摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-(3-Ethoxyspiro[3.3]heptan-1-yl)-3-(5-methyl-2,3-dihydro-1-benzofuran-3-yl)urea —— C19H26N2O3
    1-(3-Ethoxyspiro[3.3]heptan-1-yl)-3-(5-methyl-2,3-dihydro-1-benzofuran-3-yl)urea
    —— N-[(3,4-diethyl-6-oxo-1H-pyridazin-5-yl)methyl]-2-methyl-2,3-dihydro-1-benzofuran-5-sulfonamide —— C18H23N3O4S
    N-[(3,4-diethyl-6-oxo-1H-pyridazin-5-yl)methyl]-2-methyl-2,3-dihydro-1-benzofuran-5-sulfonamide
    —— 1-(5-Methyl-2,3-dihydro-1-benzofuran-3-yl)-3-(2-methyl-2-methylsulfonylpropyl)urea —— C15H22N2O4S
    1-(5-Methyl-2,3-dihydro-1-benzofuran-3-yl)-3-(2-methyl-2-methylsulfonylpropyl)urea
    —— 3-[2-(3-fluorophenyl)ethyl-pent-2-enoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C30H35FN2O7
    3-[2-(3-fluorophenyl)ethyl-pent-2-enoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[cyclopropylmethyl(3-methoxypropanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C25H32N2O8
    3-[cyclopropylmethyl(3-methoxypropanoyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]acetamide —— C15H16N2O4S2
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]acetamide
    —— 1-(2,3-dihydro-1-benzofuran-5-yl)-3-[(4-methyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]urea —— C13H15N5O2S
    1-(2,3-dihydro-1-benzofuran-5-yl)-3-[(4-methyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]urea
    —— 5,6-dimethyl-N-(2-oxopiperidin-1-yl)-2,3-dihydro-1-benzofuran-2-carboxamide —— C16H20N2O3
    5,6-dimethyl-N-(2-oxopiperidin-1-yl)-2,3-dihydro-1-benzofuran-2-carboxamide
    —— (5Z)-5-[(2,2-dimethyl-3H-1-benzofuran-7-yl)methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one —— C18H20N2O3S
    (5Z)-5-[(2,2-dimethyl-3H-1-benzofuran-7-yl)methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one
    —— 3-[1-adamantylmethyl(cyclopropanecarbonyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C30H38N2O5
    3-[1-adamantylmethyl(cyclopropanecarbonyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— N-[(5-methoxy-2-methyl-2,3-dihydro-1-benzofuran-7-yl)methyl]-4-methylcyclohexan-1-amine —— C18H27NO2
    N-[(5-methoxy-2-methyl-2,3-dihydro-1-benzofuran-7-yl)methyl]-4-methylcyclohexan-1-amine
    —— 3-[cyclopentyl-(2-cyclopentylacetyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C29H38N2O7
    3-[cyclopentyl-(2-cyclopentylacetyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (5E)-2-cyclopentylimino-5-[(2,2-dimethyl-3H-1-benzofuran-5-yl)methylidene]-1,3-thiazolidin-4-one —— C19H22N2O2S
    (5E)-2-cyclopentylimino-5-[(2,2-dimethyl-3H-1-benzofuran-5-yl)methylidene]-1,3-thiazolidin-4-one
    —— 6-(2,3-Dihydro-1-benzofuran-5-ylmethylcarbamoyl)cyclohex-3-ene-1-carboxylic acid —— C17H19NO4
    6-(2,3-Dihydro-1-benzofuran-5-ylmethylcarbamoyl)cyclohex-3-ene-1-carboxylic acid
    —— 3-[cyclopentyl(octanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C30H44N2O7
    3-[cyclopentyl(octanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 5-(2,3-dihydro-1-benzofuran-5-yl)-N-[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]-1H-pyrazole-3-carboxamide —— C15H11F3N6O2
    5-(2,3-dihydro-1-benzofuran-5-yl)-N-[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]-1H-pyrazole-3-carboxamide
    —— 5-(2,3-dihydro-1-benzofuran-5-yl)-N-[5-(propan-2-yl)-1H-1,2,4-triazol-3-yl]-1H-pyrazole-3-carboxamide —— C17H18N6O2
    5-(2,3-dihydro-1-benzofuran-5-yl)-N-[5-(propan-2-yl)-1H-1,2,4-triazol-3-yl]-1H-pyrazole-3-carboxamide
