黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| —— | 1104380-48-4 | C83H86O10Si3 |
|
|
| —— | 6-[2-(3,5-difluorophenyl)chroman-6-yloxy]-pyridin-3-ylamine | 728934-70-1 | C20H16F2N2O2 |
|
| —— | (2S,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol | 125136-18-7 | C21H18O8 |
|
| —— | (S)-3-tert-butoxycarbonylamino-N-[6-(2-phenylchroman-6-yloxy)pyridin-3-yl]succinamic acid tert-butyl ester | 728936-34-3 | C33H39N3O7 |
|
| —— | 7-Acetoxy-6-[3-(2-acetoxy-phenyl)-1-(4-methoxy-phenyl)-propyl]-2-phenyl-chroman | 121966-52-7 | C35H34O6 |
|
| —— | 1-[2-(1,3-Benzodioxol-5-yl)-3-methoxy-6-methyl-4-oxochromen-8-yl]pyrrolidin-2-one | 934374-23-9 | C22H19NO6 |
|
| —— | 6-bromo-2-(5-bromo-2-methoxy-phenyl)-benzo[<i>h</i>]chromen-4-one | 112400-84-7 | C20H12Br2O3 |
|
| —— | 5-(3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl)-1,2,3-benzenetriol | 531-04-4 | C15H14O5 |
|
| —— | 7-benzyloxy-3',4',5,6-tetramethoxy flavanone | 203191-59-7 | C26H26O7 |
|
| —— | 2,3-dihydro-5,7-dimethoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one | 101395-13-5 | C20H22O5 |
|
| —— | (R)-2-(3-methoxyphenyl)-4-(nitromethyl)-4H-chromene-3-carbaldehyde | 1367053-89-1 | C18H15NO5 |
|
| —— | cyanidin 3-O-[2-O-(2-O-(trans-feruloyl)-β-xylosyl)-6-O-(trans-feruloyl)-β-glucoside]-5-O-[6-O-(malonyl)-β-glucoside] | 1647116-56-0 | C55H57O29 |
|
| —— | 4-methyl-N-(3-(5,6,7-trimethoxy-4-oxo-4H-chromen-2-yl)phenyl)benzenesulfonamide | 1467668-61-6 | C25H23NO7S |
|
| —— | 2-(4-chlorophenyl)-3-(4-chlorophenyl)sulfonyl-6-methylchromen-4-one | 87127-81-9 | C22H14Cl2O4S |
|
| —— | tert-butyl-[[(19S)-5-[tert-butyl(dimethyl)silyl]oxy-19-[4-(2-iodoethoxy)phenyl]-8,18-dioxatetracyclo[9.8.0.02,7.012,17]nonadeca-1(11),2(7),3,5,12(17),13,15-heptaen-15-yl]oxy]-dimethylsilane | 1157856-76-2 | C37H49IO5Si2 |
|
| —— | 3-iodo-7,8-dimethoxy-2-phenyl-chromen-4-one | 1279087-55-6 | C17H13IO4 |
|
| —— | 7-hydroxy-6-n-pentyloxy flavone | 203190-96-9 | C20H20O4 |
|
| —— | 3-Hydroxy-5,7-dimethoxyflavone 3-glucuronide | 1242087-50-8 | C23H22O11 |
|
| —— | (2<i>S</i>)-2<i>r</i>chloro-3<i>t</i>-(3,4-dimethoxy-phenyl)-5,7-dimethoxy-chroman | 2174-55-2 | C19H21ClO5 |
|
| —— | 2-(4-aminophenyl)-8-prop-2-enylchromen-4-one | 851774-74-8 | C18H15NO2 |
|
| —— | 6-Chloro-3-hydroxy-8-methyl-2-(4-phenylmethoxyphenyl)chromen-4-one | 111391-60-7 | C23H17ClO4 |
