黄酮类化合物
黄酮类化合物
定义与结构特征
黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注，主要包括：
- 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
- 抗炎效应：有助于减轻炎症反应，缓解症状。
- 心血管保护：可能通过多种机制改善心脑血管健康。
- 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | 7,3',4'-Tribenzyloxy-flavan-3r,4c-diol | 103268-54-8 | C36H32O6 |
| —— | 1462876-41-0 | C32H18Cl4O5 | |
| —— | 4-chloro-2-(4-methoxyphenyl)-6-methyl-2H-chromene-3-carbaldehyde | 1393598-14-5 | C18H15ClO3 |
| —— | 5-methoxy-2-(4-methoxy-phenyl)-8-methyl-chroman-4-one | 109559-11-7 | C18H18O4 |
| —— | 3,4'-Dihydroxy-5,7,8,3'-tetramethoxy-flavon | 7741-50-6 | C19H18O8 |
| —— | penta-O-acetyl-(-)-robinetinidol-(4β,2)-tri-O-acetylphloroglucinol | 119483-77-1 | C37H34O17 |
| —— | 5,6,7-triacetoxy-2-phenyl-chroman-4-one | 102478-29-5 | C21H18O8 |
| —— | 1-(2,3-diphenyl-2<i>H</i>-chromen-2-yl)-piperidine | 119570-83-1 | C26H25NO |
| —— | 2-(2H-chromen-2-yl)phenol | 17348-79-7 | C15H12O2 |
| —— | 6-acetoxy-2-(4-acetoxy-phenyl)-5,7-dimethoxy-chromen-4-one | 33077-61-1 | C21H18O8 |
| —— | 2-(4-chlorophenyl)-2-methyl-2,3-dihydro-2'H-spiro[chromene-4,5'-[1,3]oxazolidin]-2'-one | 1313611-49-2 | C18H16ClNO3 |
| —— | 3-hydroxy-2-(2-hydroxy-4-methoxy-phenyl)-5,7-dimethoxy-chromen-4-one | 93876-65-4 | C18H16O7 |
| —— | Acetic acid 7-acetoxy-8-[1-(4-acetoxy-phenyl)-ethyl]-3-methoxy-2-(4-methoxy-phenyl)-4-oxo-4H-chromen-5-yl ester | 99631-89-7 | C31H28O10 |
| —— | [2-acetyloxy-4-(7-acetyloxy-5-hydroxy-3,4-dihydro-2H-chromen-2-yl)phenyl] acetate | 128374-04-9 | C21H20O8 |
| —— | 4-[4-[14'-(4-Methoxyphenyl)-21',21'-bis(2-methylphenyl)spiro[1,3,3a,4,5,6,7,7a-octahydroindene-2,9'-15,22-dioxa-20-thiahexacyclo[15.7.0.02,10.03,8.011,16.019,23]tetracosa-1(24),2(10),3,5,7,11(16),12,17,19(23)-nonaene]-14'-yl]phenyl]morpholine | 1398417-22-5 | C60H55NO4S |
| —— | 1616280-23-9 | C36H24O7 | |
| —— | 2'-benzyloxy-3-hydroxy-4',5,5',6,7-pentamethoxyflavone | 105827-28-9 | C27H26O9 |
| —— | 2',3'''-Oxy-6,6'''-dinitro-bisflavon | 57476-55-8 | C30H16N2O9 |
| —— | 3,3,6-Trichloro-2-phenyl-chroman-4-one | 71993-27-6 | C15H9Cl3O2 |
| —— | 8-hydroxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one | 743466-69-5 | C18H16O6 |
| —— | 2-(2,4-Dimethoxy-phenyl)-5,8-dihydroxy-3,7-dimethoxy-chromen-4-one | 84757-51-7 | C19H18O8 |
| —— | 2-(4-Ethoxy-phenyl)-3-isopropoxy-4-oxo-4H-chromene-6-carboxylic acid | 72739-37-8 | C21H20O6 |
| —— | (R)-<(2R,3S)-2,3-trans-3,7-diacetoxy-8-<(2R,3S)-2,3-trans-3-acetoxy-3',4',7,8-tetramethoxyflavan-5-yl>-3',4',5-trimethoxyflavan> | 109671-63-8 | C43H46O15 |
