黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | 1198596-27-8 | C41H60O5Si2 | |
| —— | (2R)-6-bromo-2-(2-nitrophenyl)-2H-chromene-3-carbaldehyde | 1608094-83-2 | C16H10BrNO4 |
| —— | 5,7-dicarboxymethoxy-2-(3-carboxymethoxy-4-methoxyphenyl)-4H-1-benzopyran-4-one | 198886-04-3 | C22H18O12 |
| —— | 3-Hydroxy-3',4',5',7-tetramethoxyflavan | 99100-11-5 | C19H22O6 |
| —— | 1204484-93-4 | C64H58N4O8 | |
| —— | (2R,3R)-5,7-bis(benzyloxy)-2-(3,4,5-tris(benzyl-oxy)phenyl)chroman-3-yl 4-((dibenzyloxy)phosphoryl-oxy)benzoate | 1338810-07-3 | C71H61O12P |
| —— | 6-C-Prenyl-5-hydroxy-7,4'-dimethoxyflavon | 68634-26-4 | C22H22O5 |
| —— | 2-(2,3,4-trimethoxy-phenyl)-chroman-4-ol | 69471-22-3 | C18H20O5 |
| —— | 4H-1-Benzopyran-4-one,2-(1,3-benzodioxol-5-yl)-2,3-dihydro-7,8-dimethoxy- | 919094-48-7 | C18H16O6 |
| —— | 3,5,8-trimethoxy-2-phenyl-chromen-4-one | 727413-36-7 | C18H16O5 |
| —— | 4'-acetoxy-6-C-(tri-O-acetyl-β-D-xylopyranosyl)-8-C-(tri-O-acetyl-α-L-arabinopyranosyl)-5,7-di-hydroxyflavanone | 1253227-47-2 | C39H42O20 |
| —— | 4'-Methoxy-7-methylflavan | 41786-45-2 | C17H18O2 |
| —— | 1062237-72-2 | C27H17ClO3 | |
| —— | 6-carboxy-2'-(2-ethoxy-ethoxy)-flavone | 57009-27-5 | C20H18O6 |
| —— | 2-(2,5-dimethoxy-phenyl)-4-oxo-4<i>H</i>-chromene-6-carboxylic acid | 66848-95-1 | C18H14O6 |
| —— | 2-methyl-2-morpholin-4-yl-3-phenyl-2,3-dihydro-benzofuran-5-ol | 32558-92-2 | C19H21NO3 |
| —— | (2R,3R)-cis-3-acetoxy-3',4'-dimethoxyflavan | 1196870-54-8 | C19H20O5 |
| —— | 4-oxo-2-phenyl-chroman-5-carboxylic acid methyl ester | 69187-22-0 | C17H14O4 |
| —— | 3'-Acetoxy-7,4'-dimethoxyflavon | 31526-67-7 | C19H16O6 |
| —— | 2-(9-phenanthrenyl)-chroman-4-one | 84999-74-6 | C23H16O2 |
| —— | 6,8-di-C-(β-D-xylopyranosyl)-5,7,4'-trihydroxy-3',5'-dimethoxyflavone | 1253227-69-8 | C27H30O15 |
| —— | α-Naphthothioneflavone | 14882-98-5 | C19H12OS |
| —— | 7-Benzyloxy-2-(4-benzyloxy-3-methoxy-phenyl)-3-hydroxy-5,6,8-trimethoxy-chromen-4-one | 176662-14-9 | C33H30O9 |
| —— | 5,7-dimethoxy-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-2-(2,3-dimethoxyphenyl)-4H-chromen-4-one | 1254302-05-0 | C25H27NO6 |
| —— | 3-hydroxy-5-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one | 29219-06-5 | C17H14O5 |
| —— | 6-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-3,7-dimethoxy-4-oxo-4H-chromene-5-carbaldehyde | 853930-63-9 | C19H16O8 |
| —— | 5,7-dimethoxy-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-2-(2,3,4-trimethoxyphenyl)-4H-chromen-4-one | 1254302-06-1 | C26H29NO7 |