|
| —— | Methyl-2-(4-nitrophenyl)-4-oxo-chroman-6-carboxylat | 145603-01-6 | C17H13NO6 |
|
| —— | [(2R,3S)-2-(4-chlorophenyl)-4-oxo-2,3-dihydrochromen-3-yl] thiocyanate | 94953-56-7 | C16H10ClNO2S |
|
| —— | 3,8-dibromo-7-butoxy-2-(4-methoxyphenyl)-6-nitrochromen-4-one | 139589-43-8 | C20H17Br2NO6 |
|
| —— | 3,5,7,3',2'',3'',4'',6''-octa-O-acetyl-(+)-catechin 4'-O-β-D-glucoside | 1209469-11-3 | C37H40O19 |
|
| —— | (-)-(6S,6aR,10S,10aR)-ethyl 4-hydroxy-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate | 1631166-07-8 | C17H19NO6 |
|
| —— | (Z)-2-(2-chlorophenyl)-3-((naphthalen-1-ylmethylamino)methylene)chroman-4-one | 1430097-85-0 | C27H20ClNO2 |
|
| —— | 4,9-dimethoxy-7-<i>p</i>-tolyl-6,7-dihydro-furo[3,2-<i>g</i>]chromen-5-one | 62061-98-7 | C20H18O5 |
|
| —— | (2R,3R)-tert-butyl 3-fluoro-4-oxo-2-phenyl-3,4-dihydro-2H-chromene-3-carboxylate | 1207514-98-4 | C20H19FO4 |
|
| —— | 8-(1',1'-dimethylallyl)-7-hydroxy-3-methylflavone | 77609-93-9 | C21H20O3 |
|
| —— | 2,2-dimethyl-7-[2-(trifluoromethoxy)phenyl]-2H-chromene-3,4-dione | 1393844-28-4 | C18H13F3O4 |
|
| —— | 3,5,7,3',4'-Pentaacetoxyflav-3-en | 6900-64-7 | C25H22O11 |
|
| —— | 4',7-dimethoxyflavylium chloride | 89512-39-0 | C17H15O3*Cl |
|
| —— | 8,4'-dimethoxyflavylium chloride | 29822-67-1 | C17H15O3*Cl |
|
| —— | 1609153-70-9 | C31H36N2O10 |
|
|
| —— | 1400900-14-2 | C30H23Cl2NO3S |
|
|
| —— | 5,8-Dihydroxy-6,7,3',4'-tetramethoxy-flavanon | 97081-09-9 | C19H20O8 |
|
| —— | 2-(3,5-dimethoxy-4-methoxymethoxy-phenyl)-3-hydroxy-6-methoxy-chromen-4-one | 109979-42-2 | C20H20O8 |
|
| —— | 1204484-88-7 | C63H56N4O7 |
|
|
| —— | 5,7-dimethoxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-2-(3-nitrophenyl)-4H-benzopyran-4-one | 358739-62-5 | C23H24N2O7 |
|
| —— | 1333408-74-4 | C26H18BrFO4 |
|
|
| —— | 6-n-butyloxy-7-hydroxy-3',4',5-trimethoxy flavone | 203190-94-7 | C22H24O7 |
|
| —— | 7-carboxymethyloxy-6-n-pentyloxy flavanone | 203191-12-2 | C22H24O6 |
|
| —— | {4-[2,8-bis-(tert-butyldimethylsilanyloxy)-11,12-dihydro-5H-6,13-dioxabenzo[3,4]cyclohepta[1, 2-a]naphthalen-5-yl]phenoxy}acetic acid | 1056053-25-8 | C37H48O7Si2 |
|
| —— | 3-{4-[2,8-bis-(tert-butyldimethylsilanyloxy)-11,12-dihydro-5H-6,13-dioxabenzo[3,4]cyclohepta[ 1,2-a]naphthalen-5-yl]phenoxy}propionic acid methyl ester | 1056053-62-3 | C39H52O7Si2 |
