黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | 5,7-Diacetoxy-2'-methoxy-flavanon | 94550-26-2 | C20H18O7 |
| —— | 5-acetoxy-2-(4-methoxy-phenyl)-8-nitro-chromen-4-one | 130955-73-6 | C18H13NO7 |
| —— | 2-(4-benzyloxy-3-methoxy-phenyl)-3-hydroxy-2,3-dihydro-benzo[<i>h</i>]chromen-4-one | 122384-92-3 | C27H22O5 |
| —— | 7,4'-diacetyloxy-5-hydroxy-3,3'-dimethoxyflavone | 124458-93-1 | C21H18O9 |
| —— | 4'-dimethylamino-3-methylene flavanone | 77038-24-5 | C18H17NO2 |
| —— | 3'-benzyl-7-(benzyloxy)-4'-hydroxyflavanone | 1209470-06-3 | C29H24O4 |
| —— | N-[2-[2-(difluoromethoxy)phenyl]-4-oxochromen-8-yl]-1,3-thiazole-4-carboxamide | 1219445-64-3 | C20H12F2N2O4S |
| —— | 7-Chlor-6-sulfamoylflavon | 93944-96-8 | C15H10ClNO4S |
| —— | 5-Hydroxy-7-methoxyflavanon-2,4-dinitrophenylhydrazon | 96259-93-7 | C22H18N4O7 |
| —— | 7-Fluor-flavonol-(3) | 2647-26-9 | C15H9FO3 |
| —— | 2-{3-(benzyloxy)-2-[4-(benzyloxy)-3-methylphenyl]-6-methyl-4-oxo-4H-chromen-8-yl}-1λ6-isothiazolidin-1,1-dione | 372102-71-1 | C34H31NO6S |
| —— | N-[2-(2,6-dichlorophenyl)-4-oxochromen-8-yl]-1,3-thiazole-4-carboxamide | 1219446-01-1 | C19H10Cl2N2O3S |
| —— | (R)-5,7-Dihydroxy-8-((1R,6R)-6-isopropyl-3-methyl-cyclohex-2-enyl)-2-phenyl-chroman-4-one | 123357-16-4 | C25H28O4 |
| —— | (+/-)-2,3-cis-3,4-cis-3,4,5,7,4'-pentaacetoxyflavan | 6056-04-8 | C25H24O11 |
| —— | 2,2-dimethylchroman-4-one (4-nitrophenyl)hydrazone | 586956-79-8 | C17H17N3O3 |
| —— | Acetic acid 5,7-diacetoxy-2-(5-chloro-2-methoxy-phenyl)-3-methoxy-4-oxo-4H-chromen-8-yl ester | 95055-85-9 | C23H19ClO10 |
| —— | 4'-Methoxy-6-methyl-2,3-trans-dihydro-flavanol | 5529-98-6 | C17H16O4 |
| —— | N-[2-(3-methylsulfonylphenyl)-4-oxochromen-8-yl]pyridine-2-carboxamide | 1219445-01-8 | C22H16N2O5S |
| —— | 4-(p-Methoxyphenyl)-5,6-benzoflavon-4-ol | 55977-20-3 | C26H20O3 |
| —— | 3,8-Dichlormethyl-7-methoxy-2-phenyl-chromen-4-on | 94330-49-1 | C18H14Cl2O3 |
| —— | 2'-Hydroxy-5-methoxy-flavonol | 92965-28-1 | C16H12O5 |
| —— | 1-(4-β-D-glucopyranosyloxy-2-hydroxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propane-1,3-dione | 122360-91-2 | C24H28O12 |
| —— | 6-hydroxy-2-(4-trifluoromethylphenyl)chroman-4-one | 488849-34-9 | C16H11F3O3 |
| —— | 8-Hydroxy-6-methyl-3-ethyl-flavon | 93875-72-0 | C18H16O3 |
| —— | 1417564-46-5 | C18H15ClO4 | |
| —— | 7-benzyloxy-5-hydroxy-8-methoxy-2-phenyl-chroman-4-one | 112599-20-9 | C23H20O5 |
