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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— theaflavate B —— C36H28O15
    theaflavate B
    —— neotheaflavate B —— C36H28O15
    neotheaflavate B
    —— (2R,4R)-2-(4-bromophenyl)-3,4-dihydro-2H-chromen-4-ol —— C15H13BrO2
    (2R,4R)-2-(4-bromophenyl)-3,4-dihydro-2H-chromen-4-ol
    —— 6-isothiocyanatomethyl-2-phenyl-4H-1-benzopyran-4-one —— C17H11NO2S
    6-isothiocyanatomethyl-2-phenyl-4H-1-benzopyran-4-one
    —— (E)-4-(4-oxo-4H-chromen-2-yl)-N'-((pyridin-3-yl)methylene)benzohydrazide —— C22H15N3O3
    (E)-4-(4-oxo-4H-chromen-2-yl)-N'-((pyridin-3-yl)methylene)benzohydrazide
    —— N-(2-Diethylaminoethyl)-4'-methoxyflavone-8-carboxamide —— C23H26N2O4
    N-(2-Diethylaminoethyl)-4'-methoxyflavone-8-carboxamide
    —— (-)-epigallocatechin gallate —— C23H20O10
    (-)-epigallocatechin gallate
    —— 4-amino-N-(5-methyl-isoxazol-3-yl)-N-[(4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl]benzenesulfonamide —— C26H21N3O5S
    4-amino-N-(5-methyl-isoxazol-3-yl)-N-[(4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl]benzenesulfonamide
    —— 2-(3',4'-dihydroxyphenyl)-5-hydroxy-3,7-di-(β-D-galactosyl)-4H-chromen-4-one —— C27H30O17
    2-(3',4'-dihydroxyphenyl)-5-hydroxy-3,7-di-(β-D-galactosyl)-4H-chromen-4-one
    —— (R,S)-{cis-3-[4-amino-5-(2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol —— C26H26N4O2
    (R,S)-{cis-3-[4-amino-5-(2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol
    —— {cis-3-[4-amino-5-((S)-2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol —— C26H26N4O2
    {cis-3-[4-amino-5-((S)-2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol
    —— {cis-3-[4-amino-5-((R)-2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol —— C26H26N4O2
    {cis-3-[4-amino-5-((R)-2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}methanol
    —— 3-[(2S*,3S*,4R*)-3-nitro-2-(3-fluorophenyl)phenylchroman-4-yl]-2-phenyl-1H-indole —— C29H21FN2O3
    3-[(2S*,3S*,4R*)-3-nitro-2-(3-fluorophenyl)phenylchroman-4-yl]-2-phenyl-1H-indole
    —— (+)-trans-2-(2-bromo-5-fluorophenyl)-8-(2-hydroxymethyl-1-methyl-pyrrolidin-3-yl)-5,7-dimethoxy-chromen-4-one —— C23H23BrFNO5
    (+)-trans-2-(2-bromo-5-fluorophenyl)-8-(2-hydroxymethyl-1-methyl-pyrrolidin-3-yl)-5,7-dimethoxy-chromen-4-one
    —— (-)-4β-(2-hydroxyethylsulfanyl)epicatechin —— C17H18O7S
    (-)-4β-(2-hydroxyethylsulfanyl)epicatechin
    —— (E)-4-(4-oxo-4H-chromen-2-yl)-N'-(2,3-dihydroxybenzylidene)benzohydrazide —— C23H16N2O5
    (E)-4-(4-oxo-4H-chromen-2-yl)-N'-(2,3-dihydroxybenzylidene)benzohydrazide
    —— 6,8-diododiosmetin —— C16H10I2O6
    6,8-diododiosmetin
    —— trans-ethyl 2-(4-chlorophenyl)-3-fluoro-4-oxochroman-3-carboxylate —— C18H14ClFO4
    trans-ethyl 2-(4-chlorophenyl)-3-fluoro-4-oxochroman-3-carboxylate
    —— 2-(4'-isothiocyanatomethyl-phenyl)-4H-1-benzopyran-4-one —— C17H11NO2S
    2-(4'-isothiocyanatomethyl-phenyl)-4H-1-benzopyran-4-one
    —— 3-(2,3-dichlorophenyl)-1H-benzo[f]chromen-1-one —— C19H10Cl2O2
    3-(2,3-dichlorophenyl)-1H-benzo[f]chromen-1-one
    —— rhamnazin 3-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranoside —— C28H32O15
    rhamnazin 3-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranoside
    —— 2-[4-[N-(tert-butoxycarbonyl)-N-methoxymethylamino]-3-fluorophenyl]-6,8-difluoro-5-(4-methyl-3-pentenylamino)-4H-1-benzopyran-4-one —— C28H31F3N2O5
    2-[4-[N-(tert-butoxycarbonyl)-N-methoxymethylamino]-3-fluorophenyl]-6,8-difluoro-5-(4-methyl-3-pentenylamino)-4H-1-benzopyran-4-one
    —— 2-((5,7-dihydroxy-4-oxo-2-phenyl-4H-chromen-6-yl)oxy)acetic acid —— C17H12O7
    2-((5,7-dihydroxy-4-oxo-2-phenyl-4H-chromen-6-yl)oxy)acetic acid
    —— 2-(4-dioctylamino)phenyl-3-hydroxy-7-methoxy-4H-chromen-4-one —— C32H45NO4
    2-(4-dioctylamino)phenyl-3-hydroxy-7-methoxy-4H-chromen-4-one
