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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-(2,3-dihydro-1-benzothiophen-6-ylmethyl)-N-hydroxyacetamide —— C11H13NO2S
    N-(2,3-dihydro-1-benzothiophen-6-ylmethyl)-N-hydroxyacetamide
    —— N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine
    —— N-(2,3-dihydro-1-benzothiophen-4-ylmethyl)-N-hydroxyacetamide —— C11H13NO2S
    N-(2,3-dihydro-1-benzothiophen-4-ylmethyl)-N-hydroxyacetamide
    —— (1R)-3-amino-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]propan-1-ol —— C12H17NOS
    (1R)-3-amino-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]propan-1-ol
    —— N-(2,3-dihydro-1-benzothiophen-7-ylmethyl)-N-hydroxyacetamide —— C11H13NO2S
    N-(2,3-dihydro-1-benzothiophen-7-ylmethyl)-N-hydroxyacetamide
    —— N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-4-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1S)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-6-yl]ethyl]hydroxylamine
    —— N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine —— C12H17NOS
    N-methyl-N-[(1R)-1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]ethyl]hydroxylamine
    —— 3-(2-fluorophenyl)-N'-[2-(4-methylphenyl)sulfanylacetyl]propanehydrazide —— C18H19FN2O2S
    3-(2-fluorophenyl)-N'-[2-(4-methylphenyl)sulfanylacetyl]propanehydrazide
    —— 3-(2-fluorophenyl)-N'-[2-(2-fluorophenyl)sulfanylacetyl]propanehydrazide —— C17H16F2N2O2S
    3-(2-fluorophenyl)-N'-[2-(2-fluorophenyl)sulfanylacetyl]propanehydrazide
    —— (E)-3-[5-(2-fluorophenyl)furan-2-yl]-N'-[2-(2-fluorophenyl)sulfanylacetyl]prop-2-enehydrazide —— C21H16F2N2O3S
    (E)-3-[5-(2-fluorophenyl)furan-2-yl]-N'-[2-(2-fluorophenyl)sulfanylacetyl]prop-2-enehydrazide
    —— (E)-N'-[2-(2-fluorophenyl)sulfanylacetyl]-3-(5-methylthiophen-2-yl)prop-2-enehydrazide —— C16H15FN2O2S2
    (E)-N'-[2-(2-fluorophenyl)sulfanylacetyl]-3-(5-methylthiophen-2-yl)prop-2-enehydrazide
    —— 2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]acetamide —— C21H22N2O2S
    2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]acetamide
    —— 3-(4-ethylphenyl)-N'-[2-(2-fluorophenyl)sulfanylacetyl]propanehydrazide —— C19H21FN2O2S
    3-(4-ethylphenyl)-N'-[2-(2-fluorophenyl)sulfanylacetyl]propanehydrazide
    —— 1-(3-chlorophenyl)-3-[[(2S)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea —— C17H18ClN3OS2
    1-(3-chlorophenyl)-3-[[(2S)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea
    —— (2S)-N'-[2-(3,5-dimethylpyrazol-1-yl)acetyl]-2-(4-methylphenyl)sulfanylpropanehydrazide —— C17H22N4O2S
    (2S)-N'-[2-(3,5-dimethylpyrazol-1-yl)acetyl]-2-(4-methylphenyl)sulfanylpropanehydrazide
    —— 1-(3-chlorophenyl)-3-[[(2R)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea —— C17H18ClN3OS2
    1-(3-chlorophenyl)-3-[[(2R)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea
    —— (2S)-2-(4-methylphenyl)sulfanyl-1-(4-thiophen-2-ylsulfonylpiperazin-1-yl)propan-1-one —— C18H22N2O3S3
    (2S)-2-(4-methylphenyl)sulfanyl-1-(4-thiophen-2-ylsulfonylpiperazin-1-yl)propan-1-one
    —— 5-[(2R)-3-amino-2-methylpropyl]-1-benzothiophen-3-one —— C12H15NOS
    5-[(2R)-3-amino-2-methylpropyl]-1-benzothiophen-3-one
    —— 5-[(2S)-1-aminobutan-2-yl]-1-benzothiophen-3-one —— C12H15NOS
    5-[(2S)-1-aminobutan-2-yl]-1-benzothiophen-3-one
    —— (2S)-N'-[2-(1-adamantyl)acetyl]-2-(4-methylphenyl)sulfanylpropanehydrazide —— C22H30N2O2S
