摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 香豆素

    香豆素

    香豆素 基本信息

    香豆素（Coumarin）是一类具有独特芳香气味的化合物，化学式为C9H6O2。它们属于苯骈α-呋喃酮类化合物，在自然界中广泛存在。

    结构特征

    香豆素的基本结构由苯环和呋喃酮构成，其中苯环与四个碳原子相连的呋喃酮单元形成独特的“香豆素环”。

    自然来源

    香豆素存在于多种植物、真菌及动物体内。在植物界中，它主要作为天然防御机制的一部分，用作对昆虫的化学信号。著名的例子包括：天竺葵科（如紫花苜蓿）、唇形科（如薄荷）和芸香科（如柑橘属果实）。此外，在真菌、苔藓及藻类中也有发现。

    化学性质 稳定性

    由于其独特的结构，香豆素表现出良好的化学稳定性。它们不易被氧化或还原，但可以与其他化合物发生多种类型的反应，包括缩合、取代等。

    生物活性

    许多香豆素衍生物具有生物活性，能够引起抗菌、抗炎、抗氧化等多种作用。这些特性使它们成为医药、食品添加剂等多个领域的重要研究对象。

    应用领域 医药行业

    在制药业中，某些结构类似物被开发为药物先导化合物。例如，香豆素类抗生素是最早的广谱抗生素之一；一些香豆素衍生物还表现出抗癌潜力。

    食品工业

    由于其独特的香气和味道，在食品加工中也得到了广泛应用，常作为香精成分使用。

    其他应用

    此外，它们还在染料生产、农药开发等多个领域展现出潜在价值。

    生产方法

    香豆素可通过多种合成路径获得。传统的化学合成涉及从苯甲醛出发的反应；而近年来，通过生物转化技术，利用微生物发酵过程制备天然香豆素也成为一种可持续的方法。

    总之，香豆素因其独特的结构和广泛的生物学应用，在多个领域中发挥着重要作用，并且仍然是有机化学研究中的一个重要课题。

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[6-bromo-2-hydroxy-5-(4-hydroxy-4-methylpent-2-enyl)-5,8a-dimethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C27H37BrO5
    2-[6-bromo-2-hydroxy-5-(4-hydroxy-4-methylpent-2-enyl)-5,8a-dimethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 7-Chloro-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-ol —— C11H13ClO3
    7-Chloro-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-ol
    —— 3-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C12H14O5
    3-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 7-(8-Hydroxy-1,2,3,4,4a,9b-hexahydrodibenzofuran-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid —— C21H24O5
    7-(8-Hydroxy-1,2,3,4,4a,9b-hexahydrodibenzofuran-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid
    —— 5-Methoxy-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-6-ol —— C12H14O3
    5-Methoxy-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-6-ol
    —— 2-(Hydroxymethyl)-5-(2-hydroxy-5-prop-2-enylphenyl)-2,3-dihydro-1-benzofuran-3-ol —— C18H18O4
    2-(Hydroxymethyl)-5-(2-hydroxy-5-prop-2-enylphenyl)-2,3-dihydro-1-benzofuran-3-ol
    —— 1-(5-Methoxy-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-4-yl)ethanol —— C14H18O3
    1-(5-Methoxy-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-4-yl)ethanol
    —— 7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-6-pentyl-2,3-dihydro-1-benzofuran-3-ol —— C17H26O4
    7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-6-pentyl-2,3-dihydro-1-benzofuran-3-ol
    —— 6a-hydroxy-3,9-dimethoxypterocarpan —— C17H18O5
    6a-hydroxy-3,9-dimethoxypterocarpan
    —— 2,3-dihydro-2-methylbenzofuran-4-carboxylic acid 1261963-74-9 C10H10O3
    2,3-dihydro-2-methylbenzofuran-4-carboxylic acid
    —— 6-methoxy-2,3,3-trimethyl-4-phenyl-2H-1-benzofuran —— C18H20O2
    6-methoxy-2,3,3-trimethyl-4-phenyl-2H-1-benzofuran
    —— 3-[2-(2-Hydroxypropan-2-yl)-4-[2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-2,3-dihydro-1-benzofuran-5-yl]propanoic acid —— C21H30O9
    3-[2-(2-Hydroxypropan-2-yl)-4-[2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-2,3-dihydro-1-benzofuran-5-yl]propanoic acid
    —— 2-(1-Acetyloxy-2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C14H16O6
    2-(1-Acetyloxy-2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 2-[5-(3-Hydroxyprop-1-enyl)-7-methoxy-2,3-dihydro-1-benzofuran-2-yl]propan-2-ol —— C15H20O4
    2-[5-(3-Hydroxyprop-1-enyl)-7-methoxy-2,3-dihydro-1-benzofuran-2-yl]propan-2-ol
    —— 1,1,4a,6-tetramethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-6,7-dihydro-3H-furo[3,2-g][1]benzofuran]-2,4',7'-triol —— C23H32O5
    1,1,4a,6-tetramethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-6,7-dihydro-3H-furo[3,2-g][1]benzofuran]-2,4',7'-triol
