methyl 3-[7-(acetyloxy)-5-hydroxy-6,8-bis(isobut-2-en-1-yl)-4-oxo-4H-chromen-2-yl]-6-methoxy-2-(isobut-2-en-1-yl)phenyl-2,3,4-tris-O-acetyl-β-D-glucuronate | 1188911-07-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: methyl 3-[7-(acetyloxy)-5-hydroxy-6,8-bis(isobut-2-en-1-yl)-4-oxo-4H-chromen-2-yl]-6-methoxy-2-(isobut-2-en-1-yl)phenyl-2,3,4-tris-O-acetyl-β-D-glucuronate
• 英文别名: methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[3-[7-acetyloxy-5-hydroxy-6,8-bis(2-methylprop-2-enyl)-4-oxochromen-2-yl]-6-methoxy-2-(2-methylprop-2-enyl)phenoxy]oxane-2-carboxylate
• CAS: 1188911-07-0
• 化学式: C₄₃H₄₈O₁₆
• 分子量: 820.845
• InChiKey: XJAWOWCRDGFGJD-LELKPENRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  59
• 可旋转键数：
  20
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  206
• 氢给体数：
  1
• 氢受体数：
  16

文献信息

• Diosmetin compounds, a process for their preparation and pharmaceutical composition containing them
  申请人：Wierzbicki Michel

  公开号：US20090247621A1

  公开（公告）日：2009-10-01

  Compounds of formula (I): wherein R 1 , R 2 and R 3 , which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.

  化合物的化学式为(I)，其中R1，R2和R3可以相同也可以不同，分别代表氢原子或式(A)的基团。含有该化合物的药物制剂在预防和/或治疗静脉疾病和其他疾病方面是有用的。
• DIOSMETIN COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
  申请人：WIERZBICKI Michel

  公开号：US20120208777A1

  公开（公告）日：2012-08-16

  Compounds of formula (I): wherein R 1 , R 2 and R 3 , which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.
• US8138223B2
  申请人：——

  公开号：US8138223B2

  公开（公告）日：2012-03-20
• US8404742B2
  申请人：——

  公开号：US8404742B2

  公开（公告）日：2013-03-26