯-4-酮 | 3-chloroflavanone | 70460-47-8 | C15H11ClO2 |
|
| 3-氮杂二环[3.1.1]庚烷,3-甲基-1-(4-甲基苯基)- | [(2R,3S,4S,5R,6S)-6-[5-[5-[(2S,3R,4S,5S,6R)-6-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-7-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromenylium-2-yl]-2,3-dihydroxyphenoxy]-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate;chloride | 84331-34-0 | C51H53ClO28 |
|
| 3-氨基-2-苯基色烯-4-酮 | 3-aminoflavone | 6928-56-9 | C15H11NO2 |
|
| 3-氨基-2-苯基-2,3-二氢色烯-4-酮 | (4-oxo-2-phenyl-2,3-dihydrochromen-3-yl)azanium;chloride | —— | C15H13NO2*ClH |
|
| 3-氨基-2-(3-氨基-4-甲氧苯基)-4H-色烯-4-酮 | 3,3'-Diamino-4'-methoxyflavone | 187585-11-1 | C16H14N2O3 |
|
| 3-吗啉-4-基-2-苯基色烯-4-酮 | 3-morpholinoflavone | 81281-86-9 | C19H17NO3 |
|
| 3-乙酸山姜酮 | pinobanksin 3-acetoxy-7-methyl ether | 139906-49-3 | C18H16O6 |
|
| 3-乙酰氧基-7-甲氧基黄酮 | 3-acetyl-3,5,4'-trihydroxy-7-methoxyflavone | 21829-43-6 | C18H14O5 |
|
| 3-乙酰氧基-4',7-二甲氧基黄酮 | 3-acetoxy-4',7-dimethoxyflavone | 77184-88-4 | C19H16O6 |
|
| 3-乙基-7-羟基-8-吗啉-4-基甲基-2-苯基-色烯-4-酮 | 7-Hydroxy-3-ethyl-8-morpholinomethyl-2-phenyl-chromon | 102756-77-4 | C22H23NO4 |
|
| 3-乙基-7-羟基-2-苯基-色烯-4-酮 | 3-ethyl-7-hydroxy-2-phenyl-chromen-4-one | 101451-58-5 | C17H14O3 |
|
| 3-乙基-2-苯基-4H-苯并吡喃-4-酮 | 3-ethyl-2-phenyl-4H-chromen-4-one | 107152-93-2 | C17H14O2 |
|
| 3-{[(4-氯苯基)氨基]甲基}-5-(3,4,5-三甲氧苯基)-1,3,4-噁二唑-2(3H)-酮 | 6-chloro-2-(4-chlorophenyl)-2H-chromene | 73110-92-6 | C15H10Cl2O |
|
| 3-[[6-O-(6-脱氧-α-L-吡喃鼠李糖基)-β-D-吡喃葡萄糖基]氧代]-2-(3,4-二羟基苯基)-5,7-二羟基-6-(羟甲基)-4H-苯并吡喃-4-酮 | 3-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(hydroxymethyl)-4H-benzopyran-4-one | 153-17-3 | C28H32O17 |
|
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