    —— Methyl 2-[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-6-yl]acetate —— C14H18O4
    Methyl 2-[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-6-yl]acetate
    —— Ethyl 4-hydroxy-3-(4-hydroxyphenyl)-2-[[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl]-5-oxofuran-2-carboxylate —— C25H26O8
    Ethyl 4-hydroxy-3-(4-hydroxyphenyl)-2-[[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl]-5-oxofuran-2-carboxylate
    —— 2-Prop-1-en-2-yl-2,3-dihydro-1-benzofuran-6-ol —— C11H12O2
    2-Prop-1-en-2-yl-2,3-dihydro-1-benzofuran-6-ol
    —— 2-(2-Hydroxy-6-methylhept-5-en-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C17H22O4
    2-(2-Hydroxy-6-methylhept-5-en-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 3-Hydroxy-2-(1,2,3-trihydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carbaldehyde —— C12H14O6
    3-Hydroxy-2-(1,2,3-trihydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carbaldehyde
    —— 5-(2,3-dihydro-1-benzofuran-5-yl)-N-[3-(morpholin-4-yl)propyl]-1H-pyrazole-3-carboxamide —— C19H24N4O3
    5-(2,3-dihydro-1-benzofuran-5-yl)-N-[3-(morpholin-4-yl)propyl]-1H-pyrazole-3-carboxamide
    —— 2-Hydroxy-1-[4-hydroxy-7-(3-methylbut-2-enyl)-2-(3,3,5-trimethylhex-4-enyl)-2,3-dihydro-1-benzofuran-5-yl]ethanone —— C24H34O4
    2-Hydroxy-1-[4-hydroxy-7-(3-methylbut-2-enyl)-2-(3,3,5-trimethylhex-4-enyl)-2,3-dihydro-1-benzofuran-5-yl]ethanone
    —— 2-[5-(Hydroxymethyl)-2,3-dihydro-1-benzofuran-2-yl]propane-1,2-diol —— C12H16O4
    2-[5-(Hydroxymethyl)-2,3-dihydro-1-benzofuran-2-yl]propane-1,2-diol
    —— 2,3-Dihydro-N-[2-(1H-imidazol-5-yl)ethyl]-6-benzofuranacetamide —— C15H17N3O2
    2,3-Dihydro-N-[2-(1H-imidazol-5-yl)ethyl]-6-benzofuranacetamide
    —— Methyl 7-hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylate —— C13H16O5
    Methyl 7-hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-carboxylate
    —— 3,3a-Dimethyl-3,8b-dihydrocyclopenta[b][1]benzofuran —— C13H14O
    3,3a-Dimethyl-3,8b-dihydrocyclopenta[b][1]benzofuran
    —— Methyl 3-(3-(2-(2,3-dihydrobenzofuran-5-yl)ethoxy)-4-methoxyphenyl)-3-(1-(3,4-dihydroxyphenethyl)-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)propanoate —— C35H37NO9
    Methyl 3-(3-(2-(2,3-dihydrobenzofuran-5-yl)ethoxy)-4-methoxyphenyl)-3-(1-(3,4-dihydroxyphenethyl)-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)propanoate
    —— 9-Methoxy-11-oxatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene —— C17H20O2
    9-Methoxy-11-oxatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene
    —— N-(2,3-dihydro-1-benzofuran-2-ylmethyl)-2-[2-(4-methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-b]pyran-3-yl]acetamide —— C26H23NO6
    N-(2,3-dihydro-1-benzofuran-2-ylmethyl)-2-[2-(4-methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-b]pyran-3-yl]acetamide
    —— 3-Hydroxy-2-(2-hydroxypropan-2-yl)-7-(3-methylbut-2-enyl)-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C17H22O5
    3-Hydroxy-2-(2-hydroxypropan-2-yl)-7-(3-methylbut-2-enyl)-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 2-(2,3-dihydro-1-benzofuran-6-yl)-N-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}acetamide —— C23H27NO4
    2-(2,3-dihydro-1-benzofuran-6-yl)-N-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}acetamide
    —— 2-[6-bromo-2-hydroxy-5,8a-dimethyl-5-(4-methyl-3-oxopent-4-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C27H35BrO5
    2-[6-bromo-2-hydroxy-5,8a-dimethyl-5-(4-methyl-3-oxopent-4-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 1-(2-Prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)propane-1,2-diol —— C14H18O3
    1-(2-Prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)propane-1,2-diol
