黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| —— | benzyl (thiophen-3-yl(tosyl)methyl)carbamate | 1244966-59-3 | C23H15ClO4 |
|
| —— | 2-(4-chlorophenyl)-7-hydroxy-5,8-dimethoxychromen-4-one | 884867-38-3 | C17H13ClO5 |
|
| —— | 2-(3-phenoxyphenyl)-4,9-dihydrocyclohepta[b]pyran-4,9-dione | 491871-23-9 | C22H14O4 |
|
| —— | 3,3-dibromo-6-methyl-2-phenyl-chroman-4-one | 101422-92-8 | C16H12Br2O2 |
|
| —— | trans-3.7.8.3'.4'-Pentamethoxyflavanon | 20754-52-3 | C20H22O7 |
|
| —— | 3,3-diphenyl-13-hydroxy-13-(2-oxo-2-ethoxyethyl)-1H-indeno[2,1-f]naphtho[1,2-b]pyran | 200884-11-3 | C36H28O4 |
|
| —— | 5-[4-(3-hydroxypropoxy)phenyl]-11,12-dihydro-5H-6,13-dioxa-benzo[3,4]cyclohepta[1,2-a]naphthal ene-2,8-diol | 1157856-59-1 | C26H24O6 |
|
| —— | 2',4'-diisopropyloxy-5,5',6,7,8-pentamethoxyflavone | 96410-40-1 | C26H32O9 |
|
| —— | (-)-toluene-4-sulfonic acid 4-oxo-2-phenylchroman-7-yl ester | 1610536-10-1 | C22H18O5S |
|
| —— | (2R,3R)-2-(3-methoxy-4,5-bis(2-nitrophenylsulfonyloxy)phenyl)-5,7-bis(2-nitrophenylsulfonyloxy)-chroman-3-yl 3-methoxy-4,5-bis(2-nitrophenylsulfonyloxy)benzoate | 1186527-33-2 | C60H40N6O35S6 |
|
| —— | 7-hydroxy-5,8-dimethoxy-2-(4-methylphenyl)chromen-4-one | 884867-35-0 | C18H16O5 |
|
| —— | 2-((7-hydroxy-5-methoxy-4-oxo-2-phenyl-4H-chromen-6-yl)methylene)hydrazinecarbothioamide | 1260141-35-2 | C18H15N3O4S |
|
| —— | Malvidin 3-glucoside 4-pyruvic acid chloride | 209862-95-3 | C26H25ClO14 |
|
| —— | 5-Methoxy-4',6,7-trihydroxyflavanon | 53000-15-0 | C16H14O6 |
|
| —— | 6-(prop-2-yn-1-yloxy)flavone | 1384952-85-5 | C18H12O3 |
|
| —— | 4-[3-(Hexopyranosyloxy)-5,7-dihydroxy-1-benzopyran-1-ium-2-yl]-2-hydroxy-6-methoxyphenolate--hydrogen chloride (1/1) | 26984-08-7 | C22H23ClO12 |
|
| —— | diethyl 2-<(4-oxo-2-phenyl-4H-1-benzopyran-8-yl)methyl>propanedioate | 87626-99-1 | C23H22O6 |
|
| —— | Acetic acid (S)-7-acetoxy-2-[3,4-diacetoxy-5-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-4-oxo-chroman-5-yl ester | 78335-35-0 | C37H38O20 |
|
| —— | 2-(3,4,5-trifluorophenyl)-2H-chromene | 1362479-23-9 | C15H9F3O |
|
| —— | 7-amino-8-hydroxy-3-iodo-2-phenyl-chromen-4-one | 1279089-68-7 | C15H10INO3 |
|
| —— | 7-<(2-Dibutylamino-ethyl)-carbamoylmethoxy>-4-oxo-2-phenyl-4H-chromen | 106041-43-4 | C27H34N2O4 |
|
| —— | 3-N-acetylaminomethylidene-flavanone | 99111-31-6 | C18H15NO3 |
|
| —— | 3',4'-methylenedioxy-7-methoxymethoxy-6-(3,3-dimethyl)allylflavanone | 1352547-23-9 | C23H24O6 |
|
| —— | 7-hydroxy-2-(4-hydroxyphenyl)-6-[(E)-2-(4-nitrophenyl)diazen-1-yl]-4H-chromen-4-one | 1565623-12-2 | C21H13N3O6 |
|
| —— | 7-benzyloxy-2-(4-methoxy-phenyl)-chroman-4-one | 132351-65-6 | C23H20O4 |