| —— | 8-bromo-3-methyl-3-phenyl-2,3-dihydro-1H-naphtho[2,1-b]pyran | 1219801-70-3 | C20H17BrO |
| —— | prodistenidin B-2 | 120693-56-3 | C30H26O8 |
| —— | 4α-Methoxyflavan | 55539-20-3 | C16H16O2 |
| —— | 2-(1,3-benzodioxol-5-yl)-2-vinylchromane | 1449790-14-0 | C18H16O3 |
| —— | 5.7-Dihydroxy-3-isopropyl-flavon | 1093-79-4 | C18H16O4 |
| —— | 2'-Methoxy-5'-iodflavanon | 92855-07-7 | C16H13IO3 |
| —— | 8-chloro-2-(4-methoxyphenyl)chromen-4-one | 80973-01-9 | C16H11ClO3 |
| —— | 1417195-24-4 | C29H34O7 | |
| —— | (+/-)-2,3-trans-3,4-trans-4-hydroxy-3,5,7,4'-tetraacetoxyflavan | 132400-77-2 | C23H22O10 |
| —— | Acetylderivat von 6-Nitro-3'-chlor-4'-methoxy-flavonol | 101607-26-5 | C18H12ClNO7 |
| —— | 3-Hydroxy-2-<2-hydroxy-phenyl>-6-benzoyl-chromon | 113059-14-6 | C22H14O5 |
| —— | 3-Hydroxy-2-(3-methoxy-phenyl)-4-oxo-4H-chromene-6-carboxylic acid | 58540-02-6 | C17H12O6 |
| —— | 8-methyl-4-phenyl-4H-benzopyran[4,3-d][1,2,3]selenadiazole | 1266399-34-1 | C16H12N2OSe |
| —— | 3'-methoxy-4'-hydroxy-5,7-bis(methoxymethoxy)flavanone | 1304788-30-4 | C20H22O8 |
| —— | 8-chloromethyl-3-dimethylcarbamoylflavone | 579525-41-0 | C19H16ClNO3 |
| —— | 7-Methoxy-flavan-3,4-diol | 93435-06-4 | C16H16O4 |
| —— | 2-(3,4-dimethoxy-phenyl)-3-methoxy-8-methyl-furo[2,3-<i>h</i>]chromen-4-one | 114330-50-6 | C21H18O6 |
| —— | 6-acetylamino-7-methoxy-2-(2-methoxy-phenyl)-chroman-4-one | 109614-79-1 | C19H19NO5 |
| —— | 8-acetylamino-2-(2-methoxy-phenyl)-chroman-4-one | 132594-02-6 | C18H17NO4 |
| —— | 7-O-(3-Ethoxycarbonylpropyl)-3'-O-cyclopentyldiosmetin | 205524-00-1 | C27H30O8 |
| —— | (2S,3R)-6-chloro-2-(4-chlorophenyl)-4,4-dimethoxy-2,3-dihydrochromen-3-ol | 139006-35-2 | C17H16Cl2O4 |
| —— | 7-Hydroxy-5-pentadecyl-flavon | 96379-24-7 | C30H40O3 |
| —— | 3-Benzyloxy-7,4'-dimethoxy-flavon | 807-56-7 | C24H20O5 |
| —— | 1-(5,8-dimethyl-2,2-diphenyl-2H-chromen-6-yl)pyrrolidine | 1073241-61-8 | C27H27NO |
| —— | 14,14-Bis(4-methoxyphenyl)-1',1',5',5'-tetramethylspiro[15,22-dioxa-20-thiahexacyclo[15.7.0.02,10.03,8.011,16.019,23]tetracosa-1(24),2(10),3,5,7,11(16),12,17,19(23)-nonaene-9,3'-cyclohexane] | 1398415-99-0 | C44H42O4S |
| —— | 3-(5-oxo-2-phenyl-4,5-dihydro-3H-naphtho[1,8-bc]furan-4-yl)-2,3-dihydro-isoindol-1-one | 32855-63-3 | C25H17NO3 |
| —— | 2-(5-Bromo-2-hydroxyphenyl)chromen-4-one | 1453812-79-7 | C15H9BrO3 |
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