| —— | 5-Hydroxy-7,2',4'-trimethoxy-6-isopentyl-3-carboxymethyl-flavon | 103169-79-5 | C25H28O8 |
| —— | 8-Methoxy-6-isopropyloxy-flavon | 95937-48-7 | C19H18O4 |
| —— | 6,8-dichloro-2-(4-fluorophenyl)-2H-chromene-3-carboxylic acid | 1448552-61-1 | C16H9Cl2FO3 |
| —— | 3-isopropyl-1,3-diphenyl-3H-naphtho[2,1-b]pyran | 1350930-25-4 | C28H24O |
| —— | 7-hydroxy-2-(4-hydroxyphenyl)-6-[(E)-2-phenyldiazen-1-yl]–4H-chromen-4-one | 1565622-88-9 | C21H14N2O4 |
| —— | FLAVONE-3-DIPHOSPHATE | 28464-44-0 | C15H12O9P2 |
| —— | [5,7,8-Trimethoxy-2-(4-methoxy-phenyl)-4-oxo-chroman-6-yl]-acetic acid | 79180-30-6 | C21H22O8 |
| —— | 2,3-dihydro-t-mesyloxy-c-3-methyl-r-2-phenyl-4H-1-benzopyran-4-one | 116703-60-7 | C17H16O5S |
| —— | [5-(4-nitrobenzoyl)oxy-2-(4-nitrophenyl)-4-oxochromen-7-yl] 4-nitrobenzoate | 110865-09-3 | C29H15N3O12 |
| —— | 5-Chloro-7-hydroxy-2-phenylchromen-4-one | 139027-49-9 | C15H9ClO3 |
| —— | 2-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-5-hydroxy-7-methoxy-chroman-4-one | 895918-19-1 | C22H28O5Si |
| —— | 5-acetoxy-2-(4-ethoxy-phenyl)-3,6,7-trimethoxy-chromen-4-one | 102752-18-1 | C22H22O8 |
| —— | 4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-8-(phenylmethoxy)- | 89456-30-4 | C26H24O7 |
| —— | 5-hydroxy-2-[4-(tetra-<i>O</i>-acetyl-β-D-glucopyranosyloxy)-phenyl]-chromen-4-one | 121356-07-8 | C29H28O13 |
| —— | 4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(iso-propylcarbamate) | 1609067-50-6 | C23H24N2O6 |
| —— | 5,7,8-trihydroxy-3-methoxy-2-(2-methoxy-phenyl)-chromen-4-one | 710338-75-3 | C17H14O7 |
| —— | (2S,3R,4R)-2-(3,4-Dimethoxy-phenyl)-7-methoxy-4-(2,4,6-trimethoxy-phenyl)-chroman-3-ol | 78284-56-7 | C27H30O8 |
| —— | [(1S,4R,5S,12S,13R)-13,16,18-trimethoxy-4,12-bis(4-methoxyphenyl)-8,14-dioxo-3,11,21-trioxapentacyclo[11.8.0.01,10.02,7.015,20]henicosa-2(7),9,15(20),16,18-pentaen-5-yl] acetate | 142674-72-4 | C37H34O12 |
| —— | 2',4'-dibenzyloxy-3,5,5',6,7-pentamethoxyflavone | 105827-33-6 | C34H32O9 |
| —— | 2-(2,4-cis-4'-methoxyflavan-4-yloxy)flavan | 95731-49-0 | C31H28O4 |
| —— | 3-(4-Oxo-2,3-dihydrobenzo[h]chromen-2-yl)benzonitrile | 1018784-07-0 | C20H13NO2 |
| —— | 8-<Formyl-(2-hydroxy-1-formyl-ethoxy)-methyl>-5.7.4'-trimethoxy-flavon | 95431-65-5 | C23H22O9 |
| —— | (+/-)-3',4',5',7-Tetraacetoxyflavan | 95431-68-8 | C23H22O9 |
| —— | 6-methyl-2-phenylchroman-4-one (4-nitrophenyl)hydrazone | 906461-51-6 | C22H19N3O3 |
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