黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| —— | 4'-Nitroisoxazolo(7,8)flavon | 42380-61-0 | C16H8N2O5 |
|
| —— | 2-(2-(3,4-dimethoxyphenyl)-7-hydroxy-4-oxo-4H-chromen-5-yl)acetic acid | 1389342-04-4 | C19H16O7 |
|
| —— | 4,6-diacetoxy-2,3,3-trimethyl-7-phenyl-2,3-dihydro-furo[3,2-<i>g</i>]chromen-5-one | 50403-04-8 | C24H22O7 |
|
| —— | 7-Methoxy-3,7''-biflavonyloxymethan | 66075-28-3 | C32H22O7 |
|
| —— | 2-[3,4-bis(phenylmethoxy)phenyl]-3,5,7-trihydroxy-8-methoxychromen-4-one | 117155-56-3 | C30H24O8 |
|
| —— | 7,7''-Dimethoxy-3,8''-biflavonyloxymethan | 66075-29-4 | C33H24O8 |
|
| —— | Acetic acid 2,3,3-trimethyl-5-oxo-7-phenyl-2,3-dihydro-5H-furo[3,2-g]chromen-4-yl ester | 50402-97-6 | C22H20O5 |
|
| —— | 4-Hydroxy-2,3,3-trimethyl-7-phenyl-2,3-dihydro-furo[2,3-f]chromen-9-one | 55390-57-3 | C20H18O4 |
|
| —— | Stachyoidinolacetat | 42345-20-0 | C25H24O7 |
|
| —— | methyl 3-[7-(acetyloxy)-5-hydroxy-6,8-bis(isobut-2-en-1-yl)-4-oxo-4H-chromen-2-yl]-6-methoxy-2-(isobut-2-en-1-yl)phenyl-2,3,4-tris-O-acetyl-β-D-glucuronate | 1188911-07-0 | C43H48O16 |
|
| —— | 6,8-dibromo-2-phenyl-2H-chromene | 1532560-36-3 | C15H10Br2O |
|
| —— | 9-[4-((5-hydroxy-7-methoxymethoxy)-4H-chromen-4-on-2-yl)phenyl]-3,6,9-trioxanonan-1-ol | 916330-97-7 | C23H26O9 |
|
| —— | 5,3'-diacetoxy-7,8,4',5'-tetramethoxyflavone | 76025-23-5 | C23H22O10 |
|
| —— | 6-nitro-2-(4-nitro-phenyl)-chroman-4-one | 26224-25-9 | C15H10N2O6 |
|
| —— | Octaacetyl-sphaerobiosid | 24951-68-6 | C43H46O22 |
|
| —— | 4'-Methylisoxazolo(7,8)flavon | 42345-48-2 | C17H11NO3 |
|
| —— | 7-benzo[1,3]dioxol-5-yl-8-hydroxy-3-methyl-chromeno[6,5-<i>d</i>]isoxazol-9-one | 49544-04-9 | C18H11NO6 |
|
| —— | 4',7''-Dimethoxy-3,8''-biflavonyloxymethan | 66075-33-0 | C33H24O8 |
|
| —— | 7,2',4'-trimethyl nor-kurarinone | 34987-84-3 | C28H34O6 |
|
| —— | 3-Acetoxy-5,7,3',4'-tetramethoxy-flav-3-en | 51168-43-5 | C21H22O7 |
|
| —— | 2.4-trans-7.8.4'-Trimethoxy-4-acetyloxyflavan | 50403-57-1 | C20H22O6 |
|
| —— | 5-O-Demethyldehydrostachyoidin | 42345-14-2 | C22H16O6 |
|
| —— | 3-(N-Benzoyl)-amino-4'-nitroflavanon | 41769-91-9 | C22H16N2O5 |
|
| —— | 5-hydroxy-3-methoxy-2-(4-methoxy-phenyl)-8,8-dimethyl-8<i>H</i>-pyrano[2,3-<i>f</i>]chromen-4-one | 55929-14-1 | C22H20O6 |
|
| —— | 3-isopropoxy-5-[2-(3,4,5-trimethoxy-phenyl)-furo[3,2-b]pyridin-7-yl]-benzoic acid methyl ester | 1360910-29-7 | C27H27NO7 |
|