    —— 5-(2,3-dihydro-1-benzofuran-5-yl)-N-(5-ethyl-1H-1,2,4-triazol-3-yl)-1H-pyrazole-3-carboxamide —— C16H16N6O2
    5-(2,3-dihydro-1-benzofuran-5-yl)-N-(5-ethyl-1H-1,2,4-triazol-3-yl)-1H-pyrazole-3-carboxamide
    —— 3-[(2-ethoxyacetyl)-(3-methylbutyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C26H38N2O8
    3-[(2-ethoxyacetyl)-(3-methylbutyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-(2,3-dihydro-1-benzofuran-5-yl)-N-[6-(trifluoromethyl)pyridin-3-yl]-1H-pyrazole-5-carboxamide —— C18H13F3N4O2
    3-(2,3-dihydro-1-benzofuran-5-yl)-N-[6-(trifluoromethyl)pyridin-3-yl]-1H-pyrazole-5-carboxamide
    —— 3-(2,3-dihydro-1-benzofuran-5-yl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)propanamide —— C15H19NO4S
    3-(2,3-dihydro-1-benzofuran-5-yl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)propanamide
    —— 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2S)-1-hydroxy-3-methylpentan-2-yl]acetamide —— C16H23NO3
    2-(2,3-dihydro-1-benzofuran-5-yl)-N-[(2S)-1-hydroxy-3-methylpentan-2-yl]acetamide
    —— 2-(2,3-Dihydro-1-benzofuran-5-YL)-N-[(2S)-1-hydroxy-4-(methylsulfanyl)butan-2-YL]acetamide —— C15H21NO3S
    2-(2,3-Dihydro-1-benzofuran-5-YL)-N-[(2S)-1-hydroxy-4-(methylsulfanyl)butan-2-YL]acetamide
    —— 3-methoxy-3-(4-nitrophenyl)-2H-1-benzofuran —— C15H13NO4
    3-methoxy-3-(4-nitrophenyl)-2H-1-benzofuran
    —— 3-[3-ethoxypropyl(octanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C28H42N2O6
    3-[3-ethoxypropyl(octanoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3-[2-methoxyethyl(5-oxohexanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C26H36N2O9
    4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3-[2-methoxyethyl(5-oxohexanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[cyclopentyl(3-methylbut-2-enoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C25H32N2O5
    3-[cyclopentyl(3-methylbut-2-enoyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[(2,4-dichlorophenyl)methyl-hept-6-enoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C31H36Cl2N2O7
    3-[(2,4-dichlorophenyl)methyl-hept-6-enoylamino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-[cyclohexylmethyl(oxolane-2-carbonyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C29H38N2O8
    3-[cyclohexylmethyl(oxolane-2-carbonyl)amino]-8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— N-((5-(thiophen-2-yl)pyridin-3-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide —— C18H16N2O3S2
    N-((5-(thiophen-2-yl)pyridin-3-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide
    —— N-(2-(5-chlorothiophen-2-yl)-2-methoxyethyl)-2,3-dihydrobenzofuran-5-sulfonamide —— C15H16ClNO4S2
    N-(2-(5-chlorothiophen-2-yl)-2-methoxyethyl)-2,3-dihydrobenzofuran-5-sulfonamide
    —— N-(2-(5-chlorothiophen-2-yl)-2-methoxyethyl)-2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetamide —— C19H22ClNO4S
    N-(2-(5-chlorothiophen-2-yl)-2-methoxyethyl)-2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetamide
    —— 3-[1-adamantylmethyl-(2-ethoxyacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C32H44N2O8
    3-[1-adamantylmethyl-(2-ethoxyacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-((2-(thiophen-3-yl)pyridin-3-yl)methyl)acetamide —— C22H22N2O3S
    2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-((2-(thiophen-3-yl)pyridin-3-yl)methyl)acetamide