    —— 2-[6-bromo-2-hydroxy-5,8a-dimethyl-5-(4-methylpent-3-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid —— C27H37BrO4
    2-[6-bromo-2-hydroxy-5,8a-dimethyl-5-(4-methylpent-3-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-yl]-2,3-dihydro-1-benzofuran-5-carboxylic acid
    —— 5-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(4-hydroxyphenyl)ethyl]-1H-pyrazole-3-carboxamide —— C20H19N3O3
    5-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(4-hydroxyphenyl)ethyl]-1H-pyrazole-3-carboxamide
    —— 3-[5-(3-Methoxybuta-1,3-dienyl)-2,3-dihydro-1-benzofuran-2-yl]pentan-3-ol —— C18H24O3
    3-[5-(3-Methoxybuta-1,3-dienyl)-2,3-dihydro-1-benzofuran-2-yl]pentan-3-ol
    —— methyl 2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran-5-carboxylate —— C13H14O3
    methyl 2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran-5-carboxylate
    —— 1-[5-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-4-yl]-2-methylpropan-1-one —— C15H20O4
    1-[5-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-4-yl]-2-methylpropan-1-one
    —— Methyl 3-(2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)prop-2-enoate —— C15H16O3
    Methyl 3-(2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)prop-2-enoate
    —— 1-[3-(3-Methylbutanoyloxy)-2-(3-oxoprop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-yl]ethyl 2-methylbutanoate —— C23H30O6
    1-[3-(3-Methylbutanoyloxy)-2-(3-oxoprop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-yl]ethyl 2-methylbutanoate
    —— 1-[2-(3-Oxoprop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-yl]ethyl 2-methylbut-2-enoate —— C18H20O4
    1-[2-(3-Oxoprop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-yl]ethyl 2-methylbut-2-enoate
    —— methyl3-[5-[2-(2,3-dihydro-1-benzofuran-5-yl)ethoxy]-4-methoxycyclohepta-1,3,6-trien-1-yl]-3-[2-[6,7-dihydroxy-4-(4,5-dihydroxycyclohexa-1,3-dien-1-yl)cyclohexa-1,5-dien-1-yl]ethyl-hydroxy-5-oxo-1-azacyclohepta-3,6-dien-4-yl]propanoate —— C35H37NO9
    methyl3-[5-[2-(2,3-dihydro-1-benzofuran-5-yl)ethoxy]-4-methoxycyclohepta-1,3,6-trien-1-yl]-3-[2-[6,7-dihydroxy-4-(4,5-dihydroxycyclohexa-1,3-dien-1-yl)cyclohexa-1,5-dien-1-yl]ethyl-hydroxy-5-oxo-1-azacyclohepta-3,6-dien-4-yl]propanoate
    —— 2-(5-Formyl-2,3-dihydro-1-benzofuran-2-yl)prop-2-enyl 2-methylpropanoate —— C16H18O4
    2-(5-Formyl-2,3-dihydro-1-benzofuran-2-yl)prop-2-enyl 2-methylpropanoate
    —— 4-(2-hydroxy-5,7-dimethyl-3H-1-benzofuran-2-yl)piperidine-2,6-dione —— C15H17NO4
    4-(2-hydroxy-5,7-dimethyl-3H-1-benzofuran-2-yl)piperidine-2,6-dione
    —— 2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran-5-carbaldehyde 69745-01-3 C12H12O2
    2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran-5-carbaldehyde
    —— [2-(Hydroxymethyl)-6-[3-(hydroxymethyl)-2-methoxy-2,3-dihydro-1-benzofuran-6-yl]-2,3-dihydro-1-benzofuran-3-yl]methanol —— C20H22O6
    [2-(Hydroxymethyl)-6-[3-(hydroxymethyl)-2-methoxy-2,3-dihydro-1-benzofuran-6-yl]-2,3-dihydro-1-benzofuran-3-yl]methanol
    —— 2-Hydroxy-1-(2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)propan-1-one —— C14H16O3
    2-Hydroxy-1-(2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl)propan-1-one
    —— 1-[7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-6-yl]propane-1,2-diol —— C15H22O5
    1-[7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-6-yl]propane-1,2-diol
    —— methyl 2-methyl-2,3-dihydrobenzofuran-7-carboxylate 41176-57-2 C11H12O3
    methyl 2-methyl-2,3-dihydrobenzofuran-7-carboxylate
    —— 2-(2,3-Dihydro-1-benzofuran-6-YL)-N-[3-(morpholin-4-YL)propyl]acetamide —— C17H24N2O3
    2-(2,3-Dihydro-1-benzofuran-6-YL)-N-[3-(morpholin-4-YL)propyl]acetamide