| —— | 8-methoxy-4-phenyl-1,2,3,3a,4,9b-hexahydro-cyclopenta[<i>c</i>]chromene | 61076-51-5 | C19H20O2 |
| —— | Quercetin-3-neohesperidoside-7-rhamnoside | 161993-01-7 | C33H40O20 |
| —— | 8-Bromo-6-chloro-2-(4-chlorophenyl)-3-iodochromen-4-one | 360566-70-7 | C15H6BrCl2IO2 |
| —— | (E)-methyl 3-(7-methoxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-3-yl)acrylate | 1412410-86-6 | C21H18O6 |
| —— | (R)-3-(3,4-Dimethoxy-phenyl)-3-[(2R,3R)-2-(3,4-dimethoxy-phenyl)-3-hydroxy-5,7-dimethoxy-chroman-8-yl]-propionic acid methyl ester | 85022-74-8 | C31H36O10 |
| —— | 6-Acetyl-3-butyl-2-phenyl-chromen-4-one | 92757-76-1 | C21H20O3 |
| —— | 3,2',5'-Triacetoxy-7,8-dimethoxy-flavon | 112599-41-4 | C23H20O10 |
| —— | 3,3-bis(4-methoxyphenyl)-10,12-dibromo-13,13-dimethyl-3H,13H-indeno[2',3':3,4]naphtho[1,2-b]pyran | 1381922-53-7 | C36H28Br2O3 |
| —— | 7,8,3',4'-Tetraacetoxy-3-methoxyflavon | 38510-51-9 | C24H20O11 |
| —— | 2-(3,4-dimethoxy-phenyl)-4-oxo-4<i>H</i>-chromene-6-carboxylic acid | 66848-96-2 | C18H14O6 |
| —— | 1187019-11-9 | C15H10O5*C56H98O35 | |
| —— | 4'-acetoxy-6-C-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-8-C-(2,3,4-tri-O-acetyl-β-D-arabinopyranosyl)-5,7-dihydroxyflavan | 1253227-82-5 | C39H44O19 |
| —— | 4,4-Difluoro-8-methoxy-13,13-bis(4-methoxyphenyl)-1',1',5',5'-tetramethylspiro[6,12-dioxahexacyclo[15.7.0.02,10.03,7.011,16.019,24]tetracosa-1(17),2,7,9,11(16),14,19,21,23-nonaene-18,3'-cyclohexane] | 1259401-12-1 | C46H44F2O5 |
| —— | Lucenin-2-permethylether | 38953-91-2 | C39H54O16 |
| —— | 5,7-diacetoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one | 18085-94-4 | C22H20O9 |
| —— | 7-O-methylglabranin | 75350-44-6 | C21H22O4 |
| —— | (+/-)-3,4,8,9-Tetrahydro-5-hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,10H-benzo<1,2-b:3,4-b'>dipyran-10-on | 68634-19-5 | C20H20O5 |
| —— | 8-Methoxy-13,13-bis(4-methoxyphenyl)-18-methyl-6,12-dioxahexacyclo[15.7.0.02,10.03,7.011,16.019,24]tetracosa-1(17),2,7,9,11(16),14,19,21,23-nonaen-18-ol | 1259401-29-0 | C38H32O6 |
| —— | 6,4'-Dibenzyloxy-7,3'-dimethoxyflavone | 82298-10-0 | C31H26O6 |
| —— | 4'-Methoxy-5,7-dimethyl-flavon | 109253-91-0 | C18H16O3 |
| —— | 2-[3-hydroxy-2-(4-hydroxy-3-methylphenyl)-6-methyl-4-oxo-4H-chromen-8-yl]-1λ6-isothiazolidin-1,1-dione | 372102-72-2 | C20H19NO6S |
| —— | 4',5,7-tri-O-benzyl-kaempferol 3-O-(2''-O-benzyl-α-L-rhamnopyranoside) | 942942-49-6 | C49H44O10 |
| —— | 2-[4-(2-azidoethoxy)phenyl]-3-hydroxy-4H-chromen-4-one | 1266134-27-3 | C17H13N3O4 |
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