黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| —— | 5-hydroxy-3,7-dimethoxy-6-(diphenylmethyl)flavone | 98498-31-8 | C30H24O5 |
|
| —— | 3-acetoxy-6,8-dichloro-2-phenyl-chromen-4-one | 101883-69-6 | C17H10Cl2O4 |
|
| —— | (2R,3S)-5,6,7,3',4'-pentahydroxy-8-(2,2,2-trifluoroacetyl)flavan-3-ol | 917567-26-1 | C17H13F3O8 |
|
| —— | (2R,3R)-cis-3',4'-dimethoxy-6-methylflavan-3-ol | 1196870-30-0 | C18H20O4 |
|
| —— | Toluene-4-sulfonic acid 7-benzyloxy-2-(4-benzyloxy-3-methoxy-phenyl)-5,6,8-trimethoxy-4-oxo-4H-chromen-3-yl ester | 176662-19-4 | C40H36O11S |
|
| —— | (R)-4-oxo-2-phenylchroman-7-yl acetate | 1438761-23-9 | C17H14O4 |
|
| —— | 3,7,4'-Triethoxy-3,8-dimethoxy-flavon | 14965-17-4 | C23H26O7 |
|
| —— | 3,3-bis(4-methoxyphenyl)-5-methoxy-11-phenyl-13,13-dimethyl-3H,13H-indeno[2',1':3,4]naphtho[1,2-b]pyran | 1380855-55-9 | C43H36O4 |
|
| —— | 7-(N-Morpholinoaethoxy)flavon | 10400-03-0 | C21H21NO4 |
|
| —— | 4-oxo-2-phenyl-4H-chromene-3,6-diyl bis(3-methylbenzoate) | 1244966-64-0 | C31H22O6 |
|
| —— | 2',5'-diisopropyloxy-5,7,8-trimethoxyflavone | 101909-67-5 | C24H28O7 |
|
| —— | 2-(3,4-Dimethoxy-phenyl)-3-hydroxy-5,7-dimethoxy-6-methoxymethoxy-chromen-4-one | 170234-69-2 | C21H22O9 |
|
| —— | 2,8-di-(o-chlorophenyl)-3,7-dihydroxy-4,6-dioxo-4H,6H-benzo<1,2-b:5,4-b'>dipyran | 115540-53-9 | C24H12Cl2O6 |
|
| —— | 5-Amino-2-[4-(2-dimethylaminoethyl)oxy]phenyl-4H-benzopyran-4-one | 129974-44-3 | C19H20N2O3 |
|
| —— | 1-[5,5-Bis(4-methoxyphenyl)-1',1',5',5'-tetramethyl-10-methylsulfanylspiro[6-oxapentacyclo[12.7.0.02,7.08,13.015,20]henicosa-1(14),2(7),3,8,10,12,15,17,19-nonaene-21,3'-cyclohexane]-11-yl]piperidine | 1263318-19-9 | C49H53NO3S |
|
| —— | 5-Acetoxy-7-methoxy-6,8-dimethylflavanon | 51621-53-5 | C20H20O5 |
|
| —— | 8-chloro-5-hydroxy-7-methoxyflavone | 75643-00-4 | C16H11ClO4 |
|
| —— | 3',4'-Dimethoxy-6-methyl-flavan | 20052-38-4 | C18H20O3 |
|
| —— | 4-(2-Methoxy-phenyl)-flavan-4-ol | 96457-17-9 | C22H20O3 |
|
| —— | 4'-Benzyloxy-3',5,6,7-tetramethoxy-flavanone | 23494-60-2 | C26H26O7 |
|
| —— | 2-(3,5-dimethoxy-phenyl)-4-oxo-4<i>H</i>-chromene-6-carboxylic acid | 66848-97-3 | C18H14O6 |
|
| —— | acetic acid 4,5-diacetoxy-6-acetoxymethyl-2-[2-(3,4-dihydroxy-phenyl)-4-oxo-4H-chromen-3-yloxy]-tetrahydro-pyran-3-yl ester | 918309-46-3 | C29H28O14 |
|
| —— | Isopropyliden-<7,3',4'-trimethoxy-flavan-3,4-diol> | 88038-03-3 | C21H24O6 |
|
| —— | 2-(2-isopropoxy-4-methoxy-phenyl)-4-oxo-4<i>H</i>-chromene-6-carboxylic acid | 66849-00-1 | C20H18O6 |
|
| —— | 3',4'-bis(benzyloxy)-3-(hexyloxy)-5,6,7-trimethoxyflavone | 134082-45-4 | C38H40O8 |
|
| —— | 2-(4-Methoxy-phenyl)-6-[(E)-3-(4-methoxy-phenyl)-acryloyl]-7-methyl-chromen-4-one | 131941-99-6 | C27H22O5 |
|
| —— | 4',4''',7,7''-tetrakis(benzyloxy)-5,5''-dihydroxy-3,3''-biflavanone | 1253959-28-2 | C58H46O10 |