| —— | (S)-5,7-Dihydroxy-6-methyl-2-phenyl-8-[(E)-(3-phenyl-acryloyl)]-chroman-4-one | 55743-16-3 | C25H20O5 |
|
| —— | 3-aminoflavone-8-methanol | 579525-34-1 | C16H13NO3 |
|
| —— | 3-(allyloxy)-2-{4-(allyloxy)-3-[(allyloxy)methyl]phenyl}-6-methyl-8-nitro-4H-chromen-4one | 372102-75-5 | C26H25NO7 |
|
| —— | 2-[4-(4-acetylamino-benzenesulfonylamino)-phenyl]-6-chloro-3-hydroxy-chromen-4-one | 42520-01-4 | C23H17ClN2O6S |
|
| —— | 4-Deuterio-4α-phenylsulfonyl-flavan | 55539-42-9 | C21H18O3S |
|
| —— | 2-(7-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-5-yl)acetic acid | 1389342-03-3 | C18H14O7 |
|
| —— | 3-acetoxy-6,8-dichloro-2-(3,4-dimethoxy-phenyl)-chromen-4-one | 101936-13-4 | C19H14Cl2O6 |
|
| —— | 10-Methyl-12-phenyl-8,9,10,11,11a,12-hexahydro-7-oxa-10-aza-benzo[a]anthracen-7a-ol | 22216-94-0 | C23H23NO2 |
|
| —— | 7-Benzyloxy-5,6-dimethoxy-2-phenyl-chroman-4-one | 54299-58-0 | C24H22O5 |
|
| —— | Acetic acid (2R,3R,4S)-2-phenyl-4-phenylsulfanyl-chroman-3-yl ester | 55539-30-5 | C23H20O3S |
|
| —— | 6,7,4'-Trimethoxyflavan | 41786-44-1 | C18H20O4 |
|
| —— | 1312891-99-8 | C15H10N2O4 |
|
|
| —— | 6-methyl-2,2'-diphenyl-3,7'-methanediyldioxy-bis-chromen-4-one | 55091-80-0 | C32H22O6 |
|
| —— | 5,8-Dimethoxy-7-(4-methoxy-phenyl)-[1,3]dioxolo[4,5-f]chromen-9-one | 62953-06-4 | C19H16O7 |
|
| —— | 5,7-O,O-Bisdemethyltachrosinol | 42345-04-0 | C20H18O6 |
|
| —— | 5-acetoxy-8-(5,5-dimethyl-4-oxo-4,5-dihydro-furan-3-yl)-7-methoxy-2-phenyl-chromen-4-one | 42344-93-4 | C24H20O7 |
|
| —— | 5-acetoxy-8,8-dimethyl-2-phenyl-9,10-dihydro-8<i>H</i>-pyrano[2,3-<i>f</i>]chromen-4-one | 55390-60-8 | C22H20O5 |
|
| —— | Acetic acid 5-(5,7-dimethoxy-4-oxo-4H-chromen-2-yl)-2-(3,4-dimethoxy-phenyl)-7-methoxy-2,3-dihydro-benzofuran-3-ylmethyl ester | 55607-50-6 | C31H30O10 |
|
| —— | 5-acetoxy-8,9,9-trimethyl-2-phenyl-8,9-dihydro-furo[2,3-<i>h</i>]chromen-4-one | 50402-99-8 | C22H20O5 |
|
| —— | 4-Deuterio-4α-phenylthioflavan | 55539-23-6 | C21H18OS |
|
| —— | 3,6,7-Trimethoxy-2-phenyl-chromenylium; chloride | 40357-55-9 | C18H17O4*Cl |
|
| —— | 8-chloro-3-hydroxy-4-oxo-2-(2,4,5-trimethoxyphenyl)-4Hchromene-6-carbonitrile | 1441772-11-7 | C19H14ClNO6 |
|
| —— | 5-hydroxy-3,7-dimethoxyflavanone oxime | 1227479-73-3 | C17H17NO5 |
|
| —— | myricetin 5,3,3',4',5'-pentamethyl ether | 54614-61-8 | C20H20O8 |
|
| —— | 5',8''-biluteolin octamethyl ether | 52222-77-2 | C38H34O12 |
|
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