|
| —— | 5-hydroxy-4-methyl-2-phenyl-chromen-7-one | 855286-21-4 | C16H12O3 |
|
| —— | {1-[4-(5-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester | 1279087-52-3 | C30H28FNO4 |
|
| —— | R-5-{4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl}-11,12-dihydro-5H-6,13-dioxa-benzo[3,4]cyclohepta [1,2-a]naphthalene-2,8-diol | 1157856-74-0 | C30H32N2O5 |
|
| —— | 7-(3-cyclohexylamino-2-hydroxypropoxy) flavone hydrochloride | 84858-36-6 | C24H27NO4*ClH |
|
| —— | 2,3-cis-3,4-cis-4-phenoxyflavan-3-ol | 35094-94-1 | C21H18O3 |
|
| —— | 1104380-52-0 | C85H92O10Si4 |
|
|
| —— | 4-(2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolin-5-yl)phenol | 389090-32-8 | C26H25NO3 |
|
| —— | (7R,8R)-8-(2,4-dihydroxyphenyl)-5,7-dihydroxy-2,2-dimethyl-7,8-dihydropyrano[3,2-g]chromen-6-one | 1396769-35-9 | C20H18O7 |
|
| —— | 3'-benzyloxy-5,6,7,4'-tetramethoxyflavanone | 111670-58-7 | C26H26O7 |
|
| —— | 4-[7-[(4-Chlorophenyl)methoxy]-3,5-dihydroxy-4-oxo-chromen-2-yl]benzonitrile | 1254040-66-8 | C23H14ClNO5 |
|
| —— | 3-Methyl-flavon-carbonsaeure-(8)-<2-diisopropylamino-aethylester> | 118764-67-3 | C25H29NO4 |
|
| —— | (E)-4'-methyl-3-styrylflavone | 1373355-46-4 | C24H18O2 |
|
| —— | Acetic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-4-(2-ethoxy-ethoxy)-chroman-3-yl ester | 882867-44-9 | C49H48O9 |
|
| —— | 3-acetoxy-7-methoxy-2-phenyl-chroman-4-one | 4539-23-5 | C18H16O5 |
|
| —— | 1156495-03-2 | C32H31NO15 |
|
|
| —— | Acetic acid 2-(4-hydroxy-3-methyl-phenyl)-7-methoxy-chroman-3-yl ester | 116139-53-8 | C19H20O5 |
|
| —— | (2S,3R,4R,5S,6S)-2-(((2S,3R,4S,5R,6R)-4,5-diacetoxy-2-((5-acetoxy-2-(3,4-dimethoxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-6-(acetoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate | 34280-04-1 | C43H48O22 |
|
| —— | Acetic acid (4bR,10aR,4'bS,10'aS)-4'b-acetoxy-2,8,2',8'-tetramethoxy-10a,10'a-dimethyl-5,5'-dioxo-4'b,10'a-dihydro-5H,5'H-[3,3']bi[10,11-dioxa-benzo[b]fluorenyl]-4b-yl ester | 70387-15-4 | C40H34O14 |
|
| —— | 5,2'-Dihydroxy-6,7-dimethoxyflavon-diacetat | 73034-29-4 | C21H18O8 |
|
| —— | 2-[3-(3-methoxyphenyl)-3-[2-(3-methoxyphenyl)-3,4-dihydro-2H-chromen-6-yl]propyl]phenol | 140480-01-9 | C32H32O4 |
|
| —— | 7-Benzyloxy-5-hydroxy-6,3',4'-trimethoxy-flavon | 34899-28-0 | C25H22O7 |
|
| —— | Meralein sodium | 4386-35-0 | C19H10HgI2NaO7S |
|
| —— | 2-(4-cyanophenyl)-4,9-dihydrocyclohepta[b]pyran-4,9-dione | 1206731-49-8 | C17H9NO3 |
|
| —— | vexibidin | 52483-02-0 | C26H30O6 |
|
| —— | (S)-5-Hydroxy-7-methoxy-8-(3-methyl-butyl)-2-phenyl-chroman-4-one | 138590-95-1 | C21H24O4 |
|
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