|
| —— | 1,3-diethyl-5-(4-oxo-2-phenyl-4<i>H</i>-chromen-3-ylmethyl)-pyrimidine-2,4,6-trione | 37042-08-3 | C24H22N2O5 |
|
| —— | (2R,3S)-2-(3,4-dimethoxyphenyl)-8-mesityl-5,7-dimethoxychroman-3-ol | 1224595-36-1 | C28H32O6 |
|
| —— | 1462876-34-1 | C34H24Cl2O5 |
|
|
| —— | 8-Methoxy-13,13-bis(4-methoxyphenyl)-1',1',5',5'-tetramethylspiro[6,12-dioxahexacyclo[15.7.0.02,10.03,7.011,16.019,24]tetracosa-1(17),2,7,9,11(16),14,19(24),20,22-nonaene-18,3'-cyclohexane]-21-carbonitrile | 1259401-23-4 | C47H45NO5 |
|
| —— | 5'-Chloro-5,7-dihydroxy-3,2'-dimethoxyflavone | 95055-80-4 | C17H13ClO6 |
|
| —— | 3-hydroxy-5-[2-(3,4,5-trimethoxy-phenyl)-furo[3,2-b]pyridin-7-yl]-benzamide | 1360909-40-5 | C23H20N2O6 |
|
| —— | 4',7-Dibenzyloxy-3',5,6,8-tetramethoxy-flavon | 4396-78-5 | C33H30O8 |
|
| —— | (2R,3S)-trans-3',4'-dimethoxyflavan-3-ol | 1196870-24-2 | C17H18O4 |
|
| —— | 3-hydroxy-6-phenylmethoxy-2-(4-phenylmethoxyphenyl)chromen-4-one | 132020-69-0 | C29H22O5 |
|
| —— | 4H-1-Benzopyran-4-one,3,5-dihydroxy-6,8-dimethoxy-2-[4-methoxy-3-(phenylmethoxy)phenyl]-7-(phenylmethoxy)- | 176662-30-9 | C32H28O9 |
|
| —— | 2-(2,4-Dimethoxy-phenyl)-8-[5-(2,4-dimethoxy-phenyl)-6-(2-hydroxy-4-methoxy-benzoyl)-3-methyl-cyclohex-2-enyl]-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one | 75629-25-3 | C47H50O11 |
|
| —— | (2S,3R)-trans-3'-bromo-4',5'-dimethoxyflavan-3-ol | 1196870-35-5 | C17H17BrO4 |
|
| —— | 6-Benzoyl-8-methyl-3',4'-methylendioxy-flavonolacetat | 95953-26-7 | C26H18O7 |
|
| —— | 2-[3,4-bis(phenylmethoxy)phenyl]-5,6,7-trimethoxy-3-octylchromen-4-one | 134082-19-2 | C40H44O7 |
|
| —— | 2-(4-methoxyphenyl)-3-benzyloxy-6-propionylchromone | 141070-49-7 | C26H22O5 |
|
| —— | 2-(4-Chloro-phenyl)-3-methoxy-6-propionyl-chromen-4-one | 141070-48-6 | C19H15ClO4 |
|
| —— | 5,7-Diacetoxy-6,8-dimethylflavanon | 51621-51-3 | C21H20O6 |
|
| —— | 3-Morpholin-4-ylmethyl-2-phenyl-chroman-4-one; hydrochloride | 33460-87-6 | C20H21NO3*ClH |
|
| —— | acetic acid 4,5-diacetoxy-6-acetoxymethyl-2-[2-(3,4-bis-benzyloxy-phenyl)-4-oxo-4H-chromen-3-yloxy]-tetrahydro-pyran-3-yl ester | 918309-45-2 | C43H40O14 |
|
| —— | 2',4'-diisopropyloxy-5,7,8-trimethoxyflavone | 101909-61-9 | C24H28O7 |
|
| —— | Acetic acid 2-(3-acetoxy-4-methoxy-phenyl)-7-((2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-3-methoxy-tetrahydro-pyran-2-yloxy)-4-oxo-chroman-5-yl ester | 67322-19-4 | C33H36O16 |
|
| —— | 7-((2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-hydroxymethyl-4-methoxy-tetrahydro-pyran-2-yloxy)-5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-chroman-4-one | 67322-15-0 | C23H26O11 |
|
| —— | isovitexin heptaacetate | 20197-52-8 | C35H34O17 |
|
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