黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 5,3'-二羟基-6,7,4',5'-四甲氧基黄酮 | 5-Hydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-6,7-dimethoxychromen-4-one | 111537-41-8 | C19H18O8 |
|
| 5,3'-二羟基-3,7,4'-三甲氧基黄酮 | ayanin | 572-32-7 | C18H16O7 |
|
| 5,3',4'-三羟基-3,7-二甲氧基黄酮 | 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxychromen-4-one | 2068-02-2 | C17H14O7 |
|
| 5,3',4'-三羟基-3,6,7,8-四甲氧基黄酮 | 5,3',4'-Trihydroxy-3,6,7,8-tetramethoxyflavone | 81943-52-4 | C19H18O9 |
|
| 5,2-二羟基黄酮 | 5,2’-dihydroxyflavone | 6674-39-1 | C15H10O4 |
|
| 5,2'-二甲氧基-6,7-亚甲二氧基黄烷酮 | Betagarin | 60132-69-6 | C18H16O6 |
|
| 5,2',6'-三羟基-6,7,8-三甲氧基黄酮 | 5,2',6'-trihydroxy-6,7,8-trimethoxyflavone | 98187-98-5 | C18H16O8 |
|
| 5(2H)-异噻唑酮,2-([1,4'-联哌啶]-1'-基羰基)-3-甲基-4-(1-甲基乙基)- | 2-(4-Chloro-phenyl)-3-nitro-chromen-4-one | 143468-16-0 | C15H8ClNO4 |
|
| 5'-甲氧基川陈皮素 | 2-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-benzopyran-4-one | 6965-36-2 | C22H24O9 |
|
| 5'-异戊烯基高圣草酚 | Sbmet | 114340-00-0 | C21H22O6 |
|
| 4’-羟基-6-甲基黄酮 | 2-(4-hydroxyphenyl)-6-methyl-4H-chromen-4-one | 288401-04-7 | C16H12O3 |
|
| 4’,5,6,7-四甲氧基黄酮 | 5,6,7,4'-tetramethoxyflavone | 1168-42-9 | C19H18O6 |
|
| 4H-呋喃并[2,3-h]-1-苯并吡喃-4-酮,2-(1,3-苯并二噁唑-5-基)- | pongaglabrone | 1236-78-8 | C18H10O5 |
|
| 4H-1-苯并吡喃-4-酮,8-羟基-5,6,7-三甲氧基-2-(3,4,5-三甲氧苯基)- | 8-hydroxy-5,6,7,3',4',5'-hexamethoxyflavone | 135010-80-9 | C21H22O9 |
|
| 4H-1-苯并吡喃-4-酮,8-溴-7-丁氧基-6-硝基-2-(3,4,5-三甲氧苯基)- | 8-bromo-7-butoxy-6-nitro-2-(3,4,5-trimethoxyphenyl)chromen-4-one | 135878-83-0 | C22H22BrNO8 |
|
| 4H-1-苯并吡喃-4-酮,8-[[2-(二乙胺基)乙氧基]甲基]-2-苯基-,乙二酸酯(1:1) | 8-<2-(N,N-diethylamino)ethoxy>methyl-2-phenyl-4H-1-benzopyran-4-one oxalate | 101002-51-1 | C2H2O4*C22H25NO3 |
|
| 4H-1-苯并吡喃-4-酮,7-(b-D-吡喃葡萄糖氧基)-2,3-二氢-5-羟基-6-(甲氧基甲基)-2-(4-甲氧苯基)-8-甲基-,(2S)- | (2)-7-β-glucosyloxy-5-hydroxy-4'-methoxy-6-methoxymethyl-8-methylflavanone | 101395-04-4 | C25H30O11 |
|
| 4H-1-苯并吡喃-4-酮,6-氟-2-(4-甲氧苯基)- | 6-Fluor-4'-methoxy-flavon | 1226-56-8 | C16H11FO3 |