    —— N-((2-(thiophen-3-yl)pyridin-3-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide —— C18H16N2O3S2
    N-((2-(thiophen-3-yl)pyridin-3-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide
    —— N-(2-(2,4-dioxooxazolidin-3-yl)-1-phenylethyl)-2,3-dihydrobenzofuran-5-sulfonamide —— C19H18N2O6S
    N-(2-(2,4-dioxooxazolidin-3-yl)-1-phenylethyl)-2,3-dihydrobenzofuran-5-sulfonamide
    —— 1-((1-(1-(2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetyl)azetidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)pyrrolidin-2-one —— C22H27N5O4
    1-((1-(1-(2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetyl)azetidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)pyrrolidin-2-one
    —— N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide —— C19H22N2O4S
    N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)-2,3-dihydrobenzofuran-5-sulfonamide
    —— 3-[cyclopropanecarbonyl-[2-(2-methoxyphenyl)ethyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C28H32N2O6
    3-[cyclopropanecarbonyl-[2-(2-methoxyphenyl)ethyl]amino]-4-hydroxy-N-(2-hydroxyethyl)-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— (4-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperazin-1-yl)(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)methanone —— C20H24N4O4S
    (4-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperazin-1-yl)(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)methanone
    —— 4-hydroxy-N-(2-hydroxyethyl)-3-[2-methylpropanoyl(3-propan-2-yloxypropyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C25H36N2O6
    4-hydroxy-N-(2-hydroxyethyl)-3-[2-methylpropanoyl(3-propan-2-yloxypropyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)acetamide —— C23H28N2O4
    2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)acetamide
    —— 3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile —— C18H18N4O4S
    3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
    —— 8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3-[oxolan-2-ylmethyl(propanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C25H32N2O8
    8-formyl-4-hydroxy-N-(2-hydroxyethyl)-6-methoxy-3-[oxolan-2-ylmethyl(propanoyl)amino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 4-hydroxy-N-(2-hydroxyethyl)-3-[2-(2-methoxyphenyl)ethyl-pentanoylamino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C29H36N2O6
    4-hydroxy-N-(2-hydroxyethyl)-3-[2-(2-methoxyphenyl)ethyl-pentanoylamino]-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)-6-methylpyridazine —— C18H21N3O4S
    3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)-6-methylpyridazine
    —— 3-[cyclopentyl-(2-cyclopentylacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide —— C29H40N2O7
    3-[cyclopentyl-(2-cyclopentylacetyl)amino]-4-hydroxy-N-(2-hydroxyethyl)-8-(hydroxymethyl)-6-methoxy-3,4,4a,9b-tetrahydrodibenzofuran-1-carboxamide
    —— 2-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)pyrazine —— C17H19N3O4S
    2-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)piperidin-3-yl)oxy)pyrazine
    —— 6-((1-((2,3-dihydrobenzofuran-5-yl)sulfonyl)pyrrolidin-3-yl)oxy)-N,N-dimethylpyridazin-3-amine —— C18H22N4O4S
    6-((1-((2,3-dihydrobenzofuran-5-yl)sulfonyl)pyrrolidin-3-yl)oxy)-N,N-dimethylpyridazin-3-amine
    —— 3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)pyrrolidin-3-yl)oxy)-6-methoxypyridazine —— C17H19N3O5S
    3-((1-((2,3-Dihydrobenzofuran-5-yl)sulfonyl)pyrrolidin-3-yl)oxy)-6-methoxypyridazine