    —— 3,3-bis(2,4-dimethoxyphenyl)-5-piperidinocarbonyl-3H-naphtho[2,1-b]pyran —— C35H35NO6
    3,3-bis(2,4-dimethoxyphenyl)-5-piperidinocarbonyl-3H-naphtho[2,1-b]pyran
    —— 8-(2-fluorophenethylaminomethyl)quercetin —— C24H20FNO7
    8-(2-fluorophenethylaminomethyl)quercetin
    —— fargenin A —— C24H22O13
    fargenin A
    —— 5,7-dihydroxy-3-(3-methylbut-2-enyl)-2-phenyl-4H-benzopyran-4-one —— C20H18O4
    5,7-dihydroxy-3-(3-methylbut-2-enyl)-2-phenyl-4H-benzopyran-4-one
    —— 5,7,3'-trimethoxyflavanone —— C18H18O5
    5,7,3'-trimethoxyflavanone
    —— 2-[4-(N-Acetyl)amino]phenyl-5-amino-4H-benzopyran-4-one —— C17H14N2O3
    2-[4-(N-Acetyl)amino]phenyl-5-amino-4H-benzopyran-4-one
    —— 2-methyl-7,7-diphenyl-7H-pyrano<3,2-e>benzoxazole —— C23H17NO2
    2-methyl-7,7-diphenyl-7H-pyrano<3,2-e>benzoxazole
    —— 8-{3-[4-(2-Methoxyphenyl)-1-piperazinyl]propylthiocarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran methanesulfonate —— CH4O3S*C31H33N3O3S
    8-{3-[4-(2-Methoxyphenyl)-1-piperazinyl]propylthiocarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran methanesulfonate
    —— 7-(3-(6-nitro-1H-benzo[d]imidazol-1-yl)propoxy)-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one —— C28H25N3O8
    7-(3-(6-nitro-1H-benzo[d]imidazol-1-yl)propoxy)-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one
    —— 4-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-1,2-phenylene dioctanoate —— C31H42O8
    4-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-1,2-phenylene dioctanoate
    —— taxifolin 7-α-O-glucoside —— C21H22O12
    taxifolin 7-α-O-glucoside
    —— hypolaetin 7-O-β-D-glucopyranoside —— C21H20O12
    hypolaetin 7-O-β-D-glucopyranoside
    —— flavopiridol —— C21H20ClNO5
    flavopiridol
    —— 2-(3,4-bis(palmitoyloxy)phenyl)-4-oxo-4H-chromene-3,5,7-triyl tripalmitate —— C95H160O12
    2-(3,4-bis(palmitoyloxy)phenyl)-4-oxo-4H-chromene-3,5,7-triyl tripalmitate
    —— 3',4'-O-(phenylbenzylidene)-3-O-ethylquercetin —— C30H22O7
    3',4'-O-(phenylbenzylidene)-3-O-ethylquercetin
    —— 1,3-dimethoxy-4-(3,4-dihydro-7-methoxy-2,4,4-trimethyl-2H-1-benzopyran-2-yl)benzene —— C21H26O4
    1,3-dimethoxy-4-(3,4-dihydro-7-methoxy-2,4,4-trimethyl-2H-1-benzopyran-2-yl)benzene
    —— 3-bromo-6-methoxy-2-phenyl-4H-chromen-4-one —— C16H11BrO3
    3-bromo-6-methoxy-2-phenyl-4H-chromen-4-one
    —— cyanidin 3-O-[2-O-(2-O-(trans-feruloyl)-3-O-(β-glucopyranosyl)-β-xylopyranosyl)-6-O-(4-O-(6-O-(trans-feruloyl)-β-glucopyranosyl)-trans-p-coumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside] —— C76H83O41
    cyanidin 3-O-[2-O-(2-O-(trans-feruloyl)-3-O-(β-glucopyranosyl)-β-xylopyranosyl)-6-O-(4-O-(6-O-(trans-feruloyl)-β-glucopyranosyl)-trans-p-coumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside]
    —— 7-geranoxy-5-hydroxy-8-methoxyflavone —— C26H28O5
    7-geranoxy-5-hydroxy-8-methoxyflavone
    —— 6-tert-butoxy-4-(4-chlorophenyl)-2-phenyl-2H-chromen-2-ol —— C25H23ClO3
    6-tert-butoxy-4-(4-chlorophenyl)-2-phenyl-2H-chromen-2-ol
    —— 3-hydroxy-2-(4-isopropylphenyl)-4H-chromen-4-one —— C18H16O3
    3-hydroxy-2-(4-isopropylphenyl)-4H-chromen-4-one
    —— (4cSR,8aSR)-2-phenyl-4c,7,8,8a-tetrahydrobenzo[b]-4H-furo[3,2-f]-1-benzopyran-4-one —— C21H16O3
    (4cSR,8aSR)-2-phenyl-4c,7,8,8a-tetrahydrobenzo[b]-4H-furo[3,2-f]-1-benzopyran-4-one
    —— (+)-6,8-bis(1-methylthioheptyl)catechin —— C31H46O6S2
    (+)-6,8-bis(1-methylthioheptyl)catechin
    —— 5-(3,5-dimethylphenyl)-2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinoline —— C28H29NO2
    5-(3,5-dimethylphenyl)-2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinoline
    —— 7-dodecyloxy-5-hydroxyflavone —— C27H34O4
    7-dodecyloxy-5-hydroxyflavone
    —— 2-(5-bromo-2-fluorophenyl)-3-(2-hydroxyethoxy)-4H-chromen-4-one —— C17H12BrFO4
    2-(5-bromo-2-fluorophenyl)-3-(2-hydroxyethoxy)-4H-chromen-4-one