|
| 4H-1-苯并吡喃-4-酮,6-[[6-[4-(4-氯苯基)-1-哌嗪基]己基]氧代]-2-苯基- | 6-[6-(4-(4-Chlorophenyl)piperazinyl)hexoxy]-2-phenyl-4H-1-benzopyran-4-one | 139652-53-2 | C31H33ClN2O3 |
|
| 4H-1-苯并吡喃-4-酮,6-[4-(二甲氨基)丁氧基]-2-苯基- | 6-(4-Dimethylamino-butoxy)-2-phenyl-chromen-4-one | 139652-68-9 | C21H23NO3 |
|
| 4H-1-苯并吡喃-4-酮,6-[(1S,5S,6R)-6-[2,4-二羟基-3-(3-甲基-2-丁烯-1-基)苯甲酰]-5-(2,4-二羟基苯基)-3-甲基-2-环己烯-1-基]-2-(2,4-二羟基苯基)-5,7-二羟基- | artonin I | 144923-70-6 | C40H36O11 |
|
| 4H-1-苯并吡喃-4-酮,5-羟基-6,7-二甲氧基-2-(2,3,4,5-四甲氧苯基)- | Agecorynin F | 144525-23-5 | C21H22O9 |
|
| 4H-1-苯并吡喃-4-酮,5-羟基-2-(3-羟基-4-甲氧苯基)-3,6,7,8-四甲氧基- | 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone | 102673-80-3 | C20H20O9 |
|
| 4H-1-苯并吡喃-4-酮,5-羟基-2-(3-羟基-2,4,5-三甲氧苯基)-6,7-二甲氧基- | psiadiarabin | 111950-81-3 | C20H20O9 |
|
| 4H-1-苯并吡喃-4-酮,5-氨基-2-(4-氨基苯基)-(9CI) | 5,4'-Diaminoflavone | 130599-46-1 | C15H12N2O2 |
|
| 4H-1-苯并吡喃-4-酮,5-[[6-(4-羟基-1-哌啶基)己基]氧代]-2-苯基- | 5-[6-(4-hydroxypiperidinyl)hexoxy]-2-phenyl-4H-1-benzopyran-4-one | 140438-92-2 | C26H31NO4 |
|
| 4H-1-苯并吡喃-4-酮,5-[3-(4-羟基-1-哌啶基)丙氧基]-2-苯基- | 5-[3-(4-hydroxypiperidinyl)propoxy]-2-phenyl-4H-1-benzopyran-4-one | 140438-91-1 | C23H25NO4 |
|
| 4H-1-苯并吡喃-4-酮,5,7-二羟基-3-[[6-O-[[4-(1-羟基-1-甲基乙基)-1-环己烯-1-基]羰基]-b-D-吡喃半乳糖基]氧代]-2-(4-羟基苯基)-(9CI) | resinoside A | 144027-78-1 | C31H34O13 |
|
| 4H-1-苯并吡喃-4-酮,5,7-二羟基-2-(5-羟基-2,4-二甲氧苯基)-3,6,8-三甲氧基- | 5,7,5'-trihydroxy-3,6,8,2',4'-pentamethoxyflavone | 100363-95-9 | C20H20O10 |
|
| 4H-1-苯并吡喃-4-酮,5,7-二羟基-2,8-二苯基- | 8-C-phenylchrysin | 190973-06-9 | C21H14O4 |
|
| 4H-1-苯并吡喃-4-酮,3-羟基-2-(2-羟基-4,5-二甲氧苯基)-5,6,7-三甲氧基- | 2',3-dihydroxy-4',5,5',6,7-pentamethoxyflavone | 105827-17-6 | C20H20O9 |
|
| 4H-1-苯并吡喃-4-酮,2-[4-(溴甲基)苯基]- | 4'-bromomethyl flavone | 152862-84-5 | C16H11BrO2 |
|
| 4H-1-苯并吡喃-4-酮,2-[4-(二甲氨基)苯基]-3-甲氧基- | 2-[4-(Dimethylamino)phenyl]-3-methoxy-4H-1-benzopyran-4-one | 153499-29-7 | C18H17NO3 |
|
| 4H-1-苯并吡喃-4-酮,2-[3-(b-D-吡喃葡萄糖氧基)-2-羟基苯基]-5-羟基-7,8-二甲氧基- | andrographidine B | 113963-38-5 | C23H24O12 |
|