|
| —— | 4'-Methoxy-flavan-3,4-diol | 60094-50-0 | C16H16O4 |
|
| —— | (2R,3S,4S)-2-(3,4-bis((phenyl-d5)methoxy-d2)phenyl)-4-(2-ethoxyethoxy)-5,7-bis((phenyl-d5)methoxy-d2)chroman-3-ol | 1438268-67-7 | C47H46O8 |
|
| —— | 4-[5-chloro-3-methylbenzofuran-2-yl]phenyl-β-L-fucopyranoside | 1609690-86-9 | C21H21ClO6 |
|
| —— | IBS_STOCK6S-25601 | 92606-68-3 | C24H26N2O3 |
|
| —— | {(S)-2-hydroxy-1-[6-(2-phenylchroman-6-yloxy)pyridin-3-ylcarbamoyl]-ethyl}carbamic acid tert-butyl ester | 728936-11-6 | C28H31N3O6 |
|
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- 11
- 12
- 13
- 14
- 15
- 16
- 17
- 18
- 19
- 20
- 21
- 22
- 23
- 24
- 25
- 26
- 27
- 28
- 29
- 30
- 31
- 32
- 33
- 34
- 35
- 36
- 37
- 38
- 39
- 40
- 41
- 42
- 43
- 44
- 45
- 46
- 47
- 48
- 49
- 50
- 51
- 52
- 53
- 54
- 55
- 56
- 57
- 58
- 59
- 60
- 61
- 62
- 63
- 64
- 65
- 66
- 67
- 68
- 69
- 70
- 71
- 72
- 73
- 74
- 75
- 76
- 77
- 78
- 79
- 80
- 81
- 82
- 83
- 84
- 85
- 86
- 87
- 88
- 89
- 90
- 91
- 92
- 93
- 94
- 95
- 96
- 97
- 98
- 99
- 100
- 101
- 102
- 103
- 104
- 105
- 106
- 107
- 108
- 109
- 110
- 111
- 112
- 113
- 114
- 115
- 116
- 117
- 118
- 119
- 120
- 121
- 122
- 123
- 124
- 125
- 126
- 127
- 128
- 129
- 130
- 131
- 132
- 133
- 134
- 135
- 136
- 137
- 138
- 139
- 140
- 141
- 142
- 143
- 144
- 145
- 146
- 147
- 148
- 149
- 150
- 151
- 152
- 153
- 154
- 155
- 156
- 157
- 158
- 159
- 160
- 161
- 162
- 163
- 164
- 165
- 166
- 167
- 168
- 169
- 170
- 171
- 172
- 173
- 174
- 175
- 176
- 177
- 178
- 179
- 180
- 181
- 182
- 183
- 184
- 185
- 186
- 187
- 188
- 189
- 190
- 191
- 192
- 193
- 194
- 195
- 196
- 197
- 198
- 199
- 200
- 201
- 202
- 203
- 204
- 205
- 206
- 207
- 208
- 209
- 210
- 211
- 212
- 213
- 214
- 215
- 216
- 217
- 218
- 219
- 220
- 221
- 222
- 223
- 224
- 225
- 226
- 227
- 228
- 229
- 230
- 231
- 232
- 233
- 234
- 235
- 236
- 237
- 238
- 239
- 240
- 241
- 242
- 243
- 244
- 245
- 246
- 247
- 248
- 249
- 250
- 251
- 252
- 253
- 254
- 255
- 256
- 257
- 258
- 259
- 260
- 261
- 262
- 263
- 264
- 265
- 266
- 267
- 268
- 269
- 270
- 271
- 272
- 273
- 274
- 275
- 276
- 277
- 278
- 279
- 280
- 281
- 282
- 283
- 284
- 285
- 286
- 287
- 288
- 289
- 290
- 291
- 292
- 293
- 294
- 295
- 296
- 297
- 298
- 299
- 300
联系我们
关注我们
公众号