    (2S)-N'-[2-(1-adamantyl)acetyl]-2-(4-methylphenyl)sulfanylpropanehydrazide
    —— 5-[(2S)-3-amino-2-methylpropyl]-1-benzothiophen-3-one —— C12H15NOS
    5-[(2S)-3-amino-2-methylpropyl]-1-benzothiophen-3-one
    —— (2R)-2-(4-methylphenyl)sulfanyl-1-(4-thiophen-2-ylsulfonylpiperazin-1-yl)propan-1-one —— C18H22N2O3S3
    (2R)-2-(4-methylphenyl)sulfanyl-1-(4-thiophen-2-ylsulfonylpiperazin-1-yl)propan-1-one
    —— (2R)-N-[2-(4-chlorophenyl)ethyl]-2-(4-methylphenyl)sulfanylpropanamide —— C18H20ClNOS
    (2R)-N-[2-(4-chlorophenyl)ethyl]-2-(4-methylphenyl)sulfanylpropanamide
    —— 5-[(2R)-1-aminobutan-2-yl]-1-benzothiophen-3-one —— C12H15NOS
    5-[(2R)-1-aminobutan-2-yl]-1-benzothiophen-3-one
    —— 2-(2,5-difluorophenyl)sulfanyl-N-[(2S)-2-phenylpropyl]acetamide —— C17H17F2NOS
    2-(2,5-difluorophenyl)sulfanyl-N-[(2S)-2-phenylpropyl]acetamide
    —— (2R)-N-[(3-chlorophenyl)methyl]-2-(4-methylphenyl)sulfanylpropanamide —— C17H18ClNOS
    (2R)-N-[(3-chlorophenyl)methyl]-2-(4-methylphenyl)sulfanylpropanamide
    —— 2-(2,5-difluorophenyl)sulfanyl-N-[(1S)-1-(4-fluorophenyl)ethyl]acetamide —— C16H14F3NOS
    2-(2,5-difluorophenyl)sulfanyl-N-[(1S)-1-(4-fluorophenyl)ethyl]acetamide
    —— (3S)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine —— C13H17NS
    (3S)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine
    —— (3R)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine —— C13H17NS
    (3R)-3-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine
    —— (3R)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine —— C13H17NS
    (3R)-3-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]pyrrolidine
    —— [1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]cyclopropyl]methanamine —— C13H17NS
    [1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]cyclopropyl]methanamine
    —— [1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropyl]methanamine —— C13H17NS
    [1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropyl]methanamine
    —— [1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]cyclopropyl]methanamine —— C13H17NS
    [1-[(2R)-2-methyl-2,3-dihydro-1-benzothiophen-7-yl]cyclopropyl]methanamine
    —— [1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropyl]methanamine —— C13H17NS
    [1-[(2S)-2-methyl-2,3-dihydro-1-benzothiophen-5-yl]cyclopropyl]methanamine
    —— 3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide —— C18H22FN3OS
    3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[(1S)-1-(4-fluorophenyl)ethyl]propanamide
    —— 2-(2,5-difluorophenyl)sulfanyl-N-[(1R)-1-(4-fluorophenyl)ethyl]acetamide —— C16H14F3NOS
    2-(2,5-difluorophenyl)sulfanyl-N-[(1R)-1-(4-fluorophenyl)ethyl]acetamide
    —— 1-tert-butyl-3-[[(2R)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea —— C15H23N3OS2
    1-tert-butyl-3-[[(2R)-2-(4-methylphenyl)sulfanylpropanoyl]amino]thiourea
    —— 1-Tert-butyl-3-[[2-(2,5-difluorophenyl)sulfanylacetyl]amino]thiourea —— C13H17F2N3OS2
    1-Tert-butyl-3-[[2-(2,5-difluorophenyl)sulfanylacetyl]amino]thiourea
    —— 1-Tert-butyl-3-(3-phenylsulfanylpropanoylamino)thiourea —— C14H21N3OS2
    1-Tert-butyl-3-(3-phenylsulfanylpropanoylamino)thiourea
    —— 1-Tert-butyl-3-[[2-(4-fluorophenyl)sulfanylacetyl]amino]thiourea —— C13H18FN3OS2
    1-Tert-butyl-3-[[2-(4-fluorophenyl)sulfanylacetyl]amino]thiourea