| 4H-1-苯并吡喃-4-酮,2-[3,4-二(苯基甲氧基)苯基]-3,5-二甲氧基-7-(苯基甲氧基)- | 2-(3,4-bis(benzyloxy)phenyl)-7-(benzyloxy)-3,5-dimethoxy-4H-chromen-4-one | 1486-56-2 | C38H32O7 |
|
| 4H-1-苯并吡喃-4-酮,2-(4-羟基苯基)-3,7-二甲氧基- | 2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-chromen-4-one | 111391-83-4 | C17H14O5 |
|
| 4H-1-苯并吡喃-4-酮,2-(4-羟基-3-甲氧苯基)-5,7-二甲氧基- | 2-(4-hydroxy-3-methoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one | 1239-68-5 | C18H16O6 |
|
| 4H-1-苯并吡喃-4-酮,2-(4-羟基-2,3,6-三甲氧苯基)-5,6,7-三甲氧基- | 4'-hydroxy-2',3',5,6,6',7-hexamethoxyflavone | 105827-26-7 | C21H22O9 |
|
| 4H-1-苯并吡喃-4-酮,2-(4-氨基苯基)-7-羟基-(9CI) | 4'-amino-7-hydroxyflavone | 132018-31-6 | C15H11NO3 |
|
| 4H-1-苯并吡喃-4-酮,2-(4-氟苯基)-2,3-二氢- | 2-(4-fluorophenyl)-2,3-dihydro-4H-chromen-4-one | 1840-02-4 | C15H11FO2 |
|
| 4H-1-苯并吡喃-4-酮,2-(3-氟苯基)-6-[[6-(4-羟基-1-哌啶基)己基]氧代]- | 2-(3-fluorophenyl)-6-[6-(4-hydroxypiperidinyl)hexoxy]-4H-1-benzopyran-4-one | 139652-25-8 | C26H30FNO4 |
|
| 4H-1-苯并吡喃-4-酮,2-(3,4-二羟基苯基)-3,5-二羟基-7-(苯基甲氧基)- | 7-O-benzylquercetin | 13459-12-6 | C22H16O7 |
|
| 4H-1-苯并吡喃-4-酮,2-(3,4-二甲氧苯基)-5-羟基-3,7,8-三甲氧基- | 2-(3,4-dimethoxy-phenyl)-5-hydroxy-3,7,8-trimethoxy-chromen-4-one | 14965-12-9 | C20H20O8 |
|
| 4H-1-苯并吡喃-4-酮,2-(3,4-二甲氧苯基)-5,7-二甲氧基-3-甲基- | 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3-methyl-4H-1-benzopyran-4-one | 18651-46-2 | C20H20O6 |
|
| 4H-1-苯并吡喃-4-酮,2-(2-氯苯基)-6-羟基- | 2'-chloro-6-hydroxyflavone | 140439-32-3 | C15H9ClO3 |
|
| 4H-1-苯并吡喃-4-酮,2-(2,6-二羟基-3-甲氧苯基)-5,7-二羟基-8-甲氧基- | 3',8-dimethoxy-2',5,6',7-tetrahydroxyflavone | 101909-88-0 | C17H14O8 |
|
| 4H-1-苯并吡喃-4-酮,2-(2,4-二羟基苯基)-7-羟基- | 7,2',4'-trihydroxyflavone | 1032-80-0 | C15H10O5 |
|
| 4H-1-苯并吡喃-4-酮,2-(2,4-二羟基苯基)- | 2’,4’-dihydroxyflavone | 170310-00-6 | C15H10O4 |
|
| 4H-1-苯并吡喃-4-酮,2-(1,3-苯并二噁唑-5-基)-5,6,7-三甲氧基- | 5,6,7-Trimethoxy-3',4'-methylenedioxyflavone | 106636-80-0 | C19H16O7 |
|
| 4H-1-苯并吡喃-4-酮,2,3-二氢-6-碘-2-苯基- | 6-Jod-flavanon | 1218-83-3 | C15H11IO2 |
|
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